QSAR Study on Toxic Effects of Reactive Organic Compounds

2013 ◽  
Vol 726-731 ◽  
pp. 175-178
Author(s):  
Zhi Min Cao ◽  
Zhen Zhen Wu ◽  
Zhi Fen Lin
Keyword(s):  
Risk Assessment ◽  
Adverse Effects ◽  
Physicochemical Properties ◽  
Human Health ◽  
Health Effects ◽  
Organic Compounds ◽  
Environmental Fate ◽  
Qsar Modeling ◽  
Qsar Study ◽  
Human Health Effects

There is an essential need to use computation-based quantitative structureactivity relationship (QSAR) modeling for providing information about the physicochemical properties of chemicals and their environmental fate as well as their human health effects. The major aims of this paper is to explore ways to predict and to identify hazardous combinations of chemicals relevant to humans and the environment. So we use QSAR modeling for toxicological predictions determine the potential adverse effects of reactive organic compounds in risk assessment.

Chemical-based risk assessment and in vitro models of human health effects induced by organic pollutants in soils from the Olona valley

2013 ◽  
Vol 463-464 ◽  
pp. 790-801 ◽  
Author(s):  
Diego Baderna ◽  
Andrea Colombo ◽  
Giorgia Amodei ◽  
Stefano Cantù ◽  
Federico Teoldi ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Human Health ◽  
Health Effects ◽  
Organic Pollutants ◽  
In Vitro Models ◽  
Human Health Effects

An Overview of Endocrine Modulators

1998 ◽  
Vol 17 (2) ◽  
pp. 105-110 ◽  
Author(s):  
Daniel M. Byrd ◽  
William H. Benson ◽  
Keith R. Solomon ◽  
John A. Thomas ◽  
William J. Waddell
Keyword(s):  
Adverse Effects ◽  
Human Health ◽  
Health Effects ◽  
Scientific Information ◽  
Endocrine System ◽  
Toxic Effects ◽  
System 2 ◽  
Valley Forge ◽  
Human Health Effects ◽  
Endocrine Modulation

During the American College of Toxicology's Symposium on Endocrine Modulators (Valley Forge, PA, November 1996), the speakers evaluated relevant scientific information and discussed three general ideas, as follows: (1) The available epidem iological data are inconsistent with significant increases in observed human health effects that might relate to the modulation of the endocrine system. (2) Environm ental contarn in ants have produced toxic effects in wildlife at specific locations. In select instances, the adverse effects observed may involve modulation of endocrine pathways. (3) Additional research focused on endocrine modulation is desirable in order to address this issue within a sound, scientificframework.

scholarly journals Risk Assessment of Emitted Particle-bound Polycyclic Aromatic Hydrocarbons from Lignite-biomass Pelletization Burning: Size Distribution and Human Health Effects

2018 ◽  
Vol 16 (10) ◽  
pp. 805-816
Author(s):  
Rithy KAN ◽  
Thaniya KAOSOL ◽  
Perapong TEKASAKUL ◽  
Surajit TEKASAKUL
Keyword(s):  
Risk Assessment ◽  
Polycyclic Aromatic Hydrocarbons ◽  
Human Health ◽  
Size Distribution ◽  
Health Effects ◽  
Aromatic Hydrocarbons ◽  
Ultrafine Particles ◽  
Toxic Substances ◽  
Polycyclic Aromatic ◽  
Human Health Effects

Risk assessment of emitted particle polycyclic aromatic hydrocarbons (PAHs) from lignite-biomass pelletization burning focusing on size distribution and human health effects are investigated. The particles and PAHs are experimented by a tube furnace and high performance liquid chromatography coupled diode array and fluorescence detectors (HPLC-DAD/FLD), respectively. The carcinogenic, mutagenic, and toxic potencies of PAHs are also discussed in relative to the size distribution of emitted particle PAHs. The results indicate that the carcinogenic, mutagenic, and toxic potencies of PAHs are like to accumulate in the ultrafine particles finer than 0.65 µm. The ultrafine particles contribute the largest PAHs existences of carcinogenic, mutagenic and toxic substances; even though they register in the small mass fraction of PAHs.  Moreover, the co-pellets burning can reduce the values of carcinogenic PAHs, carcinogenic equivalency quotients (BaP-TEQ), mutagenic equivalency quotients (BaP-MEQ), and toxic equivalency quotients (TCDD-TEQ) by more than 60%.

Human Health Effects of Microplastics in Drinking Water: A Review

2021 ◽  
pp. 40-43
Author(s):  
PA Ganichev
Keyword(s):  
Drinking Water ◽  
Human Health ◽  
Health Effects ◽  
Citation Index ◽  
Russian Science ◽  
The Past ◽  
Russian Science Citation Index ◽  
Human Health Effects ◽  
Published Research ◽  
Potential Human Health

Introduction: Polymer products have become inexpensive, convenient and widely used in all spheres of everyday life recently. Microplastics are found in seawater, wastewater, fresh water, foodstuffs, and air. Over the past few years, the presence of microplastics in treated tap and bottled water has been reported, raising questions and concerns about their potential human health effects. Objective: To summarize and systematize the results of studying health effects of exposure to microplastics in potable water. Materials and methods: A literature review was done based on ten topical articles and reviews published in 2014–2021 out of 64 sources found in the PubMed and Scopus international databases and the Russian Science Citation Index (RSCI). Results and conclusions: Generalization and systematization of the published research data demonstrated the lack of strong evidence to draw conclusions about human health effects of microplastics. Information on toxicokinetics and toxicodynamics of ingested microplastic particles is absent just like the studies of the most common shapes and sizes of plastic particles and health risks from exposure to such particles in drinking water.

Chromium in the Canadian environment

1995 ◽  
Vol 3 (1) ◽  
pp. 121-144 ◽  
Author(s):  
Jerome O. Nriagu ◽  
Abdul Kabir
Keyword(s):  
Human Health ◽  
Health Effects ◽  
Surface Waters ◽  
Soil Microorganisms ◽  
Local Scale ◽  
Aquatic Biota ◽  
Chromium Toxicity ◽  
Toxicity Threshold ◽  
Environmental Media ◽  
Human Health Effects

The widening use of chromium and its compounds by local industries has led to a growing concern about the effects of chromium contamination on the Canadian environment. This report summarizes the data on Canadian sources and the concentrations of chromium in air, water, sediments, soil, terrestrial wildlife and aquatic biota. It reviews what little is currently known about the cycling of chromium in Canadian ecoystems, and the need for measuring Cr(III) and Cr(VI) rather than total Cr in the environmental media is emphasized. The potential effects of elevated levels of chromium on plants, soil microorganisms, wildlife, and aquatic biota are discussed. The human health effects are not covered. The conclusion is reached that chromium pollution has become a threat to Canadian ecosystems, especially at the local scale where the ambient chromium concentrations in some surface waters, sediments, and soils are now close to or above the toxicity threshold for a number of the more sensistive organisms.Key words: chromium pollution, chromium toxicity, chromium chemistry, chromium emission, bioaccumulation of chromium.

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