scholarly journals Atrial septal aneurysm in Sub-Saharan Africa: From an asymptomatic incidental echocardiographic finding to a potential cause of cardio embolic stroke

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Raphael Anakwue ◽  
Angel-Mary Anakwue
Keyword(s):  
Incidental Finding ◽  
Interatrial Septum ◽  
Sub Saharan Africa ◽  
Cardioembolic Stroke ◽  
Atrial Septal Aneurysm ◽  
Echocardiographic Finding ◽  
First Case ◽  
Sub Saharan ◽  
High Index Of Suspicion ◽  
Cardiac Diagnosis

Atrial Septal Aneurysm (ASA) is an abnormality of the interatrial septum that has continued to generate interest because of its rarity, asymptomatic presentation and possibility to cause cardioembolic stroke. There are many published accounts of atrial septal aneurysm in USA, Europe and Asia but very few published reports from sub-Saharan Africa. Our first case is a 48 years old female patient with type 1 ASA presented as an incidental finding during echocardiographic investigative procedures for other cardiac diagnosis. The second case is a 58 years old female with type 2L ASA, who presented with transient loss of consciousness lasting for 5 minutes. Our third case is a 25 years old male with type 5 ASA with heart failure who presented with exertional dyspnoea for 3 years. In this presentation, we ask questions about the reason for rare presentations and or publications of atrial septal aneurysm from Africa. We also re-examined the different associations of ASA as well as clinical presentations. ASA is an often asymptomatic but treatable cause of cardiovascular disease that includes cardioembolic stroke. A high index of suspicion is required to make the diagnosis during routine trans thoracic echocardiography and the availability of transesophageal echocardiography will definitely improve diagnosis and management of cases in sub-Saharan Africa.

scholarly journals SARS-COV-2 induced Parkinsonism: The first case from the sub-Saharan Africa

2021 ◽  
pp. 100116
Author(s):  
Biniyam A. Ayele ◽  
Hanna Demissie ◽  
Meron Awraris ◽  
Wondwossen Amogne ◽  
Ali Shalash ◽  
...  
Keyword(s):  
Sub Saharan Africa ◽  
First Case ◽  
Sub Saharan

A critical analysis of water PPP failures in sub-Saharan Africa

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Salman Tariq ◽  
Xueqing Zhang
Keyword(s):  
Construction Management ◽  
Design Methodology ◽  
Sub Saharan Africa ◽  
African Countries ◽  
Content Type ◽  
Rigorous Approach ◽  
First Case ◽  
Management Perspective ◽  
Sub Saharan

PurposeTop-down pressure from donors, public sector inefficiencies and fund deficits have steered the introduction of public–private partnerships (PPPs) in sub-Saharan Africa. However, PPP activities in the water sector have been quite insignificant compared to other infrastructure sectors in this region. In addition, a number of water PPPs have encountered great difficulties and subsequent failures. This study aims at unveiling the underlying reasons behind failures.Design/methodology/approachThis study has classified the failure types of water PPPs and reviewed the development of water PPPs in sub-Saharan Africa to identify failed ones. Eight failed case studies are completed through the rigorous approach of event sequence mapping.FindingsNine root causes of water PPP failure are identified through a thorough examination of these failed water PPP cases and the interrelationships between these failure causes are established. The failure causes are further generalized through literature focusing on water PPP failures in developing countries and problematic issues that hinder the implementation of successful water PPPs across different Sub-Saharan African countries. Recommendations are provided for future improvements in carrying out water PPPs in Sub-Saharan Africa by learning past lessons and drawing experiences.Originality/valueThis is the first case study on water PPP failures in Sub-Saharan Africa from a construction management perspective. This study will help governments and the private sector in developing stronger future water PPPs.

scholarly journals Imported bancroftian filariasis discovered in a patient infected with Plasmodium falciparum: First case of concomitant parasitism in the Al-Buraimi Governorate, Oman

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Muhammad Muqeet Ullah ◽  
Ahmed Yar Mohammed Dawood Al Balushi ◽  
Nader Rahid Salim Al Aliyani ◽  
Biju Kalarikkal ◽  
Reeher Ian C. Miranda ◽  
...  
Keyword(s):  
Wuchereria Bancrofti ◽  
Sub Saharan Africa ◽  
Global Burden ◽  
Bancroftian Filariasis ◽  
African Region ◽  
Laboratory Findings ◽  
Anopheles Species ◽  
First Case ◽  
Nigerian Woman ◽  
Sub Saharan

Malaria and lymphatic filariasis (LF) are endemic in tropical and subtropical regions of sub-Saharan Africa, Asia, and Central and South America. Ninety-two percent (200 million) of malaria cases in 2017 were detected in the WHO African Region. This accounts for approximately 30% of the global burden of LF disease and includes 405.9 million people at risk in 39 out of 46 member countries. Anopheles species of mosquitoes transmit Wuchereria bancrofti in most parts of Africa. Our case of a 23-year-old Nigerian woman highlights incidental laboratory findings showing the first malaria/filariasis coinfection in the governorate (province). This coinfection was ascertained during the usual medical screening before recruitment in Oman, which is routinely conducted for every expatriate.

scholarly journals Ten-year plateau phase in human immunodeficiency virus induced motor neuron disease upon antiretroviral therapy: a first case from Eastern Africa.

2020 ◽  
Vol 1 (5) ◽  
pp. 29-32
Author(s):  
Marjolein De Bruin ◽  
Emmanuel Assay ◽  
Asha Osman ◽  
Kajiru Kilonzo ◽  
William Howlett ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Case Report ◽  
Antiretroviral Therapy ◽  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Sub Saharan Africa ◽  
Eastern Africa ◽  
First Case ◽  
Immunodeficiency Virus ◽  
Sub Saharan

We report an individual with rapidly progressive motor neuron disease (MND), phenotypically compatible with amyotrophic lateral sclerosis (ALS). The patient described in this case report proved positive for human immunodeficiency virus (HIV) and was initiated on antiretroviral therapy (ART). Following ART he clinically stabilised over 10 years and deteriorated again due to noncompliance or ART resistance. HIV infection can give rise to an MND mimic, HIV-ALS. The improvement in response to ART supports the notion that HIV-ALS is a treatable entity also in Africa. This is the first case report of a patient with HIV-ALS and long term follow up in Sub-Saharan Africa. The report raises the suggestion that an additional (retro)virus can play a role in the aetiology of ALS.

scholarly journals Sub-Saharan Africa preparedness and response to the COVID-19 pandemic: A perspective of early career African scientists

2020 ◽  
Vol 5 ◽  
pp. 163
Author(s):  
Gisele Umviligihozo ◽  
Lucy Mupfumi ◽  
Nelson Sonela ◽  
Delon Naicker ◽  
Ekwaro A. Obuku ◽  
...  
Keyword(s):  
Public Health ◽  
Case Fatality ◽  
Early Career ◽  
Health Interventions ◽  
Sub Saharan Africa ◽  
Public Health Interventions ◽  
African Countries ◽  
Scientific Publications ◽  
First Case ◽  
Sub Saharan

Emerging highly transmissible viral infections such as SARS-CoV-2 pose a significant global threat to human health and the economy. Since its first appearance in December 2019 in the city of Wuhan, Hubei province, China, SARS-CoV-2 infection has quickly spread across the globe, with the first case reported on the African continent, in Egypt on February 14th, 2020. Although the global number of COVID-19 infections has increased exponentially since the beginning of the pandemic, the number of new infections and deaths recorded in African countries have been relatively modest, suggesting slower transmission dynamics of the virus on the continent, a lower case fatality rate, or simply a lack of testing or reliable data. Notably, there is no significant increase in unexplained pneumonias or deaths on the continent which could possibly indicate the effectiveness of interventions introduced by several African governments. However, there has not yet been a comprehensive assessment of sub-Saharan Africa’s (SSA) preparedness and response to the COVID-19 pandemic that may have contributed to prevent an uncontrolled outbreak so far. As a group of early career scientists and the next generation of African scientific leaders with experience of working in medical and diverse health research fields in both SSA and resource-rich countries, we present a unique perspective on the current public health interventions to fight COVID-19 in Africa. Our perspective is based on extensive review of the available scientific publications, official technical reports and announcements released by governmental and non-governmental health organizations as well as from our personal experiences as workers on the COVID-19 battlefield in SSA. We documented public health interventions implemented in seven SSA countries including Uganda, Kenya, Rwanda, Cameroon, Zambia, South Africa and Botswana, the existing gaps and the important components of disease control that may strengthen SSA response to future outbreaks.

scholarly journals First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Yannick M. Nlandu ◽  
Jean-Robert R. Makulo ◽  
Nestor M. Pakasa ◽  
Ernest K. Sumaili ◽  
Clarisse N. Nkondi ◽  
...  
Keyword(s):  
Coming Out ◽  
Negative Impact ◽  
Kidney Injury ◽  
Sub Saharan Africa ◽  
Collapsing Glomerulopathy ◽  
First Case ◽  
Out Of Africa ◽  
Sub Saharan ◽  
Glomerular Involvement ◽  
New Onset

Although the lungs remain the main target of SARS-CoV-2, other organs, such as kidneys, can be affected, which has a negative impact on the outcomes of COVID-19 patients. Although previous studies of kidney disease in COVID-19 reported mainly SARS-CoV-2-induced tubular and interstitial injury, there is growing evidence coming out of Africa of glomerular involvement, especially collapsing glomerulopathy seen particularly in people of African descent. We report a case of collapsing glomerulopathy revealed by acute kidney injury and a new onset of full blown nephrotic syndrome in a black Congolese patient coinfected with COVID-19 and malaria.

scholarly journals Diagnosis of Cryptococcosis and Prevention of Cryptococcal Meningitis Using a Novel Point-of-Care Lateral Flow Assay

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Ashar Dhana
Keyword(s):  
Cryptococcal Meningitis ◽  
Point Of Care ◽  
World Health Organisation ◽  
Lateral Flow ◽  
Sub Saharan Africa ◽  
World Health ◽  
First Case ◽  
Lateral Flow Dipstick ◽  
Life Threatening ◽  
Sub Saharan

Despite access to antiretroviral therapy, mortality from cryptococcal meningitis (CM) is high among persons with advanced HIV infection in sub-Saharan Africa. Cryptococcal antigen (CrAg) is present several weeks to months before the onset of symptoms of meningitis and can be screened to prevent life threatening meningitis. Recently, the World Health Organisation recommended that a new rapid CrAg lateral flow ‘‘dipstick’’ assay (LFA) is to be used to screen HIV-infected persons with CD4 counts of less than 100 cells/µL. In this paper, we describe two cases of cryptococcosis with differing outcomes. In the first case, the new CrAg LFA was used as part of a screen and preemptive treatment strategy to prevent CM. In the second case, our patient had no access to the CrAg LFA and subsequently developed life threatening meningitis. To the best of our knowledge, this is the first case report of cryptococcosis diagnosed using this novel assay.

scholarly journals A Giant Egg-like symptomatic Loose Body in the Peritoneal Cavity: A Case Report

1970 ◽  
Vol 29 (6) ◽  
Author(s):  
Berhanetsehay Teklewold ◽  
Anteneh Kehaliw ◽  
Melat Teka ◽  
Bereket Berhane
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Incidental Finding ◽  
Loose Body ◽  
Loose Bodies ◽  
Diagnostic Challenge ◽  
First Case ◽  
Appendices Epiploicae ◽  
The One ◽  
High Index Of Suspicion

Background: Peritoneal loose bodies are rare lesions that are usually found as an incidental finding during abdominal surgery. Large loose bodies, measuring more than 5 cm, are rare and only a few cases are reported in the literature. Peritoneal loose bodies are usually infarcted appendices epiploicae, which become detached and appear as a peritoneal loose body in the abdominal cavity.Case Presentation: We report here the first case, in the local Ethiopian context, of a giant “egg-like” loose peritoneal body measuring 7 × 6 cm found in a 50-year-old man who presented with a cramping abdominal pain and features of abdominal obstruction. The current hypothesis as regards these bodies and the diagnostic challenges is discussed.Conclusion: Small peritoneal loose bodies are common but giant and symptomatic ones’, like the one discussed here, are very rare and a diagnostic challenge. And, in the context of intestinal obstruction, a high index of suspicion is needed in order to diagnose them.

scholarly journals Cor triatriatum sinister in a 36-Year-old male with Metabolic Syndrome: A case report in sub-Saharan Africa.

2021 ◽  
Author(s):  
Ahmadou Jingi ◽  
Liliane Mfeukeu-Kuate ◽  
Sylvie Ndongo ◽  
Edvine Guela-Wawo
Keyword(s):  
Metabolic Syndrome ◽  
Congenital Heart Disease ◽  
Case Report ◽  
Congenital Heart ◽  
Sub Saharan Africa ◽  
Cor Triatriatum ◽  
Mitral Valve Stenosis ◽  
First Case ◽  
Cor Triatriatum Sinister ◽  
Sub Saharan

We report the first case of isolated Cor triatriatum sinister in a 36-year-old male with metabolic syndrome in sub-Saharan Africa. It is a rare congenital heart disease that consists of a fibromuscular ring that divides the atrium into two chambers. It can mimic mitral valve stenosis.

Effects of Colonialism from the Perspective of Craniofacial Variation

2017 ◽  
Author(s):  
Isabelle Ribot ◽  
Alan G. Morris ◽  
Emily S. Renschler
Keyword(s):  
Sub Saharan Africa ◽  
Second Generation Immigrants ◽  
First Case ◽  
Sub Saharan ◽  
Craniometric Variation ◽  
First And Second Generation ◽  
Population Affinity ◽  
Craniofacial Variation ◽  
Presence Of People

Ribot, Morris, and Renschler compare two distinct case studies of Africans in order to investigate identity, origin, and population affinity of diasporic populations. In the first case study from Cobern Street in Cape Town, South Africa, the authors integrate stable isotope data and burial data with craniometric variation. In the second case, craniometric data are studied in a sample of Africans from the Morton Collection derived from a group of enslaved people brought to Colonial Cuba. In the Cobern Street setting, they find evidence of both first and second-generation immigrants or imported slaves from sub-Saharan Africa, as well as the possible presence of people of Asian descent (either slaves or immigrants). In contrast with the Cobern Street case study, Ribot and colleagues find high levels of diversity represented in the Morton sample, with some individuals from a single origin within Central, West, or East Africa, some individuals exhibiting multiple possible African origins, and finally, some other individuals exhibiting complex patterns of heterogeneity which may reflect origins and admixture from Asia, Europe, or Mesoamerica.

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