Antihyperglycemic and Antioxidant Potential of Plant Extract of Litchi chinensis and Glycine max

2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Sumeet Gupta ◽  
Samrat Chauhan ◽  
Sabina Yasmin ◽  
Monika Saini
Keyword(s):  
Glycine Max ◽  
Plant Extract ◽  
Antioxidant Potential ◽  
Litchi Chinensis

scholarly journals In-vitro antioxidant, antidiabetic and toxic effect of Ageratum houstonianum from Chitwan district Nepal

2020 ◽  
Vol 9 (1) ◽  
pp. 48-54
Author(s):  
Khaga Raj Sharma
Keyword(s):  
Toxic Effect ◽  
Enzyme Inhibition ◽  
Plant Extract ◽  
Methanolic Extract ◽  
Radical Scavenging ◽  
Antioxidant Potential ◽  
Moderate Activity ◽  
Dependent Manner ◽  
Phytotoxic Activity

 Medicinal plants are safe and the oldest natural products used for many years to conserve food, to treat health disorders and to prevent diseases. The active chemical compounds formed during secondary vegetal metabolism is usually responsible for the biological properties of some plant species used throughout the world for various purposes including treatment of diabetes, cancer, infectious diseases etc. The present study was undertaken to analyze the phytochemicals by colour differentiation method, to evaluate the toxic effect by phytotoxic assay, antidiabetic activity by α amylase enzyme inhibition and antioxidant potential by DPPH (2,2-diphenyl-1-picrylhydrazyl) scavenging activity of methanolic extract of Ageratum houstonianum. Treatment of problem in carbohydrate uptake needed the inhibition of α-amylase plays a role in the digestion of polysaccharide and glycogen, is made a strategy for controlling diabetes. For this study whole plant was collected, dried and the powder was made. The extraction was carried out by cold percolation in which methanol was used as a solvent. The methanolic extract was subjected to In-vitro phytotoxic activity by adopting the standard protocol. The α-amylase enzyme inhibition activity of plant extract was carried out by using starch as substrate, pancreatic α amylase as the enzyme, and acarbose as standard. The result of in-vitro phytotoxic bioassay revealed that the plant extract showed moderate activity with percentage growth regulation 80 and 25 percent in a concentration-dependent manner. The α-amylase enzyme inhibition was 74.13 to 99.39 percent in a dose-dependent manner. The antioxidant potential of Ageratum houstonianum extract showed mild activity with IC50 123.67 μg/ml as compared to the standard ascorbic acid IC50 5.38 μg/ ml. It is concluded from the present study that Ageratum houstonianum could be used as a natural source to isolate antioxidant, anti-hyperglycemic agent, herbicide and weedicide as it shows a good α amylase inhibition, radical scavenging and phytotoxic activity respectively.

scholarly journals Some Biological activities of ethanol extract of Marrubium globosum

2021 ◽  
Vol 9 (6) ◽  
pp. 1129-1132
Author(s):  
Mustafa Pehlivan ◽  
Falah Saleh Mohammed ◽  
Ali Erdem Şabik ◽  
Eylem Kına ◽  
Muhittin Dogan ◽  
...  
Keyword(s):  
Plant Extract ◽  
Polar Solvent ◽  
Biological Activities ◽  
Ethanol Extract ◽  
Antibacterial Activities ◽  
Natural Antioxidant ◽  
Antioxidant Potential ◽  
Dilution Method ◽  
Agar Dilution Method ◽  
Agar Dilution

Plants have been used for centuries to treat various diseases. In this study, Marrubium globosum Montbret & Aucher ex Benth. plant was used as a material. The extract of the plant was extracted with the help of soxhlet device using ethanol, which is a good polar solvent, and Rel Assay kits were used to determine the oxidant and antioxidant levels in the plant extract. Antifungal and antibacterial activities of M. globossum were tested against standard bacteria and fungus strains by agar dilution method. As a result of the analysis, TAS value of plant extract was determined as 7.677±0.231, TOS value as 12.387±0.083 and OSI value as 0.162±0.004. In this context, it has been observed that the plant has an important antioxidant potential. In addition, the plant extract was found to be effective against test microorganisms at 50-200 μg/mL extract concentrations. As a result, it has been determined that M. globossum can be a natural antioxidant and antimicrobial source.

scholarly journals ESTIMATION OF PHENOLIC CONTENT, FLAVONOID CONTENT, ANTIOXIDANT, AND ALPHA-AMYLASE INHIBITORY ACTIVITY OF SOME SELECTED PLANTS FROM SIRAHA DISTRICT NEPAL

2020 ◽  
pp. 18-23
Author(s):  
Numer Alam ◽  
Khaga raj Sharma
Keyword(s):  
Plant Extract ◽  
Plant Extracts ◽  
Inhibitory Activity ◽  
Brine Shrimp ◽  
Phenolic Content ◽  
Antioxidant Potential ◽  
Tinospora Cordifolia ◽  
Total Phenolic ◽  
Phytochemical Screening ◽  
Flavonoid Content

Objectives: The purpose of this research was to estimate the phenolic content, flavonoid content, antioxidant, antibacterial, and α-amylase inhibitory activity of some selected plants such as Anethum sowa, Trigonella foenum-graecum, Lepidium sativum, Cuscuta reflexa, Eclipta alba, Leucas cephalotes, and Tinospora cordifolia collected from Siraha district of Nepal using in vitro studies. Methods: Methanol extracts of these medicinal plants were prepared by cold percolation method. Preliminary phytochemical screening was performed by color differentiation method. Total phenolic and flavonoid content were estimated by Folin-Ciocalteu reagent method and aluminum chloride colorimetric method. Antioxidant potential was evaluated by 2,2-diphenyl-1-picrylhydrazyl radical scavenging assay. Furthermore, the α-amylase enzyme inhibitory activity was studied using starch as a substrate, pancreatic α-amylase as the enzyme, and acarbose as standard. Results: Phytochemical screening showed that the plant extracts were found a rich source of secondary metabolites. The phenolic content estimation showed T. foenum-graecum 939.764±0.01, L. sativum 551.63±0.02, A. sowa 306.34±0.06, L. cephalotes 233.19±0.03, T. cordifolia 211.76±0.02, E. alba 202.67±0.02, and C. reflexa Roxb. 145.09±0.09 mg milligram gallic acid equivalent per gram. The flavonoid content estimation showed T. cordifolia 852.07±0.11, L. sativum 553.81±0.05, E. alba 322.13±0.02, A. sowa 329.02±0.05, L. cephalotes 164.93±0.02, and C. reflexa Roxb. 146.37±0.00 mg milligram quercetin equivalent per gram. The antioxidant potential showed by E. alba IC50 33.48±0.82 μg/ml and the values ranged from E. alba 33.48±0.82 to A. sowa 47.62±1.09 μg/ml. The α-amylase inhibitory activity showed by A. sowa 76.78±2.00–E. alba 777.36±9.66 μg/ml. The result of brine shrimp toxicity showed LC50 value >1000 μg/ml. Among the seven plant extracts, only the plant extract of E. alba showed a zone of inhibition 14 mm against Staphylococcus aureus. Conclusions: The plant extract of T. foenum-graecum showed the highest phenolic content, and T. cordifolia showed the highest flavonoid content. The highest antioxidant potential exhibited by E. alba and the highest α-amylase inhibition activity showed by A. sowa. The plant extract of E. alba showed moderate antibacterial activity against S. aureus. All plant extracts were found non-toxic against brine shrimp larvae although further study is needed to assess its mechanism of action.

scholarly journals Antioxidant potential ethanolic extract of Glycine max (l.) Merr. Var. Detam and daidzein

2019 ◽  
Vol 1374 ◽  
pp. 012020
Author(s):  
S Prahastuti ◽  
M Hidayat ◽  
S T Hasianna ◽  
W Widowati ◽  
A Amalia ◽  
...  
Keyword(s):  
Glycine Max ◽  
Ethanolic Extract ◽  
Antioxidant Potential ◽  
Glycine Max L

Sub-acute oral toxicity study of soybean [Glycine max (L.) Merr.] whole plant extract in rats

2016 ◽  
Vol 258 ◽  
pp. S198
Author(s):  
J. Heo ◽  
K. Hwang ◽  
Y. Moon ◽  
J. Kim ◽  
J. Lee ◽  
...  
Keyword(s):  
Glycine Max ◽  
Plant Extract ◽  
Toxicity Study ◽  
Acute Oral Toxicity ◽  
Oral Toxicity ◽  
Whole Plant ◽  
Glycine Max L

scholarly journals Antidiabetic and antioxidant potential of Zanthoxylum armatum DC. leaves (Rutaceae): An endangered medicinal plant

2020 ◽  
Vol 7 (1) ◽  
pp. 93-100
Author(s):  
Sana Khan ◽  
. Richa ◽  
Rinku Jhamta ◽  
Harsimran Kaur
Keyword(s):  
Plant Extract ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Natural Antioxidants ◽  
Essential Elements ◽  
Antioxidant Potential ◽  
Antidiabetic Activity ◽  
Phytochemical Analysis ◽  
Zanthoxylum Armatum

The present study was designed to evaluate the antidiabetic and antioxidant potential of methanolic extract of Zanthoxylum armatum leaves using in vitro approaches. The concentration of plant extract that inhibited 50% (IC50) of alpha amylase was found to be 89.37±4.68 ?g/ml which is higher than standard. Results of this study shows that 2,2-diphenyl-1-picrylhydrazyl scavenging test show high radical scavenging activity as compared to hydrogen peroxide scanvenging method with IC50 Value of 57.83 ?g/ml and 79.13 ?g/ml, respectively. Plant extract found to exhibit enormous amount of phenols and flavonoid content i.e., 140.71 mg GAE/g and 88.53 mg of Quercetin/g of extract respectively. Further phytochemical analysis revealed that plant exhibit glycosides, alkaloids, terpenoids, flavonoids, saponin and tannin that are frequently implicated as having antidiabetic effects. Elemental analysis revealed the presence of essential elements ‘Mg’, ‘Mn’, ‘Zn’, ‘Fe’, ‘K’, ‘P’, ‘Ca’, ‘Cu’, ‘Mo’ and ‘Ni’ known to play role in regulating blood glucose. It could be speculated that the observed antidiabetic activity of Z. armatum might be related to the presence of these phytochemicals, phenolic compounds as well as mineral elements which found to be the important constituent of Z. armatum. These results indicate that Z. armatum could be an excellent source of natural antioxidants and exhibited antidiabetic activity.

scholarly journals Assessment of antioxidant potential and acute toxicity studies of whole plant extract of pergularia daemia (Forsk)

2015 ◽  
Vol 22 (1) ◽  
pp. 54 ◽  
Author(s):  
Sankaran Mirunalini ◽  
Veluchamy Vaithiyanathan
Keyword(s):  
Acute Toxicity ◽  
Plant Extract ◽  
Antioxidant Potential ◽  
Toxicity Studies ◽  
Whole Plant

scholarly journals Determination of Antioxidant and Oxidant Potentials of Thymbra spicata Collected from Duhok-Iraq

2020 ◽  
Vol 8 (5) ◽  
pp. 1171-1173
Author(s):  
Falah Saleh Mohammed ◽  
Ali Erdem Şabik ◽  
Emre Sevindik ◽  
Mustafa Pehlivan ◽  
Mustafa Sevindik
Keyword(s):  
Oxidative Stress ◽  
Natural Resource ◽  
Plant Extract ◽  
Antioxidant Potential ◽  
Stress Index ◽  
Oxidative Stress Index ◽  
Aerial Parts ◽  
And Oxidative Stress ◽  
Thymbra Spicata

In this study, antioxidant, oxidant and oxidative stress index of Thymbra spicata L. collected from Duhok (Iraq) region were determined. The aerial parts of the plant were extracted with ethanol. Rel Assay Diagnostics kits were used for detect TAS, TOS and OSI values. As a result of the studies, it was determined that TAS value of plant extract was determined 8.399±0.102, TOS value was 6.530±0.115 and OSI value was 0.078±0.001. As a result, it was determined that T. spicata has high antioxidant potential and in this context, can be used as a natural resource.

scholarly journals Antibacterial and antioxidant potential of biosynthesized copper nanoparticles mediated through Cissus arnotiana plant extract

2019 ◽  
Vol 197 ◽  
pp. 111531 ◽  
Author(s):  
S. Rajeshkumar ◽  
Soumya Menon ◽  
S. Venkat Kumar ◽  
Murtaza M. Tambuwala ◽  
Hamid A. Bakshi ◽  
...  
Keyword(s):  
Copper Nanoparticles ◽  
Plant Extract ◽  
Antioxidant Potential
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