scholarly journals Medical literature search dot com

2011 ◽  
Vol 77 (2) ◽  
pp. 135 ◽  
Author(s):  
Vivek Jain ◽  
DeepakK Raut
2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Veeraraghavan Meyyur Aravamudan ◽  
Chaozer Er ◽  
Ikram Hussain ◽  
Nicholas wong wai Cheong ◽  
Chong Chern Hao ◽  
...  

Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without the need of etoposide. Based on our literature search, this is the first case of parvovirus related HLH in a patient with HbH disease in the medical literature.


2017 ◽  
Vol 8 (3) ◽  
pp. ar.2017.8.0210 ◽  
Author(s):  
Lauren W. Kaminsky ◽  
Theodore Kelbel ◽  
Fay Ansary ◽  
Timothy Craig

Background Hereditary angioedema (HAE) is a life-long disease that often manifests by puberty. Treatment of attacks is essential to improve quality of life and to decrease morbidity and mortality. During pregnancy, treatment is limited because multiple treatment options, including icatibant, are not approved for use during pregnancy. Objective We report the outcomes of three pregnancies during which icatibant was used by a patient with HAE with normal C1-inhibitor for treatment of attacks. We also reviewed the literature for reports of icatibant use during pregnancy for outcomes and adverse events. Methods We report on a patient who treated herself with icatibant during three separate pregnancies. Postpartum follow-up verified the health of the mother and children. We also performed a complete literature search of medical literature data bases on icatibant use during pregnancy. Results The patient in our report administered multiple doses of icatibant during three pregnancies. The child born from the first pregnancy and the child from the third pregnancy were born at term and without congenital anomalies. The child from the second pregnancy was 1-month preterm. All three children were developmentally normal. The literature search identified two case reports and one abstract of limited icatibant use without adverse events during pregnancy in patients with HAE. These pregnancies resulted in the births of healthy infants. Conclusion From a search of the literature, three cases of icatibant use during pregnancy resulted in healthy infants. In addition, we report that from icatibant use in three separate pregnancies, one infant was born prematurely, but there were no birth defects. From follow-up, the children continued meeting developmental milestones. This report adds to the acquisition of knowledge for drug adverse events during postmarketing surveillance for icatibant use during pregnancy.


2005 ◽  
Vol 19 (4) ◽  
pp. 1-21 ◽  
Author(s):  
Fred G. Barker ◽  
Bob S. Carter

Systematic reviews and metaanalyses have become increasingly popular ways of summarizing, and sometimes extending, existing medical knowledge. In this review the authors summarize current methods of performing meta-analyses, including the following: formulating a research question; performing a structured literature search and a search for trials not published in the formal medical literature; summarizing and, where appropriate, combining results from several trials; and reporting and presenting results. Topics such as cumulative and Bayesian metaanalysis and metaregression are also addressed. References to textbooks, articles, and Internet resources are also provided. The goal is to assist readers who wish to perform their own metaanalysis or to interpret critically a published example.


2009 ◽  
Vol 48 (04) ◽  
pp. 371-380 ◽  
Author(s):  
S. Antani ◽  
Rodney Long ◽  
T. M. Deserno

Summary Objectives: An increasing number of articles are published electronically in the scientific literature, but access is limited to alphanumerical search on title, author, or abstract, and may disregard numerous figures. In this paper, we estimate the benefits of using content-based image retrieval (CBIR) on article figures to augment traditional access to articles. Methods: We selected four high-impact journals from the Journal Citations Report (JCR) 2005. Figures were automatically extracted from the PDF article files, and manually classified on their content and number of sub-figure panels. We make a quantitative estimate by projecting from data from the Cross-Language Evaluation Forum (Image-CLEF) campaigns, and qualitatively validate it through experiments using the Image Retrieval in Medical Applications (IRMA) project. Results: Based on 2077 articles with 11,753 pages, 4493 figures, and 11,238 individual images, the predicted accuracy for article retrieval may reach 97.08%. Conclusions: Therefore, CBIR potentially has a high impact in medical literature search and retrieval.


1972 ◽  
Vol 51 (5) ◽  
pp. 47-50
Author(s):  
William E. Chapman ◽  
Richard L. Rapport ◽  
F. W. Lancaster ◽  
J. Kiffin Penry

2021 ◽  
Vol 33 (S1) ◽  
pp. 82-83
Author(s):  
Marcela Leão Petersen ◽  
Monia Bresolin ◽  
Ariane Madruga Monteiro

It is known that olfactory dysfunction occurs early in neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases and frontotemporal dementia (FTD). Dementia and psychiatric disorders share a number of clinical features, such as psychosis and depression. As such, misdiagnoses across these conditions are not uncommon. A variety of studies show smell dysfunction in schizophrenia, but little is known about other psychiatric disorders. In order to verify the link between olfaction and psychiatric disorders, a medical literature search was carried out in may 2021 using PubMed, and Cochrane Library, including the terms “olfaction” and “olfactory dysfunction” combined individually with “psychiatric disorder” and “depression”. Systematic reviews and meta-analyses written in English from 1991 to 2021 were included. Even thought one review suggested that patients with depression have reduced olfactory performance when compared with healthy, results show studies with different methodology and design which makes it difficult to reach definitive conclusions as how and if olfactory functioning is related to depression. Further studies with the same methodology that examines and separates central and peripheral olfactory processing are needed. Another review showed robust olfactory deficits in schizophrenia and at-risk youths, what indicates that olfactory measures may be a useful marker of schizophrenia risk status. Finally, a systematic review compared olfactory function in FTD, depression, schizophrenia and bipolar disorder. Results revealed that odor identification but not discrimination was severely impaired in FTD, both were impaired in schizophrenia, while no olfactory impairments were observed in depression. Findings in bipolar disorder were mixed. This review showed that testing odor identification and discrimination differentiates FTD from depression and schizophrenia, but not from bipolar disorder. It is possible to conclude that olfactory dysfunction occurs in schizophrenia and dementia but not in depression.


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