Pattern of visceral metastasis from breast cancer patients in Ahmadu Bello University Teaching Hospital, Zaria, North Western Nigeria

2019 ◽  
Vol 4 (2) ◽  
pp. 31
Author(s):  
PeterPase Abur ◽  
LazarusM Yusufu ◽  
VincentI Odigie
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Teaching Hospital ◽  
University Teaching ◽  
Breast Cancer Patients ◽  
Visceral Metastasis ◽  
North Western

scholarly journals Level of Adherence to Cytotoxic Drugs by Breast Cancer Patients’ in Lagos State University Teaching Hospital

2015 ◽  
Vol 06 (04) ◽  
pp. 383-389 ◽  
Author(s):  
Popoola Abiodun ◽  
Samira Makanjuola ◽  
Sowunmi Anthonia ◽  
Igwilo Adaeze ◽  
Mobolaji Oludara ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Teaching Hospital ◽  
Cytotoxic Drugs ◽  
University Teaching ◽  
State University ◽  
Breast Cancer Patients ◽  
Lagos State

Evaluation of the Proliferation of Breast Cancer Cells Among Women in Osun State, Southwest Nigeria

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S139-S139
Author(s):  
Sina Iyiola ◽  
Enweani Ifeoma ◽  
Anthony Ngokere ◽  
Godwin Avwioro ◽  
Akinwumi Komolafe
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Teaching Hospital ◽  
Time Lag ◽  
Mean Value ◽  
University Teaching ◽  
High Morbidity ◽  
Breast Cancer Patients ◽  
High Morbidity Rate ◽  
The Mean

Abstract Objectives Nigeria has one of the highest morbidity rates from breast cancer; therefore, this work examined the proliferation rate of breast cancer and the hospital presentation time lag among women in Osun State, Nigeria. Methods This cross-sectional study was carried out in Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife and Ladoke Akintola University Teaching Hospital, Oshogbo, Nigeria. The request cards and tissue blocks were sorted from the year 2014 to 2017. The time lag it took the patients to report at the hospitals was retrieved from the request cards. The breast tissue blocks were sectioned, stained with H&E, and graded. A representative tissue block was selected for each patient. Sections obtained from the blocks were stained with Mki67 antibody using a diaminobenzidine horseradish peroxidase technique. The cells were semiquantitatively scored as percentage of tumor cells stained brown. The mean ± SD was calculated. Results Out of 240 breast cancer patients sampled, 6 (2.5%), 97 (40.4), and 137 (57.1%), respectively, were grades 1, 2, and 3. The mean value of MKi67 was 23.90 ± 20.38, median 16.00. The mean value for grade 2 cancer was 15.31 ± 14.34; grade 3 cancer was 37.95 ± 22.47. Only 21.9% of breast cancer patients came to clinic within 3 months of lumps awareness in their breasts while 64.5% attended clinic after 6 months. Conclusions Breast cancer among the Osun State women was not very aggressive when comparing the Mki67 values obtained in this study with the values obtained in the developed world. Greater percentages of women with breast cancer waited too long before presenting themselves at the hospital. Thus, a high morbidity rate was recorded.

scholarly journals Serum Alkaline Phosphatase as a Predictive Marker for Bone Metastasis in Breast Cancer Patients Seen in a Tertiary Health Institution in Northern Nigeria

2020 ◽  
Vol 1 (2) ◽  
Author(s):  
Usman Malami Aliyu ◽  
Musa Ali-Gombe
Keyword(s):  
Breast Cancer ◽  
Alkaline Phosphatase ◽  
Bone Metastases ◽  
Cancer Patients ◽  
Teaching Hospital ◽  
Serum Alkaline Phosphatase ◽  
Metastatic Breast ◽  
Predictive Marker ◽  
University Teaching ◽  
Breast Cancer Patients

Introduction: Early detection of bone metastases is helpful in the treatment of breast cancer. Change in serum levels of alkaline phosphatase could assist diagnosis and follow-up of metastatic breast cancer. Aim: This study aimed to determine the clinical correlates of serum alkaline phosphatase (ALP) levels in breast cancer patients with bone metastases seen in the Department of Radiotherapy and Oncology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria. Material and Methods: All breast cancer patients’ case note seen at the department of Radiotherapy and Oncology Usmanu Danfodiyo University Teaching Hospital, Sokoto from January 2012 to January 2017 were retrieved. The Information extracted include age, pre-treatment serum ALP, presence or absence of met

scholarly journals 1K4Cancer Breaks the Silence: A Crowd-Funding Campaign by Sebeccly Cancer Care

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 184s-184s
Author(s):  
A. Udoh ◽  
O. Salako ◽  
V. Okafor
Keyword(s):  
Breast Cancer ◽  
Social Media ◽  
Cancer Patients ◽  
Teaching Hospital ◽  
Cancer Care ◽  
Financial Burden ◽  
Relationship Management ◽  
University Teaching ◽  
Cancer Drug ◽  
Breast Cancer Patients

Amount raised: The 1K4Cancer campaign raised a total of $18,099. Background and context: Poverty, chronicity of spending, paying out-of-pocket for health care needs, and the prohibitive cost of cancer drugs are some of the reasons cancer patients don't start or complete treatment. Over 90% of Nigerian cancer patients pay for healthcare expenses out-of-pocket; putting a heavy strain on their finances and those of their caregivers. Sebeccly is a cancer charity that enables cancer care access to indigent cancer patients through several fundraising modalities, one of which is the 1K4Cancer. The campaign is a cancer drug fund and crowd fundraiser that appeals for a minimum donation worth $2.50. Launched in October 2012 (for 3 months), and relaunched in March 2018, 1K4Cancer provides treatment aid to breast cancer patients. Aim: To raise funds and provide access to cancer care to indigent breast cancer patients. Strategy/Tactics: The 1K4Cancer campaign reaches out to individuals/organizations by leveraging on social media, relationship management with donors and several 1K4Cancer ambassadors to engage networks to raise funds to support cancer treatment and screening services. This strategy has an online and offline component, with the offline driving the online component. Program process: The 1K4Cancer runs under 7 broad categories: Community events: Focus on advocacy and education on cancer prevention and early detection. Health talks and the 1K4Cancer appeal are delivered during community outreaches. Online community engagements: partnerships with online blogs and influencers to promote the campaign were secured. The social media community was engaged in heartwarming messages and call-to-action statements to support indigent cancer patients. Media partnership: partnerships with online and traditional media houses were secured. The 1K4Cancer message was published on several eminent blogs. Relationship management with donors: past and prospective donors were engaged to promote the campaign. 1K4Cancer remains transparent and accountable through an online monthly newsletter. Donation collection: donations were made through online bank transfer and Sebeccly's online donation platforms. Volunteers: recruitment of 1K4Cancer volunteers who helped to promote and create more awareness about the campaign offline. Partnerships with hospitals: the beneficiaries of the campaign receive cancer care at Lagos University Teaching Hospital, and Lagos State University Teaching Hospital. Costs and returns: $2715 has been spent on online adverts, branding materials, creatives, publications, administrative charges, and logistics. Total returns so far: $15,384. What was learned: Leveraging on goodwill, accountability, the Internet, and a compelling story are necessary ingredients to a crowd-funding campaign. The 1K4Cancer is an innovative crowd-funding campaign that relieves the financial burden of cancer patients and help achieve access to quality cancer care.

scholarly journals Data on the survival times of breast cancer patients in a Teaching Hospital, Osogbo

Data in Brief ◽  
2020 ◽  
Vol 32 ◽  
pp. 106109
Author(s):  
Phillip Oluwatobi Awodutire ◽  
Oladapo Adedayo Kolawole ◽  
Oluwatosin Ruth Ilori
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Teaching Hospital ◽  
Breast Cancer Patients ◽  
Survival Times

scholarly journals Knowledge and Health Seeking Behaviour of Breast Cancer Patients in Ghana

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Francis Agbokey ◽  
Elorm Kudzawu ◽  
Mawuli Dzodzomenyo ◽  
Kenneth Ayuurebobi Ae-Ngibise ◽  
Seth Owusu-Agyei ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Patients ◽  
Teaching Hospital ◽  
Cultural Influences ◽  
Signs And Symptoms ◽  
Health Providers ◽  
Breast Cancer Patients ◽  
Health Seeking Behaviour ◽  
Health Seeking

Background. Breast cancer is a major contributor to cancer-related deaths among women worldwide, despite the numerous measures employed to prevent and manage the disease. This study explored the knowledge and health seeking behaviour of breast cancer patients at the Komfo Anokye Teaching Hospital. Methods. A descriptive cross-sectional study was conducted at Komfo Anokye Teaching Hospital in Kumasi, Ghana, from June 2014 to July 2014. Thirty-five participants were purposively selected. The responses to questions about their experiences with breast cancer were determined using indepth interviews. Transcripts were coded and analysed using NVIVO version 10.0. Results. Participants’ knowledge about signs and symptoms of breast cancer after their diagnosis was high but low for risk factors. Screening for breast cancer through self-breast examination was infrequently performed prior to their diagnosis. The patients’ first point of care was generally health facilities. Some patients reported late due to misinterpretation of signs and symptoms, cultural influences and fear of losing their breast to surgery, physician delay, health providers’ laxity, and disinterest in breast cancer. Men, for example, husbands, decide on where and when breast cancer patients go for treatment. Conclusion. There is poor knowledge of the risk factors for developing breast cancer. Patients resorted to the hospital as first options for cure but were generally delayed in doing so. There is the need to create awareness about breast cancer among the general population.

Efficacy and safety of metronomic capecitabine and gefitinib in heavily pretreated metastatic triple-negative breast cancer.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 1071-1071
Author(s):  
Anantbhushan Ranade ◽  
Kanaka Govind Babu ◽  
Purvish M. Parikh ◽  
Jk Singh ◽  
Manisha Singh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Cancer Patients ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Metastatic Breast ◽  
Breast Cancer Patients ◽  
Visceral Metastasis ◽  
Egfr Expression ◽  
Heavily Pretreated

1071 Background: Metronomic chemotherapy regimens have shown efficacy in patients with metastatic breast cancer by antiangiogenic mechanisms. When used metronomically the toxicity profile of capecitabine is low. Triple negative breast cancer is a common problem in India and developing countries. Approximately 30% of triple negative breast cancer express EGFR and its mutation. Methods: Since October 2003 to December 2011 we objectively tested response rates, clinical benefit, and safety of gefitinib and capecitabine administered with a metronomic schedule of 500 mg thrice daily in heavily pretreated metastatic breast cancer patients with gefitinib 250 mg once daily. 300 patients were screened for EGFR expression. Among 85 enrolled patients with EGFR positivity, 76 were evaluable. ECOG performance status (PS) was 0-2, median age 52 years (range 36-65), bone plus visceral metastasis in 40% of patients. Rest had only visceral metastasis. All the patients were pretreated with anthracyclines and taxanes. The combination was administered for a median duration of 32 weeks (range 12-166). Results: We observed 18 partial responses (PR: 24%), 42 (55%) stable disease (SD). Median time to progression was 53 weeks, (95% CI, range 12-166 weeks). Safety of metronomic capecitabine with gefitinib was excellent. Neither grade 2-4 haematological or clinical side effects were recorded. Only 12 patients experienced grade I (WHO) hand-foot syndrome. Conclusions: Treatment with metronomic capecitabine and gefitinib was effective and minimally toxic in heavily pretreated breast cancer patients.

Sign in / Sign up

Export Citation Format

Share Document