scholarly journals Focused Ultrasound Surgery Applications in Treating Vulvar Non-neoplastic Epithelial Disorders

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Felix Wu Shun Wong ◽  
Chengzhi Li

: Vulvar intraepithelial neoplasia is a premalignant skin lesion of the vulva that often presents with severe vulvar pruritus, pain, and psychosexual disorders. The technology of non-invasive focused ultrasound surgery has improved over the years. Today its potential to treat these irritating diseases noninvasively is a relatively new area of clinical research interest. Increasing studies in China revealed that FUS treatment is effective and safe. This paper describes the preparation, technique, postoperative care, and results of this focused ultrasound surgery for treating vulvar non-neoplastic epithelial disease. Therefore it could be a future alternative treatment for benign vulvar diseases, replacing many invasive surgical treatments.

2018 ◽  
Author(s):  
Bijan J. Borah ◽  
Elizabeth A. Stewart

Uterine leiomyomas (fibroids) affect 20–40% of reproductive age women and are the major indication for hysterectomy. Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) is a new, potentially disruptive, non-invasive and uterine-sparing treatment option that has been shown to yield similar or better clinical outcomes than other uterine-sparing interventions. However, the costs of MRgFUS and other minimally-invasive treatment options have not been studied using US practice data. This study attempts to fill this void. And since uterine fibroids are the first FDA-approved indication for MRgFUS treatment, this study may also have implications for other indications which are now investigational.


2015 ◽  
Vol 3 (S1) ◽  
Author(s):  
Alessandro Napoli ◽  
Fulvio Zaccagna ◽  
Pier Luigi Di Paolo ◽  
Francesco Sandolo ◽  
Carola Palla ◽  
...  

2010 ◽  
Vol 06 (02) ◽  
pp. 76
Author(s):  
Pedro Valero ◽  
Emilio Gomez-Gonzalez ◽  
Araceli Sabino ◽  
Maria Valero ◽  
Jerónimo Suárez-Ramos ◽  
...  

Magnetic-resonance-guided focused ultrasound surgery (MRgFUS) is a novel non-invasive surgical procedure in the field of image-guided interventions. Thermal ablation is achieved using focused ultrasound beams controlled by magnetic resonance. Energy delivered to focal (sonication) spots allows for a very precise and controlled increase in temperature, resulting in coagulative necrosis of target tissue. 3D visualisation and temperature monitoring allow for realtime feedback and control. Post-treatment evaluation is performed in the same session. Since there is no dose limit, the procedure can be repeated as needed. An expanding number of applications are currently being developed in oncology. This article reviews the fundamentals and initial clinical data, including palliative treatment of pain in bone metastases, breast cancer, diseases of the central nervous system, prostate cancer, hepatocellular carcinoma and targeted drug delivery.


2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Akiko Matsutani ◽  
Yoshimi Ide ◽  
Sakiko Miura ◽  
Masafumi Takimoto ◽  
Sadao Amano ◽  
...  

Abstract Objective This report describes the first clinical experience with magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) using the ExAblate 2100 system for non-invasive breast cancer. Methods Two women with non-invasive breast cancer underwent MRgFUS treatment. One week after the MRgFUS treatment, US-guided vacuum-assisted biopsy was performed for the ablated lesions at the same time as breast-conserving surgery. Results The patients experienced good cosmetic outcomes and did not experience any severe adverse events, such as skin burns. Pathological examination of the surgical specimens revealed a few degenerated intraductal lesions around the breast biopsy markers. Conclusion Performing MRgFUS with the new ExAblate 2100 system appears to be safe and feasible. The histopathological results revealed that adequate ultrasound energy in the appropriate location can induce tumor necrosis.


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