scholarly journals CHARACTERISTICS OF PATIENTS HOSPITALIZED WITH 2009 H1N1 INFLUENZA IN A TERTIARY CARE HOSPITAL IN SOUTHERN SAUDI ARABIA

2012 ◽  
Vol 4 (1) ◽  
pp. e2012002 ◽  
Author(s):  
Adnan Agha ◽  
Abdul Qader Alrawi ◽  
Abdelhaleem Bella ◽  
Mohammed S. AlAyed
Keyword(s):  
Saudi Arabia ◽  
Influenza A ◽  
H1n1 Virus ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
H1n1 Influenza ◽  
Care Hospital ◽  
Influenza A H1n1 ◽  
2009 H1n1 ◽  
A Prospective Study

Background Pandemic influenza A (H1N1) virus emerged and spread globally in the spring of 2009.  We describe the clinical features of the patients who were hospitalized with 2009 H1N1 influenza July 2009 to June 2010 in a tertiary care hospital in Khamis Mushyt, Saudi Arabia.  We analyzed the clinical and laboratory variables in order to determine predictors of poor outcome Methods We performed a prospective study in all patients who were hospitalized for at least 48 hours  and with a positive test for 2009 H1N1 virus through RT-PCR(real time polymerase chain reaction).  Their epidemiological, clinical, biochemical characteristics were collected and the hospital course of the patients with eventual outcome (discharge or death) was observed. We applied a logistic regression analysis to determine the best predictor of death.

Pandemic 2009 Influenza A (H1N1) Virus among Japanese Healthcare Workers: Seroprevalence and Risk Factors

2012 ◽  
Vol 33 (1) ◽  
pp. 58-62 ◽  
Author(s):  
Yoko Nukui ◽  
Shuji Hatakeyama ◽  
Takatoshi Kitazawa ◽  
Tamami Mahira ◽  
Yoshizumi Shintani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Healthcare Workers ◽  
Influenza A ◽  
H1n1 Virus ◽  
Healthcare Personnel ◽  
Care Hospital ◽  
Occupational Risk Factors ◽  
Increased Risk ◽  
Influenza A H1n1 ◽  
2009 H1n1

Objective.To evaluate the seroprevalence and risk factors for 2009 influenza A (H1N1) virus infection among healthcare personnel.Design.Observational cross-sectional study.Patients and Setting.Healthcare workers (HCWs) in an acute care hospital.Methods.Between September 14 and October 4, 2009, before 2009 H1N1 vaccination, we collected serological samples from 461 healthy HCWs. Hemagglutination-inhibition antibody assays were conducted. To evaluate the risk factors of seropositivity for 2009 H1N1 virus, gender, age, profession, work department, usage of personal protective equipment, and seasonal influenza vaccination status data were gathered via questionnaires.Results.Our survey showed that doctors and nurses were at highest risk of seropositivity for the 2009 H1N1 virus (odds ratio [OR], 5.25 [95% confidence interval {CI}, 1.21–22.7]). An increased risk of seropositivity was observed among pediatric, emergency room, and internal medicine staff (adjusted OR, 1.98 [95% CI, 1.07–3.65]). Risk was also higher among HCWs who had high titers of antibodies against the seasonal H1N1 virus (adjusted OR, 1.59 [95% CI, 1.02–2.48]).Conclusions.Seropositivity for the 2009 H1N1 virus was associated with occupational risk factors among HCWs.Infect Control Hosp Epidemiol 2012;33(1):58-62

scholarly journals HRCT THORAX FINDINGS OF INFLUENZA A H1N1 PNEUMONIA IN A TERTIARY CARE HOSPITAL IN SOUTH INDIA

2017 ◽  
Vol 4 (52) ◽  
pp. 3167-3171
Author(s):  
Koushik Muthu Raja Mathivanan ◽  
Swetha Sasikumar ◽  
Gokulakrishnan Periakaruppan ◽  
Rajagopalan Balakrishnan ◽  
Uma Sekar
Keyword(s):  
Influenza A ◽  
South India ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Influenza A H1n1 ◽  
H1n1 Pneumonia

Hospitalized pandemic influenza A (H1N1) patients in a university hospital

Open Medicine ◽  
2011 ◽  
Vol 6 (1) ◽  
pp. 83-88 ◽  
Author(s):  
Gokhan Metan ◽  
Ilkay Bozkurt ◽  
Cigdem Agkus ◽  
Ramazan Coskun ◽  
Emine Alp ◽  
...  
Keyword(s):  
Influenza A ◽  
Medical Condition ◽  
Tertiary Care ◽  
Ventilatory Support ◽  
H1n1 Influenza ◽  
University Hospital ◽  
Central Anatolia ◽  
Care Hospital ◽  
Reactive Protein ◽  
Influenza A H1n1

AbstractThe purpose of this study was to describe the demographic and clinical features of hospitalized patients with the pandemic H1N1 influenza A virus infection in a tertiary care hospital in Central Anatolia, Turkey. The patients, all over 16 years of age and hospitalized for influenza-like symptoms between 1 November 2009 and 31 December 2009, were retrospectively identified from the records of the Infectious Diseases Department. Eighty patients whose diagnoses were confirmed by real-time PCR were included in this study. The median age of the patients was 27 years; 41 of them were male. Thirty-seven of the patients had a radiologically proven pneumonia. Eighteen of 37 (48.6%) patients with pneumonia had an underlying co-morbid medical condition, and 14 required intensive care unit admission. Patients with pneumonia had higher levels of C-reactive protein. All patients but one received oseltamivir treatment. Six patients with pneumonia received only antiviral therapy, while 31 of the patients with pneumonia received concomitant antibiotic therapy. Three patients who required mechanical ventilatory support died due to respiratory insufficinency. Although our study implicates the later periods of the pandemic, there were no significant differences for patients’ characteristics between our study and previous reports from the countries where the pandemic first occurred.

scholarly journals Clinical profile and outcome of patients admitted with swine-origin Influenza A H1N1 virus infection at a tertiary care hospital in Western India

2019 ◽  
Vol 6 (4) ◽  
pp. 1271
Author(s):  
Ambika Sharma ◽  
R. S. Mathur
Keyword(s):  
Virus Infection ◽  
Influenza A ◽  
H1n1 Virus ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Swine Flu ◽  
Severe Illness ◽  
Care Hospital ◽  
Influenza A H1n1 ◽  
H1n1 Virus Infection

Background: Most of the studies on swine flu H1N1 have been done during the pandemic phase. There was a sudden upsurge in virus activity in 2015 at many centers in India. The present study was designed to assess the current status and pattern of H1N1 infection. The primary objective of this study is to study the clinical profile of patients admitted with Swine-origin influenza A (H1N1) virus infection and Secondary objective is to study the clinical outcome in terms of morbidity and mortality.Methods: This was a retrospective observational study done at a tertiary care centre from March 2015 to April 2016. All admitted and confirmed cases of H1N1 swine flu infection were studied for demographic details, co-existing medical conditions and clinical presentation. Data regarding the course of disease, complications, treatments and outcomes were recorded from the clinical record.Results: Common presenting symptoms were cough and fever (95%). Common findings were fever (62.5%), tachycardia, tachypnea and crepitation on auscultation (58.5%). Associated comorbidities were Diabetes mellitus (19.5%), Chronic kidney disease (17%), immunosuppression (9.8%). Consolidation was seen in nearly half of the patients on radiological imaging. Complications noted in our patients were pneumonia (45%), respiratory failure (31%) and ARDS (14.6%). Seventeen percent of patients required non-invasive and invasive mechanical ventilation. Around 25 percent of cases, required ICU admission while two patients died during the hospital stay.Conclusions: The study emphasizes and restates the morbidities caused by H1N1 swine influenza infection as nearly half of the patients in this study experienced severe illness and complications.

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