scholarly journals Benefits of Exercise in Rheumatoid Arthritis

2011 ◽  
Vol 2011 ◽  
pp. 1-14 ◽  
Author(s):  
Jennifer K. Cooney ◽  
Rebecca-Jane Law ◽  
Verena Matschke ◽  
Andrew B. Lemmey ◽  
Jonathan P. Moore ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Exercise Training ◽  
Functional Limitation ◽  
Routine Care ◽  
Systemic Autoimmune Disease ◽  
Resistance Exercise Training ◽  
Beneficial Effects ◽  
Rheumatoid Cachexia ◽  
Joint Health

This paper aims to highlight the importance of exercise in patients with rheumatoid arthritis (RA) and to demonstrate the multitude of beneficial effects that properly designed exercise training has in this population. RA is a chronic, systemic, autoimmune disease characterised by decrements to joint health including joint pain and inflammation, fatigue, increased incidence and progression of cardiovascular disease, and accelerated loss of muscle mass, that is, “rheumatoid cachexia”. These factors contribute to functional limitation, disability, comorbidities, and reduced quality of life. Exercise training for RA patients has been shown to be efficacious in reversing cachexia and substantially improving function without exacerbating disease activity and is likely to reduce cardiovascular risk. Thus, all RA patients should be encouraged to include aerobic and resistance exercise training as part of routine care. Understanding the perceptions of RA patients and health professionals to exercise is key to patients initiating and adhering to effective exercise training.

Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis

2012 ◽  
Vol 72 (11) ◽  
pp. 1819-1825 ◽  
Author(s):  
Antonios Stavropoulos-Kalinoglou ◽  
Giorgos S Metsios ◽  
Jet JJCS Veldhuijzen van Zanten ◽  
Peter Nightingale ◽  
George D Kitas ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Cardiovascular Risk ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Cardiorespiratory Fitness ◽  
Resistance Exercise Training

scholarly journals Clinimetric criteria of rheumatoid arthritis

2012 ◽  
Author(s):  
Domenico Galasso ◽  
Massimo L’Andolina ◽  
Norma M. Marigliano ◽  
Salvatore Galasso ◽  
Giovanni Forte
Keyword(s):  
Rheumatoid Arthritis ◽  
Inflammatory Diseases ◽  
Activity Index ◽  
Functional Limitation ◽  
Measurement Scale ◽  
Systemic Autoimmune Disease ◽  
Impact Measurement ◽  
Related Quality ◽  
Health Related ◽  
Active Inflammation

Rheumatoid arthritis is a systemic autoimmune disease, mainly poli-artycular, among wide-spread chronic inflammatory diseases, that cause pain, functional limitation, damage and joints deformations, and disability. It is characterized by turns of active inflammation and remission phases. Inflammation degree and persistence are associated to a bad functional prognosis and progressive joint disability. These patients management require a continuous valuation of inflammatory activity index of disease both therapeutic management and to prevent disablement process. We focus on many valuation index of joint disability and functional damage. Very important are both the scales of auto-values concerning the pain and the joint swelling and clinical data get by physician to valuate activity index of disease as defined by DAS28. Significant data come by health-related quality of life, disability and by AIMS2 (Arthritis Impact Measurement Scale).

scholarly journals Effects of Resistance Exercise on Symptoms, Physical Function, and Quality of Life in Gastrointestinal Cancer Patients Undergoing Chemotherapy

2020 ◽  
Vol 19 ◽  
pp. 153473542095491
Author(s):  
Yijin Hong ◽  
Chunmei Wu ◽  
Biyu Wu
Keyword(s):  
Exercise Training ◽  
Resistance Exercise ◽  
Physical Function ◽  
Cancer Patients ◽  
Gastrointestinal Cancer ◽  
Acid Reflux ◽  
Exercise Group ◽  
Control Group ◽  
Resistance Exercise Training

This research aimed to investigate the effects of resistance exercise on symptoms, physical function, and quality of life (QoL) in gastrointestinal cancer patients undergoing chemotherapy. Patients were quasi-randomly divided into the resistance exercise group and the relaxation control group, and machine-based resistance exercise was performed twice a week for 12 weeks under the guidance of experienced therapists. The QoL of patients was analyzed by EORTC-QLQ-C30. Resistance exercise training significantly reduced the incidences of lack of energy (inter-group P = .011), nausea (inter-group P = .007), acid reflux (inter-group P = .042), and back pain (inter-group P = .0009). Twelve weeks of resistance exercise training significantly elevated the muscular strength of leg press (inter-group P = .021) and leg extension (inter-group P = .041), and the muscular endurance of leg press (inter-group P = .005). The participants’ performance in 6-m fast walk (inter-group P = .008), 6-m backwards walk (inter-group P = .016), and chair rise (inter-group P = .031) were dramatically improved. Fatigue (inter-group P = .024) and appetite loss (inter-group P = .012) in the resistance exercise group were significantly lower than the relaxation control group. In conclusion, the beneficial effects of resistance exercise on symptoms, physical function and QoL in gastrointestinal cancer patients undergoing chemotherapy were demonstrated. Resistance exercise training reduced the incidences of nausea and acid reflux, improved physical function, and alleviated fatigue and appetite loss in gastrointestinal cancer patients undergoing chemotherapy.

scholarly journals Removable prostheses improve OHRQL and satisfaction of elderly people with rheumatoid arthritis

2020 ◽  
Vol 19 ◽  
pp. e206652 ◽  
Author(s):  
Bruna Fernandes Moreira Alfenas ◽  
Kelly Machado de Andrade ◽  
Talita Malini Carletti ◽  
Renata Cunha Matheus Rodrigues Garcia
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Elderly People ◽  
Temporomandibular Disorder ◽  
Functional Limitation ◽  
Mouth Opening ◽  
Functional Impairments ◽  
Oral Rehabilitation ◽  
The Impact

Rheumatoid arthritis (RA) is an autoimmune disease that affects joint tissues and causes severe physical and functional impairments on quality of life due to muscular and articular pain. The involvement of temporomandibular joint in RA interferes with mouth opening and masticatory process. However, no studies addressed the impact of RA on oral health-related quality of life (OHRQoL) and satisfaction with prostheses use in elderly people. Aim: This study assessed the impact of oral rehabilitation with conventional dentures on the OHRQoL and prostheses satisfaction in elderly patients with RA, associated or not with temporomandibular disorder (TMD). Methods: Forty-five elderly were enrolled and divided into three groups: (1) RA and TMD (n=15, experimental), (2) RA without TMD (n=15, experimental), and (3) without RA and without TMD (n=15, control). The OHRQoL and the prostheses satisfaction were evaluated before and after new oral rehabilitation with partial and/or complete dentures. The OHRQoL and prosthesis satisfaction were assessed and verified through OHIP-14 questionnaire and visual analogue scale, respectively. Results: TMD group exhibited the worst mean values (P<0.05) for all OHIP-14 domains before insertion of new dentures. Group 2 showed worst means (P<0.05) compared to controls for functional limitation and physical pain domains of the OHIP-14, but not in the general score. Patients showed better outcomes of satisfaction with prostheses use only after the new rehabilitation. Conclusion: The use of new and well-fitted dentures improves all domains of OHRQoL in patients with RA and TMD and all groups were satisfied with prostheses use after the new rehabilitation with conventional dentures.

Beneficial effects of habitual resistance exercise training on coagulation and fibrinolytic responses

2013 ◽  
Vol 131 (6) ◽  
pp. e227-e234 ◽  
Author(s):  
Brian R. Kupchak ◽  
Brent C. Creighton ◽  
Juan C. Aristizabal ◽  
Courtenay Dunn-Lewis ◽  
Brittanie M. Volk ◽  
...  
Keyword(s):  
Exercise Training ◽  
Resistance Exercise ◽  
Resistance Exercise Training ◽  
Beneficial Effects

Resistance Exercise Training and Quality of Life in Women with Multiple Sclerosis

2006 ◽  
Vol 38 (Supplement) ◽  
pp. S421
Author(s):  
Lesley J. White ◽  
Vanessa Castellano ◽  
Sean C. McCoy ◽  
Darpan I. Patel ◽  
Peter Giacobbi
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Resistance Exercise Training

scholarly journals Regulation of Skeletal Muscle Glucose Transport and Glucose Metabolism by Exercise Training

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2432 ◽  
Author(s):  
Parker L. Evans ◽  
Shawna L. McMillin ◽  
Luke A. Weyrauch ◽  
Carol A. Witczak
Keyword(s):  
Skeletal Muscle ◽  
Glucose Metabolism ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Glucose Transport ◽  
The Body ◽  
Aerobic Exercise Training ◽  
Resistance Exercise Training ◽  
Beneficial Effects ◽  
Muscle Glucose Transport

Aerobic exercise training and resistance exercise training are both well-known for their ability to improve human health; especially in individuals with type 2 diabetes. However, there are critical differences between these two main forms of exercise training and the adaptations that they induce in the body that may account for their beneficial effects. This article reviews the literature and highlights key gaps in our current understanding of the effects of aerobic and resistance exercise training on the regulation of systemic glucose homeostasis, skeletal muscle glucose transport and skeletal muscle glucose metabolism.

scholarly journals Clinical and Laboratory Associations with Methotrexate Metabolism Gene Polymorphisms in Rheumatoid Arthritis

2020 ◽  
Author(s):  
Leon D'Cruz ◽  
Kevin McEleney ◽  
Kyle Tan ◽  
Priyank Shukla ◽  
Philip Gardiner ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Plasma Concentrations ◽  
Systemic Autoimmune Disease ◽  
Single Nucleotide ◽  
Pain Scores ◽  
Metabolite Concentrations ◽  
Lower Pain ◽  
Plasma Metabolite ◽  
The Relationship

Rheumatoid arthritis (RA); is a chronic systemic autoimmune disease which causes loss of joint function and significantly reduces quality of life. Plasma metabolite concentrations of disease-modifying anti-rheumatic drugs (DMARDs) can influence treatment efficacy and toxicity. This study explored the relationship between DMARD metabolising gene variants and plasma metabolite levels in RA patients. DMARD metabolite concentrations were determined by tandem mass-spectrometry in plasma samples from 100 RA patients with actively flaring disease, collected at two intervals. Taqman-probes were used to discriminate single nucleotide polymorphism (SNP) genotypes in cohort genomic DNA: rs246240 (ABCC1), rs1476413 (MTHFR), rs2231142 (ABCG2), rs3740065 (ABCC2), rs4149081 (SLCO1B1), rs4846051 (MTHFR), rs10280623 (ABCB1), rs16853826 (ATIC), rs17421511 (MTHFR) and rs717620 (ABCC2). Mean plasma concentrations of methotrexate (MTX) and MTX-7-OH metabolites were higher (p&lt;0.05, C.I. 95%) at baseline in rs4149081 GA genotype patients. Patients with rs1476413 SNP TT or CT alleles in the have significantly higher (p&lt;0.001, 95% C.I) plasma poly-glutamate metabolites at both study time points and correspondingly elevated disease activity scores. Patients with the rs17421511 SNP AA allele reported significantly lower pain scores (p&lt;0.05, 95% C.I.) at both study intervals. Genotyping strategies could help prioritise treatments to RA patients most likely to gain clinical benefit, whilst minimizing toxicity.

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