scholarly journals Successful Management of Pan-Resistant Acinetobacter baumannii Meningitis without Intrathecal or Intraventricular Antibiotic Therapy in a Neonate

2021 ◽  
Vol 53 (1) ◽  
pp. 146
Author(s):  
Shirin Sayyahfar ◽  
Farhad Abolhasan Choobdar ◽  
Mahdi Mashayekhi ◽  
Faramarz Masjedian Jazi
Keyword(s):  
Antibiotic Therapy ◽  
Acinetobacter Baumannii ◽  
Successful Management

scholarly journals Osteomyelitis: A Literature Review

2019 ◽  
Vol 11 (2) ◽  
pp. 69
Author(s):  
Rangga Rawung ◽  
Chita Moningkey
Keyword(s):  
Literature Review ◽  
Antibiotic Therapy ◽  
Basic Principle ◽  
Treatment Strategy ◽  
Operative Techniques ◽  
Successful Management ◽  
Anatomy And Physiology ◽  
Joint Infections ◽  
Basic Understanding

Abstrak: Infeksi pada tulang dan sendi masih merupakan kasus yang menantang. Kondisi ini memberikan banyak penyulit baik kepada dokter maupun pasien. Meski terapi antibiotika dilaporkan memberikan hasil yang memuaskan pada banyak kasus infeksi, tidak demikian pada kasus infeksi tulang dan sendi. Hal ini berhubungan dengan struktur anatomi dan fisiologi dari tulang. Diperlukan sebuah strategi tata laksana yang baik untuk mencapai hasil yang optimal. Prinsip dasar yang utama dalam mencapai pengobatan yang optimal ialah penegakan diagnosis awal yang tepat, termasuk di dalamnya proses investigasi pemeriksaan mikrobiologi dan patologi. Diperlukan pengertian dasar serta pengenalan kembali anatomi, fisiologi, patofisiologi, dan tata laksana terkini tentang osteomielitis untuk mencapai tatalaksana yang optimal.Kata kunci: diagnosis dan tata laksana osteomielitisAbstract: Infection in bone and joint is still a challenging case. It gives a lot of problems and frustration to the physician and patient. The successful antibiotic therapy in most infectious diseases is abortive to achieve in bone and joint infections because the different characteristic in anatomy and physiology of these structures. Therefore, treatment strategy, including non operative and operative techniques is required to deal with such conditions. The basic principle to achieve a successful management of osteomyelitis in general is correct initial diagnosis including investigation for microbiological and pathological examinations to allow the proper and long term lasting therapy of antibiotic. For that reason, it is required to have the basic understanding in dealing with this issue, obvious and updated. It is commited to review the pathophysiology, the diagnosis, and the management of osteomyelitis in order to presents basic facilities in dealing with osteomyelitis.Keywords: osteomyelitis diagnosis and management

Successful surgical management of infected modified Blalock-Taussig shunts

2004 ◽  
Vol 14 (2) ◽  
pp. 219-221
Author(s):  
Yoshio Ootaki ◽  
Masahiro Yamaguchi ◽  
Naoki Yoshimura
Keyword(s):  
Antibiotic Therapy ◽  
Surgical Management ◽  
Successful Management

We describe the successful management of two patients with infected modified Blalock-Taussig shunts by replacement of the graft combined with antibiotic therapy.

scholarly journals Successful management of mummified fetus in a heifer by prostaglandin therapy and episiotomy

2015 ◽  
Vol 5 (2) ◽  
Author(s):  
Gopal Krishan
Keyword(s):  
Single Dose ◽  
Antibiotic Therapy ◽  
Prostaglandin F2α ◽  
Successful Management ◽  
Uterine Infection ◽  
Holstein Friesian

Fetal mummification is one of the gestation- al accidents that occur due to intra-uterine death of fetus commonly at fourth, fifth and six months of gestation. This report describes the successful management of the mummified fetus in a five year old graded Holstein Friesian heifer cow using single dose of prostaglandin F2α analogue and by performing episiotomy. Antibiotic therapy was given to avoid any uterine infection.

scholarly journals 523. Dual vs. Triple Antibiotic Therapy for Carbapenem-Resistant Acinetobacter baumannii Infections

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S252-S252
Author(s):  
Justin Patrick Markelwith ◽  
Nikunj M Vyas ◽  
Mark Condoluci ◽  
Sungwook Kim
Keyword(s):  
Combination Therapy ◽  
Serum Creatinine ◽  
Antibiotic Therapy ◽  
Acinetobacter Baumannii ◽  
Clinical Cure ◽  
Group Analysis ◽  
Elevated Serum ◽  
Positive Association ◽  
Primary Analysis ◽  
Carbapenem Resistant

Abstract Background Infections caused by carbapenem-resistant Acinetobacter baumannii (CRAB) remain some of the most difficult to treat due to extremely high rates of resistance. The purpose of this study was to compare the efficacy of dual vs. triple targeted antibiotic regimens for CRAB infections. Methods This was an IRB approved retrospective cohort study performed at a 607-bed community health system between January 2016 and December 2018. Patients were included in the analysis if they were ≥18 years old and received antibiotics for CRAB for ≥72 hours. Patients were excluded if they were pregnant and had CRAB isolated solely from the urine. The primary endpoints of the study were differences in all-cause in-hospital mortality (ACIM) and clinical cure (CC) rates for patients treated with dual vs. triple antibiotic therapy. The secondary endpoint result focused on the difference in length of stay (LOS) between treatment groups. A sub-group analysis was performed for patients treated with tigecycline vs. minocycline combination therapy to determine differences ACIM and CC, and LOS. A multi-logistic regression analysis (MLRA) was performed to determine patient factors that were associated with ACIM and CC. Results A total of 32 patients were included in the primary analysis. No difference was seen in ACIM between dual vs. triple antibiotic groups (9.5% vs. 18.2%, P = 0.59). CC (63.6% vs. 57.1%, P = 1.0) and LOS (12 vs. 11 days, P = 1.0) was similar amongst patients treated with dual vs. triple antibiotic group. No differences were seen in ACIM (15.4% vs. 16.7% P = 1.0), CC (83.3% vs. 69.2%, P = 1.0) and LOS (15 vs. 14 days, P = 1.0) between tigecycline and minocycline combination therapy groups. The MLRA revealed a positive association with increased serum creatinine and ACIM (OR 3.29, 95% CI 1.35–8.04; P = 0.009) as well as shorter time to appropriate antibiotic therapy and clinical cure (OR 1.49, 95% CI 1.02–2.20; P = 0.04). CRAB isolates were more likely to be susceptible to minocycline vs. tigecycline (83% vs. 18%, P = 0.003). Conclusion No differences were seen in ACIM, CC and LOS between dual vs. triple antibiotic groups. Minocycline tends to sustain better susceptibility toward CRAB vs. tigecycline. Elevated serum creatinine was found to be a predictor for ACIM while shorter time to appropriate antibiotic therapy was associated with CC. Disclosures All authors: No reported disclosures.

Do Results of Surveillance Cultures Impact the Choice of Empirical Antibiotics Among Patients with Carbapenem-Resistant Acinetobacter baumannii Infections?

2015 ◽  
Vol 36 (12) ◽  
pp. 1455-1457
Author(s):  
Rossana Rosa ◽  
Jose Castro ◽  
Rachel Latibeaudiere ◽  
Nicholas Namias ◽  
L. Silvia Munoz-Price
Keyword(s):  
Antibiotic Therapy ◽  
Acinetobacter Baumannii ◽  
Infect Control Hosp ◽  
Empirical Antibiotic Therapy ◽  
Carbapenem Resistant ◽  
Surveillance Cultures ◽  
Empirical Antibiotics

We aimed to determine whether the results of surveillance cultures were associated with use of appropriate empirical antibiotic therapy among patients with carbapenem-resistant Acinetobacter baumannii infections. We found that surveillance status was not associated with appropriate empirical antibiotic therapy (P=.36). There were significant delays to concordant therapy among surveillance-positive patients (P=.03).Infect. Control Hosp. Epidemiol. 2015;36(12):1455–1457

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