Potential Determinant Factors of Insufficient Milk Supply Syndrome

1994 ◽  
Vol 24 (1) ◽  
pp. 33 ◽  
Author(s):  
Hea Sook Kim
Nutrients ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 974 ◽  
Author(s):  
Luke E. Grzeskowiak ◽  
Mary E. Wlodek ◽  
Donna T. Geddes

Inadequate breast milk supply is a frequently reported reason for early discontinuation of breastfeeding and represents a critical opportunity for intervening to improve breastfeeding outcomes. For women who continue to experience insufficient milk supply despite the utilisation of non-pharmacological lactation support strategies, pharmacological intervention with medications used to augment lactation, commonly referred to as galactagogues, is common. Galactagogues exert their pharmacological effects through altering the complex hormonal milieu regulating lactation, particularly prolactin and oxytocin. This narrative review provides an appraisal of the existing evidence regarding the efficacy and safety of pharmaceutical treatments for lactation insufficiency to guide their use in clinical practice. The greatest body of evidence surrounds the use of domperidone, with studies demonstrating moderate short-term improvements in breast milk supply. Evidence regarding the efficacy and safety of metoclopramide is less robust, but given that it shares the same mechanism of action as domperidone it may represent a potential treatment alternative where domperidone is unsuitable. Data on remaining interventions such as oxytocin, prolactin and metformin is too limited to support their use in clinical practice. The review provides an overview of key evidence gaps and areas of future research, including the impacts of pharmaceutical galactagogues on breast milk composition and understanding factors contributing to individual treatment response to pharmaceutical galactagogues.


2020 ◽  
pp. 1-7
Author(s):  
Mackenzie DM Whipps ◽  
Jill R Demirci

Abstract Objective: To test whether perception of insufficient milk (PIM) supply in the breast-feeding relationship of one child predicts how long mothers breast-feed subsequent children, and whether this association differs for first-time mothers v. mothers with previous children. Design: Secondary analysis of Infant Feeding Practices Study II (ordinary least squares regression) and Year 6 follow-up. Setting: Mailed, self-report survey of US mother–infant dyads, 2005–2012. Participants: Women pregnant with a singleton were recruited from a consumer opinion panel. Exclusion criteria included: mother age <18; infant born <5 lbs, born before 35 weeks or with extended NICU stay, and mother or infant diagnosed with condition that impacts feeding. A subsample with PIM data (n 1460) was analysed. Results: We found that women who weaned because of PIM with the index child stopped breast-feeding 5·7 weeks earlier than those who weaned due to other reasons (4·9 weeks earlier for multiparas, P < 0·001; 7·1 weeks earlier for primiparas, P < 0·001). Using Year 6 follow-up data (n 350), we found subsequent child 1 weaned 9·2 weeks earlier if the mother experiences PIM as a multipara (P = 0·020) and 10·6 weeks earlier if the mother experiences PIM as a primipara (P = 0·019). For subsequent child 2 (n 78), the magnitude of association was even larger, although insignificant due to low power. Conclusions: These findings indicate that PIM may carry forward in the reproductive life course, especially for first-time mothers. Perceptions of breast milk insufficiency and contributors to actual inadequate milk supply with the first child should be targeted, rather than intervening later in the reproductive life course.


Author(s):  
Janet Medforth ◽  
Linda Ball ◽  
Angela Walker ◽  
Sue Battersby ◽  
Sarah Stables

This chapter considers all aspects of breastfeeding. The latest Baby Friendly Initiative standards are detailed, along with the advantages of, and contraindications to, breastfeeding. The constituents of breast milk and their role in infant nutrition are identified. Recently recognized changes in the structure of the lactating breasts are presented. There are detailed sections on the management and support of breastfeeding. Practices shown to be detrimental to successful breastfeeding are highlighted. Expression of breast milk and breastfeeding and returning to work are fully explained, as well as discontinuation of breastfeeding. Common problems encountered whilst breastfeeding are considered, including sore/cracked nipples, engorgement, blocked ducts, mastitis, breast refusal, insufficient milk supply, and Candida infection (thrush). Breastfeeding in special situations is also explored. The importance of correct nutrition and breastfeeding is reviewed.


PLoS ONE ◽  
2009 ◽  
Vol 4 (12) ◽  
pp. e8237 ◽  
Author(s):  
Jacqueline M. Cohen ◽  
Jennifer A. Hutcheon ◽  
Sofi G. Julien ◽  
Michel L. Tremblay ◽  
Rebecca Fuhrer

2016 ◽  
Vol 20 (8) ◽  
pp. 1713-1719 ◽  
Author(s):  
Nicole Kasper ◽  
Karen E. Peterson ◽  
Zhenzhen Zhang ◽  
Kelly K. Ferguson ◽  
Brisa N. Sánchez ◽  
...  

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