The impact of Negative to Positive Training Dataset Ratio on Atrial Fibrillation Classification Machine Learning Algorithms Performance

2020 ◽  
Vol 1500 ◽  
pp. 012131
Author(s):  
Firdaus ◽  
Andre Herviant Juliano ◽  
Naufal Rachmatullah ◽  
Sarifah Putri Rafflesia ◽  
Dinna Yunika Hardiyanti ◽  
...  
Keyword(s):  
Machine Learning ◽  
Atrial Fibrillation ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Training Dataset ◽  
The Impact

scholarly journals Homology-based prediction of resistance to antituberculous medications using machine learning algorithms

2019 ◽  
Author(s):  
Mohamed Dafaalla ◽  
Mohamed Omer Elsadiq Abdullah ◽  
Sahar Bakhiet ◽  
Muntasir Ibrahim
Keyword(s):  
Machine Learning ◽  
Drug Resistance ◽  
Predictive Value ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Training Dataset ◽  
Solid Base ◽  
K Nearest Neighbors ◽  
Linear Discriminant ◽  
The Impact

Abstract Objectives: We aimed to develop a prediction model based on machine learning algortihms to predict the impact of variants on resistance of Mycobacterium. Data was collected from TB Drug Resistance Database (TBDReaMDB), and the drug sensitive variants from GMTV database. We also collected a List of 1115 NsSNPS reported in proteins related to drug resistance to Rifampicin, Isoniazid, Pyrazinamide and Ethambutol. PMUT online tool was used to generate the features included in the algorithm training. We trained different classifiers using R software on the features generated by PMUT. The classifiers trained are Random Forrest, Boosting prediction, Naive Bayes, Neural networks, k-Nearest Neighbors, Logistic regression, and Linear Discriminant analysis.Results: The 445 variants valid for comparison were divided into training dataset (75%) and testing dataset (25%). We compared the classifiers according to the AUC, accuracy, kappa, sensitivity, specificity, positive predictive value, and negative predictive value. Results show that random forrest is the best classifier (accuracy: 0.9072. Kappa: 0.690, Sensitivity: 1.00, Specificity : 0.5909, Pos-Pred Value : 0.8929, Neg-Pred Value : 1.00, Detection Rate : 0.773). This indicates that Homology-based machine learning algorithms could be a solid base for development of rapid tools for screening of M.TB resistance to medications.

Forecasting US movies box office performances in Turkey using machine learning algorithms

2020 ◽  
Vol 39 (5) ◽  
pp. 6579-6590
Author(s):  
Sandy Çağlıyor ◽  
Başar Öztayşi ◽  
Selime Sezgin
Keyword(s):  
Machine Learning ◽  
Global Economy ◽  
Learning Algorithms ◽  
Forecast Model ◽  
Machine Learning Algorithms ◽  
Gradient Boosting ◽  
High Stakes ◽  
Box Office ◽  
Industry Forecast ◽  
The Impact

The motion picture industry is one of the largest industries worldwide and has significant importance in the global economy. Considering the high stakes and high risks in the industry, forecast models and decision support systems are gaining importance. Several attempts have been made to estimate the theatrical performance of a movie before or at the early stages of its release. Nevertheless, these models are mostly used for predicting domestic performances and the industry still struggles to predict box office performances in overseas markets. In this study, the aim is to design a forecast model using different machine learning algorithms to estimate the theatrical success of US movies in Turkey. From various sources, a dataset of 1559 movies is constructed. Firstly, independent variables are grouped as pre-release, distributor type, and international distribution based on their characteristic. The number of attendances is discretized into three classes. Four popular machine learning algorithms, artificial neural networks, decision tree regression and gradient boosting tree and random forest are employed, and the impact of each group is observed by compared by the performance models. Then the number of target classes is increased into five and eight and results are compared with the previously developed models in the literature.

scholarly journals Accurate estimation of isoelectric point of protein and peptide based on amino acid sequences

2015 ◽  
Vol 32 (6) ◽  
pp. 821-827 ◽  
Author(s):  
Enrique Audain ◽  
Yassel Ramos ◽  
Henning Hermjakob ◽  
Darren R. Flower ◽  
Yasset Perez-Riverol
Keyword(s):  
Machine Learning ◽  
Isoelectric Point ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Basis Set ◽  
Superior Performance ◽  
Supplementary Information ◽  
Training Dataset ◽  
Accurate Estimation ◽  
Prediction Methods

Abstract Motivation: In any macromolecular polyprotic system—for example protein, DNA or RNA—the isoelectric point—commonly referred to as the pI—can be defined as the point of singularity in a titration curve, corresponding to the solution pH value at which the net overall surface charge—and thus the electrophoretic mobility—of the ampholyte sums to zero. Different modern analytical biochemistry and proteomics methods depend on the isoelectric point as a principal feature for protein and peptide characterization. Protein separation by isoelectric point is a critical part of 2-D gel electrophoresis, a key precursor of proteomics, where discrete spots can be digested in-gel, and proteins subsequently identified by analytical mass spectrometry. Peptide fractionation according to their pI is also widely used in current proteomics sample preparation procedures previous to the LC-MS/MS analysis. Therefore accurate theoretical prediction of pI would expedite such analysis. While such pI calculation is widely used, it remains largely untested, motivating our efforts to benchmark pI prediction methods. Results: Using data from the database PIP-DB and one publically available dataset as our reference gold standard, we have undertaken the benchmarking of pI calculation methods. We find that methods vary in their accuracy and are highly sensitive to the choice of basis set. The machine-learning algorithms, especially the SVM-based algorithm, showed a superior performance when studying peptide mixtures. In general, learning-based pI prediction methods (such as Cofactor, SVM and Branca) require a large training dataset and their resulting performance will strongly depend of the quality of that data. In contrast with Iterative methods, machine-learning algorithms have the advantage of being able to add new features to improve the accuracy of prediction. Contact: [email protected] Availability and Implementation: The software and data are freely available at https://github.com/ypriverol/pIR. Supplementary information: Supplementary data are available at Bioinformatics online.

scholarly journals An analytical survey on the role of machine learning algorithms in case of intrusion detection

2020 ◽  
Vol 5 (19) ◽  
pp. 32-35
Author(s):  
Anand Vijay ◽  
Kailash Patidar ◽  
Manoj Yadav ◽  
Rishi Kushwah
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Intrusion Detection ◽  
Intrusion Detection System ◽  
Detection System ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Handling Mechanism ◽  
The Impact

In this paper an analytical survey on the role of machine learning algorithms in case of intrusion detection has been presented and discussed. This paper shows the analytical aspects in the development of efficient intrusion detection system (IDS). The related study for the development of this system has been presented in terms of computational methods. The discussed methods are data mining, artificial intelligence and machine learning. It has been discussed along with the attack parameters and attack types. This paper also elaborates the impact of different attack and handling mechanism based on the previous papers.

scholarly journals Teleconsultations between Patients and Healthcare Professionals in Primary Care in Catalonia: the Evaluation of Text Classification Algorithms Using Machine Learning

2019 ◽  
Author(s):  
Francesc López Seguí ◽  
Ricardo Ander Egg Aguilar ◽  
Gabriel de Maeztu ◽  
Anna García-Altés ◽  
Francesc García Cuyàs ◽  
...  
Keyword(s):  
Machine Learning ◽  
Primary Care ◽  
Text Classification ◽  
Learning Strategy ◽  
Care Service ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Face To Face ◽  
Classification Tool ◽  
The Impact

Background: the primary care service in Catalonia has operated an asynchronous teleconsulting service between GPs and patients since 2015 (eConsulta), which has generated some 500,000 messages. New developments in big data analysis tools, particularly those involving natural language, can be used to accurately and systematically evaluate the impact of the service. Objective: the study was intended to examine the predictive potential of eConsulta messages through different combinations of vector representation of text and machine learning algorithms and to evaluate their performance. Methodology: 20 machine learning algorithms (based on 5 types of algorithms and 4 text representation techniques)were trained using a sample of 3,559 messages (169,102 words) corresponding to 2,268 teleconsultations (1.57 messages per teleconsultation) in order to predict the three variables of interest (avoiding the need for a face-to-face visit, increased demand and type of use of the teleconsultation). The performance of the various combinations was measured in terms of precision, sensitivity, F-value and the ROC curve. Results: the best-trained algorithms are generally effective, proving themselves to be more robust when approximating the two binary variables "avoiding the need of a face-to-face visit" and "increased demand" (precision = 0.98 and 0.97, respectively) rather than the variable "type of query"(precision = 0.48). Conclusion: to the best of our knowledge, this study is the first to investigate a machine learning strategy for text classification using primary care teleconsultation datasets. The study illustrates the possible capacities of text analysis using artificial intelligence. The development of a robust text classification tool could be feasible by validating it with more data, making it potentially more useful for decision support for health professionals.

scholarly journals Machine Learning Algorithms to Predict Recurrence within 10 Years after Breast Cancer Surgery: A Prospective Cohort Study

Cancers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3817
Author(s):  
Shi-Jer Lou ◽  
Ming-Feng Hou ◽  
Hong-Tai Chang ◽  
Chong-Chi Chiu ◽  
Hao-Hsien Lee ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Machine Learning ◽  
Learning Algorithms ◽  
External Validation ◽  
Model Development ◽  
Cancer Surgery ◽  
Machine Learning Algorithms ◽  
Breast Cancer Surgery ◽  
Training Dataset

No studies have discussed machine learning algorithms to predict recurrence within 10 years after breast cancer surgery. This study purposed to compare the accuracy of forecasting models to predict recurrence within 10 years after breast cancer surgery and to identify significant predictors of recurrence. Registry data for breast cancer surgery patients were allocated to a training dataset (n = 798) for model development, a testing dataset (n = 171) for internal validation, and a validating dataset (n = 171) for external validation. Global sensitivity analysis was then performed to evaluate the significance of the selected predictors. Demographic characteristics, clinical characteristics, quality of care, and preoperative quality of life were significantly associated with recurrence within 10 years after breast cancer surgery (p < 0.05). Artificial neural networks had the highest prediction performance indices. Additionally, the surgeon volume was the best predictor of recurrence within 10 years after breast cancer surgery, followed by hospital volume and tumor stage. Accurate recurrence within 10 years prediction by machine learning algorithms may improve precision in managing patients after breast cancer surgery and improve understanding of risk factors for recurrence within 10 years after breast cancer surgery.

Comparison of Machine Learning Algorithms in the Interpolation and Extrapolation of Flame Describing Functions

2019 ◽  
Author(s):  
Michael McCartney ◽  
Matthias Haeringer ◽  
Wolfgang Polifke
Keyword(s):  
Machine Learning ◽  
Gaussian Processes ◽  
Spline Interpolation ◽  
Learning Algorithms ◽  
Predictive Performance ◽  
Machine Learning Algorithms ◽  
Test Time ◽  
Minimal Amount ◽  
Data Points ◽  
The Impact

Abstract This paper examines and compares commonly used Machine Learning algorithms in their performance in interpolation and extrapolation of FDFs, based on experimental and simulation data. Algorithm performance is evaluated by interpolating and extrapolating FDFs and then the impact of errors on the limit cycle amplitudes are evaluated using the xFDF framework. The best algorithms in interpolation and extrapolation were found to be the widely used cubic spline interpolation, as well as the Gaussian Processes regressor. The data itself was found to be an important factor in defining the predictive performance of a model, therefore a method of optimally selecting data points at test time using Gaussian Processes was demonstrated. The aim of this is to allow a minimal amount of data points to be collected while still providing enough information to model the FDF accurately. The extrapolation performance was shown to decay very quickly with distance from the domain and so emphasis should be put on selecting measurement points in order to expand the covered domain. Gaussian Processes also give an indication of confidence on its predictions and is used to carry out uncertainty quantification, in order to understand model sensitivities. This was demonstrated through application to the xFDF framework.

scholarly journals Predicting Alert Source Device using Machine Learning Algorithms

2020 ◽  
Vol 9 (9) ◽  
pp. 1-10
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Model Building ◽  
Learning Algorithm ◽  
Learning Algorithms ◽  
Research Work ◽  
Machine Learning Algorithms ◽  
Training Dataset ◽  
Imbalanced Dataset ◽  
Daunting Task

In a large distributed virtualized environment, predicting the alerting source from its text seems to be daunting task. This paper explores the option of using machine learning algorithm to solve this problem. Unfortunately, our training dataset is highly imbalanced. Where 96% of alerting data is reported by 24% of alerting sources. This is the expected dataset in any live distributed virtualized environment, where new version of device will have relatively less alert compared to older devices. Any classification effort with such imbalanced dataset present different set of challenges compared to binary classification. This type of skewed data distribution makes conventional machine learning less effective, especially while predicting the minority device type alerts. Our challenge is to build a robust model which can cope with this imbalanced dataset and achieves relative high level of prediction accuracy. This research work stared with traditional regression and classification algorithms using bag of words model. Then word2vec and doc2vec models are used to represent the words in vector formats, which preserve the sematic meaning of the sentence. With this alerting text with similar message will have same vector form representation. This vectorized alerting text is used with Logistic Regression for model building. This yields better accuracy, but the model is relatively complex and demand more computational resources. Finally, simple neural network is used for this multi-class text classification problem domain by using keras and tensorflow libraries. A simple two layered neural network yielded 99 % accuracy, even though our training dataset was not balanced. This paper goes through the qualitative evaluation of the different machine learning algorithms and their respective result. Finally, two layered deep learning algorithms is selected as final solution, since it takes relatively less resource and time with better accuracy values.

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