Fosfomycin, a therapeutic option for infections produced by multiple drug-resistant Enterobacteriaceae
Due to the increasing prevalence of infections caused by resistant bacteria and especially multiple drug resistance <em>Enterobacteriaceae</em>, availability of alternative effective antibiotics is restricted. The goal of this study was to investigate the susceptibility profile of multiple drug resistance and extensively drug resistance <em>Enterobacteriaceae</em> isolated from various clinical samples to fosfomycin. A total of 303 non-duplicate <em>Enterobacteriaceae</em> isolates were collected. Identification and susceptibility testing were done according to standard microbiological procedures and the Kirby-Bauer test, respectively. Of all isolates, 272 (89.8%) and 26 (8.6%) were detected as multiple drug resistance and extensively drug resistance strains, respectively. The most effective antibiotic (98%) was fosfomycin, when compared with other antibiotics against multiple drug resistance and extensively drug resistance <em>Enterobacteriaceae</em> isolates. In this study, we find high levels of resistance to commonly used antibiotics. However, fosfomycin can be a good option for treating multiple drug resistance <em>Enterobacteriaceae</em>.