Bioactive and Stability of Calcium Phosphate-Polypyrrole Composite Coatings by Electrochemical Deposition

2008 ◽  
Vol 368-372 ◽  
pp. 1198-1200 ◽  
Author(s):  
Mu Qin Li ◽  
Li Jie Qu ◽  
Chen Ma ◽  
Shi Qin Yang
Keyword(s):  
Calcium Phosphate ◽  
Electrochemical Deposition ◽  
Body Fluid ◽  
Composite Coatings ◽  
Therapeutic Agents ◽  
Calcium Phosphate Coating ◽  
Implant Fixation ◽  
The Stability ◽  
Polypyrrole Composite ◽  
Single Coating

This study examined the bioactive and stability of calcium phosphate- polypyrrole(ppy) composite coatings on titanium alloys by electrochemically deposition in simulated body fluid (SBF). Change of coatings mass and SBF pH during coatings soaked in SBF indicated that ppy reduces the decomposition of coatings. The surface morphology of coatings characterized by SEM showed that the stability of composition coating was superior to that of single coating. XRD indicated that ppy induces CO3 2- enter calcium phosphate coating, which showed that the composite coatings possess better bioactive. Thus, this electrochemical deposition provides an effective method of ppy incorporation at physiological temperature, which can offer excellent bioactive and stability of coatings, with a potential for sustained release of therapeutic agents as required for metallic implant fixation.

Corrosion Protection of Nano-biphasic Calcium Phosphate Coating on Titanium Substrate

2020 ◽  
Vol 16 (5) ◽  
pp. 779-792
Author(s):  
Ahlam M. Fathi ◽  
Howida S. Mandour ◽  
Hanaa K. Abd El-Hamid
Keyword(s):  
Calcium Phosphate ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Biphasic Calcium Phosphate ◽  
Titanium Surface ◽  
Electrochemical Impedance ◽  
Calcium Phosphates ◽  
Diffusion Method ◽  
Calcium Phosphate Coating ◽  
Chemical Compositions

Background: Increasing the bioactivity of metallic implants is necessary for biomaterial applications where hydroxyapatite (HA) is used as a surface coating. In industry, HA is currently coated by plasma spraying, but this technique has a high cost and produces coating with short-term stability. Objectives: In the present study, electrophoretic deposition (EPD) was used to deposit nano-biphasic calcium phosphate compound (β-tri-calcium phosphate (β-TCP) /hydroxyapatite (HA)) bio-ceramics on the titanium surface. The microstructural, chemical compositions and bioactivity of the β- TCP/HA coatings were studied in a simulated body fluid solution (SBF). Methods: Scanning electron microscopy (SEM) equipped with energy-dispersive X-ray spectroscopy (EDX) and Fourier transform infrared spectroscopy (FTIR) were used. Additionally, the antibacterial effect was studied by the agar diffusion method. The corrosion behavior of the β-TCP/HA coating on titanium surface (Ti) in the SBF solution at 37oC was investigated by means of electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization tests. Results: The Ti surface modification increased its biocompatibility and corrosion resistance in the simulated body fluid. The antibacterial inhibition activity of the β-TCP/HA bio-ceramic was enhanced by electroless silver deposition. The enhanced properties could be attributed to the use of nano-sized biphasic calcium phosphates in a low-temperature EPD process. Conclusions: The β-TCP/HA and β-TCP/HA/Ag coatings well protect Ti from the corrosion in SBF and endow Ti with biocompatibility. The β-4-TCP/HA/Ag/Ti substrate shows good antibacterial activity.

Growth of Calcium Phosphate Coating on Ti-7.5Mo Alloy after Anodic Oxidation

2013 ◽  
Vol 334-335 ◽  
pp. 297-302 ◽  
Author(s):  
A.L.A. Escada ◽  
João Paulo Barros Machado ◽  
Roberto Zenhei Nakazato ◽  
Ana Paula Rosifini Alves Claro
Keyword(s):  
Calcium Phosphate ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Calcium Phosphates ◽  
Sodium Titanate ◽  
Ammonium Fluoride ◽  
Biological Properties ◽  
Calcium Phosphate Coating ◽  
Phosphate Coating

Titanium and its alloys are widely used as biomaterials due to their mechanical, chemical and biological properties. To enhance the biocompatibility of titanium alloys, various surface treatments have been proposed. In particular, the formation of titanium oxide nanotubes layers has been extensively examined. Among the various materials for implants, calcium phosphates and hydroxyapatite are widely used clinically. In this work, titanium nanotubes were fabricated on the surface of Ti-7.5Mo alloy by anodization. The samples were anodized for 20 V in an electrolyte containing glycerol in combination with ammonium fluoride (NH4F, 0.25%), and the anodization time was 24 h. After being anodized, specimens were heat treated at 450 °C and 600°C for 1 h to crystallize the amorphous TiO2 nanotubes and then treated with NaOH solution to make them bioactive, to induce growth of calcium phosphate in a simulated body fluid. Surface morphology and coating chemistry were obtained respectively using, field-emission scanning electron microscopy (FEG-SEM), AFM and X-ray diffraction (XRD). It was shown that the presence of titanium nanotubes induces the growth of a sodium titanate nanolayer. During the subsequent in-vitro immersion in a simulated body fluid, the sodium titanate nanolayer induced the nucleation and growth of nanodimensioned calcium phosphate. It was possible to observe the formation of TiO2 nanotubes on the surface of Ti-7.5Mo. Calcium phosphate coating was greater in the samples with larger nanotube diameter. These findings represent a simple surface treatment for Ti-7.5Mo alloy that has high potential for biomedical applications.

Thin calcium phosphate coatings on titanium by electrochemical deposition in modified simulated body fluid

2005 ◽  
Vol 76A (2) ◽  
pp. 347-355 ◽  
Author(s):  
Ping Peng ◽  
Sunil Kumar ◽  
Nicolas H. Voelcker ◽  
Endre Szili ◽  
Roger St. C. Smart ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Simulated Body Fluid ◽  
Electrochemical Deposition ◽  
Body Fluid ◽  
Phosphate Coatings ◽  
Calcium Phosphate Coatings

Electrochemical deposition of polyaniline-polypyrrole composite coatings on aluminum

2002 ◽  
Vol 83 (9) ◽  
pp. 1970-1977 ◽  
Author(s):  
Gouri Smitha Akundy ◽  
Ramakrishnan Rajagopalan ◽  
Jude O. Iroh
Keyword(s):  
Electrochemical Deposition ◽  
Composite Coatings ◽  
Polypyrrole Composite

EFFECT OF ALENDRONATE-CONTAINING COATINGS ON OSTEOINTEGRATION INTO POROUS TANTALUM IN A CORTICAL BONE MODEL

Nano LIFE ◽  
2012 ◽  
Vol 02 (01) ◽  
pp. 1250007 ◽  
Author(s):  
KE DUAN ◽  
YOUXIN HU ◽  
KAREN LONG ◽  
ANDREW TOMS ◽  
HELEN M. BURT ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Formation ◽  
Drug Dose ◽  
Calcium Phosphate Coating ◽  
Phosphate Coating ◽  
New Bone Formation ◽  
Implant Fixation ◽  
Porous Tantalum ◽  
High Drug ◽  
Drug Coating

Hip replacement is extensively performed in hips with serious damages. The clinical outcomes of hip implants remain to be improved. Local delivery of bisphosphonates may improve implant fixation by positively affecting local bone modeling. In this study, two alendronate-containing coatings were prepared on porous tantalum by electrolytic deposition. Calcium phosphate coating was deposited and adsorbed with alendronate; the resulting coating had a low drug dose and slow release rate. Solid calcium alendronate coating was also deposited on tantalum; the resulting coating had high drug dose and faster release rate. The effects of the two coatings on new bone formation and implant fixation were studied in the rabbit tibial cortex. Four weeks after implantation, the implants with adsorbed alendronate showed the highest total new bone formation and mechanical fixation, whereas the implants with solid drug coating showed slightly lower fixation and total new bone formation than control bare implants. The improvement by the alendronate-adsorbed calcium phosphate coating provides potentials of enhancing early fixation of porous implants. The solid drug coating warranted further studies to exploit its high drug dose for inhibiting future osteolysis.

Collagen-calcium Phosphate Composite Coatings by Electrolysis-induced Self-assembly and Mineralization

2004 ◽  
Vol 823 ◽  
Author(s):  
Yuwei Fan ◽  
Ke Duan ◽  
Rizhi Wang
Keyword(s):  
Calcium Phosphate ◽  
Composite Coating ◽  
Collagen Fibril ◽  
Bone Growth ◽  
Composite Coatings ◽  
Composite Layer ◽  
Biological Tissues ◽  
Electrolytic Deposition ◽  
Calcium Phosphate Coating ◽  
Deposition Condition

AbstractA bone-like composite coating of collagen protein and calcium phosphate minerals is considered to be bioactive and may enhance bone growth and fixation of metallic orthopedic implants. In this study, we have successfully prepared a uniform collagen fibril/octacalcium phosphate composite coating on silicon substrate by electrolytic deposition. Under a typical deposition condition, a thin (100 nm) layer of calcium phosphate coating would form on the cathode (Si) surface first, which was followed by a thick (∼100 μm) composite coating. The porous composite layer consists of a collagen fibril network on which clusters of octacalium phosphate crystals nucleate and grow. The results not only provide a novel bioactive coating for biomedical implants, but also establish a new experimental protocol for studying biomineralization mechanisms of collagen based biological tissues.

Sign in / Sign up

Export Citation Format

Share Document