scholarly journals Use of World Health Organization susceptibility test for malaria vector control in South-Eastern Nigeria: A discourse

2019 ◽  
Vol 4 (2) ◽  
pp. 29
Author(s):  
IbangaEyo Ekong ◽  
JoelD Akilah
Keyword(s):  
Vector Control ◽  
World Health Organization ◽  
Malaria Vector ◽  
Susceptibility Test ◽  
World Health ◽  
Malaria Vector Control ◽  
South Eastern ◽  
Health Organization

scholarly journals EFEKTIFITAS PENGGUNAAN KELAMBU BERINSEKTISIDA (LLINs) TERHADAP KASUS MALARIA (Studi Di Desa Ngreco Kecamatan Tegalombo Kabupaten Pacitan Tahun 2016)

2017 ◽  
Vol 15 (1) ◽  
Author(s):  
Rizka Ilmawati ◽  
Sri Mardoyo ◽  
Suroso Bambang Eko Warno
Keyword(s):  
Vector Control ◽  
Malaria Vector ◽  
World Health ◽  
Malaria Vector Control ◽  
Insecticide Treated Nets ◽  
Mosquito Net ◽  
Control Effort ◽  
The World ◽  
Quasi Experimental ◽  
Health Organization

ABSTRACTMalaria is a contagious disease that still becomes wide health problem in the world, including Indonesia.In 2014, API of Pacitan was the highest in East Java with 75 patients suffered from malaria. One of the endemicvillage in Pacitan is Ngreco village. Malaria vector control effort undertaken in the village is the use of insecticidetreatedbed nets, as recommended by the World Health Organization (WHO). The use of insecticide-treated netseffectively prevent transmission of malaria when supported with good care to insecticide-treated nets.This study aims to determine the effectiveness of insecticide-treated nets used by Ngreco Villagecommunity as malaria vector control to the decline in malaria cases. This is a quasi-experimental research. Thedata were collected through interview and sampling. The research sample was 29 homes for interviews and 4insecticide-treated nets used by the community for Bio-assay Test.The results of this study shows a decrease in new case of malaria in 2007-2010 from 23 new cases into2 new cases in 2011 to 2015. The results of efficacy test conducted on four samples of net used by thecommunity showed that net with 30 months of use (effectiveness <80%) are no longer effective to be used as avector control of malaria, while net with 12 months of use (effectiveness> 80%) is still effective to be used asmalaria vector control.The society should pay more attention on how to laundry the net that it is durable as malaria vectorcontrol. The health center needs to conduct controlling of mosquito nets routinely to find out whether the netsare still effective that replacement or dyeing of the of net can be performed.Keywords: Insecticidal mosquito net, effectiveness, malaria

scholarly journals INSECTICIDE-TREATED BED NETS IN RONDÔNIA, BRAZIL: EVALUATION OF THEIR IMPACT ON MALARIA CONTROL

2014 ◽  
Vol 56 (6) ◽  
pp. 493-497 ◽  
Author(s):  
Gabriel de Deus Vieira ◽  
Sergio de Almeida Basano ◽  
Tony Hiroshi Katsuragawa ◽  
Luís Marcelo Aranha Camargo
Keyword(s):  
Vector Control ◽  
Malaria Vector ◽  
Malaria Incidence ◽  
Secondary Data ◽  
Epidemiological Studies ◽  
World Health ◽  
Bed Nets ◽  
Malaria Vector Control ◽  
Health Organization ◽  
The Impact

Mosquito nets treated with long-lasting insecticide (LLINs), when used in compliance with guidelines of the World Health Organization, may be effective for malaria vector control. In 2012, approximately 150,000 LLINs were installed in nine municipalities in the state of Rondônia. However, no studies have assessed their impact on the reduction of malaria incidence. This study analyzed secondary data of malaria incidence, in order to assess the impact of LLINs on the annual parasite incidence (API). The results showed no statistically significant differences in API one year after LLIN installation when compared to municipalities without LLINs. The adoption of measures for malaria vector control should be associated with epidemiological studies and evaluations of their use and efficiency, with the aim of offering convincing advantages that justify their implementation and limit malaria infection in the Amazon Region.

scholarly journals Quantifying and characterizing hourly human exposure to malaria vectors bites in rural southwest Burkina Faso

2019 ◽  
Author(s):  
D.D Soma ◽  
B Zogo ◽  
P Taconet ◽  
A Somé ◽  
S Coulibaly ◽  
...  
Keyword(s):  
Burkina Faso ◽  
Vector Control ◽  
Rural Area ◽  
Malaria Vector ◽  
Human Exposure ◽  
Protective Efficacy ◽  
Indoor Residual Spraying ◽  
World Health ◽  
Malaria Vectors ◽  
Malaria Vector Control

AbstractBackgroundTo sustain the efficacy of malaria vector control, the World Health Organization (WHO) recommends the combination of effective tools. Before designing and implementing additional strategies in any setting, it is critical to monitor or predict when and where transmission occurs. However, to date, very few studies have quantified the behavioural interactions between humans and Anopheles vectors. Here, we characterized residual transmission in a rural area of Burkina Faso where long lasting insecticidal nets (LLIN) are widely used.MethodsWe analysed data on both human and malaria vectors behaviours from 27 villages to measure hourly human exposure to vector bites in dry and rainy seasons using mathematical models. We estimated the protective efficacy of LLINs and characterised where (indoors vs. outdoors) and when both LLIN users and non-users were exposed to vector bites.ResultsThe percentage of the population who declared sleeping under a LLIN the previous night was very high regardless of the season, with an average LLIN use ranging from 92.43% to 99.89%. The use of LLIN provided > 80% protection against exposure to vector bites. The proportion of exposure for LLIN users was 29-57% after 05:00 and 0.05-12 % before 20:00. More than 80% of exposure occurred indoors for LLIN users and the estimate reached 90% for children under five years old in the dry cold season.ConclusionsThis study supports the current use of LLIN as a primary malaria vector control tool. It also emphasises the need to complement LLIN with indoor-implemented measures such as indoor residual spraying (IRS) and/or house improvement to effectively combat malaria in the rural area of Diébougou. Furthermore, malaria elimination programmes would also require strategies that target outdoor biting vectors to be successful in the area.

scholarly journals 20-Hydroxyecdysone (20E) signaling as a promising target for the chemical control of malaria vectors

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Elodie Ekoka ◽  
Surina Maharaj ◽  
Luisa Nardini ◽  
Yael Dahan-Moss ◽  
Lizette L. Koekemoer
Keyword(s):  
Vector Control ◽  
Signaling Pathway ◽  
Malaria Vector ◽  
Vector Competence ◽  
Rapid Development ◽  
World Health ◽  
Malaria Vectors ◽  
Malaria Vector Control ◽  
Insect Growth Regulators ◽  
Vector Abundance

AbstractWith the rapid development and spread of resistance to insecticides among anopheline malaria vectors, the efficacy of current World Health Organization (WHO)-approved insecticides targeting these vectors is under threat. This has led to the development of novel interventions, including improved and enhanced insecticide formulations with new targets or synergists or with added sterilants and/or antimalarials, among others. To date, several studies in mosquitoes have revealed that the 20-hydroxyecdysone (20E) signaling pathway regulates both vector abundance and competence, two parameters that influence malaria transmission. Therefore, insecticides which target 20E signaling (e.g. methoxyfenozide and halofenozide) may be an asset for malaria vector control. While such insecticides are already commercially available for lepidopteran and coleopteran pests, they still need to be approved by the WHO for malaria vector control programs. Until recently, chemicals targeting 20E signaling were considered to be insect growth regulators, and their effect was mostly studied against immature mosquito stages. However, in the last few years, promising results have been obtained by applying methoxyfenozide or halofenozide (two compounds that boost 20E signaling) to Anopheles populations at different phases of their life-cycle. In addition, preliminary studies suggest that methoxyfenozide resistance is unstable, causing the insects substantial fitness costs, thereby potentially circumventing one of the biggest challenges faced by current vector control efforts. In this review, we first describe the 20E signaling pathway in mosquitoes and then summarize the mechanisms whereby 20E signaling regulates the physiological processes associated with vector competence and vector abundance. Finally, we discuss the potential of using chemicals targeting 20E signaling to control malaria vectors.

Susceptibility of Anopheles gambiae complex to carbamates and organophosphate insecticides in Uyo, Akwa Ibom State, Nigeria

2020 ◽  
Vol 41 (1) ◽  
pp. 114-118
Author(s):  
N.I. Udoidung ◽  
K.N. Opara ◽  
P.D. Okodi ◽  
N.D. Ekpo ◽  
I. Atting
Keyword(s):  
Vector Control ◽  
Anopheles Gambiae ◽  
Malaria Vector ◽  
Control Strategies ◽  
Sub Saharan Africa ◽  
World Health ◽  
Malaria Vector Control ◽  
Insecticide Susceptibility ◽  
Post Exposure ◽  
Organophosphate Insecticides

Rapid emergence in insecticide resistance among malaria vector populations to commonly used public health insecticides poses a challenge to current malaria vector control strategies and interventions in sub- Saharan Africa. This study was conducted to determine the susceptibility status of female An.gambiae s.l to Propoxur (0.01%) and bendiocarb (0.1%) (carbamate) and pirimiphosmethyl (0.25%) (organophosphate) insecticides in Uyo Metropolis, Akwa Ibom State, Nigeria. The larvae of An. gambiae s.l were collected from natural water bodies and other potential breeding sites from different sites in Uyo Metropolis. Insecticide susceptibility bioassays were performed according to the World Health Organization standard operating procedures on 2-3 days old, sugar-fed but none blood fed female Anopheles mosquitoes. Post exposure mortality after 24 hours and knockdown values for KDT50 and KDT95 were calculated. Knock-down at 1 hour insecticide exposure ranged from 94 % to 100 %. Mortality after 24 hours post exposure was 100% for all insecticides except Propoxur which was 98 %. There was high variability in KDT50 and KDT95 values (in minutes) with propoxur (4.337 and 15.620), Bendiocarb (9.523 and 20.996) and pirimiphosmethyl (39.908 and 61.722) respectively. Adopting the WHO criteria, the mosquitoes were not resistant to any of the insecticides tested. The results therefore showed that vector control campaigns employing the use of any of these insecticides in the study area would not be compromised. However, there is need for continued monitoring to ensure early detection of resistance. Keywords: Anopheles gambiae; insecticide susceptibility; Uyo; Akwa Ibom State; Nigeria.

scholarly journals The World Health Organization 2030 goals for onchocerciasis: Insights and perspectives from mathematical modelling

2019 ◽  
Vol 3 ◽  
pp. 1545 ◽  
Author(s):  
Keyword(s):  
Vector Control ◽  
World Health Organization ◽  
Neglected Tropical Diseases ◽  
World Health ◽  
African Countries ◽  
High Coverage ◽  
Consultation Process ◽  
The World ◽  
Endemic Areas ◽  
Health Organization

The World Health Organization (WHO) has embarked on a consultation process to refine the 2030 goals for priority neglected tropical diseases (NTDs), onchocerciasis among them. Current goals include elimination of transmission (EOT) by 2020 in Latin America, Yemen and selected African countries. The new goals propose that, by 2030, EOT be verified in 10 countries; mass drug administration (MDA) with ivermectin be stopped in at least one focus in 34 countries; and that the proportion of the population no longer in need of MDA be equal or greater than 25%, 50%, 75% and 100% in at least 16, 14, 12, and 10 countries, respectively. The NTD Modelling Consortium onchocerciasis teams have used EPIONCHO and ONCHOSIM to provide modelling insights into these goals. EOT appears feasible in low-moderate endemic areas with long-term MDA at high coverage (≥75%), but uncertain in areas of higher endemicity, poor coverage and adherence, and where MDA has not yet, or only recently, started. Countries will have different proportions of their endemic areas classified according to these categories, and this distribution of pre-intervention prevalence and MDA duration and programmatic success will determine the feasibility of achieving the proposed MDA cessation goals. Highly endemic areas would benefit from switching to biannual or quarterly MDA and implementing vector control where possible (determining optimal frequency and duration of anti-vectorial interventions requires more research). Areas without loiasis that have not yet initiated MDA should implement biannual (preferably with moxidectin) or quarterly MDA from the start. Areas with loiasis not previously treated would benefit from implementing test-and(not)-treat-based interventions, vector control, and anti-Wolbachia therapies, but their success will depend on the levels of screening and coverage achieved and sustained. The diagnostic performance of IgG4 Ov16 serology for assessing EOT is currently uncertain. Verification of EOT requires novel diagnostics at the individual- and population-levels.

Sensitivity of Culicoides obsoletus (Meigen) (Diptera: Ceratopogonidae) to deltamethrin determined by an adapted WHO standard susceptibility test

Parasitology ◽  
2013 ◽  
Vol 141 (4) ◽  
pp. 542-546 ◽  
Author(s):  
R. DEL RÍO ◽  
R. VENAIL ◽  
C. CALVETE ◽  
C. BARCELÓ ◽  
T. BALDET ◽  
...  
Keyword(s):  
Insecticide Resistance ◽  
World Health Organization ◽  
Bluetongue Virus ◽  
Susceptibility Test ◽  
World Health ◽  
Biting Midges ◽  
Culicoides Obsoletus ◽  
Culicoides Imicola ◽  
Health Organization ◽  
Who Susceptibility Test

SUMMARYBluetongue is a disease of major economic concern in Europe. Its causative agent, bluetongue virus (BTV), is transmitted by several Culicoides species (mainly Culicoides imicola and Culicoides obsoletus in Europe). The application of insecticides on animals may reduce transmission of BTV, however, no formulation is currently licensed specifically against Culicoides midges. The present study assesses the susceptibility of C. obsoletus to deltamethrin using an adapted World Health Organization (WHO) susceptibility test. Midges were exposed to different dosages of deltamethrin for 1 h, and mortality after 1 h and 24 h was recorded. Results indicated that deltamethrin is highly toxic to C. obsoletus since a dose of 1·33×10−4% was enough to kill 50% of the population (LD50) in 24 h. The deltamethrin concentration needed to kill 90% of the population (LD90) was 5·55×10−4%. The results obtained in the present work could help to create a system that can be used to assess insecticide resistance and susceptibility of Culicoides biting midges.

Sign in / Sign up

Export Citation Format

Share Document