scholarly journals The Causes of Acute Fever Requiring Hospitalization in Geriatric Patients: Comparison of Infectious and NoninfectiousEtiology

2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
A. Atahan Cagatay ◽  
Fatih Tufan ◽  
Fehmi Hindilerden ◽  
Sibel Aydin ◽  
Omer Celal Elcioglu ◽  
...  

Introduction. Infectious diseases may present with atypical presentations in the geriatric patients. While fever is an important finding of infections, it may also be a sign of noninfectious etiology.Methods. Geriatric patients who were hospitalized for acute fever in our infectious diseases unit were included. Acute fever was defined as presentation within the first week of fever above .Results. 185 patients were included (82 males and 103 females). Mean age was years. The cause of fever was an infectious disease in 135 and noninfectious disease in 32 and unknown in 18 of the patients. The most common infectious etiologies were respiratory tract infections (), urinary tract infections (), and skin and soft tissue infections (). Noninfectious causes of fever were rheumatic diseases (), solid tumors (), hematological diseases (), and vasculitis (). A noninfectious cause of fever was present in one patient with no underlying diseases and in 31 of 130 patients with underlying diseases.Conclusion. Geriatric patients with no underlying diseases generally had infectious causes of fever while noninfectious causes were responsible from fever in an important proportion of patients with underlying diseases.

Author(s):  
Robert Orenstein

This chapter approaches the field of infectious diseases from 3 perspectives. This second part covers clinical syndromes associated with various infections, such as infective endocarditis, meningitis, sexually transmitted infections, urinary tract infections, gastrointestinal infections, and soft-tissue infections. Symptoms, diagnosis, and treatment of these conditions are reviewed.


Author(s):  
Robert D. Ficalora

Chapter 5 presents multiple-choice, board review questions on infectious diseases including travel medicine, zoonoses, bioterrorism, pneumonia, mycobacterial infections, skin and soft tissue infections, bone and joint infections, urinary tract infections, sexually transmitted infections, gastrointestinal tract infections, and HIV infection. Full explanations are provided with the correct answers.


2019 ◽  
Author(s):  
Luis Felipe Hguita-Gutiérrez ◽  
Valentina Molina ◽  
Jenifer María Acevedo ◽  
Liceth Gómez ◽  
Gustavo Eduardo Roncancio Villamil ◽  
...  

Abstract Background The objective of this study was to describe the knowledge regarding antibiotic therapy of students of three medical schools of Medellín, Colombia. Methods The study population was made up of medical students enrolled in three universities. The instrument contained questions about their current academic term, the university the perceived quality of the education received on antibiotic therapy and bacterial resistance and specific questions on upper respiratory tract infections, pneumonia, urinary tract infections and skin and soft tissue infections. The information was analysed by calculating frequencies and measures of dispersion and central tendency. Knowledge about the treatment of each type of infection was compared with the Mann–Whitney U test and the Kruskal–Wallis H test. Results We included 536 medical students, 43.5% consider that the university did not train them enough to interpret antibiograms, 29.6% consider that the quality of information received on the subject at their university ranges from regular to poor. The mean score for knowledge regarding antibiotic therapy for upper respiratory tract infections was 44.2 ± 9.9 on a scale from 0 to 100. In the treatment of pneumonias, the median score was 52.9 ± 14.7, in urinary tract infection was 58.7 ± 14.8 and skin and soft tissue infections was 63.1 ± 19.4. The knowledge regarding antibiotic therapy for upper respiratory tract infections, pneumonias and urinary tract infection does not improve with academic term, the university, or perception of the education received Conclusion A large proportion of medical students perceive that the training received from the university is deficient regarding antibiotics and bacterial resistance, which coincides with the limited knowledge reflected in the selection of antibiotic treatment for respiratory, urinary tract, skin and soft tissue infections. Overall, the situation is the same among all universities and it does not significantly increase with academic term.


2019 ◽  
Author(s):  
Luis Felipe Hguita-Gutiérrez ◽  
Valentina Molina ◽  
Jenifer María Acevedo ◽  
Liceth Gómez ◽  
Gustavo Eduardo Roncancio Villamil ◽  
...  

Abstract Background The objective of the present study was to describe the knowledge regarding the antibiotic therapy of students of three medical schools in Medellín, Colombia. Methods The study population comprised medical students who were enrolled in three universities. The instrument contained questions regarding their current academic term, the university, the perceived quality of the education received on antibiotic therapy and bacterial resistance, and specific questions on upper respiratory tract infections, pneumonia, urinary tract infections, and skin and soft tissue infections. The information was analyzed by calculating frequencies and measures of dispersion and central tendency. Knowledge regarding the treatment for each type of infection was compared using the Mann–Whitney U test and the Kruskal–Wallis H test. Results We included 536 medical students, of which 43.5% students consider that the university has not sufficiently trained them to interpret antibiograms and 29.6% students consider that the quality of information received on the subject at their university ranges from regular to poor. The mean score for knowledge regarding antibiotic therapy for upper respiratory tract infections was 44.2 (9.9) on a scale from 0 to 100. The median score with regard to the treatment of pneumonia was 52.9 (14.7), that of urinary tract infection was 58.7 (14.8), and that of skin and soft tissue infections was 63.1 (19.4). The knowledge regarding antibiotic therapy for upper respiratory tract infections, pneumonia, and urinary tract infection does not improve with the academic term, the university, or perceived quality of the education received. Conclusion A large proportion of medical students perceive that the training received from the university is insufficient with regard to antibiotic use and bacterial resistance, which is consistent with the limited knowledge reflected in the selection of antibiotic treatment for respiratory, urinary tract, and skin and soft tissue infections. Overall, the situation was identical among all universities, and it did not significantly increase with the completion of an academic term.


2020 ◽  
Author(s):  
Luis Felipe Hguita-Gutiérrez ◽  
Valentina Molina ◽  
Jenifer María Acevedo ◽  
Liceth Gómez ◽  
Gustavo Eduardo Roncancio Villamil ◽  
...  

Abstract Background The objective of the present study was to describe the knowledge regarding the antibiotic therapy of students of three medical schools in Medellín, Colombia. Methods The study population comprised medical students who were enrolled in three universities. The instrument contained questions regarding their current academic term, the university, the perceived quality of the education received on antibiotic therapy and bacterial resistance, and specific questions on upper respiratory tract infections, pneumonia, urinary tract infections, and skin and soft tissue infections. The information was analyzed by calculating frequencies and measures of dispersion and central tendency. Knowledge regarding the treatment for each type of infection was compared using the Mann–Whitney U test and the Kruskal–Wallis H test. Results We included 536 medical students, of which 43.5% students consider that the university has not sufficiently trained them to interpret antibiograms and 29.6% students consider that the quality of information received on the subject at their university ranges from regular to poor. The mean score for knowledge regarding antibiotic therapy for upper respiratory tract infections was 44.2 (9.9) on a scale from 0 to 100. The median score with regard to the treatment of pneumonia was 52.9 (14.7), that of urinary tract infection was 58.7 (14.8), and that of skin and soft tissue infections was 63.1 (19.4). The knowledge regarding antibiotic therapy for upper respiratory tract infections, pneumonia, and urinary tract infection does not improve with the academic term, the university, or perceived quality of the education received. Conclusion A large proportion of medical students perceive that the training received from the university is insufficient with regard to antibiotic use and bacterial resistance, which is consistent with the limited knowledge reflected in the selection of antibiotic treatment for respiratory, urinary tract, and skin and soft tissue infections. Overall, the situation was identical among all universities, and it did not significantly increase with the completion of an academic term.


1997 ◽  
Vol 8 (1) ◽  
pp. 19-27 ◽  
Author(s):  
Michael T Halpern ◽  
Ruth E Brown ◽  
Martine Drolet ◽  
Sonja V Sorensen ◽  
Lionel A Mandell

OBJECTIVE: To evaluate the comparative cost of treatment and intermediate outcomes (percentage resistant organisms, days in hospital, etc) among cefepime and alternative parenteral antibiotics used for empiric monotherapy.DESIGN: Decision analysis model, based on published literature, clinical trial results and information from infectious disease clinicians.SETTING: A Canadian tertiary care hospital.INTERVENTION: Comparison of cefepime, ceftazidime, ceftriaxone, cefotaxime and ciprofloxacin in the treatment of lower respiratory tract infections, urinary tract infections, skin/soft tissue infections, septicemia and febrile neutropenia.MAIN RESULTS: Cefepime treatment results in the lowest average cost per patient when used as initial empiric therapy for lower respiratory tract infections and for skin/soft tissue infections. Cefepime therapy is among the lowest cost treatments for the other infectious disease conditions and has the lowest cost for a weighted ‘average’ condition. Sensitivity analysis indicates that model results are most sensitive to duration of hospitalization.CONCLUSIONS: Initial empiric monotherapy with cefepime for serious infectious disease conditions may result in cost savings compared with alternative parenteral agents.


2021 ◽  
Vol 1 (S1) ◽  
pp. s31-s32
Author(s):  
Amanda Gusovsky ◽  
David Burgess ◽  
Donna Burgess ◽  
Emily Slade ◽  
Chris Delcher ◽  
...  

Background: A team of infectious diseases physicians, infectious diseases pharmacists, clinical laboratorians, and researchers collaborated to assess the management of lower respiratory tract infections (LRTIs). In 1 sample from our institution, 96.1% of pneumonia cases were prescribed antibiotics, compared to 85.0% in a comparison group. A collaborative effort led to the development of a protocol for procalcitonin (PCT)-guided antibiotic prescribing that was approved by several hospital committees, including the Antimicrobial Stewardship Committee and the Healthcare Pharmacy & Therapeutics Committee in December 2020. The aim of this analysis was to develop baseline information on PCT ordering and antibiotic prescribing patterns in LRTIs. Methods: We evaluated all adult inpatients (March–September 2019 and 2020) with a primary diagnosis of LRTI who received at least 1 antibiotic. Two cohorts were established to observe any potential differences in the 2 most recent years prior to adoption of the PCT protocol. Data (eg, demographics, specific diagnosis, length of stay, antimicrobial therapy and duration, PCT labs, etc) were obtained from the UK Center for Clinical and Translational Science, and the study was approved by the local IRB. The primary outcome of interest was antibiotic duration; secondary outcomes of interest were PCT orders, discharge antibiotic prescription, and inpatient length of stay. Results: In total, 432 patients (277 in 2019 and 155 in 2020) were included in this analysis. The average patient age was 61.2 years (SD, ±13.7); 47.7% were female; and 86.1% were white. Most patients were primarily diagnosed with pneumonia (58.8%), followed by COPD with complication (40.5%). In-hospital mortality was 3.5%. The minority of patients had any orders for PCT (29.2%); among them, most had only 1 PCT level measured (84.1%). The median length of hospital stay was 4 days (IQR, 2–6), and the median duration of antibiotic therapy was 4 days (IQR, 3–6). Conclusions: The utilization of PCT in LRTIs occurs in the minority of patient cases at our institution and mostly as a single measurement. The development and implementation of a PCT-guided therapy could help optimize antibiotic usage in patients with LRTIs.Funding: NoDisclosures: None


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