Abstract
Background
The non-prescription use of antibiotics is a major challenge faced by all nations. The practice is pronounced in developing and low-income countries where legislation and regulations are weak. The present study assessed the non-prescription use of antibiotics and associated factors in Ambo town, West Shoa, Oromiya, Ethiopia.
Methods
Institutional based cross-sectional study design supported with the qualitative study was conducted in Ambo town from February 1to March 1, 2020. Data were collected using a pre-tested semi-structured questionnaire and in-depth interview guide questions. Simple random sampling was used to select retail outlets and systematic random sampling to select study participants. The data analysis was done using SPSS and univariate and multivariate binary logistic regression analysis were performed to identify factors associated with non-prescription use of antibiotics. Thematic framework analysis was applied for the qualitative data.
Results
From a 421 study sample, a total of 399 participants were interviewed with a 94.8% response rate. Among the study participants 214 (53.6) were males, 228 (57.1%) were married, 191(47.9%) were orthodox by religion and, 343(86%) were Oromo by ethnicity. One hundred seventy two (43.1%) 95% CI= (38.6, 48.1) of the participants had used non prescribed Antibiotics. Being male [AOR = 2.21 95%CI 1.276,3.835], residing in rural area [AOR = 3.659, 95%CI 1.479, 9.054], holding Diploma[AOR = 0.120, 95% CI 0.025, 0.591], and hold BSC Degree [AOR = 0.050, 95% CI 0.007, 0.378], and being farmer [AOR = 0.034, 95% CI 0.004, 0.285] showed significant association with the non prescription use of Antibiotics.
Conclusion
This study concluded that the non-prescription use of antibiotics 172 (43.1%) was relatively high. Being male, residing in a rural area, holding a diploma, BSc Degree, and being a farmer were significantly associated with non-prescription use of antibiotics. So West Shoa Zone regulatory body should actively focus on the prevention of non-prescription use of Antibiotics through health communication and public awareness on the demerits of non-prescription use of Antibiotics