Report from the OMERACT Hand Osteoarthritis Special Interest Group: Advances and Future Research Priorities

2014 ◽  
Vol 41 (4) ◽  
pp. 810-818 ◽  
Author(s):  
Margreet Kloppenburg ◽  
Pernille Bøyesen ◽  
Wilma Smeets ◽  
Ida Haugen ◽  
Rani Liu ◽  
...  
Keyword(s):  
Outcome Measures ◽  
Interest Group ◽  
Special Interest ◽  
Disease Process ◽  
Research Priorities ◽  
Special Interest Group ◽  
Future Research ◽  
Hand Osteoarthritis ◽  
Record Keeping ◽  
Delphi Exercise

Osteoarthritis (OA) is one of the most common musculoskeletal disorders, frequently affecting the hands. In the last decade there has been increased awareness concerning this disorder because of its clinical burden. Unfortunately, only limited treatments for symptom alleviation are available, and no effective treatment for disease modification exists. The lack of treatment is due not only to a lack of understanding of the disease process, but also to poor outcome measures to assess the condition. The OMERACT Hand OA Special Interest Group (SIG) has started to develop a core set of outcome measures for hand OA clinical trials, observational studies, and clinical record keeping. At OMERACT 11, results from a Delphi exercise were presented, and a preliminary set of core domains was discussed. The group attempted to adopt the new OMERACT Filter 2.0 in the process, and literature overviews of conventional radiographs, ultrasonography, and magnetic resonance imaging as outcome measures in hand OA were presented. Discussions that followed highlighted further suggestions for core domains, the heterogeneity of hand OA, and future research priorities.

scholarly journals Patient-reported Outcomes and Adult Patients’ Disease Experience in the Idiopathic Inflammatory Myopathies. Report from the OMERACT 11 Myositis Special Interest Group

2014 ◽  
Vol 41 (3) ◽  
pp. 581-592 ◽  
Author(s):  
Helene Alexanderson ◽  
Maria Del Grande ◽  
Clifton O. Bingham ◽  
Ana-Maria Orbai ◽  
Catherine Sarver ◽  
...  
Keyword(s):  
Outcome Measures ◽  
Interest Group ◽  
Special Interest ◽  
Patient Reported Outcome Measures ◽  
Patient Reported Outcome ◽  
Special Interest Group ◽  
Idiopathic Inflammatory Myopathies ◽  
Inflammatory Myopathies ◽  
Emotional Life ◽  
Patient Reported

The newly formed Outcome Measures in Rheumatology (OMERACT) Myositis Special Interest Group (SIG) was established to examine patient-reported outcome measures (PROM) in myositis. At OMERACT 11, a literature review of PROM used in the idiopathic inflammatory myopathies (IIM) and other neuromuscular conditions was presented. The group examined in more detail 2 PROM more extensively evaluated in patients with IIM, the Myositis Activities Profile, and the McMaster-Toronto Arthritis Patient Preference Disability Questionnaire, through the OMERACT filter of truth, discrimination, and feasibility. Preliminary results from a qualitative study of patients with myositis regarding their symptoms were discussed that emphasized the range of symptoms experienced: pain, physical tightness/stiffness, fatigue, disease effect on emotional life and relationships, and treatment-related side effects. Following discussion of these results and following additional discussions since OMERACT 11, a research agenda was developed. The next step in evaluating PROM in IIM will require additional focus groups with a spectrum of patients with different myositis disease phenotypes and manifestations across a range of disease activity, and from multiple international settings. The group will initially focus on dermatomyositis and polymyositis in adults. Qualitative analysis will facilitate the identification of commonalities and divergent patient-relevant aspects of disease, insights that are critical given the heterogeneous manifestations of these diseases. Based on these qualitative studies, existing myositis PROM can be examined to more thoroughly assess content validity, and will be important to identify gaps in domain measurement that will be required to develop a preliminary core set of patient-relevant domains for IIM.

scholarly journals e-INEBRIA Special Interest Group Roadmap for Best Practices for Research on Brief Digital Interventions for Problematic Alcohol and Illicit Drug Use (Preprint)

2020 ◽  
Author(s):  
Michael Patrick Schaub ◽  
Anne H Berman ◽  
Hugo López Pelayo ◽  
Nikolaos Boumparis ◽  
Zarnie Khadjesari ◽  
...  
Keyword(s):  
Drug Use ◽  
Interest Group ◽  
Special Interest ◽  
Illicit Drug ◽  
Illicit Drug Use ◽  
Special Interest Group ◽  
Brief Interventions ◽  
Future Research ◽  
Digital Interventions ◽  
Starting Point

UNSTRUCTURED There is great potential for scaling up the delivery of brief interventions for alcohol and illicit drug use, given the increasing coverage of mobile devices and technologies for digital interventions, including apps for smartphones and tablets. However, while the number of digital interventions is increasing rapidly, the involvement of brief-intervention researchers and the development of good practices has just begun. In 2018, the Special Interest Group on digital interventions of the International Network on Brief Interventions for Alcohol & Other Drugs (e-INEBRIA SIG) initiated a conversation regarding possible avenues of future research, which subsequently became a roadmap for digital interventions. This roadmap consists of points considered relevant for future research, ongoing technological developments, and their implementation across a continuum of prevention and care. Moreover, it outlines starting points for the diversification of brief digital interventions, as well as next steps for quality improvement and implementation in public health and clinical practice. The roadmap of the e-INEBRIA SIG on digital interventions is a starting point that indicates relevant next steps and provides orientation for researchers and interested practitioners with regard to the ambiguous literature and the complexity of current digital interventions.

Developing a Standardized Definition for Disease “Flare” in Rheumatoid Arthritis (OMERACT 9 Special Interest Group): Table 1.

2009 ◽  
Vol 36 (10) ◽  
pp. 2335-2341 ◽  
Author(s):  
CLIFTON O. BINGHAM ◽  
CHRISTOPH POHL ◽  
THASIA G. WOODWORTH ◽  
SARAH E. HEWLETT ◽  
JAMES E. MAY ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Interest Group ◽  
Special Interest ◽  
Disease Activity Score ◽  
Special Interest Group ◽  
Critical Elements ◽  
Working Definition ◽  
Delphi Exercise ◽  
Definition Of

Objective.Traditional outcome measures in randomized controlled trials (RCT) include well-established response criteria as well as ACR EULAR responses using Disease Activity Score 44 (DAS44)/DAS28 to assess improvement; however, a measure to assess worsening of disease has yet to be developed. This special interest group (SIG) was established to develop an evidence-based, consensus-driven standard definition of “flare” in rheumatoid arthritis (RA).Methods.At OMERACT 8, the need for a standardized definition of RA flare was recognized; interested individuals developed a proposal to form a SIG. A literature review was performed to identify publications and abstracts with flare definitions applied in RA, JIA, and lupus RCT as well as concerning patient perspectives on disease worsening. A SIG was held at OMERACT 9 with breakout sessions for patients and investigators.Results.The RA flare SIG was attended by about 120 participants, including 11 patients. Patients and investigators held separate breakout sessions to discuss various aspects of disease worsening. The following consensus was obtained at OMERACT 9: a working definition of flare should indicate worsening of disease activity (88%), persistence, and duration as critical elements (77%), and consideration of change or increase in therapy (74%).Conclusion.A working definition of RA flare was developed based on these votes: flare is any worsening of disease activity that would, if persistent, in most cases lead to initiation or change of therapy; and a flare represents a cluster of symptoms of sufficient duration and intensity to require initiation, change, or increase in therapy. Using this working definition, evaluation of candidate domains will be conducted via Delphi exercise and further informed by patient focus groups. Validation of candidate definitions in appropriate RCT will be required.

scholarly journals Evidence for Updating the Core Domain Set of Outcome Measures for Juvenile Idiopathic Arthritis: Report from a Special Interest Group at OMERACT 2016

2017 ◽  
Vol 44 (12) ◽  
pp. 1884-1888 ◽  
Author(s):  
Esi M. Morgan ◽  
Meredith P. Riebschleger ◽  
Jennifer Horonjeff ◽  
Alessandro Consolaro ◽  
Jane E. Munro ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Literature Review ◽  
Outcome Measures ◽  
Interest Group ◽  
Special Interest ◽  
Working Group ◽  
Qualitative Studies ◽  
Special Interest Group ◽  
The Core ◽  
Core Set

Objective.The current Juvenile Idiopathic Arthritis (JIA) Core Set was developed in 1997 to identify the outcome measures to be used in JIA clinical trials using statistical and consensus-based techniques, but without patient involvement. The importance of patient/parent input into the research process has increasingly been recognized over the years. An Outcome Measures in Rheumatology (OMERACT) JIA Core Set Working Group was formed to determine whether the outcome domains of the current core set are relevant to those involved or whether the core set domains should be revised.Methods.Twenty-four people from the United States, Canada, Australia, and Europe, including patient partners, formed the working group. Guided by the OMERACT Filter 2.0 process, we performed (1) a systematic literature review of outcome domains, (2) a Web-based survey (142 patients, 343 parents), (3) an idea-generation study (120 parents), (4) 4 online discussion boards (24 patients, 20 parents), and (5) a Special Interest Group (SIG) activity at the OMERACT 13 (2016) meeting.Results.A MEDLINE search of outcome domains used in studies of JIA yielded 5956 citations, of which 729 citations underwent full-text review, and identified additional domains to those included in the current JIA Core Set. Qualitative studies on the effect of JIA identified multiple additional domains, including pain and participation. Twenty-one participants in the SIG achieved consensus on the need to revise the entire JIA Core Set.Conclusion.The results of qualitative studies and literature review support the need to expand the JIA Core Set, considering, among other things, additional patient/parent-centered outcomes, clinical data, and imaging data.

scholarly journals e-INEBRIA Special Interest Group Roadmap for Best Practices for Research on Brief Digital Interventions for Problematic Alcohol and Illicit Drug Use

10.2196/20368 ◽  
2020 ◽  
Vol 22 (8) ◽  
pp. e20368
Author(s):  
Michael Patrick Schaub ◽  
Anne H Berman ◽  
Hugo López Pelayo ◽  
Nikolaos Boumparis ◽  
Zarnie Khadjesari ◽  
...  
Keyword(s):  
Drug Use ◽  
Interest Group ◽  
Special Interest ◽  
Illicit Drug ◽  
Illicit Drug Use ◽  
Special Interest Group ◽  
Brief Interventions ◽  
Future Research ◽  
Digital Interventions ◽  
Starting Point

There is great potential for scaling up the delivery of brief interventions for alcohol and illicit drug use, given the increasing coverage of mobile devices and technologies for digital interventions, including apps for smartphones and tablets. However, while the number of digital interventions is increasing rapidly, the involvement of brief-intervention researchers and the development of good practices has just begun. In 2018, the Special Interest Group on digital interventions of the International Network on Brief Interventions for Alcohol & Other Drugs (e-INEBRIA SIG) initiated a conversation regarding possible avenues of future research, which subsequently became a roadmap for digital interventions. This roadmap consists of points considered relevant for future research, ongoing technological developments, and their implementation across a continuum of prevention and care. Moreover, it outlines starting points for the diversification of brief digital interventions, as well as next steps for quality improvement and implementation in public health and clinical practice. The roadmap of the e-INEBRIA SIG on digital interventions is a starting point that indicates relevant next steps and provides orientation for researchers and interested practitioners with regard to the ambiguous literature and the complexity of current digital interventions.

scholarly journals Evolutionary psychiatry: a new College special interest group

2016 ◽  
Vol 40 (5) ◽  
pp. 233-236 ◽  
Author(s):  
Riadh Abed ◽  
Paul St John-Smith
Keyword(s):  
Interest Group ◽  
Royal College ◽  
Special Interest ◽  
Special Interest Group ◽  
Theory And Practice ◽  
Evolutionary Approach ◽  
Future Research ◽  
Evolutionary Science ◽  
Evolutionary Psychiatry

SummaryEvolutionary science remains an overlooked area in psychiatry and medicine. The newly established Royal College of Psychiatrists' Evolutionary Psychiatry Special Interest Group aims to reverse this trend by raising the profile of evolutionary thinking among College members and others further afield. Here we provide a brief outline of the importance of the evolutionary approach to both the theory and practice of psychiatry and for future research.

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