scholarly journals Clinical spectrum of Plasmodium vivax infection, from benign to severe malaria: A tertiary care prospective study in adults from Delhi, India

2019 ◽  
Vol 9 (2) ◽  
pp. 88 ◽  
Author(s):  
SujataElizabeth Mathews ◽  
MohitM Bhagwati ◽  
Vinod Agnihotri

Author(s):  
Geeta Yadav ◽  
Geeta Pardeshi ◽  
Neelam Roy

Background: Malaria is an important public health problem in India. Severe and complicated forms of malaria are usually associated with Plasmodium falciparum species. But recently published literature suggests that Plasmodium vivax infection also presents as severe malaria. The objective was to study clinical and epidemiological profile of patients with P. vivax malaria admitted in Safdarjung hospital.Methods: A record based retrospective study was conducted in Vardhman Mahavir Medical College & Safdarjung Hospital, a tertiary care hospital in Delhi. Data were collected from all case records with ICD 10 codes for Malaria (B50-B54) for the year 2011 obtained from Medical Records Department, Safdarjung Hospital and analyzed using SPSS 21.0.Results: A total of 147 case records which had information about the test results for type of malaria infection were reviewed. Out of 147, 89 (60.5%) had P. vivax malaria. Of the 89 patients with P. vivax malaria, 47 (53%) were children and 63 (70.7%) were males. A peak in the number of inpatients was seen in September with median duration of hospital stay of 4 days and case fatality rate of 9%. A total of 56 (63%) patients had one or more severe manifestations of malaria as per WHO criteria. The most common severe manifestation was bleeding 27 (30%) followed by impaired consciousness 18 (20%).Conclusions: In more than half of the malaria patients admitted at the tertiary care centre the diagnosis was P. vivax malaria. Of them 63% patients had severe malaria as per WHO criteria.



Author(s):  
Dinesh Walia ◽  
Umang Arora ◽  
Upendra Baitha ◽  
Arvind Kumar ◽  
Piyush Ranjan ◽  
...  


2015 ◽  
Vol 14 (1) ◽  
Author(s):  
Vitor R. R. Mendonça ◽  
Ligia C. L. Souza ◽  
Gabriela C. Garcia ◽  
Belisa M. L. Magalhães ◽  
Marilda S. Gonçalves ◽  
...  


2020 ◽  
Author(s):  
Edgar Bustos-Cordova ◽  
Daniela Castillo-García ◽  
Magdalena Cerón-Rodriguez ◽  
Nadia Soler-Quiñones

Abstract Objective: From the beginning of the COVID-19 pandemic, it has become evident that the spectrum of manifestations in children is different from those seen in adults. In this study, we aimed to describe a broader clinical spectrum of COVID-19 in children.Methods: In this descriptive, prospective study, we enrolled confirmed pediatric patients with COVID-19 who presented to a pediatric tertiary care center from April to July 2020. All patients were confirmed by the SARSCoV-2 RT-PCR test, and we analyzed 24 symptoms and 25 signs.Results: We analyzed 50 patients with COVID-19. From the evaluated signs and symptoms, the most common symptoms were fever, irritability and dry cough, digestive symptoms were frequently found (24%), and the most common signs were pharyngeal hyperemia and irritability. Conclusion: Clinicians should recognize that the clinical spectrum of COVID-19 in children is wider than previously described. Although the classic signs and symptoms are frequent, digestive symptoms should raise suspicion.



2019 ◽  
Vol 7 (20) ◽  
pp. 3404-3408
Author(s):  
Novyan Lusiyana ◽  
Anggia Fitria Agustin ◽  
Asril Abdul Sa’ad

AIM: This study investigated the distribution, characteristics, clinical manifestation and severity of Malaria in East Halmahera, North Maluku. METHODS: A retrospective and an observational method were used in this study. Data were obtained through analysing medical records of malaria patients from January to December 2016. RESULTS: There were 89 malaria patients enrolled in the study. The cases infected by P. vivax only were 75 cases (84.3%), by P. falciparum only (7, 7.8%), and by both infections (7, 7.8%). The incidence of malaria was higher in July and August 2016 in Cemara Jaya district (18, 20.2%) and Baturaja district (17, 19.1%). While severe malaria was higher in children (4, 28.6%) and pregnant women 2 (100%) by P. vivax infection. CONCLUSION: Plasmodium vivax infection was higher than P. falciparum. Severe P. vivax infection was higher than P. falciparum, and most of the cases were in children and pregnant women.



2015 ◽  
Vol 3 (3) ◽  
pp. 206
Author(s):  
Dinesh Chavda ◽  
Satish Suthar ◽  
Nil Desai ◽  
Jayesh Balat ◽  
Bharti Desai


2014 ◽  
Vol 05 (05) ◽  
pp. 177-187 ◽  
Author(s):  
Sharad R. Jain ◽  
Jayesh S. Prajapati ◽  
Manjunath A. Phasalkar ◽  
Bhavesh H. Roy ◽  
Ashwal A. Jayram ◽  
...  


2020 ◽  
Author(s):  
Paola López Del-Tejo ◽  
Nadia Cubas-Vega ◽  
Cecilia Caraballo-Guerra ◽  
Bernardo Maia da Silva ◽  
Jefferson da Silva Valente ◽  
...  

Abstract Background. Malaria and HIV are two important public health issues. However, data on HIV-Plasmodium vivax co-infection (HIV/PvCo) is scarce, with most of the available data related to P. falciparum in the African region. It is unclear whether HIV can change the clinical course of Plasmodium vivax (Pv) malaria, and thereby increase the risk of complications. In this study, a systematic review of the HIV/PvCo is presented, including new cases from the Brazilian Amazon. Methods. Medical records from a tertiary care center in the Western Brazilian Amazon (2009 to 2018) were reviewed to identify HIV/PvCo hospitalized patients. Demographic, clinical and laboratory characteristics, and outcomes are reported. We also performed a systematic review of published studies on HIV/PvCo. Metadata, number of HIV/PvCo cases, demographic, clinical, and outcome data were extracted if available. Results. A total of 1048 vivax malaria patients were hospitalized in the 10-year period; 21 (2.0%) were HIV/PvCo cases, of which nine (42.9%) had AIDS-defining illnesses. For eleven (52.4%) patients, this was their first malaria infection. Seven (33.3%) patients were unaware of their HIV status and were diagnosed at hospitalization. Severe malaria criteria were found in 5 (23.8%) patients. One patient died. The systematic review provided 17 articles (12 cross-sectional or longitudinal studies and 5 case report studies). A higher prevalence of studies involved cases in African and Asian countries (35.3% and 29.4%, respectively), and the prevalence of reported co-infections ranged from 0.1 to 60%. Cases of severe malaria-HIV coinfection were not reported. Conclusion. Reports of HIV/PvCo are scarce in the literature, with only a few studies describing clinical and laboratory outcomes. Systematic screening for both co-infections are not performed, and therefore, a realistic prevalence of HIV/PvCo is absent. This study showed a low prevalence of HIV/PvCo, despite local malaria and HIV high prevalence. Even though relatively small, this is the largest case series to describe HIV/PvCo.



Sign in / Sign up

Export Citation Format

Share Document