Gamification

2021 ◽  
pp. 293-319
Author(s):  
Diogo Machado ◽  
Rui Carvalho ◽  
Pedro Brandão
Keyword(s):  
Chronic Disease ◽  
Diabetes Management ◽  
Type I Diabetes ◽  
Acceptance Rate ◽  
Type I ◽  
Current Version ◽  
Second Stage ◽  
Two Stages ◽  
Made In

Diabetes is a chronic disease requiring a strict management. MyDiabetes is a mobile application for type I diabetes management that, as other mHealth applications, faces the challenge of user adherence and motivation. Here the authors describe the application's redesign and the implementation of different gamification techniques to tackle these challenges. The transition to the current version of the application was made in two stages. The first addressed the redesign of the application and started implementing gamification techniques. The second stage improved some of the features and added others. After the second stage, a new survey was conducted to evaluate the implemented features and improvements. While objectives and incentives to increase the number of records were endorsed by 56.5% of users, health directed badges and objectives increased the acceptance rate to 91.3%. Long-term effectiveness of the gamification approach will be done in the future.

Effects of long-term optimization and short-term deterioration of glycemic control on glucose counterregulation in type I diabetes mellitus

Diabetes ◽  
1984 ◽  
Vol 33 (4) ◽  
pp. 394-400 ◽  
Author(s):  
G. Bolli ◽  
P. De Feo ◽  
S. De Cosmo ◽  
G. Perriello ◽  
G. Angeletti ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Type I Diabetes ◽  
Type I Diabetes Mellitus ◽  
Type I ◽  
Short Term

scholarly journals Tolerance and pancreatic islet transplantation

2001 ◽  
Vol 356 (1409) ◽  
pp. 759-765 ◽  
Author(s):  
Luca Inverardi ◽  
Camillo Ricordi
Keyword(s):  
Diabetes Mellitus ◽  
Islet Transplantation ◽  
Type I Diabetes ◽  
Immunological Tolerance ◽  
Type I Diabetes Mellitus ◽  
Current Status ◽  
Type I ◽  
Pancreatic Islet Transplantation ◽  
Term Survival

Islet transplantation holds renewed promise as a cure for type I diabetes mellitus. Results of recent clinical trials have shown remarkable success, and have reignited universal optimism for this procedure. In spite of this success, the need for life–long immunosuppression of the recipient still limits islet transplantation to patients with poorly controlled diabetes or to those requiring kidney transplantation. It is obvious that the achievement of immunological tolerance would broaden the indication for islet transplantation to a much larger cohort of patients with type I diabetes mellitus, most likely preventing long–term complications and contributing to a much improved quality of life. Increased understanding of the basic mechanisms of tolerance induction has resulted in the implementation of numerous experimental approaches to achieve long–term survival of islet grafts in the absence of chronic immunosuppression. In this brief review we will attempt to summarize the current status of research and knowledge.

scholarly journals An Improved Progressive TIN Densification Filtering Method Considering the Density and Standard Variance of Point Clouds

2018 ◽  
Vol 7 (10) ◽  
pp. 409 ◽  
Author(s):  
Youqiang Dong ◽  
Ximin Cui ◽  
Li Zhang ◽  
Haibin Ai
Keyword(s):  
Point Clouds ◽  
High Density ◽  
Type I ◽  
Densification Process ◽  
Type I Errors ◽  
Second Stage ◽  
Standard Variance ◽  
Triangular Irregular Network ◽  
Two Stages ◽  
Type Ii Errors

The progressive TIN (triangular irregular network) densification (PTD) filter algorithm is widely used for filtering point clouds. In the PTD algorithm, the iterative densification parameters become smaller over the entire process of filtering. This leads to the performance—especially the type I errors of the PTD algorithm—being poor for point clouds with high density and standard variance. Hence, an improved PTD filtering algorithm for point clouds with high density and variance is proposed in this paper. This improved PTD method divides the iterative densification process into two stages. In the first stage, the iterative densification process of the PTD algorithm is used, and the two densification parameters become smaller. When the density of points belonging to the TIN is higher than a certain value (in this paper, we define this density as the standard variance intervention density), the iterative densification process moves into the second stage. In the second stage, a new iterative densification strategy based on multi-scales is proposed, and the angle threshold becomes larger. The experimental results show that the improved PTD algorithm can effectively reduce the type I errors and total errors of the DIM point clouds by 7.53% and 4.09%, respectively, compared with the PTD algorithm. Although the type II errors increase slightly in our improved method, the wrongly added objective points have little effect on the accuracy of the generated DSM. In short, our improved PTD method perfects the classical PTD method and offers a better solution for filtering point clouds with high density and standard variance.

scholarly journals Cost Effectual Distributed Cooperative Cluster based Communication Protocol in Wireless Sensor Network

2020 ◽  
Vol 8 (6) ◽  
pp. 5652-5656
Keyword(s):  
Communication Protocol ◽  
Wireless Sensor ◽  
Team Leaders ◽  
Great Strength ◽  
Second Stage ◽  
Remote Sensor ◽  
Channel Distortion ◽  
Two Stages ◽  
Intense Research

Theoretical energy recognition in remote sensor systems has received intense research interest in the late years. Radio variation, channel distortion, and blockage bring great strength and responsiveness to packets broadcast over a remote channel. A twin innovation is effective communication that can drastically increase the channel range and reduce transmission vigor consumption in disrupting channel. Growth in the direct range brings with it a reduced fault rate. In this paper, an acceptable correspondence method is proposed for each tab with active sending and receiving clusters. It consists of two stages, the precise routing phase, the selective and transmitting stage. In the routing phase, the basic route between the source and the sink hub is started. In the second stage, centers of fundamental development toward flattering team leaders select additional touch centers with minimal biomass costs from their surroundings, and then spread from bundle to cluster to the recently established endurance cluster. Reductions in error rate and regeneration are proven by the fact that malpractice funds become long-term obligation systems.

scholarly journals Paediatric Type1 Diabetes Management and Mothers’ Emotional Intelligence Interactions

2021 ◽  
Author(s):  
Jolanta Žilinskienė ◽  
Linas Šumskas ◽  
Dalia Antinienė
Keyword(s):  
Emotional Intelligence ◽  
Disease Management ◽  
Diabetes Management ◽  
Type I Diabetes ◽  
Negative Emotions ◽  
Haemoglobin A1c ◽  
Type I ◽  
Type1 Diabetes ◽  
Demographic Questionnaire ◽  
And Control

The functioning of the parents’ emotional sphere is very important to a child’s mental and physical health. This study focused on investigating the association between mothers’ emotional intelligence (EI) and paediatric type I diabetes (T1DM) disease management in their children. We hypothesized that mothers’ EI is associated with T1DM outcomes. Mothers of children with T1DM aged 6-12 years were surveyed. One hundred and thirty-four mothers, the main caregivers of their diabetic children, provided measures of EI and completed a demographic questionnaire. The primary indicator of diabetes management was haemoglobin A1c (HbA1c; the main form of glycosylated haemoglobin). EI scales and subscales were associated with glycaemic management indices. Logistic regression analysis was applied for the assessment of the association between parents’ EI and their paediatric with T1DM disease management. The analysis demonstrated a statistically significant correlation between T1DM management and mothers’ ability to understand and control own emotions, to transform their own negative emotions into positive and to control own negative emotions. Mothers’ EI scales and subscales of understanding and regulating their own emotions, subscales of transforming their own negative emotions into positive ones and controlling their own negative emotions were statistically reliable predictors of glycaemic control in children with T1DM.

Towards a Renewed Vision of Imperial Authority

2019 ◽  
pp. 237-269
Author(s):  
Florin Leonte
Keyword(s):  
Fourteenth Century ◽  
Political Communication ◽  
The West ◽  
Substantial Body ◽  
Political Messages ◽  
Imperial Authority ◽  
Second Stage ◽  
Two Stages

The chapter discusses how Manuel Palaiologos’ texts reveal not only the emperor’s standpoints in his attempts to answer political challenges, but also a long-term imperial project that sought to establish a system of effective political communication by exhibiting his fatherly concern for his son and co-emperor. This project involved two stages with changing approaches. In the first stage, the emperor strengthened his connections with the literati and frequently chaired theatra. The letters and the dialogic mode of his text on marriage point to the fact that during the last decade of the fourteenth century, the emperor did not have at his disposal too many possibilities of circulating his political messages except for the rather informal meetings in the framework of theatra. In a second stage, which chronologically coincided with the years following the emperor’s return from the West, Manuel attempted to consolidate his ruling position by highlighting in the Foundations and the Orations that he appointed his son, John, as successor. In the absence of a more substantial body of court rhetoricians, the emperor undertook the role of a social-political commentator and accordingly put forward a personal discourse on imperial authority.

scholarly journals No Evidence of Viral Transmission following Long-Term Implantation of Agarose Encapsulated Porcine Islets in Diabetic Dogs

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Lawrence S. Gazda ◽  
Horatiu V. Vinerean ◽  
Melissa A. Laramore ◽  
Richard D. Hall ◽  
Joseph W. Carraway ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type I Diabetes ◽  
Viral Transmission ◽  
Type I Diabetes Mellitus ◽  
Type I ◽  
Safe Procedure ◽  
C Peptide ◽  
Porcine Islets ◽  
Diabetic Dogs

We have previously described the use of a double coated agarose-agarose porcine islet macrobead for the treatment of type I diabetes mellitus. In the current study, the long-term viral safety of macrobead implantation into pancreatectomized diabetic dogs treated with pravastatin (n=3) was assessed while 2 dogs served as nonimplanted controls. A more gradual return to preimplant insulin requirements occurred after a 2nd implant procedure (days 148, 189, and >652) when compared to a first macrobead implantation (days 9, 21, and 21) in all macrobead implanted animals. In all three implanted dogs, porcine C-peptide was detected in the blood for at least 10 days following the first implant and for at least 26 days following the second implant. C-peptide was also present in the peritoneal fluid of all three implanted dogs at 6 months after 2nd implant and in 2 of 3 dogs at necropsy. Prescreening results of islet macrobeads and culture media prior to transplantation were negative for 13 viruses. No evidence of PERV or other viral transmission was found throughout the study. This study demonstrates that the long-term (2.4 years) implantation of agarose-agarose encapsulated porcine islets is a safe procedure in a large animal model of type I diabetes mellitus.

Plasma endothelin-1 and total insulin exposure in diabetes mellitus

1999 ◽  
Vol 97 (2) ◽  
pp. 149-156 ◽  
Author(s):  
Flemming WOLLESEN ◽  
Lars BERGLUND ◽  
Christian BERNE
Keyword(s):  
Type Ii Diabetes ◽  
Type I Diabetes ◽  
Insulin Dose ◽  
Albumin Excretion Rate ◽  
Wall Structure ◽  
Type I ◽  
Type Ii ◽  
C Peptide ◽  
Patients With Diabetes

Insulin stimulates endothelin-1 (ET-1) expression in a dose-response relationship, and ET-1 effects on vascular wall structure are similar to the long-term complications of diabetes. We therefore determined whether the plasma ET-1 concentration in patients with diabetes is associated with their total insulin exposure to see if plasma ET-1 might be a link between insulin exposure and long-term complications of diabetes. We studied 69 patients with Type I and 40 patients with Type II diabetes mellitus in equally tight glycaemic control for 2 years in a cross-sectional design. We measured basal and glucagon-stimulated plasma C-peptide, abdominal sagittal diameter, skinfold thickness, glomerular filtration rate, albumin excretion rate and standard clinical characteristics. Mean HbA1c was 6.4% in Type I and 6.3% in Type II diabetes. Patients with an albumin excretion rate > 300 μg/min were excluded. Adjusted mean plasma ET-1 was 4.11 (S.E.M. 0.39) pg/ml in 21 normal subjects, 3.47 (0.19) pg/ml in Type I diabetes and 4.84 (0.26) pg/ml in Type II diabetes (P = 0.0001). In all patients with measurable plasma C-peptide, plasma ET-1 was associated with basal plasma C-peptide (r = 0.5018, P < 0.0001), with stimulated plasma C-peptide (r = 0.5379, P < 0.0001), and with total daily insulin dose (r = 0.2219, P = 0.00851). Abdominal obesity, metabolic abnormalities, blood pressure and glomerular filtration rate were not associated with plasma ET-1, when corrected for C-peptide and daily insulin dose. Our study shows that the plasma concentration of ET-1 is closely associated with insulin secretion and insulin dose in patients with diabetes. Plasma ET-1 is higher in Type II diabetes than in Type I diabetes. Increased insulin exposure in patients with diabetes may have long-term effects on vascular wall structure through its stimulation of ET-1 expression.

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