scholarly journals Comparison of hematological parameters for signs of anemia among participants with and without chronic periodontitis: A cross-sectional study

2019 ◽  
Vol 17 (1) ◽  
pp. 4
Author(s):  
Faizia Rahman ◽  
Sarita Parihar ◽  
NK Sharma ◽  
Atul Bhatnagar ◽  
Dhiraj Kishore ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Hematological Parameters ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Hematological alteration among visceral leishmaniasis patients attending in Western Tigrai, Ethiopia, 2018/2019: A cross-sectional study

2020 ◽  
Author(s):  
Gebremedhin Gebremichail ◽  
Brhane Tesfanchal ◽  
Getachew Belay ◽  
Gebreslassie Gebremariam ◽  
Gebreyohans Teklehaymanot ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Blood Cell ◽  
Hematological Parameters ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Control Groups ◽  
Cross Sectional ◽  
Red Cell Indices ◽  
Hematological Abnormalities

Abstract Background: Hematological abnormalities are common in visceral leishmaniasis patients, which is one of the main public health problems worldwide. The most common hematological abnormalities are anemia, leucopenia and thrombocytopenia. Therefore, this study aimed to assess the hematological alteration among visceral leishmaniasis patients attending Western Tigrai, Ethiopia, 2019. Method: Hospital based comparative cross sectional study was conducted from November 2018 to March 2019 in Western Tigrai, Ethiopia. A total of 100 Visceral Leishmaniasis patients and 100 control groups were included in this study. Blood was collected and analyzed by mindray BC-5800 hematology analyzer. Data was entered and analyzed using Statistical package for social science version 23. Student independent t-test was used for data analysis. P value <0.05 was considered as statistically significant at 95% confidence level. Result: From the total 100 visceral leishmaniasis patients the following abnormalities were reported: 96(96%) anemia, 95(95%) leucopenia, 92(92%) neutropenia, 73(73%) Lymphopenia, 45(45%) eosinopenia and 97(97%) had thrombocytopenia. Red blood cell, hemoglobin, hematocrit, red cell indices and platelet were significantly lower (p<0.05) in visceral leishmaniasis patients compared with the control groups. Similarly the total White blood cell, neutrophil, lymphocyte, eosinophil and basophil count were significantly lower (p<0.05) in visceral leishmaniasis patients compared with the control groups. Conclusion: The major changes in peripheral blood of patient with visceral leishmaniasis are reduced number of red blood cells, reduction in leukocytes and decreased platelet count. Visceral leishmaniasis patients presented with anemia, leucopenia and thrombocytopenia. So this finding indicates that visceral leishmaniasis causes alterations of hematological parameters. Key words: Amastigote, Anemia, Hematological Parameters, Promastigote, Visceral leishmaniasis, Ethiopia .

scholarly journals Hematological Parameters and Hemozoin-Containing Leukocytes and Their Association with Disease Severity among Malaria Infected Children: A Cross-Sectional Study at Pawe General Hospital, Northwest Ethiopia

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Muluken Birhanu ◽  
Yaregal Asres ◽  
Wondimagegn Adissu ◽  
Tilahun Yemane ◽  
Endalew Zemene ◽  
...  
Keyword(s):  
General Hospital ◽  
Severe Malaria ◽  
Disease Severity ◽  
Hematological Parameters ◽  
Study Participant ◽  
Cross Sectional Study ◽  
Hematological Parameter ◽  
Sectional Study ◽  
Cross Sectional ◽  
Study Participants

Hematological parameter changes are the most common complications in malaria. We aimed to determine the hematological parameters and hemozoin-containing leukocytes and their association with disease severity in malaria infected children aged between 1 and 15 years. A facility-based cross-sectional study was conducted at Pawe General Hospital from July 31 to December 30, 2014. Demographic and clinical data were collected using structured questionnaire. Blood specimen was collected from each study participant for hematological investigations. Data were analyzed using SPSS version 20. The overall prevalence of anemia was 40.3%, most of which were mildly anemic. Leukocytosis was found in 15.4% of study participants. More than a fourth (27%) of the children had severe malaria. Hemozoin-containing monocytes and neutrophils were found in 80.1% and 58.9% of the study participants, respectively. Under-five years of age (AOR = 3.01, 95% CI: 1.83–7.39,P<0.001), leukocytosis (AOR = 3.20, 95% CI: 1.65–6.24,P=0.001), mean hemozoin-containing monocytes >5% (AOR = 6.26, 95% CI: 2.14–14.29,P<0.001), mean hemozoin-containing neutrophils >5% (AOR = 7.93, 95% CI: 3.09–16.86,P<0.001), and high density parasitemia (AOR = 1.90, 95% CI: 1.13–3.18,P=0.015) were associated with severe malaria. Hemozoin-containing leukocytes, leukocytosis, and other identified associated factors should be considered for proper management of children with severe malaria.

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