Synthesis AgNPs in Starch Solution by Green Method for New Medical Drugs

2020 ◽  
Vol 1002 ◽  
pp. 311-318
Author(s):  
Azhar J. Bohan ◽  
Duha S. Ahmed ◽  
Ghaed K. Salman

Work represents the silver nanoparticles synthesis using green method by adding soluble starch in DMSO solution. The resulting AgNPs-based starch was noted via changing the color from yellow to brownish in aqueous DMSO solution in dark place due to the role of starch in the Ag ions reduction to AgNPs as capping agent in DMSO solvent at temperature 60°C. Then, the AgNPs development was characterized via the (UV-Vis) spectrophotometer. The morphology, structure and polydispersion of AgNPs were determined by using FESEM, XRD and Zeta analyzer, respectively which improved the role of starch in the formation of spherical and flower shapes of AgNPs. Moreover, the antibacterial activity of AgNPs-based starch revealed a strong effect against the positive bacteria than the negative bacteria as compared with the other antibiotic. Besides, these results suggest that the AgNPs prepared by green method can be utilized as efficient antimicrobial agent in the fields of medicine and represented the opportunities for the formation of safe and friendly AgNPs.

2018 ◽  
Vol 46 (sup3) ◽  
pp. S572-S584 ◽  
Author(s):  
Prajita Paul ◽  
SureshK. Verma ◽  
Pritam Kumar Panda ◽  
Sangeeta Jaiswal ◽  
Bikash R. Sahu ◽  
...  

2014 ◽  
Vol 3 (1) ◽  
pp. 52-56
Author(s):  
N Prabhu ◽  
P Revathi ◽  
Jeyaseelan T Senthinath ◽  
Robert Asirvatham Alwin ◽  
Pushpa Innocent D Joseph

2020 ◽  
Vol 6 (4) ◽  
pp. 189-196
Author(s):  
Amy Murphy ◽  
Rosheene Galon ◽  
Amit K. Jaiswal ◽  
Swarna Jaiswal

2020 ◽  
Vol 9 (1) ◽  
pp. 451-461 ◽  
Author(s):  
Abid Hussain ◽  
Ansar Mehmood ◽  
Ghulam Murtaza ◽  
Khawaja Shafique Ahmad ◽  
Aneela Ulfat ◽  
...  

AbstractIn this study, we reported an easy, rapid, cost-effective and environmentally benign method for the fabrication of silver nanoparticles (Ag-NPs) using Olea ferruginea as reducing, capping and stabilizing agent. For this, an aqueous extract of leaf and bark of O. ferruginea was treated with 1 mM AgNO3, which reduces Ag ions to Ag-NPs by establishing reddish brown color. The synthesized Ag-NPs were spherical crystals, with a mean size of 23 and 17 nm for leaf- and bark-mediated Ag-NPs, respectively. Fourier transform infrared spectroscopy affirmed the role of leaf and bark extracts of O. ferruginea as reducing, capping and stabilizing agent. These biosynthesized Ag-NPs showed profound antibacterial activity against Gram-negative (Pseudomonas aeruginosa and Escherichia coli) and Gram-positive (Streptococcus pneumonia and Staphylococcus aureus) bacteria. The highest antibacterial activity was shown by bark Ag-NPs against S. aureus (14.00 mm), while leaf Ag-NPs showed higher activity against S. pneumonia (13.00 mm). Additionally, they produced effective antioxidant activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) as compared to plant extracts and positive control. It was observed that the bark-mediated Ag-NPs had higher percentage (90%) of scavenging potential than the leaf-mediated Ag-NPs (78%). The significance of the current study is the synthesis of eco-friendly, easy and cost-effective Ag-NPs as biomedical products.


2020 ◽  
pp. 5-7
Author(s):  
K. Dinesh Singh

Azadirachta indica is a multipurpose tree with multiple health benefits. Different parts of the plant are shown to exhibit antimicrobial effects against a wide variety of micro organisms. In the present study we investigate the antibacterial activity of Azadirachta indica extract against UTI (urinary tract infection) causing bacteria. Silver nanoparticles could be synthesized using the leaves of Azadirachta indica as reducing agent. The resulting silver nanoparticles were characterized using UV-Vis spectrophotometer, X-ray Diffraction (XRD), Scanning Electron Microscope (SEM), and Fourier Transformations Infra Red (FTIR) spectroscopic analysis. The antibacterial activity was assayed by Agar well diffusion method using 20µl each of sterile Nutrient Agar (NA) (Hi-Media) and Potato-Dextrose Agar (PDA). The resulting silver nanoparticles exhibited best inhibitory activities against Escherichia coli and Proteus mirabilis which are main causing agents for UTI.


2014 ◽  
Vol 2 (4) ◽  
pp. 590-598 ◽  
Author(s):  
Genevieve A. Kahrilas ◽  
Wendy Haggren ◽  
Rebecca L. Read ◽  
Laura M. Wally ◽  
Sarah J. Fredrick ◽  
...  

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