scholarly journals MR-guided focused ultrasound surgery: A novel non-invasive technique in the treatment of adenomyosis –18 month's follow-up of 12 cases

2019 ◽  
Vol 29 (3) ◽  
pp. 284
Author(s):  
Bhawna Dev ◽  
Sameera Gadddam ◽  
Mitesh Kumar ◽  
Suresh Varadarajan
Keyword(s):  
Focused Ultrasound ◽  
Invasive Technique ◽  
Ultrasound Surgery ◽  
Non Invasive ◽  
Focused Ultrasound Surgery

scholarly journals Updated Costs of Uterine Fibroid Treatments Including Focused Ultrasound Surgery

2018 ◽  
Author(s):  
Bijan J. Borah ◽  
Elizabeth A. Stewart
Keyword(s):  
Magnetic Resonance ◽  
Focused Ultrasound ◽  
Treatment Options ◽  
Uterine Fibroids ◽  
Reproductive Age ◽  
Invasive Treatment ◽  
Ultrasound Surgery ◽  
Non Invasive ◽  
Focused Ultrasound Surgery ◽  
Reproductive Age Women

Uterine leiomyomas (fibroids) affect 20–40% of reproductive age women and are the major indication for hysterectomy. Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) is a new, potentially disruptive, non-invasive and uterine-sparing treatment option that has been shown to yield similar or better clinical outcomes than other uterine-sparing interventions. However, the costs of MRgFUS and other minimally-invasive treatment options have not been studied using US practice data. This study attempts to fill this void. And since uterine fibroids are the first FDA-approved indication for MRgFUS treatment, this study may also have implications for other indications which are now investigational.

scholarly journals Non-invasive focal therapy of organ confined prostate cancer with magnetic resonance guided focused ultrasound surgery

2015 ◽  
Vol 3 (S1) ◽  
Author(s):  
Alessandro Napoli ◽  
Fulvio Zaccagna ◽  
Pier Luigi Di Paolo ◽  
Francesco Sandolo ◽  
Carola Palla ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Magnetic Resonance ◽  
Focused Ultrasound ◽  
Focal Therapy ◽  
Ultrasound Surgery ◽  
Non Invasive ◽  
Focused Ultrasound Surgery

scholarly journals Focused Ultrasound Surgery Applications in Treating Vulvar Non-neoplastic Epithelial Disorders

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Felix Wu Shun Wong ◽  
Chengzhi Li
Keyword(s):  
Skin Lesion ◽  
Alternative Treatment ◽  
Focused Ultrasound ◽  
Intraepithelial Neoplasia ◽  
Vulvar Intraepithelial Neoplasia ◽  
Preparation Technique ◽  
Ultrasound Surgery ◽  
Non Invasive ◽  
Focused Ultrasound Surgery ◽  
Surgical Treatments

: Vulvar intraepithelial neoplasia is a premalignant skin lesion of the vulva that often presents with severe vulvar pruritus, pain, and psychosexual disorders. The technology of non-invasive focused ultrasound surgery has improved over the years. Today its potential to treat these irritating diseases noninvasively is a relatively new area of clinical research interest. Increasing studies in China revealed that FUS treatment is effective and safe. This paper describes the preparation, technique, postoperative care, and results of this focused ultrasound surgery for treating vulvar non-neoplastic epithelial disease. Therefore it could be a future alternative treatment for benign vulvar diseases, replacing many invasive surgical treatments.

scholarly journals Preliminary experience with a transcranial magnetic resonance–guided focused ultrasound surgery system integrated with a 1.5-T MRI unit in a series of patients with essential tremor and Parkinson’s disease

2018 ◽  
Vol 44 (2) ◽  
pp. E7 ◽  
Author(s):  
Domenico Gerardo Iacopino ◽  
Cesare Gagliardo ◽  
Antonella Giugno ◽  
Giuseppe Roberto Giammalva ◽  
Alessandro Napoli ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Magnetic Resonance ◽  
Essential Tremor ◽  
Focused Ultrasound ◽  
Ultrasound Surgery ◽  
Focused Ultrasound Surgery ◽  
Stereotactic Frame ◽  
Clinical Series

OBJECTIVETranscranial magnetic resonance–guided focused ultrasound surgery (tcMRgFUS) is one of the emerging noninvasive technologies for the treatment of neurological disorders such as essential tremor (ET), idiopathic asymmetrical tremor-dominant Parkinson’s disease (PD), and neuropathic pain. In this clinical series the authors present the preliminary results achieved with the world’s first tcMRgFUS system integrated with a 1.5-T MRI unit.METHODSThe authors describe the results of tcMRgFUS in a sample of patients with ET and with PD who underwent the procedure during the period from January 2015 to September 2017. A monolateral ventralis intermedius nucleus (VIM) thalamic ablation was performed in both ET and PD patients. In all the tcMRgFUS treatments, a 1.5-T MRI scanner was used for both planning and monitoring the procedure.RESULTSDuring the study period, a total of 26 patients underwent tcMRgFUS thalamic ablation for different movement disorders. Among these patients, 18 were diagnosed with ET and 4 were affected by PD. All patients with PD were treated using tcMRgFUS thalamic ablation and all completed the procedure. Among the 18 patients with ET, 13 successfully underwent tcMRgFUS, 4 aborted the procedure during ultrasound delivery, and 1 did not undergo the tcMRgFUS procedure after stereotactic frame placement. Two patients with ET were not included in the results because of the short follow-up duration at the time of this study. A monolateral VIM thalamic ablation in both ET and PD patients was performed. All the enrolled patients were evaluated before the treatment and 2 days after, with a clinical control of the treatment effectiveness using the graphic items of the Fahn-Tolosa-Marin tremor rating scale. A global reevaluation was performed 3 months (17/22 patients) and 6 months (11/22 patients) after the treatment; the reevaluation consisted of clinical questionnaires, neurological tests, and video recordings of the tests. All the ET and PD treated patients who completed the procedure showed an immediate amelioration of tremor severity, with no intra- or posttreatment severe permanent side effects.CONCLUSIONSAlthough this study reports on a small number of patients with a short follow-up duration, the tcMRgFUS procedure using a 1.5-T MRI unit resulted in a safe and effective treatment option for motor symptoms in patients with ET and PD. To the best of the authors’ knowledge, this is the first clinical series in which thalamotomy was performed using tcMRgFUS integrated with a 1.5-T magnet.

scholarly journals Magnetic Resonance-guided Focused Ultrasound Treatment for Uterine Fibroids: First Study in Indian Women

2012 ◽  
Vol 2 ◽  
pp. 74 ◽  
Author(s):  
Shrinivas B. Desai ◽  
Abhijit A. Patil ◽  
Rahul Nikam ◽  
Ajinkya S. Desai ◽  
Vrushali Bachhav
Keyword(s):  
Magnetic Resonance ◽  
Adverse Events ◽  
Focused Ultrasound ◽  
Uterine Fibroids ◽  
Ultrasound Surgery ◽  
Indian Women ◽  
Safety And Efficacy ◽  
Focused Ultrasound Surgery ◽  
The Mean

Objectives: To study the results of magnetic resonance-guided focused ultrasound surgery (MRgFUS) treatment carried out on Indian patients in our Hospital. Materials and Methods: Fifty Indian women (mean age = 36.2 ± 8.3 years) were treated for fibroids as outpatients using the ExAblate MRgFUS system (InSightec). Non-perfused volumes (NPVs) were measured immediately after treatment to calculate the treatment outcomes. A validated symptom-specific questionnaire to record their symptoms prior to treatment and six months following treatment was completed by patients. The size of the fibroids was measured on the day of the treatment and during the 6-month checkup to calculate shrinkage. Adverse events during and following treatment were recorded and monitored. Results: The average NPV ratio measured after the treatment was 88% ± 6%, indicative of high ablated fibroid tissue. Prior to treatment, the mean Symptoms Severity Score was 56.9 ± 4.8 (n = 50), which is indicative of highly symptomatic patients. Six months following treatment, there was an average fibroid shrinkage of 30% ± 11%, and a significant decrease in the mean score to 28.6 ± 6.0 (n = 50) (P < 0.001). There were no reports of serious or unexpected adverse events at any point during treatment or during the follow-up period from any of the 50 women treated in the current study. Conclusions: The current results obtained after 6 months of treatment corroborated previous data on the safety and efficacy of MRgFUS for treating uterine fibroids. This is the first publication that provides such data for a large cohort of Indian women.

Magnetic resonance-guided focused Ultrasound surgery for treatment of osteoid osteoma: How do we do it?

2021 ◽  
Vol 3 (1) ◽  
pp. 159-162
Author(s):  
Khariah Mat Nor ◽  
Marlina Tanty Ramli Hamid ◽  
Basri Johan Jeet Abdullah ◽  
Vivek Ajit Singh
Keyword(s):  
Magnetic Resonance ◽  
Osteoid Osteoma ◽  
Severe Pain ◽  
Bone Pain ◽  
Focused Ultrasound ◽  
Joint Involvement ◽  
Invasive Technique ◽  
Appendicular Skeleton ◽  
Ultrasound Surgery ◽  
Focused Ultrasound Surgery

Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) is an increasingly popular non-invasive technique for treatment of severe pain produced by soft tissue, solid or bone tumours. MRgFUS used targeted thermal ablation technique to control moderate to severe pain. Osteoid osteoma is a small benign, highly vascular tumour, composed of osteoid and woven bone, most commonly affect the appendicular skeleton. Bony spine involvement can produce painful scoliosis, while intra-articular joint involvement can cause irreversible joint damage. Clinical presentation is local bone pain which typically worsen at night and with increased activity. Conventional standard treatment of osteoid osteoma is analgesic or surgical intervention. Under conservative medical treatment, the patient needs to be on long term analgesic, e.g. salicylates, where well-known reported complications include renal tubular acidosis and gastric ulcer. The standard surgical treatment is curettage. However, this carry the risk of bleeding, infection and tissue damage. Minimally invasive radiofrequency ablation (RFA) or cryoablation which are the current treatment of choice also carry the risk of tumour rupture and bleeding. We present a case of severe bone pain from benign bone tumor (osteoid osteoma), successfully treated with noninvasive Magnetic MRgFUS.

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