Optimization of Ultrasonic Extraction of Polyphenol from Pinus Koraiensis Bark Using Response Surface Methodology

2011 ◽  
Vol 183-185 ◽  
pp. 1874-1878 ◽  
Author(s):  
Ji Chang Wang ◽  
Zhen Yu Wang ◽  
Zi Luan Fan ◽  
Li Li Zuo ◽  
Shuang Qi Tian ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Phenolic Compounds ◽  
Response Surface ◽  
Ethanol Concentration ◽  
Processing Parameters ◽  
Ultrasonic Extraction ◽  
Raw Material ◽  
Extraction Time ◽  
Pinus Koraiensis ◽  
Ultrasonic Power

Ultrasonic technology was applied for phenolic compounds extraction from the Pinus koraiensis bark （PKB） and response surface methodology (RSM) was used to optimize the effects of processing parameters on phenolic compounds yields. When ultrasonic power 160W,three independent variables were ultrasonic extraction time (X1 20-40min), ratio of water to raw material (X2 1:20-1:40 g/mL)and ethanol concentration(X3 20％-60％), respectively.The optimal extraction conditions of phenolic compounds were determined as follows: Ultrasonic extraction time 30.61 min, ratio of water to raw material 30.79 mL/g and ethanol concentration 42.2%. Under these conditions, the experimental yield of phenolic compounds was 8.2409 ± 0.0648‰, well matched with the predicted models with the coefficients of determination (R2) of 0.9920, which was agreed closely with the predicted value (8.2963‰).

scholarly journals Box-Behnken Experimental Design for Extraction of Spinosin from Ziziphus mauritiana Lam. Seeds

2019 ◽  
Vol 31 (5) ◽  
pp. 1045-1048
Author(s):  
Quang Thuong Tran ◽  
Loan Thi Thanh Vu ◽  
Tram Huyen Le ◽  
Ly Thi Phuong Giang ◽  
Toyonobu Usuki
Keyword(s):  
Response Surface Methodology ◽  
Experimental Design ◽  
Factorial Design ◽  
Response Surface ◽  
Ethanol Concentration ◽  
Raw Material ◽  
Extraction Time ◽  
Ziziphus Mauritiana ◽  
Solid Ratio ◽  
Extraction Parameters

The objective of this study was to evaluate the effects of extraction parameters (ethanol concentration, extraction ratio of solvent to raw material and extraction time) on the yield of spinosin from the seeds of Ziziphus mauritiana Lam. Box-Behnken factorial design was used in association with response surface methodology. The optimal extraction conditions were an ethanol concentration of 61 %, 40 (v/w) liquid-to-solid ratio, and 2.6 h extraction time with reflux. Spinosin was purified using Diaion HP20SS as an adsorbent. The maximum spinosin yield was 1.18 mg/g raw material. Present findings can be applied to future approaches for maximizing the extraction of spinosin from Z. mauritiana Lam. seeds.

Extraction of Polysaccharide From Zizyphus Lotus Fruits

2012 ◽  
Vol 8 (3) ◽  
Author(s):  
Moncef Chouaibi ◽  
Leila Rezig ◽  
Khaled Ben daoued ◽  
Nesrine Mahfoudhi ◽  
Habib Bouhafa ◽  
...  
Keyword(s):  
Response Surface ◽  
Ethanol Concentration ◽  
Gel Permeation Chromatography ◽  
Processing Parameters ◽  
Physicochemical Analysis ◽  
Raw Material ◽  
Extraction Time ◽  
Extraction Temperature ◽  
Optimal Processing ◽  
Contour Plots

Abstract In this study, response surface methodology (RSM) was used to optimize the extraction conditions of polysaccharides from the pulp of Zizyphus lotus fruit. A central composite rotatable design (CCRD) was used for experimental design and analysis of the results to obtain the optimal processing parameters. Ethanol concentration, extraction temperature, extraction time and water to raw material ratio were found to have a significant effect ( p < 0.05) on the yield of Zizyphus lotus polysaccharide. The 3-D response surface and contour plots, derived from the mathematical model, were applied to determine the optimal conditions. The optimum conditions were as follows: water to raw material ratio 22.04:1, ethanol concentration of 83.30 %, extraction time of 2.65 h, and extraction temperature of 66.31 °C. Under these conditions, the experimental percentage value was 17.35±0.07 %, which is in well close agreement with the value predicted by the model (17.29 %). The results of physicochemical analysis showed that the main sugar composition of Zizyphus lotus polysaccharide, purified by Sephadex G-75 gel permeation chromatography, was glucose followed by arabinose, mannose and rhamnose.

scholarly journals Simultaneous Optimization of Microwave-Assisted Extraction of Phenolic Compounds and Antioxidant Activity of Avocado (Persea americana Mill.) Seeds Using Response Surface Methodology

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Alexander Weremfo ◽  
Felix Adulley ◽  
Martin Adarkwah-Yiadom
Keyword(s):  
Antioxidant Activity ◽  
Response Surface Methodology ◽  
Phenolic Compounds ◽  
Response Surface ◽  
Microwave Power ◽  
Ethanol Concentration ◽  
Extraction Time ◽  
Microwave Assisted Extraction ◽  
Microwave Assisted ◽  
Assisted Extraction

This study was designed to optimize three microwave-assisted extraction (MAE) parameters (ethanol concentration, microwave power, and extraction time) of total phenolics, total flavonoids, and antioxidant activity of avocado seeds using response surface methodology (RSM). The predicted quadratic models were highly significant (p<0.001) for the responses studied. The extraction of total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity was significantly (p<0.05) influenced by both microwave power and extraction time. The optimal conditions for simultaneous extraction of phenolic compounds and antioxidant activity were ethanol concentration of 58.3% (v/v), microwave power of 400 W, and extraction time of 4.8 min. Under these conditions, the experimental results agreed with the predicted values. MAE revealed clear advantages over the conventional solvent extraction (CSE) in terms of high extraction efficiency and antioxidant activity within the shortest extraction time. Furthermore, high-performance liquid chromatography (HPLC) analysis of optimized extract revealed the presence of 10 phenolic compounds, with rutin, catechin, and syringic acid being the dominant compounds. Consequently, this optimized MAE method has demonstrated a potential application for efficient extraction of polyphenolic antioxidants from avocado seeds in the nutraceutical industries.

Response Surface Methodology for Optimization of the Ultrasonic Extraction of Polysaccharides from Melaleuca ahemifolia

2013 ◽  
Vol 655-657 ◽  
pp. 1987-1995
Author(s):  
Yue Xiao ◽  
He Ping Yu ◽  
Li Jing Lin
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Polynomial Equation ◽  
Extraction Yield ◽  
Raw Material ◽  
Extraction Time ◽  
Ultrasonic Power ◽  
Ultrasonic Assisted ◽  
Experimental Yield ◽  
Optimum Extraction

An ultrasonic-assisted procedure for the extraction of polysaccharides from Melaleuca ahemifolia was investigated using response surface methodology (RSM). A Box–Behnken design (BBD) was employed to investigate the effects of extraction time, ratio of water to raw material and ultrasonic power on the extraction yield of polysaccharides.The statistical analysis indicated that three variables and the quadratic terms had significant effects on the yield (p＜0.05). The experimental data obtained were fitted to a second-order polynomial equation using multiple regression analysis and further analyzed by appropriate statistical methods (ANOVA). The optimum extraction conditions were as follows: extraction time of 21 min, ratio of water to raw material of 40, ultrasonic power of 170 W. Under the optimization conditions, the experimental yield of polysaccharides was 6.194%, which was in good agreement with the predicted value (6.288%).

Optimization of Ultrasonic Extraction Process by Response Surface Methodology of Polysaccharides from Tussilago farfara L.

2013 ◽  
Vol 771 ◽  
pp. 41-44
Author(s):  
Peng Zhao ◽  
Xiao Song
Keyword(s):  
Response Surface Methodology ◽  
Extraction Process ◽  
Ultrasonic Extraction ◽  
Raw Material ◽  
Extraction Time ◽  
Ultrasonic Power ◽  
Extraction Temperature ◽  
Tussilago Farfara ◽  
Optimum Extraction ◽  
Extraction Power

Polysaccharides from Tussilago farfara L.(TFPs) was extracted with the assistance of ultrasonic.Box-Behnken design (BBD) was employed to optimize extraction time; extraction temperature;ultrasonic extraction power and ratio of water to raw material to obtain a high TFPs yield.The optimum extraction conditions were as follows: extraction temperature 65.1°C, ultrasonic power 380.5W, extraction time 28.7 min and ratio of water to raw material 23.6ml/g.The yield of polysaccharide was 2.14% based on the above mentioned conditions.

scholarly journals Optimization of Ultrasonic-assisted Extraction of Total Phenolic Compound from Leaves of Chromolaena Odorata L. Using Response Surface Methodology

2021 ◽  
Vol 333 ◽  
pp. 06005
Author(s):  
Guntima Sirijeerachai ◽  
Suphattra Khunasinkun ◽  
Piyapassara Boonleau ◽  
Ratchadaporn Oonsivilai ◽  
Aroonsri Nuchitprasitchai
Keyword(s):  
Response Surface Methodology ◽  
Phenolic Compounds ◽  
Medicinal Plants ◽  
Response Surface ◽  
Aqueous Ethanol ◽  
Ethanol Concentration ◽  
Extraction Time ◽  
Total Phenolic ◽  
Chromolaena Odorata ◽  
Assisted Extraction

Chromolaena odorata L. or C. odorata is a weed that found in tropical continents . Leaves, roots and flowers of C. odorata have been used as medicinal plants for centuries. Preliminary phytochemical screening showed the chemical composition of its extracts having phenolic compounds such as flavonoids, saponins, tannins and steroids. The total phenolic compounds (TPC) in medicinal plants are acknowledged as biochemical activities such as antiinflammatory, antiviral, antimicrobial, antioxidant agents and etc. This work is interested in antioxidant and antimicrobial activity of an ethanolic extract of C. odorata leaves. Though, many solvents can be used to extract TPC from plants. Ethanol with ultrasound assisted extraction was selected. The response surface methodology coupled with the nonlinear solver were used to find the optimal extraction variables. The Central Composite Design (CCD) was employed as the sampling technique. Three variables are the ratio of ethanol to the dried leaves of C. odorata (X1), aqueous ethanol concentration (X2), and the extraction time (X3). The extraction conditions were fixed at 40 kHz and 60 ˚C. The maximum yield of TPC was 111.77 mg GAE/g dry extract at 57 % v/v of aqueous ethanol concentration, 43 mL of solvent/g of dried sample and 35 minutes extraction time.

scholarly journals Homogenate Extraction of Crocins from Saffron Optimized by Response Surface Methodology

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Yingpeng Tong ◽  
Yu Jiang ◽  
Dan Guo ◽  
Yongqiu Yan ◽  
Shiping Jiang ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Ethanol Concentration ◽  
Extraction Yield ◽  
Extraction Time ◽  
Process Conditions ◽  
Extraction Temperature ◽  
Single Factor ◽  
Extraction Voltage ◽  
Homogenate Extraction

Saffron, which has many kinds of biological activities, has been widely used in medicine, cosmetics, food, and other fields of health promotion industries. Crocins are the main component of saffron (Crocus sativus L.). At present, most of the extraction methods for crocins require long time or special instruments to complete the process and some of them are not suitable for industrial production at present. In this article, homogenate extraction technology which is a convenient and efficient method was developed for crocins extraction from saffron. Firstly, the influences of extraction voltage, extraction time, ethanol concentration, and temperature on crocins yield were studied by single factor experiments; and then response surface methodology (RSM) was used to optimize levels of four variables based on the result of single factor experiments. Results showed that the optimum extraction process conditions for crocins were as follows: extraction voltage, 110 V; ethanol concentration, 70%; extraction temperature, 57°C; and extraction time, 40 s. Based on these conditions, the extraction yield of crocins can reach 22.76% which is higher than ultrasonic extraction method. Therefore, homogenate extraction is an effective way to extract crocins from saffron with higher extraction yield and shorter extraction time.

scholarly journals Effects of Ultrasonic-Microwave-Assisted Technology on Hordein Extraction from Barley and Optimization of Process Parameters Using Response Surface Methodology

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Xiao Guan ◽  
Lv Li ◽  
Jing Liu ◽  
Sen Li
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Microwave Power ◽  
Process Intensification ◽  
Extraction Yield ◽  
Extraction Time ◽  
Quadratic Model ◽  
Ultrasonic Power ◽  
Microwave Assisted ◽  
The Difference

We investigated the process intensification of ultrasonic-microwave-assisted technology for hordein extraction from barley. Response surface methodology was utilized to optimize the extraction conditions and to analyze the interaction between four selected variables: temperature, microwave power, ultrasonic power, and extraction time. The validated extraction yield of hordein reached 8.84% at 78°C, microwave power 298 W, and ultrasonic power 690 W after 20 min as optimum conditions. Compared with traditional water-bath extraction (4.7%), the ultrasonic-microwave-assisted technology effectively increased the hordein extraction yield and shortened the extraction time. According to the obtained quadratic model (R2 = 0.9457), ultrasonic power and extraction time were the first two significant factors. However, temperature limited the effects of other factors during extraction. SDS-PAGE and scanning electron microscopy were used to identify the hordein extract and to clarify the difference between the two hordein fractions extracted with new and traditional methods, respectively. Ultrasonic-microwave-assisted technology provided a new way to improve hordein extraction yield from barley and could be a good candidate for industrial application of process intensification.

Optimization of Microwave Extraction Process by Response Surface Methodology of Flavonoids from Tussilago farfara L.

2013 ◽  
Vol 763 ◽  
pp. 246-249
Author(s):  
Xiao Song ◽  
Peng Zhao
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Microwave Power ◽  
Extraction Process ◽  
Raw Material ◽  
Extraction Time ◽  
Microwave Extraction ◽  
Water Solvent ◽  
Tussilago Farfara ◽  
Optimum Extraction

Flavonoids from Tussilago farfara L. was extracted with the assistance of microwave.Box-Behnken design (BBD) was employed to optimize extraction time; microwave power and ratio of water to raw material to obtain a high flavonoids yield.The optimum extraction conditions were as follows: 73.3% ethanol-water solvent, time 16.25 min and ratio of solvent to raw material 36.2ml/g.The yield of flavonoids was 11.37% based on the above mentioned conditions.

Research on Biochemical Materials with Optimization of Microwave Extraction Process by Response Surface Methodology of Flavonoids from Platycarya strobi lacea sieb.et zucc.

2014 ◽  
Vol 1014 ◽  
pp. 61-64
Author(s):  
Xiao Song ◽  
Peng Zhao ◽  
Qing Hua Meng ◽  
Zhi Shu Tang ◽  
Chang Li Wang
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Microwave Power ◽  
Extraction Process ◽  
Raw Material ◽  
Extraction Time ◽  
Microwave Extraction ◽  
Water Solvent ◽  
Optimum Extraction

Flavonoids from Platycarya Strobi lacea Sieb.et Zucc. was extracted with the assistance of microwave.Box-Behnken design (BBD) was employed to optimize extraction time; microwave power and ratio of solvent to raw material to obtain a high flavonoids yield. The optimum extraction conditions were as follows: 65.32% ethanol-water solvent, time 3.96 min and ratio of solvent to raw material 20.8 ml/g.The yield of flavonoids was 3.41% based on the above mentioned conditions.

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