scholarly journals Complementary use of topical bitter melon for atopic dermatitis

2012 ◽  
Vol 2 (1) ◽  
pp. 7 ◽  
Author(s):  
Dai Park ◽  
Nguyen P. Tran ◽  
Jerald M. Duncan ◽  
D. Betty Lew
Keyword(s):  
Atopic Dermatitis ◽  
Traditional Medicine ◽  
Complementary Medicine ◽  
Clinical Studies ◽  
Skin Disorder ◽  
Momordica Charantia ◽  
Bitter Melon ◽  
Community Interest ◽  
Comparison Trial ◽  
Pruritic Skin

<em>Momordica charantia</em> (bitter melon) is popular in systems of traditional medicine to treat a variety of diseases including atopic dermatitis, which is an inflammatory, chronically relapsing skin disorder characterized by dry, scaly, pruritic skin. While there is growing community interest in adopting bitter melon as a complementary medicine, there are no clinical studies looking at its use for atopic dermatitis. Here we report a case of a 6-yearold female with severe refractory atopic dermatitis that responded to treatment with topical bitter melon in an open half-side comparison trial.

Comparison of Biological Activities of Ethanol Extracts of Unripe Fruit of Bitter Melon (Momordica charantia L.) Cultivated in Hamyang, Korea

2015 ◽  
Vol 44 (11) ◽  
pp. 1637-1644 ◽  
Author(s):  
Jeong-Han Moon ◽  
Dong-Won Choi ◽  
Seong-Eun Kim ◽  
Ji-Hoon Seomoon ◽  
Su-Young Hong ◽  
...  
Keyword(s):  
Biological Activities ◽  
Momordica Charantia ◽  
Bitter Melon ◽  
Unripe Fruit ◽  
Ethanol Extracts

Remission of Alopecia Universalis after 1 Year of Treatment with Dupilumab in a Patient with Severe Atopic Dermatitis

2021 ◽  
pp. 1-4
Author(s):  
Maurizio Romagnuolo ◽  
Mauro Barbareschi ◽  
Simona Tavecchio ◽  
Luisa Angileri ◽  
Silvia Mariel Ferrucci
Keyword(s):  
Atopic Dermatitis ◽  
Skin Disorder ◽  
Human Monoclonal Antibody ◽  
Severe Atopic Dermatitis ◽  
T Helper ◽  
T Helper 1 ◽  
Th2 Response ◽  
Alopecia Universalis ◽  
T Helper 2 ◽  
Relapsing Remitting

Alopecia areata (AA), an autoimmune disease with a relapsing-remitting course, represents the second cause of non­scarring alopecia worldwide and is associated with several comorbidities, notably atopic dermatitis (AD). In particular, AD is related to its more severe forms alopecia totalis (AT) and alopecia universalis (AU) [Nat Rev Dis Primers. 2017;3:17011]. Considering that AA has been classified as T helper 1-driven disease, whereas AD is the prototypical T helper 2 (Th2)-driven skin disorder, recent studies suggest that these forms may underlie a different chemokine expression resulting in a Th2 skewing as a key pathomechanism that could explain this association [JAMA Dermatol. 2015 May;151(5):522–8]. Several reports showed that dupilumab, a fully human monoclonal antibody targeting the interleukin 4α receptor and thus downregulating Th2 response, led to an improvement of AA associated with AD; most of these patients were females with AT or AU, early-onset AD, and atopic comorbidities [Exp Dermatol. 2020 Aug;29(8):726–32]. We report here a case to further support this hypothesis.

scholarly journals Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade

2016 ◽  
Vol 15 (3) ◽  
pp. 376-389 ◽  
Author(s):  
Mingo M. H. Yung ◽  
Fiona A. Ross ◽  
D. Grahame Hardie ◽  
Thomas H. Y. Leung ◽  
Jinbiao Zhan ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Cisplatin Resistance ◽  
Momordica Charantia ◽  
Signaling Cascade ◽  
Ovarian Cancer Cells ◽  
Bitter Melon ◽  
Ampk Signaling

Wild bitter melon (Momordica charantia Linn. var. abbreviata Ser.) extract and its bioactive components suppress Propionibacterium acnes-induced inflammation

2012 ◽  
Vol 135 (3) ◽  
pp. 976-984 ◽  
Author(s):  
Chin Hsu ◽  
Tsung-Hsien Tsai ◽  
You-Yi Li ◽  
Wen-Huey Wu ◽  
Ching-Jang Huang ◽  
...  
Keyword(s):  
Propionibacterium Acnes ◽  
Momordica Charantia ◽  
Bitter Melon ◽  
Bioactive Components

scholarly journals Bitter melon (Momordica charantia) attenuates atherosclerosis in apo-E knock-out mice possibly through reducing triglyceride and anti-inflammation

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Yanmei Zeng ◽  
Meiping Guan ◽  
Chenzhong Li ◽  
Lingling Xu ◽  
Zhongji Zheng ◽  
...  
Keyword(s):  
Momordica Charantia ◽  
Bitter Melon ◽  
Knock Out ◽  
Apo E ◽  
Knock Out Mice ◽  
Anti Inflammation

scholarly journals Additives Promote Adventitious Buds Induction from Stem Segments of Bitter Melon (Momordica charantia L.)

2011 ◽  
Vol 3 (2) ◽  
Author(s):  
Yi Tang ◽  
Ji Liu ◽  
Bin Liu ◽  
Xiaomei Li ◽  
Juan Li ◽  
...  
Keyword(s):  
Momordica Charantia ◽  
Bitter Melon ◽  
Adventitious Buds ◽  
Stem Segments
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