Symptomatology and Clinical Features of Human COVID-19

2022 ◽  
pp. 28-57
Author(s):  
Mohamed Echchakery ◽  
Souad El Mouahid ◽  
Soraia El Baz ◽  
Maryam Mountassir ◽  
Ahmed Taoufik Hakkoum ◽  
...  

Severe Acute Respiratory Syndrome Virus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which was identified at the end of December 2019 in China. Symptoms of COVID-19 can appear after an incubation phase of the virus of 2 to 14 days, the most common being fever, cough, and asthenia. Other specific symptoms may include shortness of breath or difficulty breathing, muscle pain, sore throat, chills, loss of smell or sensation, chest pain, headache, nausea, rash, diarrhea, and vomiting. The severity of these symptoms can be mild or even extreme causing serious damage to several organs, directly and indirectly, namely pulmonary, renal, hepatic, cardiac, digestive, neurological. Some people have only mild symptoms, while others are asymptomatic. Seniors or those at risk for certain chronic diseases, such as massive obesity, diabetes, heart disease, lung disease, kidney disease, immune system abnormalities, and liver disease are more susceptible to COVID-19 and can develop more serious and fatal complications.

2017 ◽  
Vol 56 (206) ◽  
Author(s):  
Deepshikha Gaire ◽  
Santosh Sharma ◽  
Kumar Poudel ◽  
Pankaj Pant

Paragonimiasis is a zoonosis caused by many species of Paragonimus commonly P. westermani. Human get infected by eating raw, salted, pickled, smoked, partially cooked crustaceans (crayfish or crabs). Clinical manifestations ranges from non-specific symptoms like pain abdomen, diarrhea, urticarial rashes, fever to pleuropulmonary symptoms like cough, hemoptysis, chest pain and dyspnea. 48 yrs, female presented at TUTH emergency with fever on and off for 9 months, cough and shortness of breath for 3 months, lethargy, malaise and urticaria with history of raw crab intake one month prior to the onset of symptoms. Blood and pleural fluid analysis revealed raised total counts with eosinophilia and x-ray showed bilateral infiltration of lower lobes with pleural effusion. Diagnosis was confirmed by microscopic examination of sputum for Paragonimus. She responded well to Praziquantel. Pulmonary paragonimiasis must be considered in the differential diagnosis of unresolving pneumonia and unexplained hypereosinophilia.  [PubMed]


2000 ◽  
Vol 9 (4) ◽  
pp. 237-244 ◽  
Author(s):  
SB Richards ◽  
M Funk ◽  
KA Milner

BACKGROUND: Mortality rates for coronary heart disease are higher in blacks than in whites. OBJECTIVES: To examine differences between blacks and whites in the manifestation of symptoms of coronary heart disease and in delay in seeking treatment. METHODS: Patients were directly observed as they came to an emergency department with symptoms suggestive of coronary heart disease. The sample included 40 blacks and 191 whites with a final diagnosis of angina or acute myocardial infarction. RESULTS: After controlling for pertinent demographic and clinical characteristics, logistic regression analysis revealed that blacks were more likely than whites to have shortness of breath (odds ratio = 3.16; 95% CI = 1.49-6.71; P = .003) and left-sided chest pain (odds ratio = 2.55; 95% CI = 1.10-5.91; P =.03). Blacks delayed a mean of 26.8 hours (SD = 30.3; median = 11 hours), whereas whites delayed a mean of 24.4 hours (SD = 41.7; median = 5 hours) in seeking care. Mean delay time was not significantly different for blacks and whites; differences in median delay time were of borderline significance (P = .05). CONCLUSIONS: Blacks were more likely than whites to have shortness of breath and left-sided chest pain as the presenting symptoms of coronary heart disease. Differences in delay in seeking treatment were not significant, although blacks tended to delay longer than did whites. The relatively small number of blacks may account for the lack of observed racial differences in both initial symptoms and in delay in seeking treatment.


2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
S T Thodeti ◽  
D S L Lattanzio ◽  
D D Drenic ◽  
T M K Kuraan ◽  
M U K Khalid ◽  
...  

Abstract Introduction Intuitively, severity of symptoms usually correlates with severity of disease process or disease progression. In this regard, the ACC Sports and Exercise Cardiology Section proposed an algorithm for competitive athletes to assess and manage cardiac injury after COVID-19 infection based on initial symptoms. However, there are no published, evidence-based data to substantiate this approach. Purpose This study was designed to assess the correlation between symptoms at the time of initial diagnosis to post-COVID recovery cardiac symptoms and findings on a cardiac MRI study (CMR). It is hypothesized that the initial symptoms at the time of a positive COVID-19 test may not be reliable or sufficient in predicting the severity of post-COVID recovery symptoms or findings on CMR. Methods An institutional cardiac imaging database was queried for all patients with a positive COVID-19 PCR test, who subsequently underwent a CMR for post-COVID recovery cardiac symptoms. Severity of COVID-19 symptoms were assessed using a checklist of mild symptoms and more severe symptoms as defined by the Centers for Disease Control, Atlanta GA. Mild symptoms included: fever/chills, cough, fatigue, body aches, headache, loss of taste/smell, sore throat, congestion, and nausea vomiting diarrhea. More severe symptoms included: shortness of breath, chest pain, and confusion. For each patient, prevalence of these symptoms was assessed at the time of initial diagnosis, and then again post-COVID recovery, just prior to the time of CMR. Inflammatory heart disease (IHD) was defined as pericarditis and/or myocarditis using the recently modified Lake Louise criteria, including T1 and T2 relaxation mapping. Results 58 patients with a positive COVID-19 PCR test were identified, who subsequently underwent a CMR study for evaluation of cardiac symptoms. 36 patients (62%) had no symptoms at the time of initial diagnosis, while 7 patients (12%) had mild symptoms. Lastly, 15 patients (26%) had more severe symptoms at the time of initial diagnosis. All CMR studies were prompted by the subsequent development of shortness of breath or chest pain. Detection rates of IHD in these 3 groups of patients is delineated in Figure 1. A chi-squared test was used to assess any statistically significant differences in the CMR detection rate of IHD based on initial symptoms. There was no significant difference in the likelihood of IHD based on initial COVID symptoms (p-value=0.856). Conclusion Forty-three of 58 patients (74%) with no/mild symptoms at the time of initial COVID-19 diagnosis developed more severe post-COVID symptoms requiring CMR. In contrast, 15 of 58 patients (26%) with more severe symptoms at the time of initial COVID-19 diagnosis had persistence of these symptoms requiring CMR. These data suggest that the severity of symptoms on initial presentation with COVID-19 does not predict post-COVID recovery symptoms or CMR findings of inflammatory heart disease. FUNDunding Acknowledgement Type of funding sources: None.


2021 ◽  
Vol 6 (3) ◽  

All women face the threat of heart disease. Knowing the symptoms and risks unique to women, as well as eating a hearthealthy diet and exercising, can help protect you. Heart disease is often thought to be more of a problem for men. However, it’s the most common cause of death for both women and men in the United States. Because some heart disease symptoms in women can differ f Heart attack symptoms for women. The most common heart attack symptom in women is the same as in men some type of chest pain, pressure or discomfort that lasts more than a few minutes or comes and goes. But chest pain is not always severe or even the most noticeable symptom, particularly in women. Women often describe it as pressure or tightness. And, it’s possible to have a heart attack without chest pain. Women are more likely than men to have heart attack symptoms unrelated to chest pain, such as: Neck, jaw, shoulder, upper back or abdominal discomfort, Shortness of breath, Pain in one or both arms, Nausea or vomiting, Sweating, Lightheadedness or dizziness, unusual fatigue, Indigestion. These symptoms may be vague and not as noticeable as the crushing chest pain often associated with heart attacks. This might be because women tend to have blockages not only in their main arteries but also in the smaller ones that supply blood to the heart-a condition called small vessel heart disease or coronary microvascular disease. Women tend to have symptoms more often when resting, or even when asleep, than they do in men. Emotional stress can play a role in triggering heart attack symptoms in women. Because women don’t always recognize their symptoms as those of a heart attack, they tend to show up in emergency rooms after heart damage has occurred. Also, because their symptoms often differ from men’s, women might be diagnosed less often with heart disease than men are. If you have symptoms of a heart attack or think you’re having one, call for emergency medical help immediately. Don’t drive yourself to the emergency room unless you have no other options. Rom those in men, women often don’t know what to look for


EDIS ◽  
2020 ◽  
Vol 2020 (5) ◽  
Author(s):  
Daniela Rivero-Mendoza ◽  
Wendy J. Dahl

Inflammation is your body's response to injury and infection—it's how your immune system helps to protect you from harm. In contrast, chronic inflammation contributes to many diseases, including heart disease, diabetes, and kidney and liver disease. This new 4-page publication of the UF/IFAS Food Science and Human Nutrition Department discusses inflammation and the dietary choices that may help to reduce chronic inflammation. Written by Daniela Rivero-Mendoza and Wendy Dahl.https://edis.ifas.ufl.edu/fs402


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 259-261
Author(s):  
Aamir Khan ◽  
Rajni K. Gurmule

Vasavaleha is one of the best medicine given for respiratory diseases. Corona viruses typically affect the respiratory system, causing symptoms such as coughing, fever and shortness of breath. It also affects host immune system of human body. Spreading rate of this disease is very high. Whole world is seeking for the treatment which can uproots this diseases. There in no vaccine available till date against this pandemic disease. Ayurveda mainly focuses on prevention of diseases alongwith its total cure. Rajyakshma Vyadhi is MadhyamMarga Roga as per Ayurveda. It shows many symptoms such as Kasa, Shwasa etc. By overall view of Covid 19, shows its resemblance with Rajyakshma Vyadhi described in Ayurveda. Vasavaleha is a Kalpa which is described in Rogadhikara of Rajyakshma. It shows Kasahara, Shwashara properties. It consists of Vasa, Pipalli, Madhu and Goghrita. These components shows actions like bronchodilation, antitussive effect and many more other actions. Pipalli shows important Rasayana effect. So in present review, we have tried to focus on role of Vasavaleha in the management of Covid 19. This can be used as preventive as well as adjuvant medication in treating Covid 19. There is need of further clinical research to rule of exact action of Vasavaleha against Covid 19.


CHEST Journal ◽  
2021 ◽  
Vol 159 (1) ◽  
pp. e35-e38
Author(s):  
John Odackal ◽  
Tijana Milinic ◽  
Tim Amass ◽  
Edward D. Chan ◽  
Jeremy Hua ◽  
...  

1999 ◽  
Vol 14 (3) ◽  
pp. 67-72 ◽  
Author(s):  
John R. Richards ◽  
Stephen J. Ferrall

AbstractStudy objective:To determine the ability of emergency medical services (EMS) providers to subjectively triage patients with respect to hospital admission and to determine patient characteristics associated with increased likelihood of admission.Methods:A prospective, cross-sectional study of a consecutive sample of patients arriving by ambulance during the month of February 1997 at an urban, university hospital, Emergency Department. Emergency medical services providers completed a questionnaire asking them to predict admission to the hospital and requested patient demographic information. Predictions were compared to actual patient disposition.Results:A total of 887 patients were included in the study, and 315 were admitted to the hospital (36%). With respect to admission, emergency medical services providers had an accuracy rate of 79%, with a sensitivity of 72% and specificity of 83% (kappa = 0.56). Blunt traumatic injury and altered mental status were the most common medical reasons for admission. Variables significantly associated with high admission rates were patients with age > 50 years, chest pain or cardiac complaints, shortness of breath or respiratory complaints, Medicare insurance, and Hispanic ethnicity. The emergency medical services providers most accurately predicted admission for patients presenting with labor (kappa = 1.0), shortness of breath / respiratory complaints (kappa = 0.84), and chest pain (kappa = 0.77).Conclusion:Emergency medical services providers can predict final patient disposition with reasonable accuracy, especially for patients presenting with labor, shortness of breath, or chest pain. Certain patient characteristics are associated with a higher rate of actual admission.


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