scholarly journals Hypolipidemic Activity of Methanolic Extract of Terminalia arjuna Leaves in Hyperlipidemic Rat Models

2011 ◽  
Vol 5 (3) ◽  
pp. 172-175
Author(s):  
D. Bala Sunder Reddy ◽  
P. Ravi Kumar ◽  
K. Bharavi ◽  
U. Venkateswa
Keyword(s):  
Methanolic Extract ◽  
Hypolipidemic Activity ◽  
Terminalia Arjuna ◽  
Rat Models

BRONCHODILATOR, CARDIOTONIC AND SPASMOLYTIC ACTIVITIES OF THE STEM BARKS OF TERMINALIA ARJUNA

2011 ◽  
Vol 1 ◽  
pp. 104-120
Author(s):  
Janbaz k ◽  
Keyword(s):  
Methanolic Extract ◽  
Terminalia Arjuna ◽  
In Vitro Experiments ◽  
Traditional System ◽  
Cardiovascular Systems

Terminalia arjuna, Roxb barks has a folkloric repute to possess spasmolytic, bronchodilator and cardiotonic, properties. The present study was undertaken to evaluate possible effects of methanolic extract of barks of Terminalia arjuna (Ta.Cr) in gastrointestinal, respiratory and cardiovascular systems via in vitro experiments to rationalize its use in traditional system of medicine.

scholarly journals Antihyperglycemic and hypolipidemic activity of methanolic extract of Amaranthus viridis leaves in experimental diabetes

2011 ◽  
Vol 43 (4) ◽  
pp. 450 ◽  
Author(s):  
Kuruba Lakshman ◽  
PullaUdaya Chandrika ◽  
Krishnamurthy Girija ◽  
Nagaraj Pruthvi
Keyword(s):  
Methanolic Extract ◽  
Experimental Diabetes ◽  
Hypolipidemic Activity

scholarly journals Screening of Different Leaf Extracts of Cassia fistula Linn for Investigation of Hypolipidemic Activity in Two Different Rat Models

2014 ◽  
Vol 30 ◽  
pp. 30-43
Author(s):  
Guruprasad V. Sutar ◽  
Kuntal Das ◽  
John Wilking Einstein
Keyword(s):  
Choline Chloride ◽  
Density Lipoprotein ◽  
Atherogenic Diet ◽  
Hypolipidemic Activity ◽  
Dependent Manner ◽  
Cassia Fistula ◽  
Leaf Extracts ◽  
Standard Drug ◽  
Rat Models ◽  
Dose Dependent

The present investigation was carried out to evaluate the hypolipidemic activity of methanolic and aqueous leaf extracts of Cassia fistula (CF) Linn (Family: Fabaceae) on atherogenic diet (2% cholesterol, 1% Choline Chloride and 2% Lard) induced Male Sprauge-Dawley rats for the period of 21 days. The rats receiving the treatment with leaf methanol and aqueous extract of CF showed significant (P < 0.001) reduction in total cholesterol (TC), triglycerides (TG), High density lipoprotein (HDL), lipid peroxidation (LPO) and other parameters at dose dependent manner but the effect was less than the standard drug Atorvastatin. The results revealed the effectiveness of CF plant against hyperlipidemic activity.

scholarly journals Terminalia arjuna Leaf Gall: The Possible Treatment for Sickle Cell Anaemia

2021 ◽  
pp. 64-75
Author(s):  
Ankita Singh ◽  
Payal Lodha ◽  
Archna Sharma
Keyword(s):  
Gas Chromatography ◽  
Sickle Cell ◽  
Mass Spectroscopy ◽  
Crude Extract ◽  
Methanolic Extract ◽  
Terminalia Arjuna ◽  
Active Compounds ◽  
Ms Analysis ◽  
Gas Chromatography Mass Spectroscopy ◽  
Insect Attack

Objective: To check the presence of various secondary metabolites produced in the plant under study Terminalia arjuna (Roxb.) Wight and Arn. post insect attack and gall formation. Study Design: Terminalia arjuna (Roxb.) Wight and Arn, a well known plant involved in treating heart ailments in the Ayurvedic system of medicine for centuries. The plant’s astringent bark exhibits cardioprotective properties and is commonly used in the treatment of hypertension, angina and coronary artery disease. T. arjuna plant suffers from gall development in its leaves due to the attack of an hemipteran insect Trioza fletcheri minor. Insect attack acts as a stress stimulus for the plant to produce various bio-active compounds as a part of their defence mechanism. The present study was intended for the identification of various compounds present in the crude extract obtained from the healthy and galled leaves of Terminalia arjuna. Place and Duration of Study: Experiments performed in the Plant pathology and tissue culture laboratory, Department of Botany University of Rajasthan, Jaipur, between April 2018 to March 2019. Methodology: Various methods are employed for the identification of possible bio-active compounds present in the plant crude extract, GC-MS (Gas Chromatography- Mass Spectroscopy) is one such method. To check the presence of phytochemicals produced post insect attack and infection in T. arjuna normal and galled leaves, Gas Chromatography-Mass Spectroscopy (GC-MS) of the methanolic extract was conducted. The normal healthy leaves and the galled leaves were collected, shade dried, pulverized and then soxhlet extracted for GC-MS analysis. Results: GC-MS analysis of methanolic extract of Terminalia arjuna leaves and galls confess the presence of 57 compounds in the gall extract while 21 compounds in normal (uninfected) leaf extract. The gall extract revealed the presence of various novel and medicinally important bio-active compounds, one of them was 5-Hydroxy Methyl Furfural (5-HMF).  Conclusion: 5-HMF, an aromatic aldehyde is an economically important chemical compound and well-known for its wide application in various fields. It is an efficient anti-sickling agent and has undergone pre-clinical testing as a potential treatment for the fatal sickle cell disease. Qualitative phytochemical screening revealed the presence of various bio-active compounds both in leaf and gall methanolic extract of Terminalia arjuna, thus proving the plant’s pharmaceutical importance. This study result will make a way for further research in plant’s pharmacological research.

scholarly journals Biological activity of Terminalia arjuna on Human Pathogenic Microorganisms

2016 ◽  
Vol 2 (1) ◽  
pp. 23 ◽  
Author(s):  
Tariq Javed ◽  
Sana Riaz ◽  
Muhammad Uzair ◽  
Gulam Mustafa ◽  
Ayesha Mohyuddin ◽  
...  
Keyword(s):  
Brine Shrimp ◽  
Methanolic Extract ◽  
Terminalia Arjuna ◽  
Pathogenic Microorganisms ◽  
Fruit Extract ◽  
Antifungal Effect ◽  
Phytotoxic Activity ◽  
Good Antibacterial Activity ◽  
Traditional Medicinal Plants ◽  
Phytotoxic Effect

World’s population relies chiefly on traditional medicinal plants, using their extracts or active constituents. Terminalia arjuna of family Combretaceae reported to be effective as aphrodisiac, expectorant, tonic, styptic, antidysenteric, sweet, acrid, purgative, laxative, astringent, diuretic, astringent, cirrhosis, cardioprotective and cancer treatment.   In present study, antibacterial, antifungal, brine shrimp lethality and phytotoxic effect of Terminalia arjuna was performed. Our results showed that methanolic extract of Terminalia arjuna leaves has moderate antifungal effect against Microsporm canis and fruit extract possess good antibacterial activity against Staphylococus aureus  and  Preudomonas aeroginosa. Moreover, Dichloromethane extract of Terminalia arjuna bark and fruit posses moderate phytotoxic activity. 

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