The Law of Conservation of Incidents in the Space of Nanoworld

Author(s):  
Gennadiy Vladimirovich Zhizhin

This article first establishes the existence of integral equality relatively to the issue of the transmission of information by elements of lower and higher dimensions in the polytopes of the higher dimension that describe natural objects in the nanoworld. This integral equality is called the law of conservation of incidents. There is the incidence interpreted as the transfer of information from one material body to another. The fulfillment of the law of conservation of incidents for the n - simplex of the n - golden - hyper - rhombohedron and the n - cross - polytope is proved in general terms. It is shown that the law of conservation of incidents is valid for both regular bodies and irregular bodies, which can be clusters of chemical compounds. The incident conservation law can serve as a mathematical basis for the recently discovered epigenetic principle of the transmission of hereditary information without changing the sequence of genes in DNA and RNA molecules.

This chapter first establishes the existence of integral equality in relation to the issue of the transmission of information by elements of lower and higher dimensions in the polytopes of higher dimension that describe natural objects. This integral equality is called the law of conservation of incidents. There is the incidence interpreted as the transfer of information from one material body to another. The fulfillment of the law of conservation of incidents for the n-simplex of the n-cube and the n-cross-polytope is proved in general terms. It is shown that the law of conservation of incidents is valid for both regular bodies and irregular bodies, which can be clusters of chemical compounds. The incident conservation law can serve as a mathematical basis for the recently discovered epigenetic principle of the transmission of hereditary information without changing the sequence of genes in DNA and RNA molecules.


For the first time it was established that for any convex polytope of higher dimension there is an integral equality in the transfer of information from low-dimensional elements to higher-dimensional elements and vice versa. This integral equality is called the law of conservation of incidents. In previous works of the author, this law was established for some polytopes of a particular kind. There is the incidence interpreted as the transfer of information from one material body to another. It is shown that the law of conservation of incidents is valid for both regular bodies and irregular bodies, which can be clusters of chemical compounds. The incident conservation law can serve as a mathematical basis for the recently discovered epigenetic principle of the transmission of hereditary information without changing the sequence of genes in DNA and RNA molecules.


2008 ◽  
Vol 13 (7) ◽  
pp. 581-590 ◽  
Author(s):  
Marta Maroto ◽  
Yolanda Fernandez ◽  
Juan Ortin ◽  
Fernando Pelaez ◽  
M. Angerles Cabello

The NS1 protein is a nonstructural protein encoded by the influenza A virus. It is responsible for many alterations produced in the cellular metabolism upon infection by the virus and for modulation of virus virulence. The NS1 protein is able to perform a large variety of functions due to its ability to bind various types of RNA molecules, from both viral and nonviral origin, and to interact with several cell factors. With the aim of exploring whether the binding of NS1 protein to viral RNA (vRNA) could constitute a novel target for the search of anti-influenza drugs, a filter-binding assay measuring the specific interaction between the recombinant His-NS1 protein from influenza A virus and a radiolabeled model vRNA ( 32P-vNSZ) was adapted to a format suitable for screening and easy automation. Flashplate® technology (PerkinElmer, Waltham, MA), either in 96- or 384-well plates, was used. The Flashplate® wells were precoated with the recombinant His-NS1 protein, and the binding of His-NS1 to a 35S-vNSZ probe was measured. A pilot screening of a collection of 27,520 mixtures of synthetic chemical compounds was run for inhibitors of NS1 binding to vRNA. We found 3 compounds in which the inhibition of NS1 binding to vRNA, observed at submicromolar concentrations, was correlated with a reduction of the cytopathic effect during the infection of cell cultures with influenza virus. These results support the hypothesis that the binding of NS1 to vRNA could be a novel target for the development of anti-influenza drugs. ( Journal of Biomolecular Screening 2008:581-590)


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Roberto Fernández-Villarino ◽  
J. Andrés Domínguez-Gómez

PurposeThis study aims to explore how responsible corporate behaviour, specifically self-imposed financial regulatory control, might subsequently be reflected in the financial performance of companies subject to such regulation.Design/methodology/approachIn this study, the authors aim to explore how financial compliance in the form of the Economic Control Regulation (ECR) has impacted on the financial performance of professional football clubs in Spain. To this purpose, the authors adopted a quasi-experimental before and after study design. This type of design assesses the object of study before and after a specific event in order to determine whether this event has had any effects on the object. In this case, the event was the coming into effect of the ECR in the fiscal year of 2012, and the object hypothetically affected was the clubs’ economic performance.FindingsThe authors can confirm that in general terms and for the whole set of clubs analysed, the ECR has had a strong and positive effect on financial performance.Research limitations/implicationsIn this study, the authors wish to establish a link between the idea of “compliance” and that of “responsible corporate management practice”. It is not just a matter of compliance with the law. The fact of complying with certain laws could, in general terms, or from the point of view of common sense, be qualified as “responsible behaviour”. However, under the contemporary concept of corporate responsibility, compliance with the law is a behaviour that must be taken for granted. Responsibility, therefore, would entail going beyond such expected behaviour to one that exceeds the environment's expectation of the corporate actor.Practical implicationsWhat extent improvements in financial performance have also boosted social performance. Confirming such a positive effect endorses the argument that ethical improvements in corporate culture have a general effect on business sustainability in its different aspects: economic, social, environmental and in governance.Social implicationsThe authors may foresee that the culture of compliance will spread from the finance departments to other management areas. Its connection with ethical business practice is directly linked to the more complex concept of the “citizen company”. There are suggest interesting bases on which professional football clubs might move from a traditional profit-oriented company model towards a more contemporary one oriented towards relationships of integrity with the sport's environment. This study shows that the ECR has been a starting point for the development of Spanish professional football clubs towards this type of “citizen company”.Originality/valueIt was a single-sector study whose principal value lies in the verification of whether responsible economic management (the main consequence of applying the ECR) had any effects on company profits, financial results and other important indicators. In addition to fostering responsibility, this new management model involves a special innovation, as it is based on self-regulation (i.e. on regulations not imposed by national or supranational states), designed and implemented to ensure the sector's viability.


2019 ◽  
pp. 136-150
Author(s):  
R. Chorniy

The article is devoted to the investigation of forms and types of guilt in the composition of crimes against the basics of national security of Ukraine. The presence of a number of unresolved issues at the theoretical and legal level on this issue actualizes the need for its scientific elaboration and formulation of proposals to improve the provisions of the law on criminal liability. The purpose of the article is to investigate the problematic issues of forms and types of guilt in crimes against the bases of national security of Ukraine, ways of fixing them in the articles of Section I of the Special part of the Criminal Code of Ukraine and to develop sound proposals for their solution based on the provisions of the doctrine of criminal law. The article presents the existing approaches of doctrinal interpretation by scientists of the provisions on wine, its forms and types, through which the research of this feature in the crimes under Art. Art. 109 - 114-1 of the Criminal Code of Ukraine. It is proved that the most reasonable is the psychological concept of guilt, which promotes the insertion of forms and types of guilt in crimes against the basics of national security with a formal composition, the elucidation of forms of guilt in the warehouses of crimes provided by articles of section I of the Special part of the Criminal Code of Ukraine, in which the legislator directly does not say that it is one of the preconditions for the proper qualification of the act committed by the person. It is proved that the basis for the conclusion about the intentional form of guilt is based on: 1) a direct indication of it in the norm of the law (Part 1 of Article 110 and Part 1 of Article 111 of the Criminal Code of Ukraine); 2) indication of the specific purpose or motives of the criminal behavior (Part 1 of Article 109, Note 1, Part 1 and Part 2 of Article 110-2, Article 113, Part 1 of Article 114 and Article 112 of the Criminal Code of Ukraine) ; 3) combination of the above mentioned features in one norm (Part 1 of Article 110 of the Criminal Code of Ukraine); 4) interpretation of terms used in the dispositions of certain articles and / or through the description in the law of the features of the crime (Part 1 of Article 110, Part 2 of Article 109, Part 1 of Article 110, Part 1 of Article 111, Article 112, Article 113, Part 1 of Article 114 and Part 1 of Article 114-1 of the Criminal Code of Ukraine); 5) interpretation of terms used in other articles of the Special (espionage as a part of state treason) or articles of the General part of the Criminal Code of Ukraine (conspiracy to commit the actions provided for in part 1 of Article 109 of the Criminal Code of Ukraine (Article 26 of the Criminal Code of Ukraine), attempted murder state or public figure (Article 112 of the Criminal Code of Ukraine) (part 1 of Article 15 of the Criminal Code of Ukraine); 6) the orientation of socially dangerous acts. The specifics of constructing all these norms testify to the direct intent of the person who committed the respective crime. On this basis it is substantiated that the lack of specification of intent in part 1 of Art. 111 and Part 1 of Art. 110 of the Criminal Code of Ukraine does not contribute to the clarity of the provisions of the Criminal Code in the specified part, and the direct intent in the composition of these crimes is evidenced by: 1) special purpose (Part 1 of Article 110 of the Criminal Code); 2) the terms used in the dispositions of the said articles (“violation of the order… established by the Constitution of Ukraine” (part 1 of Article 110), “transfer of information…, transition to the enemy's side, rendering… assistance in carrying out subversive activities against Ukraine”) ( Part 1 of Article 111); 3) the focus of socially dangerous action. In order to eliminate the ambiguous interpretation of the provisions of Part 1 of Art. 110 and Part 1 of Art. 111 of the Criminal Code it is proposed to amend them accordingly. The forms and type of guilt in the warehouses of crimes with material composition (Part 3 of Article 110, Part 3 and 4 of Article 110-2, Part 2 of Article 114-1 of the Criminal Code of Ukraine) were not clearly reflected in the relevant rules of the law. It is substantiated that the subject's attitude to socially dangerous consequences (deaths of people (h. 3 Art. 110, h. 2 Art. 114-1), other grave consequences (h. 3 Art. 110, h. 4 Art. 110- 2, Part 2 of Article 114-1) Causing considerable property damage (Part 3 of Article 110-2) can be intentional or negligent.


2021 ◽  
pp. 467-492
Author(s):  
Robert Merkin ◽  
Séverine Saintier ◽  
Jill Poole

Course-focused and comprehensive, Poole’s Textbook on Contract Law provides an accessible overview of the key areas on the law curriculum. In general terms non-performance constitutes a breach of contract. The contract may have expressly allocated the risk of certain external events which occur after the contract is made to one of the parties by means of a force majeure clause. The terms of this clause will determine the parties’ positions if the event in question occurs. In the absence of an express allocation of the risk, the frustration doctrine is a residual doctrine that governs when such frustrating events intervene, without the fault of either party. These frustrating events relate to impossibility, illegality or frustration of the common purpose of both parties. This chapter examines the legal basis of the frustration doctrine, when it applies, when it does not apply and the legal consequences of frustration on the parties’ positions. Frustration automatically terminates the contract for the future and, where it applies, the provisions of the Law Reform (Frustrated Contracts) Act 1943 govern the parties’ pre-existing legal position.


Author(s):  
Stefanella Boatto ◽  
David G. Dritschel ◽  
Rodrigo G. Schaefer

A major challenge for our understanding of the mathematical basis of particle dynamics is the formulation of N-body and N-vortex dynamics on Riemann surfaces. In this paper, we show how the two problems are, in fact, closely related when considering the role played by the intrinsic geometry of the surface. This enables a straightforward deduction of the dynamics of point masses, using recently derived results for point vortices on general closed differentiable surfaces M endowed with a metric g . We find, generally, that Kepler's Laws do not hold. What is more, even Newton's First Law (the law of inertia) fails on closed surfaces with variable curvature (e.g. the ellipsoid).


1986 ◽  
Vol 39 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Matthew Black

To speak, in general terms, of trends in modern biblical study is often to over-simplify; and certainly to claim that there has been, in recent years, a trend away from the traditional classicist or ‘hellenist’ approach to New Testament problems towards a more Hebraic or semitic-centred approach would be to be guilty of the same exaggeration as E. C. Hoskyns in 1930: ‘(There are) grounds for supposing no further progress in the understanding of … Christianity to be possible unless the ark of New Testament exegesis be recovered from its wanderings in the land of the Philistines (sic) and be led back not merely to Jerusalem, for that might mean contemporary Judaism, but to its home in the midst of the classical Old Testament Scriptures — to the Law and the Prophets.’ There is, nevertheless, some truth in A. M. Hunter's later statement: ‘After ransacking all sorts of sources, Jewish and Greek (and, we may add, starting all sorts of “hares”, some of which have not run very well), (scholars) are discovering the truth of Augustine's dictum, “The New Testament lies hidden in the Old, and the Old is made plain in the New”’ (Novum Testamentum in vetere latet, vetus in novo patet).


Author(s):  
Carlos Góómez-Jara Dííez

At the beginning of the twenty-first century two legal concepts linking citizen/enemy status with criminal law have provoked heated discussion both in Europe and in the United States. The American concept, i.e., Enemy Combatants, has been basically developed by the U.S. Supreme Court and more recently by the Bush administration. The European term, Feindstrafrecht/Enemy Criminal Law, has been fundamentally coined and explained by leading German academic Professor Güünther Jakobs. Though born and raised by different parents, the two concepts have numerous aspects in common, or at least this will be argued throughout the paper. The most important common ground is that both concepts, with similar terminology, try to address the problem of what to do with individuals who are viewed as sources of extreme dangerousness. Put differently, they both tackle the question of whether citizenship-in a broad sense-concedes certain rights but imposes a fundamental duty: to have a minimum of law-abiding behavior. If the duty is not fulfilled, then the rights are not acknowledged and the individual is treated as an enemy, not as a citizen. The underlying reasoning oozes social contract theory. This is not by chance, as great philosophers (Rousseau, Fichte, Hobbes, Kant) have employed similar arguments that are briefly sketched in the essay. There are also references to the legal theory behind the scenes predicating that in order for legal constructions to exist (rights, the State), they need to be followed by most people. Hence such a duty to comply, in general terms, with the law is imposed upon all persons. If not, law would be just daydreaming. Strong and consistent as all these arguments sound, the basic problem with this type of reasoning is that it is hard for the legal system to follow without entering into self-contradiction. In this light, criticism will be brought by one of the most prominent social theories of the time, i.e., systems theory, arguing that law-abiding behavior is a precondition for legal institutions to exist, yes, but it cannot be secured by law itself. It is a precondition that has to be presupposed by the legal system. Moreover, using this kind of necessity rule, i.e., the State and the Law need to secure the preconditions of their own existence (self-preservation), entails a diabolic logic as it may lead to the destruction of the system itself. To this extent, self-preservation against external threats (terrorist attacks) and internal threats (curtailment of civil liberties) seems equally important. The essay finishes with some proposals for resolving this delicate matter, trying to reflect a keen sense of balance and forward-looking thinking.


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