A Novel Electrochemiluminscence Sensor for the Detection of Butyl Hydroxy Anisd and Gallic Acid Based on Graphene Quantum Dots

2019 ◽  
Vol 944 ◽  
pp. 721-728
Author(s):  
Chuan Lai Zang ◽  
Cheng Long Wang ◽  
Tiao Hao He ◽  
Wen Jie Liu ◽  
Kai Jun Cao ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Gallic Acid ◽  
Pharmaceutical Analysis ◽  
Graphene Quantum Dots ◽  
High Sensitivity ◽  
Optimum Conditions ◽  
Real Water Samples ◽  
Sensing Platform ◽  
Sensor Field ◽  
Strong Luminescence

Graphene quantum dots (GQDs), with stable photoluminescence (PL) and electrocatalytic activity, have potential application in sensor field. Herein, a facile novel electrochemiluminescence (ECL) sensor based on GQDs and glassy carbon electrode (GCE) was developed to detect Butyl hydroxy anisd (BHA) and Gallic acid. The optimization of ECL detection conditions were investigated. Hence, the sensor exhibited relatively strong luminescence intensity even without the modification of the GCE, which make this sensor system easy to implement. The developed sensor exhibited a linear response ranging from 5 to 160 μM under the optimum conditions. The method displayed the advantages of high sensitivity, good selectivity, wide linear range, low detection limit and fine reproducibility. Moreover, the practicability of the ECL sensing platform in real water samples had shown the satisfactory results, which holds a great potential in the field of pharmaceutical analysis.

Graphene quantum dots supported by graphene oxide as a sensitive fluorescence nanosensor for cytochrome c detection and intracellular imaging

2017 ◽  
Vol 5 (31) ◽  
pp. 6300-6306 ◽  
Author(s):  
Lin Cao ◽  
Xiangqing Li ◽  
Lixia Qin ◽  
Shi-Zhao Kang ◽  
Guodong Li
Keyword(s):  
Quantum Dots ◽  
Graphene Oxide ◽  
Cytochrome C ◽  
Graphene Quantum Dots ◽  
A549 Cells ◽  
High Sensitivity ◽  
Fluorescence Sensor ◽  
Intracellular Imaging ◽  
New Class ◽  
Sensitivity And Selectivity

A new class of Cyt c detection fluorescence sensor based on graphene quantum dots supported by graphene oxide has been facilely developed. The sensor shows a high sensitivity and selectivity for Cyt c detection, and further exhibits favorable intracellular imaging in A549 cells.

scholarly journals Electrochemical detection of white spot syndrome virus with a silicone rubber disposable electrode composed of graphene quantum dots and gold nanoparticle-embedded polyaniline nanowires

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Kenshin Takemura ◽  
Jun Satoh ◽  
Jirayu Boonyakida ◽  
Sungjo Park ◽  
Ankan Dutta Chowdhury ◽  
...  
Keyword(s):  
Quantum Dots ◽  
White Spot Syndrome Virus ◽  
Graphene Quantum Dots ◽  
High Sensitivity ◽  
White Spot ◽  
Sensing Matrix ◽  
Disposable Electrode ◽  
Sensing Applications ◽  
Doped Graphene ◽  
White Spot Syndrome

Abstract Background With the enormous increment of globalization and global warming, it is expected that the number of newly evolved infectious diseases will continue to increase. To prevent damage due to these infections, the development of a diagnostic method for detecting a virus with high sensitivity in a short time is highly desired. In this study, we have developed a disposable electrode with high-sensitivity and accuracy to evaluate its performances for several target viruses. Results Conductive silicon rubber (CSR) was used to fabricate a disposable sensing matrix composed of nitrogen and sulfur-co-doped graphene quantum dots (N,S-GQDs) and a gold-polyaniline nanocomposite (AuNP-PAni). A specific anti-white spot syndrome virus (WSSV) antibody was conjugated to the surface of this nanocomposite, which was successfully applied for the detection of WSSV over a wide linear range of concentration from 1.45 × 102 to 1.45 × 105 DNA copies/ml, with a detection limit as low as 48.4 DNA copies/ml. Conclusion The engineered sensor electrode can retain the detection activity up to 5 weeks, to confirm its long-term stability, required for disposable sensing applications. This is the first demonstration of the detection of WSSV by a nanofabricated sensing electrode with high sensitivity, selectivity, and stability, providing as a potential diagnostic tool to monitor WSSV in the aquaculture industry.

Graphene Quantum Dots Modified Screen‐printed Electrodes as Electroanalytical Sensing Platform for Diethylstilbestrol

2019 ◽  
Vol 31 (5) ◽  
pp. 838-843 ◽  
Author(s):  
Ava Gevaerd ◽  
Craig E. Banks ◽  
Márcio F. Bergamini ◽  
Luiz Humberto Marcolino‐Junior
Keyword(s):  
Quantum Dots ◽  
Graphene Quantum Dots ◽  
Screen Printed Electrodes ◽  
Sensing Platform ◽  
Screen Printed

A fluorometric assay for tyrosinase activity and its inhibitor screening based on graphene quantum dots

RSC Advances ◽  
2016 ◽  
Vol 6 (76) ◽  
pp. 72670-72675 ◽  
Author(s):  
X. E. Zhao ◽  
C. H. Lei ◽  
Y. H. Wang ◽  
F. Qu ◽  
S. Y. Zhu ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Graphene Quantum Dots ◽  
Tyrosinase Activity ◽  
Fluorometric Assay ◽  
Pristine Graphene ◽  
Fluorescence Sensing ◽  
Inhibitor Screening ◽  
Sensing Platform ◽  
First Time

Pristine graphene quantum dots (GQDs) without any functionalization were used as probes to develop a sensitive and selective fluorescence sensing platform for the detection of tyrosinase (TYR) activity and its inhibitor screening for the first time.

Highly Fluorescent N-Doped Carbon Quantum Dots Derived from Bamboo Stems for Selective Detection of Fe3+ Ions in Biological Systems

2021 ◽  
Vol 17 (2) ◽  
pp. 312-321
Author(s):  
Jiamin Yan ◽  
Yuneng Lu ◽  
Shaowen Xie ◽  
Haihu Tan ◽  
Weilan Tan ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Biological Systems ◽  
High Sensitivity ◽  
Carbon Quantum Dots ◽  
Clinical Diagnostics ◽  
Quenching Effect ◽  
Biologically Relevant ◽  
Sensing Platform ◽  
Wide Ph Range ◽  
High Fluorescence

The establishment of sensing platform for trace analysis of Fe3+ in biological systems is meaningful for health monitoring. Herein, a Fe3+ sensitive fluorescent nanoprobe was constructed based on highly fluorescent N-doped carbon quantum dots (NCQDs) derived from bamboo stems through a hydrothermal method employing ethylenediamine as the nitrogen dopant. The prepared NCQDs had a uniformly distributed size and their mean size was around 2.43 nm. Abundant functional groups (C=N, N-H, C=O, and carboxyl) anchored on NCQDs demonstrated successful doping of N in CQDs. The obtained NCQDs possessed a high fluorescence quantum yield of 20.02% and outstanding fluorescence stability over a wide pH range and at high ionic strengths. Moreover, Fe3+ ions presented a specific fluorescent quenching effect to the as-prepared NCQDs. The calibration curve for fluorescence quenching degree corresponding to Fe3+ concentration showed a linear response in a range of 0.01–10 µM, and detection limit was 0.486 µM, which indicated that the NCQDs had high sensitivity to Fe3+ ions. Ascribed to these unique properties, the NCQDs were selected as luminescent probes for trace amount of Fe3+ ions in human serum. These results demonstrated their promising use in clinical diagnostics and other biologically relevant studies.

Sign in / Sign up

Export Citation Format

Share Document