scholarly journals Myxoid chondrosarcoma of sphenoid bone

2012 ◽  
Vol 03 (03) ◽  
pp. 395-398 ◽  
Author(s):  
Amit K. Chowhan ◽  
Nandyala Rukmangadha ◽  
Rashmi Patnayak ◽  
Mandyam Kumaraswamy Reddy ◽  
Chandra Mouliswara Prasad Bodapati ◽  
...  
Keyword(s):  
Soft Tissues ◽  
Treatment Protocol ◽  
Sphenoid Bone ◽  
Occipital Region ◽  
Radiological Findings ◽  
Diagnostic Dilemma ◽  
Histopathological Features ◽  
Myxoid Chondrosarcoma ◽  
Clinical Presentations ◽  
Prognostic Importance

ABSTRACTThe myxoid variant of chondrosarcoma is usually seen in soft tissues where it is known as chordoid sarcoma or parachordoma. Rarely, it involves bone and when it does, cranial bones are the preferred location. This tumor is frequently amalgamated with the chondroid variant of chordoma, especially when the lesion occurs in the sphenoid bone/spheno-occipital region, because of their similar clinical presentations, anatomical locations, radiological findings, and mistaken histopathological features. It is essential to distinguish myxoid chondrosarcoma from the chondroid variant of chordoma, because of the different treatment protocol and prognostic importance. We present such a location-based diagnostic dilemma, solved successfully with ancillary immunohistochemistry.

Low-Level Laser Therapy as a Coadjuvant in Sodium Hypochlorite Extrusion Management

2020 ◽  
Author(s):  
Diana Ened Rodríguez Zaragoza
Keyword(s):  
Laser Therapy ◽  
Sodium Hypochlorite ◽  
Conventional Treatment ◽  
Soft Tissues ◽  
Treatment Protocol ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Severe Tissue

Aim: The extrusion of sodium hypochlorite through the apical foramen is an accident that can occur during the endodontic treatment although is relatively uncommon, Due to the severe tissue damage that is caused by the solution, the management becomes important to prevent serious sequalae. Low-level laser therapy might be useful to treat damaged soft tissues because of its bio modulatory effects, which may reduce edema and prevent infection. Methods: In this clinical case, the accidental leakage of 5% sodium hypochlorite during the preparation of the root canal of an upper left canine is reported. The accident caused immediate and intense pain and severe edema and ecchymosis. The conventional treatment protocol was applied along with low-level laser therapy. Results: Clinical examination revealed the healing of soft tissue in thirteen days, besides a significant pain reduction in three days after laser therapy was applied. Conclusion: The combination of low-level laser therapy with a conventional treatment protocol could be a useful tool to manage such an accident.

scholarly journals Osteoid Osteoma of the Atlas in a Boy: Clinical and Imaging Features–A Case Report and Review of the Literature

2020 ◽  
Author(s):  
Adelaide Valluzzi ◽  
Salvatore Donatiello ◽  
Graziana Gallo ◽  
Monica Cellini ◽  
Antonino Maiorana ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Osteoid Osteoma ◽  
Soft Tissues ◽  
Tissue Reaction ◽  
Imaging Features ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Radiological Findings ◽  
First Case ◽  
Upper Cervical

AbstractOsteoid osteoma is a benign osteoblastic tumor, quite uncommon in the spine. We report a case of an osteoid osteoma involving the atlas in a 6-year-old boy, who presented with suboccipital pain and torticollis. Initial radiological findings were ambiguous as magnetic resonance imaging showed mainly edema of upper cervical soft tissues. The subsequent computed tomography depicted a lesion of left lamina of C1. As conservative treatment failed, the lesion was surgically resected and the patient became pain free. To our knowledge, this is the first case of osteoid osteoma involving the atlas associated with abnormal soft tissue reaction reported in literature.

Pulmonary Preneoplasia

2008 ◽  
Vol 132 (7) ◽  
pp. 1073-1078 ◽  
Author(s):  
Sanja Dacic
Keyword(s):  
Diagnostic Procedures ◽  
World Health ◽  
Preneoplastic Lesions ◽  
Cell Hyperplasia ◽  
Diagnostic Dilemma ◽  
Gene Markers ◽  
Lung Carcinomas ◽  
Molecular Abnormalities ◽  
Prognostic Importance ◽  
Health Organization

Abstract Context.—Improved screening techniques for lung cancer have resulted in detection of lesions that are considered to represent precursors of invasive lung carcinomas. These lesions may cause a diagnostic dilemma particularly on small biopsy or cytology specimens. Ancillary studies are usually not helpful, and diagnosis is based on morphology alone. Recognition of these lesions is very important to prevent potential diagnostic mistakes that may result in inadequate patient management. Future molecular studies may provide clinically useful diagnostic and prognostic gene markers. Objective.—To review currently proposed morphologic criteria for precursor lesions of non–small cell lung carcinomas including squamous dysplasias, atypical adenomatous hyperplasia, and diffuse idiopathic neuroendocrine cell hyperplasia. Major molecular abnormalities are briefly discussed. Data Sources.—Published literature and recent World Health Organization classification of lung tumors. Conclusions.—Practicing surgical pathologists must be familiar with morphology of recognized pulmonary preneoplastic lesions that are more frequently detected radiographically and subjected to diagnostic procedures. Future understanding of underlying molecular abnormalities associated with progression of these lesions into invasive lung carcinoma may result in a development of molecular assays with potential diagnostic and prognostic importance.

scholarly journals Retracted: Diagnostic Dilemma of a Diaphragmatic Hernia

2018 ◽  
Vol 4 (3) ◽  
Author(s):  
Salman Yahya ◽  
Sonia Zafar ◽  
Hafsa S. Babar
Keyword(s):  
Diaphragmatic Hernia ◽  
Turning Point ◽  
Rare Complication ◽  
Young Male ◽  
Acute Ischemia ◽  
Radiological Findings ◽  
Diagnostic Dilemma ◽  
High Index Of Suspicion ◽  
Disease Free

Diaphragmatic hernia post esophagectomy is a rare complication but a reality in its existence. It is typically difficult to diagnose but highly depends on keeping high index of suspicion. In our case report, the young male who underwent esophagectomy for esophageal carcinoma, remained disease free and stable in his 9 months follow up, suddenly presented in the emergency department with the symptoms of shortness of breath, chest pain, vomiting and tachycardia. The case was typically complicated by the initial treatment given for acute ischemia and cardiogenic shock. Radiological findings proved to be helpful and turning point in the diagnosis and overall management.

Epithelial-Type and Neural-Type Cadherin Expression in Malignant Noncarcinomatous Neoplasms With Epithelioid Features That Involve the Soft Tissues

2002 ◽  
Vol 126 (4) ◽  
pp. 425-431 ◽  
Author(s):  
William B. Laskin ◽  
Markku Miettinen
Keyword(s):  
Malignant Melanoma ◽  
Synovial Sarcoma ◽  
Soft Tissues ◽  
Clear Cell ◽  
Epithelioid Sarcoma ◽  
Clear Cell Sarcoma ◽  
Extraskeletal Myxoid Chondrosarcoma ◽  
Cell Sarcoma ◽  
Myxoid Chondrosarcoma ◽  
Poorly Differentiated

Abstract Context.—Transmembrane adhesion molecules, epithelial-type cadherin (ECAD) and neural-type cadherin (NCAD), help in regulating transformations between epithelial and mesenchymal cells in the developing embryo and in maintaining the epithelioid phenotype. Consequently, the presence of epithelioid cells in certain malignant noncarcinomatous neoplasms raises speculation that the expression of ECAD and NCAD in these neoplasms may have diagnostic significance. Objective.—To investigate the utility of ECAD and NCAD immunoexpression in distinguishing malignant (noncarcinomatous) neoplasms with epithelioid features that involve the soft tissues. Design.—Membranous immunoreactivity of anti-ECAD and anti-NCAD was evaluated on archived cases selected from the files of the Armed Forces Institute of Pathology. Results.—Epithelial-type cadherin was found in biphasic synovial sarcoma (35 of 35 cases), malignant melanoma (13/21), monophasic fibrous synovial sarcoma (13/26), clear cell sarcoma (4/9), poorly differentiated synovial sarcoma (3/13), diffuse mesothelioma (4/20), malignant epithelioid peripheral nerve sheath tumor (1/6), and epithelioid sarcoma (5/62). Neural-type cadherin was observed in chordoma (11/11), biphasic synovial sarcoma (30/35), diffuse mesothelioma (14/20), malignant melanoma (14/25), epithelioid sarcoma (24/63), epithelioid angiosarcoma (1/4), poorly differentiated synovial sarcoma (2/13), clear cell sarcoma (1/10), and monophasic fibrous synovial sarcoma (1/26). Eighteen cases of primary cutaneous squamous cell carcinomas all tested positive for ECAD, whereas NCAD was focally observed in 5 cases. No expression of either molecule was observed in cases of epithelioid hemangioendothelioma (n = 9), alveolar soft part sarcoma (n = 8), and extraskeletal myxoid chondrosarcoma (n = 7). Conclusions.—Epithelial-type and neural-type cadherins are found in a variety of noncarcinomatous neoplasms with epithelioid features that involve the soft tissues and can be utilized, in association with other immunomarkers, in distinguishing chordoma (100% NCAD) from extraskeletal myxoid chondrosarcoma and conventional chondrosarcoma of bone (0% NCAD), squamous cell carcinoma (100% ECAD) from epithelioid sarcoma (8% ECAD), and biphasic synovial sarcoma (100% ECAD) from diffuse mesothelioma (20% ECAD).

Immigration Brings New Pathology with No Standardized Treatment Protocol

2018 ◽  
Vol 108 (6) ◽  
pp. 517-522
Author(s):  
Tara L. Harrington ◽  
Denten Eldredge ◽  
Erica K. Benson
Keyword(s):  
Opportunistic Infections ◽  
Treatment Options ◽  
Treatment Protocol ◽  
Current Treatment ◽  
Foot And Ankle ◽  
Treatment Protocols ◽  
Clinical Presentations ◽  
Standardized Treatment ◽  
Madura Foot ◽  
Antimicrobial Interventions

Madura foot is an uncommon invasive soft-tissue infection that foot and ankle specialists encounter. We present two rare cases of Phialemonium and Phaeoacremonium fungi infections of the foot diagnosed in northern California to inform physicians on the presentation and current treatment options for this unique pathology. The two cases presented outline the clinical presentations, diagnostic data, and surgical and antimicrobial interventions. There is a concentration on the antimicrobial options depending on which of the over 20 species is encountered. The pertinent literature and supporting data are reviewed to create an outline for discussion of treatment protocols when faced with these emerging opportunistic infections.

Primary synovial sarcoma of the lung: a rare presentation, diagnostic dilemma and review of literature

2020 ◽  
Vol 13 (11) ◽  
pp. e237678
Author(s):  
Laxman Pandey ◽  
Deepa Joseph ◽  
Rajesh Pasricha ◽  
Manoj Kumar Gupta
Keyword(s):  
Synovial Sarcoma ◽  
Left Lung ◽  
Treatment Protocol ◽  
Rare Presentation ◽  
Diagnostic Dilemma ◽  
Rare Tumour ◽  
Improved Outcomes ◽  
Long Term Follow Up ◽  
Lung Metastasectomy ◽  
Malignant Lung Tumours

Primary synovial sarcoma of the lung (PSSL) is a rare tumour with only 0.5% incidence among other primary malignant lung tumours. Published medical literature regarding the natural history treatment protocol and clinical outcomes of PSSL remains limited. Here, we present a case of a 39-year-old man with primary synovial sarcoma with long-term follow-up, which was initially viewed as a metastasis from another unknown site. After evaluating histopathologically from the specimen post left lung metastasectomy and ruling out any other site for neoplastic changes, the diagnosis of PSSL was confirmed. Furthermore, this article reviews the literature and discusses various aspects of PSSL, including clinical presentation, radiological imaging and pathological characteristics, diagnostic dilemma, management and prognosis. This paper serves to provide an update and aims to enhance the understanding of PSSL. Timely diagnosis and treatment are imperative to achieve improved outcomes.

Thyroid metastasis to the oral soft tissues: Case report of a diagnostic dilemma

1993 ◽  
Vol 51 (5) ◽  
pp. 588-593 ◽  
Author(s):  
Bryan Whitaker ◽  
Kermie Robinson ◽  
Karlene Hewan-Lowe ◽  
Steven Budnick
Keyword(s):  
Case Report ◽  
Soft Tissues ◽  
Thyroid Metastasis ◽  
Diagnostic Dilemma

Spondylodiscitis presenting as pleural effusion in a geriatric female: a case report

2020 ◽  
pp. 1-11
Author(s):  
Funda Secik Arkin ◽  
Gulfidan Aras
Keyword(s):  
Case Report ◽  
Chest Pain ◽  
Pleural Effusion ◽  
Clinical Laboratory ◽  
Medical Problem ◽  
Pulmonary Diseases ◽  
Radiological Findings ◽  
Clinical Presentations ◽  
Low Incidence ◽  
Exudative Pleural Effusion

Abstract Pleural effusion is a frequently seen medical problem caused by pulmonary and non-pulmonary diseases. Spondylodiscitis is a very rare cause of pleural effusion and is typically diagnosed based on clinical, laboratory, microbiological and radiological findings. The low incidence and different clinical presentations of Spondylodiscitis make its diagnosis and treatment challenging. We present the case of a 78-year-old female who was initially admitted due to chest pain and, upon chest radiography, was found to have pleural effusion; and eventually diagnosed with spondylodiscitis. Keywords: Spondylodiscitis, exudative pleural effusion, geriatrics, vertebra, infection. Continuous...

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