Hydroxyapatite Deposition by Alternate Soaking Technique on Poly (Vinyl Alcohol)-Coated Poly (ε-Caprolactone) (PCL) Substrate

2009 ◽  
Vol 610-613 ◽  
pp. 1137-1142 ◽  
Author(s):  
Ling Li Li ◽  
Guang Li ◽  
Jian Ming Jiang ◽  
Yue Wen Guo
Keyword(s):  
Fourier Transform ◽  
Aqueous Solutions ◽  
Vinyl Alcohol ◽  
Calcium Phosphates ◽  
Fourier Transform Infrared ◽  
Poly Vinyl Alcohol ◽  
X Ray Diffraction ◽  
X Ray ◽  
Deposition Amount ◽  
Surface Modified

Biomineralization on surface-modified poly (ε-caprolactone) (PCL) through an alternate soaking process was investigated. A poly(vinyl alcohol) (PVA)-coating on PCL substrate prepared by repetitive adsorption/ drying in an aqueous PVA solution could accelerate hydroxyapatite (HA) deposition while PVA-PCL soaked in aqueous solutions containing Ca2+ and PO3-4 ions alternately. Fourier transform infrared (FTIR) and X-ray diffraction of the apatite verified the formed hydroxyapatite in these processes exhibited a close resemblance with calcium phosphates (HA, Ca10(PO4)6(OH)2). It was also found that the amount of HA formed increased with both soaking with both soaking cycles and deposition amount of PVA on PCL. This study suggested that simple PVA coating on PCL substrate could serve as a novel way to accelerated HAP formation via alternating soaking.

Preparation and Characterization of Octadecylated Poly(vinyl Alcohol) Polymers

2012 ◽  
Vol 482-484 ◽  
pp. 1921-1924 ◽  
Author(s):  
Li Juan Li ◽  
Hai Feng Shi ◽  
Xing Xiang Zhang
Keyword(s):  
Fourier Transform ◽  
Thermal Properties ◽  
Vinyl Alcohol ◽  
Phase Change Materials ◽  
Solid Phase ◽  
Poly Vinyl Alcohol ◽  
X Ray Diffraction ◽  
X Ray ◽  
Storage Properties

Octadecylated poly (vinyl alcohol) (PVA-C18) comb-like polymer was prepared through the reaction between PVA and 1-bromooctadecane via O-alkylation method. The structure, thermal properties and packing mode of PVA-C18 comb-like polymer were detailed investigated with Fourier transform infrared spectroscopy (FTIR), differential scanning calorimeter (DSC), and X-ray diffraction (XRD). The results show that octadecyl side chains had been successfully grafted onto PVA backbones, and PVA-C18 comb-like polymer exhibit the better thermal storage properties with enthalpy of 29.3kJ/mol , indicated that it is one kind of solid-solid phase change materials.

PENINGKATAN LAJU DISOLUSI ACYCLOVIR DENGAN METODE SISTEM DISPERSI PADAT MENGGUNAKAN POLOXAMER 188

2016 ◽  
Vol 5 (1) ◽  
pp. 6
Author(s):  
Budi Setiawan ◽  
Erizal Zaini ◽  
Salman Umar
Keyword(s):  
Electron Microscopy ◽  
Thermal Analysis ◽  
Scanning Electron Microscopy ◽  
Fourier Transform ◽  
Differential Thermal Analysis ◽  
Fourier Transform Infrared ◽  
X Ray Diffraction ◽  
Poloxamer 188 ◽  
X Ray ◽  
Scanning Electron

Sebuah penelitian tentang sistem dispersi padat dari asiklovir dengan poloxamer 188 telah dilakukan formulasi dengan pencampuran secara fisika dengan rasio 1 : 1, 1 : 3, 1 : 5 dan dispersi padat 1 : 1, 1 : 3, 1 : 5 dan penggilingan 1:1 sebagai pembanding. Dispersi padat dibuat menggunakan metode pencairan (fusi), yang digabung dengan poloxamer 188 pada hotplate kemudian asiklovir dimasukkan ke dalam hasil poloxamer 188 lalu di kocok hingga membentuk masa homogen. Semua formula yang terbentuk termasuk asiklovir poloxamer 188 murni dianalisis karakterisasinya dengan Differential Thermal Analysis (DTA), X-ray Diffraction, Scanning Electron Microscopy (SEM), dan Fourier Transform Infrared (FTIR), kemudian pengambilan dilakukan  (penentuan kadar) mengunakan spektrofotometer UV pada panjang gelombang 257,08 nm dan uji laju disolusi dengan aquadest bebas CO2 menggunakan metode dayung. Hasil pengambilan  (penentuan kadar) menunjukkan bahwa semua formula memenuhi persyaratan farmakope Amerika edisi 30 dan farmakope Indonesia edisi 4 yaitu 95-110%. Sedangkan hasil uji laju disolusi untuk campuran fisik 1: 1, dan dispersi padat 1: 1, dan penggilingan 1: 1 menunjukkan peningkatan yang nyata dibandingkan asiklovir murni. Hal ini juga dapat dilihat dari hasil perhitungan statistik  menggunakan analisis varian satu arah  SPSS 17.

Synthesis, characterization, and their some chemical and biological properties of PVA/PAA/nPS hydrogel nanocomposites: Hydrogel and wound dressing

2020 ◽  
Vol 35 (3) ◽  
pp. 203-215
Author(s):  
Mehmet Emin Diken ◽  
Berna Koçer Kizilduman ◽  
Begümhan Yilmaz Kardaş ◽  
Enes Emre Doğan ◽  
Mehmet Doğan ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Acrylic Acid ◽  
Infrared Spectra ◽  
Vinyl Alcohol ◽  
Fourier Transform Infrared ◽  
Poly Vinyl Alcohol ◽  
Seed Particles ◽  
Fourier Transform Infrared Spectra ◽  
Hydrogel Nanocomposites ◽  
Poly Acrylic Acid

The nanocomposite hydrogels were prepared by dispersing of the nanopomegranate seed particles into poly(vinyl alcohol)/poly(acrylic acid) blend matrix in an aqueous medium by the solvent casting method. These hydrogels were characterized using scanning electron microscopy, Fourier transform infrared spectra, differential scanning calorimetry, and optical contact angle instruments. The nanopomegranate seed, blend, and hydrogel nanocomposites were tested for microbial activity. In addition, cytocompatibilities of these blend and hydrogel nanocomposites/composites were tested on human lymphocyte with in vitro MTS cell viability assays. Fourier transform infrared spectra revealed that esterification reaction took place among functional groups in the structure of poly(vinyl alcohol) and poly(acrylic acid). The hydrophilic properties of all hydrogels decreased with increasing nanopomegranate seed content. The mean diameters of the nanopomegranate seed particles were about 88 nm. Nanopomegranate seed particles demonstrated antibacterial properties against gram-positive bacteria, Staphylococcus aureus, and gram-negative bacteria, Escherichia coli. The lymphocyte viabilities increased after addition of nanopomegranate seeds into the polymer blend. The swelling behavior of blend and hydrogels was dependent on the cross-linking density created by the reaction between poly(vinyl alcohol)/poly(acrylic acid) blend and nanopomegranate seed. Scanning electron microscopy images were highly consistent with Fourier transform infrared spectra, differential scanning calorimetry, and antibacterial activity results.

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