scholarly journals Sero-prevalence of human immunodeficiency virus infection among patients with newly diagnosed pulmonary tuberculosis in a teaching hospital in Bauchi, North-Eastern Nigeria

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Sabiu Abdu Gwalabe ◽  
Jacob Dunga ◽  
Yusuf Jibrin Bara ◽  
Alkali Muhammad ◽  
Mustapha Sabo Umar ◽  
...  

About a third of the human immunodeficiency virus (HIV) positive population worldwide is co-infected with Mycobacterium tuberculosis. However, data are lacking about the prevalence of HIV among patients with pulmonary tuberculosis (PTB) in a teaching hospital in Bauchi, northeast Nigeria. The aim of this study is to determine the sero-prevalence of HIV among patients with sputum smear positive PTB at Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH), Bauchi, Bauchi State, Nigeria. This is a retrospective study review of patients’ medical records diagnosed with sputum smear positive PTB that attended and received treatment at directly observed treatment short course (DOTS) clinic of Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH), Bauchi, Bauchi State, North-Eastern Nigeria from January, 2015- December, 2017. All the patients were newly diagnosed with sputum smear positive PTB using ZN stain testing of their sputum and screened for HIV antibodies. There were 155 patients studied comprising of 95 (61.29%) males and 60 (38.71%) females. One hundred and twenty (77.42%) patients were seronegative and 35 (22.58%) sero-positive for HIV. Most of the patients were within the ages of 15-54 years with mean age of 34.63±15.55. The sero-prevalence of HIV infection among the patients is 22.58%. Sero-prevalence of HIV is observed to be high among young and married patients with secondary level of education. The sero-prevalence of HIV infection among the patients is relatively lower than those reported in most parts of Nigeria and the sub-Saharan Africa, hence there is still need for continued screening of HIV antibodies among patients with PTB so as to reduce the morbidity and mortality that may result from the coinfection.

2018 ◽  
Vol 29 (14) ◽  
pp. 1400-1406
Author(s):  
Zahra Hasan ◽  
Sharaf Shah ◽  
Rumina Hasan ◽  
Shoaib Rao ◽  
Manzoor Ahmed ◽  
...  

Human immunodeficiency virus (HIV) infection prevalence in Pakistan has been increasing in high-risk groups, including people who inject drugs (PWID) and transgender hijra sex workers (TG-HSWs) nationwide. Effective control of HIV requires early diagnosis of the infection. We investigated recency of HIV infections in newly-diagnosed cases in PWID and TG-HSWs. This was an observational study with convenience sampling. Overall, 210 HIV-positive subjects comprising an equal number of PWID and TG-HSWs were included. Antibody avidity was tested using the Maxim HIV-1 Limiting Antigen Avidity (LAg) EIA (Maxim Biomedical, Inc. Rockville, Maryland, USA). The mean age of study subjects was 29.5 years: PWID, 28.5 years and TG-HSWs, 30.4 years. Study subjects were married, 27%, or unmarried. Eighteen percent of individuals had recently-acquired HIV infections: 19% of PWID and 17% of TG-HSWs. Eighty-two percent of individuals had long-term HIV infections: 81% of PWID and 83% of TG-HSWs. This is the first study identification of recent HIV-1 infections in Pakistan. We show that most newly-diagnosed HIV patients in the high-risk groups studied had long-term infections. There is an urgent need for intervention in these groups to facilitate early diagnosis and treatment of HIV infection to reduce transmission in Pakistan.


Author(s):  
Eihab Subahi ◽  
safwan aljafar ◽  
haidar barjas ◽  
Mohamed Abdelrazek ◽  
Fatima Rasoul

Opportunistic infections are common in human immunodeficiency virus (HIV)-infected patients. Co-infections with Cryptococcus neoformans together with Mycobacterium and Pneumocystis jiroveci pneumonia (PCP) are rare, and typically occur in immunocompromised individuals, particularly AIDS patients.


2017 ◽  
Vol 15 (1) ◽  
pp. 24-28
Author(s):  
Madhu Gyawalee ◽  
BP Paudyal ◽  
DB Pokhrel

Introduction: Sexually transmitted infections (STIs) are a major cause of public health problem. In developing countries, human immunodeficiency virus (HIV) infection is spreading rapidly, with sexually transmitted infections acting as a cofactor for the spread of HIV. Yet adequate awareness regarding these infections is lacking.Objective: To explore the knowledge and awareness about STIs and HIV infection in patients visiting Dermatology and Venereology Clinic of Institute of Medicine, Tribhuvan University Teaching Hospital (TUTH) with genital symptoms.Material and Methods: A cross sectional descriptive study was carried out in the department of dermato-venereology, TUTH for a period of one year. Total of 130 consecutive cases were enrolled. After taking consent and assuring confidentiality they were interviewed regarding awareness of STIs and HIV/AIDS.Results: Out of 130 cases, 95% and 98.5% had heard of an STI and HIV/AIDS respectively. Only 43.8% could mention discharge from genitalia as a symptom of STI whereas 38.5% could mention none. Most (91.5%) knew about the sexual mode of transmission of both STIs and HIV. None could mention about mother to child transmission of an STI, whereas 15% knew that an infected mother can transmit HIV to her baby. About 58% were aware that condoms could protect them from acquiring an STI, 63% perceived this as best method of prevention from HIV. When only 26% knew that being faithful to one partner is the best mode of prevention from an STI, 45% mentioned avoiding contact with multiple partners could prevent them from HIV transmission.Conclusions: Awareness programme on STIs as a whole could improve knowledge and awareness on HIV and STIs and hence prevent both.


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