Herbal nanoemulsion in topical drug delivery and skin disorders: Green approach

2021 ◽  
Vol 10 (2) ◽  
pp. 171
Author(s):  
Chanchal Chaurasiya ◽  
Jitendra Gupta ◽  
Sachin Kumar
Author(s):  
Lena M. Thomas ◽  
Abeer H. Khasraghi

Dandruff and seborrheic dermatitis (SD) are common skin disorders affecting the scalp and extending to other body sites in the case of SD. They are associated with pruritus and scaling, causing an esthetical disturbance in the population affected.   Treatment of such conditions involves using a variety of drugs for long terms, thus optimizing drug formulation is essential to improve therapeutic efficacy and patient compliance. Conventional topical formulations like shampoos and creams have been widely used but their use is associated with disadvantages. To overcome such effects, novel topical nanotechnology-based formulations are currently under investigation. In the following article, we highlight recently published formulation approaches used to improve topical dandruff/SD therapy


2020 ◽  
Vol 315 ◽  
pp. 113771 ◽  
Author(s):  
Vamshi Krishna Rapalli ◽  
Tejashree Waghule ◽  
Neha Hans ◽  
Arisha Mahmood ◽  
Srividya Gorantla ◽  
...  

Nanomedicine ◽  
2021 ◽  
Author(s):  
Pablo Oyarzún ◽  
Eduardo Gallardo-Toledo ◽  
Javier Morales ◽  
Francisco Arriagada

Topical drug delivery is a promising approach to treat different skin disorders. However, it remains a challenge mainly due to the nature and rigidity of the nanosystems, which limit deep skin penetration, and the unsuccessful demonstration of clinical benefits; greater penetration by itself, does not ensure pharmacological success. In this context, transfersomes have appeared as promising nanosystems; deformability, their unique characteristic, allows them to pass through the epidermal microenvironment, improving the skin drug delivery. This review focuses on the comparison of transfersomes with other nanosystems (e.g., liposomes), discusses recent therapeutic applications for the topical treatment of different skin disorders and highlights the need for further studies to demonstrate significant clinical benefits of transfersomes compared with conventional therapies.


2013 ◽  
Vol 2 (4) ◽  
pp. 294-303 ◽  
Author(s):  
Thierry Benvegnu ◽  
Loïc Lemiègre ◽  
Sylvain Dalençon ◽  
Jelena Jeftić

2013 ◽  
Vol 197 (3) ◽  
pp. 519-520
Author(s):  
Paul Mills

2015 ◽  
Vol 135 (8) ◽  
pp. 791-798 ◽  
Author(s):  
Min Young Lee ◽  
Jun Ho Lee ◽  
Ho Sun Lee ◽  
Jun-Jae Choi ◽  
Jongmoon Jang ◽  
...  

Author(s):  
Asif Eqbal ◽  
Vaseem Ahamad Ansari ◽  
Abdul Hafeez ◽  
Farogh Ahsan ◽  
Mohd Imran ◽  
...  

Nanoemulsions are drug transporters for the delivery of therapeutic agents. They possess the small droplet size having the range of 20×10-9-200×10-9m. The main purpose of using Nanoemulsion is to enhance the drug bio- availability of transdermal drug delivery system. With the help of phase diagram, we can select the components of nanoemulsion depending upon formulas ratio of oil phase, surfactant/co-surfactant and water phase. Nanoemulsion directly used as a topical drug delivery in skin organs. The most useable pharmaceutical application has been developed till date to provide systemic effects to penetrating the full thickness of skin organ layer nanoemulsions can be administered through variety of routes such as percutaneous, perioral, topical, transdermal, ocular and parental administration of medicaments. Nanoemulsions are transparent and slightly opalescent. Nanoemulsion can be prepared through various methods. Nanoemulsions are transparent and slightly opalescent. Factor affecting nanoemulsions are surfactant, viscosity, lipophilic, drug content, pH, concentration of each component, and methodology of formulation. It is unfeasible to test all factors at the various levels. Design of formulation when it comes to experimental design it gives an excellent approach through reducing the time and money.


2017 ◽  
Vol 2 (4) ◽  
pp. 269-280 ◽  
Author(s):  
Vivek Dave ◽  
Renu Bala Yadav ◽  
Kriti Kushwaha ◽  
Sachdev Yadav ◽  
Swapnil Sharma ◽  
...  

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