PHLDA3 inhibition attenuates endoplasmic reticulum stress‑induced apoptosis in myocardial hypoxia/reoxygenation injury by activating the PI3K/AKT signaling pathway

Experimental and Therapeutic Medicine ◽

10.3892/etm.2021.10045 ◽

2021 ◽

Vol 21 (6) ◽

Author(s):

Kai Liu ◽

Ying Chen ◽

Fen Ai ◽

Yun-Qian Li ◽

Kun Zhang ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Myocardial Hypoxia ◽

Reoxygenation Injury ◽

Induced Apoptosis ◽

Hypoxia Reoxygenation

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Puerarin attenuates myocardial hypoxia/reoxygenation injury by inhibiting autophagy via the Akt signaling pathway

Molecular Medicine Reports ◽

10.3892/mmr.2017.6424 ◽

2017 ◽

Vol 15 (6) ◽

pp. 3747-3754 ◽

Author(s):

Huixiong Tang ◽

Xudong Song ◽

Yuanna Ling ◽

Xianbao Wang ◽

Pingzhen Yang ◽

...

Keyword(s):

Signaling Pathway ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Myocardial Hypoxia ◽

Reoxygenation Injury ◽

Hypoxia Reoxygenation

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Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway

Toxicology in Vitro ◽

10.1016/j.tiv.2017.03.003 ◽

2017 ◽

Vol 41 ◽

pp. 232-244 ◽

Author(s):

Yujing Zhang ◽

Fang Xiao ◽

Xinmin Liu ◽

Kaihua Liu ◽

Xiaoxin Zhou ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Mitochondrial Dysfunction ◽

Signaling Pathway ◽

Akt Signaling ◽

Akt Signaling Pathway

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Schisantherin A protects renal tubular epithelial cells from hypoxia/reoxygenation injury through the activation of PI3K/Akt signaling pathway

Journal of Biochemical and Molecular Toxicology ◽

10.1002/jbt.22160 ◽

2018 ◽

Vol 32 (7) ◽

pp. e22160 ◽

Author(s):

Jiachuan Gong ◽

Xuezhen Wang

Keyword(s):

Epithelial Cells ◽

Signaling Pathway ◽

Akt Signaling ◽

Tubular Epithelial Cells ◽

Akt Signaling Pathway ◽

Renal Tubular Epithelial Cells ◽

Reoxygenation Injury ◽

Renal Tubular ◽

Schisantherin A ◽

Hypoxia Reoxygenation

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Wogonin induces apoptosis and endoplasmic reticulum stress in HL-60 leukemia cells through inhibition of the PI3K-AKT signaling pathway

Oncology Reports ◽

10.3892/or.2015.3896 ◽

2015 ◽

Vol 33 (6) ◽

pp. 3146-3154 ◽

Author(s):

CHENGJUN HU ◽

MAOZHONG XU ◽

RUJUAN QIN ◽

WEIFENG CHEN ◽

XIN XU

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Akt Signaling ◽

Leukemia Cells ◽

Akt Signaling Pathway

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Panax quinquefolium Saponins Reduce Myocardial Hypoxia-Reoxygenation Injury by Inhibiting Excessive Endoplasmic Reticulum Stress

Shock ◽

10.1097/shk.0b013e31823f15c4 ◽

2012 ◽

Vol 37 (2) ◽

pp. 228-233 ◽

Author(s):

Chen Wang ◽

Yu-Zhen Li ◽

Xiao-Reng Wang ◽

Zhen-Rong Lu ◽

Da-Zhuo Shi ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Panax Quinquefolium ◽

Myocardial Hypoxia ◽

Reoxygenation Injury ◽

Hypoxia Reoxygenation

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GW25-e5238 Lycopene protects endoplasmic reticulum stress induced apoptosis against neonatal mouse cardiomyocytes hypoxia/reoxygenation injury

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2014.06.129 ◽

2014 ◽

Vol 64 (16) ◽

pp. C26-C27

Author(s):

Jiqian Xu ◽

Houxiang Hu ◽

Bin Chen ◽

Zhou Zhou ◽

Lei Xu ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Neonatal Mouse ◽

Reoxygenation Injury ◽

Induced Apoptosis ◽

Hypoxia Reoxygenation

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Hesperetin post-treatment prevents rat cardiomyocytes from hypoxia/reoxygenation injury in vitro via activating PI3K/Akt signaling pathway

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2017.05.003 ◽

2017 ◽

Vol 91 ◽

pp. 1106-1112 ◽

Author(s):

Shangfei He ◽

Xianbao Wang ◽

Yongkang Zhong ◽

Lu Tang ◽

Ya Zhang ◽

...

Keyword(s):

Signaling Pathway ◽

Akt Signaling ◽

Post Treatment ◽

Akt Signaling Pathway ◽

Rat Cardiomyocytes ◽

Reoxygenation Injury ◽

Hypoxia Reoxygenation

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Shikonin protects H9C2 cardiomyocytes against hypoxia/reoxygenation injury through activation of PI3K/Akt signaling pathway

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2018.04.144 ◽

2018 ◽

Vol 104 ◽

pp. 712-717 ◽

Author(s):

Shuang Wang ◽

Yanfang Zhu ◽

Ruixia Qiu

Keyword(s):

Signaling Pathway ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

H9c2 Cardiomyocytes ◽

Reoxygenation Injury ◽

Hypoxia Reoxygenation

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Icariin Inhibits Endoplasmic Reticulum Stress-induced Neuronal Apoptosis after Spinal Cord Injury through Modulating the PI3K/AKT Signaling Pathway

International Journal of Biological Sciences ◽

10.7150/ijbs.30348 ◽

2019 ◽

Vol 15 (2) ◽

pp. 277-286 ◽

Author(s):

Haotian Li ◽

Xinran Zhang ◽

Xi Qi ◽

Xu Zhu ◽

Liming Cheng

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Neuronal Apoptosis ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

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Dexmedetomidine reversed hypoxia/reoxygenation injury-induced oxidative stress and endoplasmic reticulum stress-dependent apoptosis of cardiomyocytes via SIRT1/CHOP signaling pathway

Molecular and Cellular Biochemistry ◽

10.1007/s11010-021-04102-8 ◽

2021 ◽

Author(s):

Ying Zhang ◽

Qihong Zhao ◽

Xiaohong Li ◽

Fuhai Ji

Keyword(s):

Oxidative Stress ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Reoxygenation Injury ◽

Stress Dependent ◽

Hypoxia Reoxygenation

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