scholarly journals Hematological Parameters and Hemozoin-Containing Leukocytes and Their Association with Disease Severity among Malaria Infected Children: A Cross-Sectional Study at Pawe General Hospital, Northwest Ethiopia

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Muluken Birhanu ◽  
Yaregal Asres ◽  
Wondimagegn Adissu ◽  
Tilahun Yemane ◽  
Endalew Zemene ◽  
...  

Hematological parameter changes are the most common complications in malaria. We aimed to determine the hematological parameters and hemozoin-containing leukocytes and their association with disease severity in malaria infected children aged between 1 and 15 years. A facility-based cross-sectional study was conducted at Pawe General Hospital from July 31 to December 30, 2014. Demographic and clinical data were collected using structured questionnaire. Blood specimen was collected from each study participant for hematological investigations. Data were analyzed using SPSS version 20. The overall prevalence of anemia was 40.3%, most of which were mildly anemic. Leukocytosis was found in 15.4% of study participants. More than a fourth (27%) of the children had severe malaria. Hemozoin-containing monocytes and neutrophils were found in 80.1% and 58.9% of the study participants, respectively. Under-five years of age (AOR = 3.01, 95% CI: 1.83–7.39,P<0.001), leukocytosis (AOR = 3.20, 95% CI: 1.65–6.24,P=0.001), mean hemozoin-containing monocytes >5% (AOR = 6.26, 95% CI: 2.14–14.29,P<0.001), mean hemozoin-containing neutrophils >5% (AOR = 7.93, 95% CI: 3.09–16.86,P<0.001), and high density parasitemia (AOR = 1.90, 95% CI: 1.13–3.18,P=0.015) were associated with severe malaria. Hemozoin-containing leukocytes, leukocytosis, and other identified associated factors should be considered for proper management of children with severe malaria.

2016 ◽  
Vol 28 (4) ◽  
pp. 389-396 ◽  
Author(s):  
Henry Namme Luma ◽  
Servais Albert Fiacre Bagnaka Eloumou ◽  
Ellis Atemlefeh Fualefeh-Morfaw ◽  
Agnes Malongue ◽  
Elvis Temfack ◽  
...  

While gastrointestinal disease is common among HIV infected individuals, the prevalence and distribution of ano-rectal pathology has not been well studied in our setting. The objective of this study therefore was to determine the prevalence and determinants of ano-rectal pathology in HIV infected patients attending the Douala General Hospital HIV treatment centre. A hospital-based cross-sectional study was undertaken. We collected socio-demographic, clinical and laboratory data using a structured questionnaire and patients’ files. Each study participant had a full physical and ano-rectal examination. We further studied factors associated with having at least one ano-rectal lesion by logistic regression reporting odds ratios (ORs) and their 95% confidence intervals (CI). We included 390 HIV infected patients. The mean age was 41 (SD: 8) years and 48% were men. Median duration since HIV diagnosis was 3 (interquartile range: 2–5) years and median CD4 cell count was 411 (interquartile range: 234–601) cells/mm3. Prevalence of ano-rectal pathology was 22.8% (95% CI: 18.7–27.3). Hemorrhoids and proctitis were most common lesions found; each in 10% of patients. From multivariate logistic regression, factors associated with ano-rectal pathology were CD4 < 350 cells/ml (OR: 2.1, 95% CI: 1.1–4.2), not on highly active antiretroviral therapy (OR: 2.2, 95% CI: 1.1–4.6), inpatient (OR: 2.3, 95% CI: 1.2–4.3), ano-rectal intercourse (OR: 5.0, 95% CI: 1.7–15.1), and more than one sexual partner (OR: 2.4, 95% CI: 1.3–4.2). Ano-rectal pathology is common amongst HIV infected patients. Care givers should actively investigate and treat them as this will improve the quality of life of people living with HIV/AIDS.


Author(s):  
Akshaya V Naik ◽  

Introduction: Occupational hazards are the risks to life or functioning of an individual that is inherently associated with his occupation or working environment which can have deleterious effect on the individual’s health and his working efficiency. Petrol pump attendants are one such category of workers who are constantly exposed to various hazards at their workplace. Methodology: A cross sectional study was conducted from November- December 2018 among 7 petrol pumps located in the Panjim city. Census method was used for sampling. Ethical approval was obtained from the Institutional Ethics Committee. Data was collected using pre-designed semi structured questionnaire. Data was collected using Epicollect 5 mobile app and analyzed using SPSS version 22. Result: Musculoskeletal pain was the most common health problem perceived by the study participants (49.3%) followed by frequent headaches (26.7%), eye irritation (22.7%) and stuffy nose (18.7%). Fuel spillage over skin (68%), extreme weather conditions (37.3%), fuel spillage in the eyes (32%) were the common hazards reported by the participants. None of the study participant was seen wearing goggles, mask or gloves for their personal safety. 73% of the study participants felt that the Personal Protective Equipment (PPE) should be made available for their safety. 22.7% of the study participants had high blood pressure (>140/90mmHg) at the time of interview. Conclusion: This study highlights the most common illnesses experienced by the study subjects at their work place. Provision of PPE to every worker working on the petrol station with periodic medical checkups is required.


2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Kassahun Fikadu ◽  
Negussie Boti ◽  
Birtukan Tadesse ◽  
Dureti Mesele ◽  
Emenet Aschenaki ◽  
...  

Background. Episiotomy is the most common obstetric procedure, performed when the clinical circumstances place the patient at a high risk of high-degree laceration. However, episiotomy should be done with judicious indication to lower perineal laceration with fewer complications. Despite its adverse effects, the magnitude of episiotomy is increasing due to different factors. Therefore, this study is aimed at determining the recent magnitude of episiotomy and at identifying associated factors among women who gave delivery in Arba Minch General Hospital, Southern Ethiopia. Methods. An institution-based cross-sectional study was conducted from December 15, 2018, to January 30, 2019. A systematic random sampling technique was used to select study participants. A semistructured questionnaire was used to collect data. This was supplemented with a review of the labor and delivery records. Binary and multivariable logistic regression analyses were performed to identify factors associated with the magnitude of episiotomy. P value ≤ 0.05 was used to determine the level of statistically significant variables. Results. The magnitude of episiotomy was found to be 272 (68.0%) with 95%CI=64.0‐72.5. Women who attended secondary education [AOR=10.24, 95%CI=2.81‐37.34], women who attended college and above [AOR=4.61, 95%CI=1.27‐16.71], birth weight≥3000 g [AOR=4.84, 95%CI=2.66‐8.82], primipara [AOR=4.13, 95%CI=2.40‐7.12], being housewife occupants [AOR=3.43, 95%CI=1.20‐9.98], married women [AOR=2.86, 95%CI=1.40‐5.84], and body mass index<25 kg/m2 [AOR=2.85, 95%CI=1.50‐5.44] were independent variables found to have significant association with episiotomy. Conclusion. The magnitude of episiotomy was 68.0% which is higher than the recommended practice by WHO (10%). The study participants’ occupational status, marital status, educational status, parity, birth weight, and BMI were significantly associated with the magnitude of episiotomy in the study area. Therefore, to reduce the rate of episiotomy, it is better to have periodic training for birth attendants regarding the indication of episiotomy.


Author(s):  
Nilofur Banu ◽  
Kalaivani Annadurai ◽  
Karnaboopathy Ranganathan

Background: Health seeking behavior is an important decision in health care management and it becomes more relevant among underprivileged populations like urban slums. The objectives of the study was to find out the morbidity pattern, health care seeking behaviours , the morbidity pattern its determinants among urban slum dwellers in Chennai.Methods: This descriptive cross sectional study was conducted among 400 respondents of Nallakuppam slum in Chennai by systematic random sampling method from October 2017 to October 2019. A semi structured schedule was used to collect information among them after their valid informed consent. Descriptive statistics such as frequency and percentage were used.  Chi square test was used to assess the association between factors.Results: Almost half of the study participants (53.50%) were female and 30.50% have completed high school education. Hindu was the major religion practiced and most of them belonged to lower middle socio economic class. Though majority of the study population suffered from communicable diseases like ARI and fever which might be due to overcrowding in that area, treatment seeking behavior was found to be good among the study participant suffering from non-communicable disease like DM, HTN and CHD, which showed that the type of disease played an vital role in seeking treatment among the study participants.Conclusions: Though the study participants had different choice in health care such as government, private or some time both facilities for treating their illness, trust on the health care provider played an important role in availing services from particular health care facilities.


2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Tigistu Toru ◽  
Walellign Anmut

Background. Low birth weight is defined as when a newborn weighs less than 2,500 grams within an hour of birth. Globally, it has been known that around 15.5% of newborns were below the normal level of weight at their birth and 95% of these infants lived in developing countries. The main objective of this study was to assess the prevalence and associated factors of low birth weight among newborns delivered at Butajira General Hospital, Southwest Ethiopia. Methods. An institutional-based cross-sectional study design was employed. All 196 paired study participants (newborn-mother) who were born on a one-month duration of the data collection period were included in the study. A pretested questionnaire was used to gather pertinent information about mother and newborn along with measuring newborn birth weight. Result. Majority of mothers 175 (92.1%) were aged between 20 and 34 years, and 186 (97.9%) were married. About 169 (88.9%) were protestant religion followers. This study showed that the magnitude of low birth weight among study participants was 12.5%, and factors such as maternal medical complication during pregnancy, maternal MUAC less than 23 cm, and birth interval less than 24 months were significantly associated with low birth. Conclusion. The study finding indicated that a significant number of newborns measured underweight which is below the normal level of weight at birth. The study identified factors such as maternal medical condition during pregnancy, maternal MUAC less than 23 cm, and birth interval less than 24 months. Based on study findings, we recommend health care officials, policymakers, key persons in the family, and volunteers to work on nutritional values particularly during pregnancy and before pregnancy. Spacing of birth is crucial to have healthy baby and healthy family even healthy society at large, so attention should be paid on family planning utilization.


BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e045892
Author(s):  
Solomon Feleke ◽  
Gudina Egata ◽  
Firehiwot Mesfin ◽  
Gizachew Yilak ◽  
Abebaw Molla

ObjectiveThe study aimed to assess the prevalence of stunting, wasting, underweight and associated factors in orphaned children under 5 years old.DesignA cross-sectional study.SettingGambella City, Ethiopia.ParticipantsA sample of 419 under 5 orphaned children included in the study. Eligible households with orphans had selected using a systematic random sampling method. The lottery method was used when more than one eligible study participants live in the household. An OR with 95% CI was performed to measure the strength of association between each dependent variable and independent variables. Variables with p<0.05 were declared statistically significant.Primary outcomeThe main outcome of this study was the prevalence of undernutrition among orphaned under 5 and its associated factors.ResultsPrevalence of stunting, wasting and underweight in orphan children under 5 were 12.2%, 37.8% and 21.7%, respectively. The prevalnce of wasting peaks among age group of 36–47 months (42.5%), whereas underweight peaks in 48–59 months (27.7%). Food insecurity, wealth index, family size, vitamin A supplementation, diarrhoea, fever 2 weeks before the survey, children under 5 and parents’ death were associated with undernutrition.ConclusionThe prevalence of stunting, wasting and underweight among orphan children under 5 was significantly high. Multisectoral collaborative efforts towards access to health services, improving income-generating activities, micronutrient supplementation and social support and protection targeting orphan and vulnerable populations have to be built up.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Maru Mekie ◽  
Dagne Addisu ◽  
Minale Bezie ◽  
Abenezer Melkie ◽  
Dejen Getaneh ◽  
...  

Abstract Background Preeclampsia has the greatest impact on maternal mortality which complicates nearly a tenth of pregnancies worldwide. It is one of the top five maternal mortality causes and responsible for 16 % of direct maternal death in Ethiopia. Little is known about the level of knowledge and attitude towards preeclampsia in Ethiopia. This study was designed to assess the knowledge and attitude towards preeclampsia and its associated factors in South Gondar, Northwest Ethiopia. Methods A multicenter facility-based cross-sectional study was implemented in four selected hospitals of South Gondar Zone among 423 pregnant women. Multistage random sampling and systematic random sampling techniques were used to select the study sites and the study participants respectively. Data were entered in EpiData version 3.1 while cleaned and analyzed by Statistical Package for Social Sciences (SPSS) version 23. Descriptive and inferential statistics were performed. Adjusted odds ratio with 95 % confidence interval were used to identify the significance of the association between the level of knowledge on preeclampsia and its predictors. Results In this study, 118 (28.8 %), 120 (29.3 %) of the study participants had good knowledge and a positive attitude towards preeclampsia respectively. The likelihood of having good knowledge on preeclampsia was found to be low among women with no education (AOR = 0.22, 95 % CI (0.06, 0.85)), one antenatal care visit (ANC) (AOR = 0.13, 95 % CI (0.03, 0.59)). Whereas, those who booked for ANC in the first trimester (AOR = 6.59, 95 % CI (1.43, 30.33)), gave the last birth at a health facility (AOR = 2.61, 955 CI (1.03, 6.61)), and experienced a complication during previous births (AOR = 3.67, 95 % CI (1.78, 7.57)) were more likely to be knowledgeable on preeclampsia. Conclusions No formal education and not attending four ANC visits were associated with poor knowledge of preeclampsia. While participants who visited health facilities during the first trimester, who gave birth at health facilities, and those who experienced a complication in previous births were more likely to be knowledgeable on preeclampsia. Improving the numbers of ANC visits and encouraging facility delivery are important measures to improve women’s knowledge on preeclampsia. Health education regarding preeclampsia risk factors, symptoms, and complications shall be emphasized.


2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Kessete Ayelgn ◽  
Tadesse Guadu ◽  
Atalay Getachew

Abstract Background Trachoma is an infectious disease of the eye caused by Chlamydia trachomatis and transmitted via contact with eye discharge from infected persons and leading to blindness worldwide. Children less than 9 years of age affected more seriously. The disease is common where access to water and sanitation are limited. Objective To determine the prevalence of active trachoma and associated factors among children aged 1–9 years in rural communities of Metema District, West Gondar Zone, Northwest Ethiopia. Method A community based cross-sectional study design was used to collect data from 792 children aged 1–9 years old in Metema district from April to May 2018. Multistage sampling technique was used to select the study participants. Pretested interviewer-administered structured questionnaire and eye examination using binocular loupe to differentiate trachoma cases was the data collection methods and tools. The bivariable and multivariable binary logistic regression model was employed for analysis. P-value < 0.05 was considered to declare statistical significance. Results A total of 752 children aged l-9 years were enrolled in this study with response rate of 94.9%. The overall prevalence of active trachoma among the study participants was 11.8% (95% CI, 9.5–13.9). Unprotected source of water (AOR = 4.7; 95% CI: 2.5–8.9), lower household water consumption (AOR = 2.8; 95% CI: 1.3–6.0), improper latrine utilization (AOR = 3.2; 95% CI: 1.5–6.7), and frequency of face washing once per day (AOR = 5.3; 95% CI: 1.2–26.6) were the factors significantly associated with active trachoma. Conclusion The current study revealed a lower overall prevalence of active trachoma (11.8%) than the WHO threshold prevalence (20%) used to declare it as a severe public health problem. All residents and health professional should collaborate on trachoma prevention by implementing the WHO SAFE strategy- surgery for trichiasis, antibiotics, facial cleanliness and environmental improvement for further trachoma elimination.


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