Effects of Addition Amount, Particle Size Distribution and Average Particle Size of NaCl Porogen on the Pore Connectivity of Silk Fibroin (SF) /Hydroxyapatite (HA) Porous Composites
In order to investigate the effects of addition amount, particle size distribution and aver- age particle size of NaCl porogen on the pore connectivity of silk fibroin (SF) / hydroxyapatite (HA) porous composites. In this paper, the SF/HA composites were fabricated by means of isostatic pressing. The pore structure of SF/HA porous composites was observed by Scanning electron microscopy (SEM), and the air permeability was tested by home-made device. Results indicated that the larger addition amount of NaCl particles, the greater scope of NaCl particles size distribution and increased the average particle size of NaCl particles were able to make the pore connectivity of the material improved significantly. The materials with good pore connectivity, which were conducive to the immigration and adhesion of bone repair cells, information transmission and exchange with the outside tissue, and also benefit for bone tissue regeneration.