scholarly journals Acral perineurioma: a case report of a rare neoplasm successfully treated with autologous skin graft reconstructive surgery

2021 ◽  
Author(s):  
Elena Pierobon ◽  
Chiara Cortelazzi ◽  
Michele Maria Dominici ◽  
Claudio Feliciani ◽  
Sergio Di Nuzzo
Keyword(s):  
Skin Graft ◽  
Functional Recovery ◽  
Reconstructive Surgery ◽  
Soft Tissues ◽  
Subcutaneous Tissue ◽  
Benign Neoplasm ◽  
Surgical Excision ◽  
Large Mass ◽  
Nerve Sheath Tumor ◽  
Complete Surgical Excision

Soft tissues perineurioma is a rare nerve sheath tumor that affects most of all the subcutaneous tissue. Even if it could present as a large mass, it is a benign neoplasm for whom a complete surgical excision represents the gold standard treatment. Considering that it usually affects acral sites of young people, can be challenging to perform a reconstructive surgery that allows a full functional recovery. We report the case of a woman in her 20s presenting a perineurioma of the sole of the foot, a nodule of about 2 cm of diameter that compromised the support of the foot on the ground. We performed a radical surgical excision with no recurrence after 3 years of follow up and we obtained a full functional recovery thanks to an autologous full-thickness skin graft.

scholarly journals Retroperitoneal pelvic schwannoma in pregnancy: a case report

2017 ◽  
Vol 6 (8) ◽  
pp. 3689 ◽  
Author(s):  
Nithya J. ◽  
Banumathy M. ◽  
Radha A.
Keyword(s):  
Spindle Cell ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Nerve Sheath Tumor ◽  
Ct Guided ◽  
Spindle Cell Neoplasm ◽  
Complete Surgical Excision ◽  
S 100 ◽  
Needle Aspiration Cytology ◽  
In Pregnancy

Solitary nerve sheath tumor such as Benign schwannomas arising in the pelvic retro peritoneum is infrequently reported. Retroperitoneal location accounts for 0.3-3.2% of primary schwannomas. We report a case of benign retroperitoneal pelvic schwannoma in pregnancy that was incidentally diagnosed when it presented with Preterm premature rupture of membranes and mechanical obstruction for labour. She underwent caesarean section and delivered a healthy baby. She was evaluated in the postoperative period by computerized tomography (CT) imaging studies and CT guided fine needle aspiration cytology (FNAC) was not diagnostic. Complete surgical excision of the tumor was achieved in the postpartum period. The adjacent vascular and urinary channels sustained no injuries and she had no neurologic deficit. Histology revealed spindle cell neoplasm composed of interlacing fascicles and sheets of spindle cell with focal areas of nuclear palisading and thick walled blood vessels. Immunohistochemistry was positive for S 100 suggesting schwannoma. Retroperitoneal location of schwannomas is rare and surgery is curative. Prognosis is good, since recurrence is rare. 

scholarly journals A 15-year mystery resolved: a large bone-boring glomus tumor mistaken as dermatitis

2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Sarah Bouayyad ◽  
Mohamed Abdelaty ◽  
Anuj Mishra
Keyword(s):  
Glomus Tumor ◽  
Benign Neoplasm ◽  
Surgical Excision ◽  
Clinical Tests ◽  
Cold Intolerance ◽  
X Ray ◽  
Complete Surgical Excision ◽  
Large Bone ◽  
Paroxysmal Pain

Abstract Glomus tumor (GT) is a rare, benign neoplasm of the glomus apparatus. Being most common in the subungual region, it often misdiagnosed with dermatological conditions. Severe tenderness, paroxysmal pain and cold intolerance symptomatically denote GT. Clinical tests such as Love’s pin test and Hildreth’s test assist in diagnosing the disease. X-ray, ultrasonography and magnetic resonance imaging can confirm the severity of the lesion. Complete surgical excision is the only treatment available for these subcutaneous nodules. A middle-aged male with a hand pain, who misdiagnosed for dermatitis over 15-year period, has identified as having a large bone-boring GT. Awareness of GT among healthcare professionals is a must to increase the quality of life of patients.

scholarly journals Epidermal Inclusion Cyst Presenting as a Palpable Scrotal Mass

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Andres F. Correa ◽  
Bishoy A. Gayed ◽  
Mitchell E. Tublin ◽  
Anil V. Parwani ◽  
Jeffrey R. Gingrich
Keyword(s):  
Subcutaneous Tissue ◽  
Surgical Excision ◽  
Rare Entity ◽  
Median Raphe ◽  
Inclusion Cyst ◽  
Scrotal Mass ◽  
Medial Thigh ◽  
Complete Surgical Excision ◽  
Epidermal Inclusion Cyst ◽  
Median Raphé

We report a scrotal epidermal inclusion cyst located outside the median raphe which a rare entity in the absence of trauma and few cases have been reported. 47 year old male presents with a complaint of right sided testicular swelling and discomfort. On examination a 3 cm mass was palpated between the scrotum and the medial thigh on the subcutaneous tissue with a positive slip sign. Complete surgical excision of the cyst was performed. Histopathology confirmed epidermal inclusion cyst with no evidence of malignancy.

scholarly journals Clear cell sarcoma of the nuchal region with metastasis in stomach

2011 ◽  
Vol 19 (3-4) ◽  
pp. 76-78
Author(s):  
Dragana Tegeltija ◽  
Aleksandra Lovrenski ◽  
Milana Panjkovic ◽  
Slavica Knezevic-Usaj ◽  
Zivka Eri ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Soft Tissues ◽  
Clear Cell ◽  
Neck Region ◽  
Surgical Excision ◽  
Clear Cell Sarcoma ◽  
Lower Limbs ◽  
Medical Attention ◽  
Cell Sarcoma ◽  
Complete Surgical Excision

Clear cell sarcoma/malignant melanoma of soft parts is a rare malignant tumor that originates from the neural crest. It is most common in young men in the lower limbs, grows slowly in the form of deep localized nodes around the tendons, fascia, and aponeurosis. Prognosis is poor, local recurrences and metastases are common. We present a case of a 53-year-old patient who sought medical attention due to the presence of a tumefaction in the nuchal neck region, followed by pain, heightened sensitivity, and numbness in his right hand. After excision, histological examination, and application of immunohistochemical and histochemical methods, malignant melanoma of soft tissues was diagnosed. Fourteen months after the excision of the neck tumor, a metastatic stomach disease was diagnosed. Larger tumors with necrosis, expressed pleomorphisam, and increased mitotic activity give metastases before local recurrence. Diagnosis is set using immunohistochemical methods after surgical excision of the tumor and the prognosis of the disease depends on the size of tumor and complete surgical excision.

Primary Leiomyosarcoma of the Pancreas

2001 ◽  
Vol 125 (1) ◽  
pp. 152-155
Author(s):  
Gabriella Nesi ◽  
Desiree Pantalone ◽  
Ilaria Ragionieri ◽  
Andrea Amorosi
Keyword(s):  
Smooth Muscle ◽  
World Literature ◽  
Soft Tissues ◽  
Malignant Tumors ◽  
Smooth Muscle Actin ◽  
Surgical Excision ◽  
High Rate ◽  
Complete Surgical Excision ◽  
Membrane Components ◽  
Primary Leiomyosarcoma

Abstract Primary leiomyosarcoma of the pancreas is a rare tumor for which only 21 reports appear in the world literature. We describe an additional case of pancreatic leiomyosarcoma in a 76-year-old man, who complained of persistent high fever. Histologic examination revealed a pleomorphic spindle cell tumor. Reactivity for muscle-specific actin, α-smooth muscle actin, and basement membrane components, along with negative staining for epithelial and neural markers, were consistent with a smooth muscle sarcoma. The patient died of disease 1 year after complete surgical excision. This report highlights the need to use a complete antibody panel in order to accurately immunophenotype pleomorphic malignant tumors of the pancreas. A review of the cases compiled in the literature indicates that pancreatic leiomyosarcoma, like its counterpart arising in deep soft tissues, is an aggressive neoplasm characterized by short survival and a high rate of metastases.

scholarly journals Conjunctival Myxoma: A Synopsis of a Rare Ocular Tumor

2015 ◽  
Vol 139 (5) ◽  
pp. 693-697 ◽  
Author(s):  
Meng-Jun Xiong ◽  
Daniel C. Dim
Keyword(s):  
Smooth Muscle Actin ◽  
Skin Pigmentation ◽  
S100 Protein ◽  
Benign Neoplasm ◽  
Surgical Excision ◽  
Clinical History ◽  
Carney Complex ◽  
Autosomal Dominant Disorder ◽  
Complete Surgical Excision ◽  
Conjunctival Myxoma

Conjunctival myxoma is an exceptionally rare, slow-growing, benign neoplasm of primitive mesenchyme origin. Forty-one cases of conjunctival myxoma from a literature review, including the authors' case, are listed. The usual clinical history is a painless mass appearing during months to years. Grossly, the tumor is a well-circumscribed, cystlike, gelatinous, yellow-to-pink, translucent-to-solid mass. Microscopically, the hypocellular tumor contains stellate- and spindle-shaped cells in a mucoid stroma with abundant hyaluronic acid mucopolysaccharides. Vimentin and α-smooth muscle actin highlight the spindle and stellate cells. S100 protein and desmin are negative for the tumor cells. Treatment is complete surgical excision, with no recurrence reported in the follow-up period. Notably, conjunctival myxoma may be associated with Carney complex, an autosomal-dominant disorder associated with skin pigmentation, endocrine abnormalities, and myxoma of the heart and eye. Physicians should appreciate this unique ocular tumor because of its potential association with Carney complex.

scholarly journals Radiographic, Citomorphological, and Histochemical Characterization of the Skin Mixosarcoma in a Bitch

2018 ◽  
Vol 47 ◽  
Author(s):  
Rubia Avlade Guedes Sampaio ◽  
Amabile Arruda De Souza e Silva ◽  
Telma De Sousa Lima ◽  
Alane Pereira Alves ◽  
Débora Ferreira Dos Santos Ângelo ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Subcutaneous Tissue ◽  
Present Report ◽  
Low Frequency ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Radiographic Examination ◽  
Neoplastic Cells ◽  
Biopsy Material ◽  
Complete Surgical Excision

Background: Myxosarcoma is a malignant mesenchymal tumor that arises from fibroblasts and is characterized by a low frequency of metastases, which in turn are highly invasive locally. Even though this type of tumor is relatively well documented, its radiographic and cytomorphological aspects are rarely described. The present report describes a case of cutaneous myxosarcoma in a female dog, and highlights radiographic, cytological, and histopathological findings.Case: An 11-year-old female mongrel dog was examined at the Veterinary Hospital of Federal University of Paraíba. The patient exhibited a firm 20 cm-wide mass covered by skin in the left abdominal wall, a lesion that had been developing for approximately five months. During the clinical examination, the patient demonstrated apathy and difficulty to stand. Initially, exams requested included radiography, ultrasonography, and cytological analysis of biopsy material obtained by fine needle aspiration (FNA). Radiography and ultrasonography were used to investigate the extent of the tumor, as well as invasion of other organs. Radiography revealed that the tumor was radiopaque, homogeneous, and restricted to the skin and subcutaneous tissue; no metastases were observed.  Cytological examination allowed observation of a hypocellular sample predominantly composed of isolated pleomorphic fusiform cells embedded in a discrete homogeneous eosinophilic material. These cells exhibited a moderate, well delimited cytoplasm with multiple vacuoles; the end opposed to the nucleus was slender.  Their nuclei were eccentric, with punctate chromatin and inconspicuous nucleoli.  The patient was subjected to complete surgical excision of the tumor, and the surgical piece was submitted to histopathological examination. The mass was described as single and firm; its dimensions were 20 cm x 16 cm x 15 cm, and its weight was 2.5 kg.  Fragments were processed and stained with hematoxylin and eosin (HE) or alcian blue (AB) for evaluation by optical microscopy. Histopathology revealed an infiltrative, expansive, non-encapsulated mass characterized by mesenchymal cells ranging from elongated to stellate. These cells were well individualized, had a scant to moderate cytoplasm, indistinct and slightly eosinophilic borders, and a nucleus that varied from oval to stellate in shape, with highly condensed chromatin and inconspicuous nucleoli. AB-stained specimens exhibited an extensive myxomatous matrix stained in blue, which was intertwined with neoplastic cells. Therefore, the diagnosis of cutaneous myxosarcoma was confirmed.Discussion: The diagnosis of myxosarcoma was established on the basis of radiographic and cytological findings, and it was confirmed by histopathological examination, which sped up decision-making and completion of the case.  Tumors of this group are not accompanied by paraneoplastic syndromes; however, given the size and weight of the mass under study, pain may have been the triggering factor of the apathy and difficulty to stand observed here. The age of the patient and the occurrence of the tumor in the skin are in agreement with the literature; however, presence of the tumor in the abdominal skin is uncommon, and this fact prevented definition of a clinical suspicion prior to cytopathological examination. Radiographic examination confirmed the dimensions and extent of the mass; additionally, it allowed exclusion of occurrence of metastatic foci. Cytologically, the material analyzed was consistent with literature findings for canine myxosarcoma samples, so that cytopathological examination already suggested occurrence of such condition in this case. Histopathological evaluation was indispensable for establishment of the diagnosis as well as AB staining, which highlighted high amounts of glycosaminoglycans among the neoplastic cells, which led to confirmation of the diagnosis.

INTRAOSSEOUS ANGIOLIPOMA OF THE CRANIUM

Neurosurgery ◽  
2009 ◽  
Vol 64 (1) ◽  
pp. E189-E190 ◽  
Author(s):  
Kenny Yu ◽  
James Van Dellen ◽  
Philip Idaewor ◽  
Federico Roncaroli
Keyword(s):  
Clinical Presentation ◽  
Subcutaneous Tissue ◽  
Rare Condition ◽  
Surgical Excision ◽  
Benign Tumors ◽  
Complete Surgical Excision ◽  
History Of ◽  
Titanium Cranioplasty ◽  
Intraosseous Lesion ◽  
Slow Growing

Abstract OBJECTIVE We describe an intraosseous angiolipoma of the cranium and discuss the outcome. Angiolipomas are benign tumors that consist of mature adipose tissue and abnormal vessels. They occur predominantly in the subcutaneous tissue of the trunk and upper limbs. Only 4 examples of intraosseous angiolipomas have been reported in the literature, all of which involved the mandible and ribs. CLINICAL PRESENTATION A 39-year-old man presented with a right parietal swelling. The patient initially refused surgery; thus it was possible to follow this case for 11 years, allowing us to evaluate the natural history of this rare condition. INTERVENTION Complete surgical excision of the intraosseous lesion was achieved with a titanium cranioplasty performed at intervals. Fifteen months after surgery, no recurrence was seen. CONCLUSION This is the first known report of intraosseous angiolipoma of the cranium. Angiolipomas are rare, benign, slow-growing tumors with an excellent prognosis. On preoperative neuroimaging, they may mimic intraosseous angiomas, lipomas, or intraosseous meningiomas. Total resection is curative.

Intraneural Nodular Fasciitis of the Dorsal Scapular Nerve: Case Report and Review of the Literature

2021 ◽  
Author(s):  
Ivan Domazet ◽  
Niko Njiric ◽  
Antonia Jakovcevic ◽  
Andrija Bitunjac ◽  
Krešimir Domazet ◽  
...  
Keyword(s):  
Case Report ◽  
Subcutaneous Tissue ◽  
Benign Neoplasm ◽  
Surgical Excision ◽  
Left Shoulder ◽  
Nodular Fasciitis ◽  
History Of ◽  
Magnetic Resonance Imaging Mri ◽  
Histopathologic Analysis ◽  
Rare Diagnosis

Abstract Background Nodular fasciitis is a benign neoplasm occurring predominantly in the subcutaneous tissue. There have been nine intraneural occurrences described in the literature. Case report A 37-year-old woman presented with numbness and tenderness in her left shoulder and scapula and a slightly dropped left shoulder, without history of trauma. A magnetic resonance imaging (MRI) of the cervical spine showed a well-circumscribed oval mass deep to the levator scapula muscle. Due to persisting symptoms and an unknown nature of the process, surgical excision was performed, and histopathologic analysis confirmed diagnosis of a benign fibroblastic/myofibroblastic neoplasm, nodular fasciitis. The postoperative course was uneventful and the patient was without symptoms at 4 months of follow-up. Methods We reviewed the available literature (PubMed, Google Scholar), with nine published cases of intraneural nodular fasciitis. The reported clinical, radiologic, and histopathologic parameters were evaluated and compared. Discussion Most of the cases reported in the literature were symptomatic, with tenderness and palpability being the main symptoms. Six of the reported cases occurred in the forearm, whereas three were in the leg. To the best of our knowledge, ours is the first reported case of nodular fasciitis occurring in the trunk. Ours is the only case to display desmin positivity, which supports the reactive hypothesis of nodular fasciitis. Conclusion Intraneural nodular fasciitis is an extremely rare diagnosis. Due to its benign natural course, a multidisciplinary approach with this extremely rare diagnosis in mind is needed to avoid overtreatment.

scholarly journals Atypical presentation and management of an epithelioid hemangioma: a case report and review of the literature

2020 ◽  
Vol 16 (1) ◽  
Author(s):  
Claire J. Wiggins ◽  
Rami P. Dibbs ◽  
Erica L. Bartlett ◽  
Daniel J. Ashton ◽  
Renata S. Maricevich
Keyword(s):  
Subcutaneous Tissue ◽  
Pediatric Population ◽  
Neck Region ◽  
Surgical Excision ◽  
Vascular Lesion ◽  
Vascular Anomalies ◽  
Preoperative Embolization ◽  
Epithelioid Hemangioma ◽  
Recommended Treatment ◽  
Complete Surgical Excision

Abstract Background Epithelioid hemangioma is a rare, benign vascular lesion classically presenting with painless nodules in the head and neck region. Hemangioma lesions are typically small, located within the dermis and subcutaneous tissue, and rarely exceed 10 cm in size. Complete surgical excision, with negative margins, is the recommended treatment as local recurrence is common. We describe an unusual presentation of epithelioid hemangioma that, to our knowledge, has not been previously described in the literature, epithelioid. Case presentation We report an atypical case of a large epithelioid hemangioma lesion with deep intramuscular involvement in a 16-year-old male. Ultrasound and MRI showed a hypervascular mass on the patient’s left upper back, and biopsy confirmed the diagnosis. Treatment consisted of preoperative embolization followed by excision and local tissue rearrangement. Conclusions Epithelioid hemangiomas are considered uncommon in the pediatric population. Moreover, it is challenging to diagnose these lesions due to their similarities to other vascular anomalies. We aim to increase awareness of this condition and obtain more precision in diagnosis, thus standardizing the approach for those treating individuals with vascular anomalies.

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