Comparison of Machine Learning Algorithms in Predicting the COVID-19 Outbreak

2022 ◽  
pp. 320-336
Author(s):  
Asiye Bilgili

Health informatics is an interdisciplinary field in the computer and health sciences. Health informatics, which enables the effective use of medical information, has the potential to reduce both the cost and the burden of healthcare workers during the pandemic process. Using the machine learning algorithms support vector machines, naive bayes, k-nearest neighbor, and C4.5 algorithms, a model performance evaluation was performed to identify the algorithm that will show the highest performance for the prediction of the disease. Three separate training and test datasets were created 70% - 30%, 75% - 25%, and 80% - 20%, respectively. The implementation phase of the study was carried out by following the CRISP-DM steps, and the analyses were made using the R language. By examining the model performance evaluation criteria, the findings show that the C4.5 algorithm showed the best performance with 70% training dataset.

2015 ◽  
Vol 32 (6) ◽  
pp. 821-827 ◽  
Author(s):  
Enrique Audain ◽  
Yassel Ramos ◽  
Henning Hermjakob ◽  
Darren R. Flower ◽  
Yasset Perez-Riverol

Abstract Motivation: In any macromolecular polyprotic system—for example protein, DNA or RNA—the isoelectric point—commonly referred to as the pI—can be defined as the point of singularity in a titration curve, corresponding to the solution pH value at which the net overall surface charge—and thus the electrophoretic mobility—of the ampholyte sums to zero. Different modern analytical biochemistry and proteomics methods depend on the isoelectric point as a principal feature for protein and peptide characterization. Protein separation by isoelectric point is a critical part of 2-D gel electrophoresis, a key precursor of proteomics, where discrete spots can be digested in-gel, and proteins subsequently identified by analytical mass spectrometry. Peptide fractionation according to their pI is also widely used in current proteomics sample preparation procedures previous to the LC-MS/MS analysis. Therefore accurate theoretical prediction of pI would expedite such analysis. While such pI calculation is widely used, it remains largely untested, motivating our efforts to benchmark pI prediction methods. Results: Using data from the database PIP-DB and one publically available dataset as our reference gold standard, we have undertaken the benchmarking of pI calculation methods. We find that methods vary in their accuracy and are highly sensitive to the choice of basis set. The machine-learning algorithms, especially the SVM-based algorithm, showed a superior performance when studying peptide mixtures. In general, learning-based pI prediction methods (such as Cofactor, SVM and Branca) require a large training dataset and their resulting performance will strongly depend of the quality of that data. In contrast with Iterative methods, machine-learning algorithms have the advantage of being able to add new features to improve the accuracy of prediction. Contact: [email protected] Availability and Implementation: The software and data are freely available at https://github.com/ypriverol/pIR. Supplementary information: Supplementary data are available at Bioinformatics online.


2021 ◽  
Vol 4 (3) ◽  
pp. 251524592110268
Author(s):  
Roberta Rocca ◽  
Tal Yarkoni

Consensus on standards for evaluating models and theories is an integral part of every science. Nonetheless, in psychology, relatively little focus has been placed on defining reliable communal metrics to assess model performance. Evaluation practices are often idiosyncratic and are affected by a number of shortcomings (e.g., failure to assess models’ ability to generalize to unseen data) that make it difficult to discriminate between good and bad models. Drawing inspiration from fields such as machine learning and statistical genetics, we argue in favor of introducing common benchmarks as a means of overcoming the lack of reliable model evaluation criteria currently observed in psychology. We discuss a number of principles benchmarks should satisfy to achieve maximal utility, identify concrete steps the community could take to promote the development of such benchmarks, and address a number of potential pitfalls and concerns that may arise in the course of implementation. We argue that reaching consensus on common evaluation benchmarks will foster cumulative progress in psychology and encourage researchers to place heavier emphasis on the practical utility of scientific models.


2021 ◽  
Vol 34 (01) ◽  
Author(s):  
Hemalatha S ◽  
◽  
Nivedha S ◽  
Dr. M Sangeetha ◽  
Dr. K. E Kannammal ◽  
...  

Cancers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3817
Author(s):  
Shi-Jer Lou ◽  
Ming-Feng Hou ◽  
Hong-Tai Chang ◽  
Chong-Chi Chiu ◽  
Hao-Hsien Lee ◽  
...  

No studies have discussed machine learning algorithms to predict recurrence within 10 years after breast cancer surgery. This study purposed to compare the accuracy of forecasting models to predict recurrence within 10 years after breast cancer surgery and to identify significant predictors of recurrence. Registry data for breast cancer surgery patients were allocated to a training dataset (n = 798) for model development, a testing dataset (n = 171) for internal validation, and a validating dataset (n = 171) for external validation. Global sensitivity analysis was then performed to evaluate the significance of the selected predictors. Demographic characteristics, clinical characteristics, quality of care, and preoperative quality of life were significantly associated with recurrence within 10 years after breast cancer surgery (p < 0.05). Artificial neural networks had the highest prediction performance indices. Additionally, the surgeon volume was the best predictor of recurrence within 10 years after breast cancer surgery, followed by hospital volume and tumor stage. Accurate recurrence within 10 years prediction by machine learning algorithms may improve precision in managing patients after breast cancer surgery and improve understanding of risk factors for recurrence within 10 years after breast cancer surgery.


2020 ◽  
Vol 1500 ◽  
pp. 012131
Author(s):  
Firdaus ◽  
Andre Herviant Juliano ◽  
Naufal Rachmatullah ◽  
Sarifah Putri Rafflesia ◽  
Dinna Yunika Hardiyanti ◽  
...  

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