A comparative analysis of isolation and antibiotic sensitivity pattern of Pseudomonas aeruginosa isolated from pus and urine with special reference to phenotypic and genotypic expression of extended spectrum beta lactamases (ESBLs)

2013 ◽  
Vol 15 (1) ◽  
pp. 3 ◽  
Author(s):  
PA Shiny ◽  
S Rajendran ◽  
YLakshmi Sarayu
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Comparative Analysis ◽  
Special Reference ◽  
Antibiotic Sensitivity ◽  
Beta Lactamases ◽  
Extended Spectrum ◽  
Sensitivity Pattern ◽  
Extended Spectrum Beta Lactamases

First Detection of OXA-10 Extended-Spectrum Beta-Lactamases and the Occurrence of mexR and nfxB in Clinical Isolates of Pseudomonas aeruginosa from Nigeria

Chemotherapy ◽  
2015 ◽  
Vol 61 (2) ◽  
pp. 87-92 ◽  
Author(s):  
Bamidele T. Odumosu ◽  
Bola A. Adeniyi ◽  
Ram Chandra
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Efflux Pump ◽  
Clinical Isolates ◽  
Beta Lactamases ◽  
First Report ◽  
Extended Spectrum ◽  
Pcr Rflp ◽  
Extended Spectrum Beta Lactamases ◽  
Regulator Genes

Background: The characterization of β-lactamase production in Pseudomonasaeruginosa is rarely reported in Nigeria. The objective of this study was to investigate the occurrence and characterize the different β-lactamases as well as mechanisms of fluoroquinolones resistance among P. aeruginosa isolated from various clinical sources from Nigeria. Materials and Method: Isolates were investigated using PCR, RFLP and sequencing for the detection of various β-lactamases and efflux pump regulator genes. Result: The prevalence of OXA-10, AmpC, CTX-M and SHV in P. aeruginosa was 80, 70, 5 and 5%, respectively. The coexistence of blaOXA-10 with blaAmpC, blaSHV and blaCTX-M was reported in 40, 5 and 5% of isolates, respectively. The efflux pump regulator genes mexR and nfxB were both amplified in 45% of the OXA-10-positive isolates. Conclusion: This is the first report of the characterization of OXA-10 extended-spectrum β-lactamases and occurrence of mexR and nfxB efflux regulator genes in clinical isolates of P. aeruginosa in Nigeria.

Determination of extended spectrum beta-lactamases, metallo-beta-lactamases and AmpC-beta-lactamases among carbapenem resistant Pseudomonas aeruginosa isolated from burn patients

Burns ◽  
2014 ◽  
Vol 40 (8) ◽  
pp. 1556-1561 ◽  
Author(s):  
Davood Kalantar Neyestanaki ◽  
Akbar Mirsalehian ◽  
Fereshteh Rezagholizadeh ◽  
Fereshteh Jabalameli ◽  
Morovat Taherikalani ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Burn Patients ◽  
Beta Lactamases ◽  
Carbapenem Resistant ◽  
Extended Spectrum ◽  
Extended Spectrum Beta Lactamases
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