scholarly journals Boronic acid functionalized polymers and hydrogels for biomedical applications

2011 ◽  
Author(s):  
M. Piest
Keyword(s):  
Boronic Acid ◽  
Biomedical Applications ◽  
Functionalized Polymers

scholarly journals Biomedical applications of boronic acid polymers

Polymer ◽  
2011 ◽  
Vol 52 (21) ◽  
pp. 4631-4643 ◽  
Author(s):  
Jennifer N. Cambre ◽  
Brent S. Sumerlin
Keyword(s):  
Boronic Acid ◽  
Biomedical Applications

scholarly journals Injectable dynamic covalent hydrogels of boronic acid polymers cross-linked by bioactive plant-derived polyphenols

2018 ◽  
Vol 6 (9) ◽  
pp. 2487-2495 ◽  
Author(s):  
Zhuojun Huang ◽  
Peyman Delparastan ◽  
Patrick Burch ◽  
Jing Cheng ◽  
Yi Cao ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Polyphenolic Compounds ◽  
Functionalized Polymers ◽  
Covalent Bonds ◽  
Cross Linker ◽  
And Function

Wisdom from nature: Plant-derived polyphenolic compounds can crosslink boronic acid functionalized polymers through formation of dynamic covalent bonds and function as both cross-linker and bioactive cargo.

A facile and general approach for the preparation of boronic acid-functionalized magnetic nanoparticles for the selective enrichment of glycoproteins

The Analyst ◽  
2019 ◽  
Vol 144 (2) ◽  
pp. 641-648 ◽  
Author(s):  
Xiaoting Xue ◽  
Rui Lu ◽  
Min Liu ◽  
Yi Li ◽  
Jiansheng Li ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Boronic Acid ◽  
Biomedical Applications ◽  
Clinical Diagnostics ◽  
Selective Enrichment ◽  
Functionalized Magnetic Nanoparticles

Biomedical applications and biomarkers for early clinical diagnostics and the treatment of diseases demand efficient and selective enrichment platforms for glycoproteins.

scholarly journals Multifunctional Polymeric Nanogels for Biomedical Applications

Gels ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. 228
Author(s):  
Tisana Kaewruethai ◽  
Chavee Laomeephol ◽  
Yue Pan ◽  
Jittima Amie Luckanagul
Keyword(s):  
Drug Delivery ◽  
Delivery System ◽  
Shell Structure ◽  
Biomedical Applications ◽  
Colloidal Stability ◽  
Functionalized Polymers ◽  
Core Shell ◽  
Structural Components ◽  
Bioactive Substances ◽  
Core Shell Structure

Currently, research in nanoparticles as a drug delivery system has broadened to include their use as a delivery system for bioactive substances and a diagnostic or theranostic system. Nanogels, nanoparticles containing a high amount of water, have gained attention due to their advantages of colloidal stability, core-shell structure, and adjustable structural components. These advantages provide the potential to design and fabricate multifunctional nanosystems for various biomedical applications. Modified or functionalized polymers and some metals are components that markedly enhance the features of the nanogels, such as tunable amphiphilicity, biocompatibility, stimuli-responsiveness, or sensing moieties, leading to specificity, stability, and tracking abilities. Here, we review the diverse designs of core-shell structure nanogels along with studies on the fabrication and demonstration of the responsiveness of nanogels to different stimuli, temperature, pH, reductive environment, or radiation. Furthermore, additional biomedical applications are presented to illustrate the versatility of the nanogels.

Responsive laminarin-boronic acid self-healing hydrogels for biomedical applications

2020 ◽  
Vol 52 (8) ◽  
pp. 997-1006 ◽  
Author(s):  
Adérito J. R. Amaral ◽  
Vítor M. Gaspar ◽  
João F. Mano
Keyword(s):  
Boronic Acid ◽  
Biomedical Applications ◽  
Self Healing

scholarly journals Boronic-Acid-Modified Nanomaterials for Biomedical Applications

ACS Omega ◽  
2021 ◽  
Author(s):  
Yu-Yu Aung ◽  
Alfinda Novi Kristanti ◽  
Hwei Voon Lee ◽  
Mochamad Zakki Fahmi
Keyword(s):  
Boronic Acid ◽  
Biomedical Applications

scholarly journals Boronic acid recognition of non-interacting carbohydrates for biomedical applications: increasing fluorescence signals of minimally interacting aldoses and sucralose

2017 ◽  
Vol 15 (45) ◽  
pp. 9727-9733 ◽  
Author(s):  
Angel Resendez ◽  
Md Abdul Halim ◽  
Jasmeet Singh ◽  
Dominic-Luc Webb ◽  
Bakthan Singaram
Keyword(s):  
Chemical Modification ◽  
Boronic Acid ◽  
Biomedical Applications ◽  
Binding Affinities ◽  
Detection Systems

To address carbohydrates that are commonly used in biomedical applications with low binding affinities for boronic acid based detection systems, two chemical modification methods were utilized to increase sensitivity.

scholarly journals Functionalized Biodegradable Polymers via Termination of Ring-Opening Polymerization by Acyl Chlorides

Polymers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 868
Author(s):  
Ilya Nifant’ev ◽  
Andrey Shlyakhtin ◽  
Vladimir Bagrov ◽  
Evgeny Shaputkin ◽  
Alexander Tavtorkin ◽  
...  
Keyword(s):  
Ring Opening ◽  
Biomedical Applications ◽  
Aqueous Media ◽  
Polymeric Materials ◽  
Ester Group ◽  
Ring Opening Polymerization ◽  
Functionalized Polymers ◽  
Aliphatic Polyesters ◽  
Acyl Chlorides ◽  
High Yields

Aliphatic polyesters are an important class of polymeric materials for biomedical applications due to their versatile and tunable chemistry, biocompatibility and biodegradability. A capability of direct bonding with biomedically significant molecules, provided by the presence of the reactive end functional groups (FGs), is highly desirable for prospective polymers. Among FGs, N-hydroxysuccinimidyl activated ester group (NHS) and maleimide fragment (MI) provide efficient covalent bonding with –NH– and –SH containing compounds. In our study, we found that NHS- and MI-derived acyl chlorides efficiently terminate living ring-opening polymerization of ε-caprolactone, L-lactide, ethyl ethylene phosphonate and ethyl ethylene phosphate, catalyzed by 2,6-di-tert-butyl-4-methylphenoxy magnesium complex, with a formation of NHS- and MI-functionalized polymers at a high yields. Reactivity of these polymers towards amine- and thiol-containing model substrates in organic and aqueous media was also studied.

Applications of Scanning Microscopy in Biomedical Research

1968 ◽  
Vol 26 ◽  
pp. 354-355
Author(s):  
T. L. Hayes
Keyword(s):  
Information Content ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
Dental Enamel ◽  
Resolving Power ◽  
Whole Mount ◽  
Two Parameters ◽  
Content Information ◽  
Sectioned Tissue

Biomedical applications of the scanning electron microscope (SEM) have increased in number quite rapidly over the last several years. Studies have been made of cells, whole mount tissue, sectioned tissue, particles, human chromosomes, microorganisms, dental enamel and skeletal material. Many of the advantages of using this instrument for such investigations come from its ability to produce images that are high in information content. Information about the chemical make-up of the specimen, its electrical properties and its three dimensional architecture all may be represented in such images. Since the biological system is distinctive in its chemistry and often spatially scaled to the resolving power of the SEM, these images are particularly useful in biomedical research.In any form of microscopy there are two parameters that together determine the usefulness of the image. One parameter is the size of the volume being studied or resolving power of the instrument and the other is the amount of information about this volume that is displayed in the image. Both parameters are important in describing the performance of a microscope. The light microscope image, for example, is rich in information content (chemical, spatial, living specimen, etc.) but is very limited in resolving power.

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