Impact of Probiotics in Human Health and Disease Treatment

2019 ◽  
pp. 35-67
Author(s):  
Jagan Mohan Rao Tingirikari ◽  
Muthu Vijaya Sarathy ◽  
Ashok Kumar Karthigarani
Keyword(s):  
Side Effects ◽  
Human Health ◽  
Pathogenic Bacteria ◽  
Microbial Population ◽  
Symbiotic Association ◽  
Disease Treatment ◽  
Treatment And Prevention ◽  
Health Promoting ◽  
Health And Disease

Probiotics have become the major breakthrough in therapeutic applications due to their various health promoting effects in humans by maintaining the homeostasis of the intestine and prevent microbial imbalance (dysbiosis) without any side effects. Dysbiosis in the microbial population is the major cause for several diseases in humans. Treatment of diseases using antibiotics is not recommended due to high cost, side effects, and the loss of intestinal friendly bacteria. Probiotics work in symbiotic association with the intestine and produce several metabolites which not only regulate the growth of pathogenic bacteria but also provide vital nutrients which contribute to human health. The present chapter highlights about the role of probiotics in treatment and prevention of different human diseases.

scholarly journals Mitochondrial Iron in Human Health and Disease

2019 ◽  
Vol 81 (1) ◽  
pp. 453-482 ◽  
Author(s):  
Diane M. Ward ◽  
Suzanne M. Cloonan
Keyword(s):  
Human Health ◽  
Mammalian Cells ◽  
Molecular Mechanisms ◽  
Innate Immune ◽  
Biological Functions ◽  
Mitochondrial Homeostasis ◽  
Innate Immune Signaling ◽  
Mitochondrial Iron ◽  
Health And Disease

Mitochondria are an iconic distinguishing feature of eukaryotic cells. Mitochondria encompass an active organellar network that fuses, divides, and directs a myriad of vital biological functions, including energy metabolism, cell death regulation, and innate immune signaling in different tissues. Another crucial and often underappreciated function of these dynamic organelles is their central role in the metabolism of the most abundant and biologically versatile transition metals in mammalian cells, iron. In recent years, cellular and animal models of mitochondrial iron dysfunction have provided vital information in identifying new proteins that have elucidated the pathways involved in mitochondrial homeostasis and iron metabolism. Specific signatures of mitochondrial iron dysregulation that are associated with disease pathogenesis and/or progression are becoming increasingly important. Understanding the molecular mechanisms regulating mitochondrial iron pathways will help better define the role of this important metal in mitochondrial function and in human health and disease.

Role of alpha-1 antitrypsin in human health and disease

2014 ◽  
Vol 276 (4) ◽  
pp. 311-335 ◽  
Author(s):  
F. de Serres ◽  
I. Blanco
Keyword(s):  
Human Health ◽  
Health And Disease ◽  
Alpha 1 Antitrypsin

scholarly journals Dietary Bioactive Compounds and Human Health and Disease

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 348 ◽  
Author(s):  
Sonia González
Keyword(s):  
Human Health ◽  
Bioactive Compounds ◽  
Scientific Evidence ◽  
Health And Disease ◽  
Nutritional Compounds ◽  
Dietary Bioactive Compounds

In the last century, solid scientific evidence has demonstrated the role of nutritional compounds in the maintenance of health [...]

The role of Galactose in human health and disease

Open Medicine ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. 409-419 ◽  
Author(s):  
Muhammad Manwar Hussain ◽  
Mukhtarul Hassan ◽  
Noor Shaik ◽  
Zeeshan Iqbal
Keyword(s):  
Human Health ◽  
Cellular Signaling ◽  
Biological Processes ◽  
Microbial Adhesion ◽  
Wide Range ◽  
Health And Disease ◽  
Stereochemical Properties ◽  
Specific Sugar

AbstractAccording to the universal biological findings, cellular bodies are covered with an intense coating of glycans. Diversity of glycan chains, linked to lipids and proteins is due to isomeric and conformational modifications of various sugar residues, giving rise to unique carbohydrate structures with a wide range of sequences and anomeric configurations. Proteins and lipids, carrying specific sugar residues (like Galactose) with particular stereochemical properties (sequence, anomery and linkages) are involved in broad spectrums of biological processes, including intercellular and intracellular interactions, microbial adhesion and cellular signaling. By studying the role of specific seterochemical features of galactose (Gal), we have improved our understanding about the normal physiology and diseases in human bodies.

Multifunctional role of fucoidan, sulfated polysaccharides in human health and disease: A journey under the sea in pursuit of potent therapeutic agents

2020 ◽  
Vol 164 ◽  
pp. 4263-4278 ◽  
Author(s):  
Biswajita Pradhan ◽  
Srimanta Patra ◽  
Rabindra Nayak ◽  
Chhandashree Behera ◽  
Soumya Ranjan Dash ◽  
...  
Keyword(s):  
Human Health ◽  
Therapeutic Agents ◽  
Sulfated Polysaccharides ◽  
Health And Disease
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