Prediction of chronic obstructive pulmonary disease stages using machine learning algorithms

2022 ◽  
Vol 14 (1) ◽  
pp. 0-0

Identifying chronic obstructive pulmonary disease (COPD) severity stages is of great importance to control the related mortality rates and reduce the associated costs. This study aims to build prediction models for COPD stages and, to compare the relative performance of five machine learning algorithms to determine the optimal prediction algorithm. This research is based on data collected from a private hospital in Egypt for the two calendar years 2018 and 2019. Five machine learning algorithms were used for the comparison. The F1 score, specificity, sensitivity, accuracy, positive predictive value and negative predictive value were the performance measures used for algorithms comparison. Analysis included 211 patients’ records. Our results show that the best performing algorithm in most of the disease stages is the PNN with the optimal prediction accuracy and hence it can be considered as a powerful prediction tool used by decision makers in predicting severity stages of COPD.

2021 ◽  
Vol 10 (4) ◽  
pp. 155-163
Author(s):  
Atefeh Goshvarpour ◽  
Ateke Goshvarpour

Background: Today, with the spread of tobacco use and increased environmental pollutions, respiratory diseases are considered important factors threatening human life. Chronic obstructive pulmonary disease (COPD) is a kind of inflammatory lung disease. Clinically, COPD is currently diagnosed and monitored by spirometry as the gold-standard technique although spirometry systems encounter some limitations. Thanks to the economical handling and sampling, practicality, and non-invasiveness of saliva biomarkers, it is promising for the testing environment. Accordingly, the current analytic observational study aimed to propose an intelligent system for COPD detection. Materials and Methods: To this end, 40 COPD (8 females and 32 males in the age range of 71.67±8.27 years) and 40 controls (17 females and 23 males within the age range of 38.23±14.05 years) were considered in this study. The samples were characterized by absolute minimum value and the average value of the real and imaginary parts of saliva permittivity. Additionally, the age, gender, and smoking status of the participants were determined, and then the performance of various classifiers was evaluated by adjusting k in k-fold cross-validation (CV) and classifier parameterization. Results: The results showed that the k-nearest neighbor outperformed other classifiers. Using both 8- and 10-fold CV, the maximum classification rates of 100% were achieved for all k values. On the other hand, increasing the k in k-fold CV improved classification performances. The positive role of parameterization was revealed as well. Conclusions: Overall, these findings authenticated the potential of machine learning (ML) algorithms in the diagnosis of COPD using subjects’ saliva features and demographic information.


PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0188532 ◽  
Author(s):  
Sumanth Swaminathan ◽  
Klajdi Qirko ◽  
Ted Smith ◽  
Ethan Corcoran ◽  
Nicholas G. Wysham ◽  
...  

2017 ◽  
Vol 25 (3) ◽  
pp. 811-827 ◽  
Author(s):  
Dimitris Spathis ◽  
Panayiotis Vlamos

This study examines the clinical decision support systems in healthcare, in particular about the prevention, diagnosis and treatment of respiratory diseases, such as Asthma and chronic obstructive pulmonary disease. The empirical pulmonology study of a representative sample (n = 132) attempts to identify the major factors that contribute to the diagnosis of these diseases. Machine learning results show that in chronic obstructive pulmonary disease’s case, Random Forest classifier outperforms other techniques with 97.7 per cent precision, while the most prominent attributes for diagnosis are smoking, forced expiratory volume 1, age and forced vital capacity. In asthma’s case, the best precision, 80.3 per cent, is achieved again with the Random Forest classifier, while the most prominent attribute is MEF2575.


Sign in / Sign up

Export Citation Format

Share Document