A Randomized, Prospective, Placebo/Controlled Study for the Effect of Phenazopyridine HCl on Pain Perception following Cystoscopy

2006 ◽  
Vol 47 (1) ◽  
pp. 97
Author(s):  
Tae Nam Kim ◽  
Moon Kee Chung
Keyword(s):  
Pain Perception ◽  
Controlled Study

scholarly journals Oxytocin and positive couple interaction affect the perception of wound pain in everyday life

2020 ◽  
Vol 16 ◽  
pp. 174480692091869
Author(s):  
Ann-Christin Pfeifer ◽  
Paul Schroeder-Pfeifer ◽  
Ekaterina Schneider ◽  
Maren Schick ◽  
Markus Heinrichs ◽  
...  
Keyword(s):  
Social Interaction ◽  
Everyday Life ◽  
Hierarchical Linear Modeling ◽  
Pain Perception ◽  
Large Body ◽  
Controlled Study ◽  
Positive Interaction ◽  
Couple Interaction ◽  
Specific Effects ◽  
Positive Social Interaction

A large body of animal and human laboratory research has linked social interaction and support to pain perception, with a possible role for the neuropeptide oxytocin as a neuroendocrine mediator. However so far, it has been unclear whether these effects translate to ecologically valid everyday life behavior and pain perception. In a randomized placebo-controlled study, a standard suction blister skin wound was induced to N = 80 romantic couples (N = 160 individuals). Couples then received intranasal oxytocin or placebo twice daily and were either instructed to perform a positive social interaction (partner appraisal task, PAT) once in the laboratory and two times during the following five days, or not. During these days, all participants reported their subjective pain levels multiple times a day using ecologically momentary assessment. Results from hierarchical linear modeling suggest that pain levels within the couples were inter-related. In men, but not in women, oxytocin reduced pain levels. Women reported lower pain levels in the group of positive social interaction, while this effect did not show in men. These results suggest that intranasal oxytocin might have sex-specific effects with pain reducing effects in men but the opposite effects in women. In contrast, especially women benefit from positive interaction in terms of dampened pain levels after positive interaction. The results add to the evidence for health-beneficial effects of positive couple interaction and point to underlying neuroendocrine mechanisms in everyday life pain specifically. The sex-specific effects, in particular, may have implications for psychopharmacological treatment of pain in men and women.

scholarly journals Changes in pain following an interaction period of resistance training and green tea extract consumption in sedentary hypertensive women: impact of blood pressure swings

2019 ◽  
Vol 38 (1) ◽  
Author(s):  
Hamid Arazi ◽  
Behzad Taati ◽  
Jalal Kheirkhah ◽  
Samaneh Ramezanpour
Keyword(s):  
Blood Pressure ◽  
Resistance Training ◽  
Green Tea ◽  
Pain Threshold ◽  
Pain Perception ◽  
Green Tea Extract ◽  
Controlled Study ◽  
Training Groups ◽  
Tea Extract ◽  
The Impact

Abstract Background Changes in blood pressure (BP) may affect pain. However, the interaction effect of resistance training and green tea on BP and pain has not been studied. The primary aim of this study was to evaluate the impact of resistance training and green tea extract (GTE) on pain variables in hypertensive patients. Secondary aim included determining the effects of BP alterations on pain responses. Methods In a randomized, double-blind, placebo-controlled study, 30 middle-aged sedentary women were randomly divided into resistance training and green tea extract (GR, n = 8), resistance training (R, n = 8), green tea (G, n = 7), and control groups (C, n = 7). The study period consisted of 3 weeks of GTE (~ 245 mg total polyphenols) consumption twice a day followed by 6 weeks of interaction with resistance training. GR and R groups performed two circuits of training with ten repetitions at 50% of 1RM 2 days a week while other two groups had no any regular exercise training. R and C groups also received placebo capsules (maltodextrin) with the same timing. Pain threshold and perception, BP, and heart rate were recorded following the first and last session of training at rest and 5th and 15th minute. Results Pain perception of training groups after the last session was significantly higher than control conditions, and at this time, the magnitude of BP responses was lower in training groups. In proportion to pain threshold, there were no significant differences between groups. Conclusion It seems that training-induced hypotension can alter pain perception in hypertensive women through changes in baroreceptor activation.

scholarly journals Effect of Vibratory Therapy in Decreasing the Vaccination-induced Pain in Infants: Randomized Controlled Study

2021 ◽  
pp. 9-18
Author(s):  
Amar Taksande ◽  
Shruti Chaudhary ◽  
Abhilasha Singh Panwar ◽  
Aditi Jhamb ◽  
Rupesh Rao ◽  
...  
Keyword(s):  
Pain Perception ◽  
Pain Scale ◽  
The Body ◽  
Controlled Study ◽  
Control Group ◽  
Randomized Controlled ◽  
Vibration Therapy ◽  
C Fibers ◽  
Gate Control Theory ◽  
Nutritive Sucking

Background: Different non-medical therapies such as Non-nutritive sucking (NNS), oral sucrose with or without NNS (non-nutritive sucking), wrapping with thin blanket or cloth, kangaroo mother care (KMC), songs as well as multi-sensory stimulation are beneficial in pain reduction among neonates and infants.  According to the gate control theory, vibrations applied sat a site on the body block the nociceptive signals via the A???? and C fibers reducing the pain perception. When used along with many other nonpharmacological methods, This technique has been shown to minimize discomfort in pain-inducing treatments such as Intravenous cannulation, vaccines, heel prick, etc. The primary purpose of this study is to analyze vibrational therapy effects on infants  pain perception, thereby, providing evidence for a better pain management strategy in vaccination centers. Objective: To determine the efficacy of vibration therapy on pain perception by infants during vaccine administration. Material and Methods:  Out of total 90 eligible healthy infants who come for routinely immunization will be given either vibrational therapy (interventional group) or breastfeeding(control therapy) after doing randomization in this randomized controlled trial. The baseline vitals include cardiac rate (HR), respiratory rate (RR), and oxygen (SpO2) will be recorded before, during, and after vaccination during this treatment. Similarly, we will report Visual analog scales (VAS), Neonatal Infant Pain Scale (NIPS), and Wong-Baker FACES Pain Rating Scale, Modified Behavioral Pain Scale (MBPS)  after giving the vaccine to the infant. Results: After completion of the study we will come to know the effect of vibratory therapy on pain control. The pain intensity with the help of the NIPS score will get less in the vibratory group than in the control group. The level of distress by using the Color Analogue Scale, MBPS scale, and FLACC scale, during the vaccine-related procedure will get a lower score in the infants  who has taken vibratory therapy than the control group. Conclusion: study will probably give us information about vibration therapy, which will be an effective method for managing the pain after vaccination in infants.

Pain perception during outpatient cystoscopy: a prospective controlled study

2014 ◽  
Vol 173 ◽  
pp. 101-105 ◽  
Author(s):  
Gülen Yerlikaya ◽  
Thomas Laml ◽  
Ksenia Elenskaia ◽  
Engelbert Hanzal ◽  
Heinz Kölbl ◽  
...  
Keyword(s):  
Pain Perception ◽  
Controlled Study ◽  
Prospective Controlled Study

Possible Mechanisms of Pain Perception in Patients with Episodic Tension-Type Headache. A New Experimental Model of Myofascial Pain

Cephalalgia ◽  
2004 ◽  
Vol 24 (6) ◽  
pp. 466-475 ◽  
Author(s):  
H Mørk ◽  
M Ashina ◽  
L Bendtsen ◽  
J Olesen ◽  
R Jensen
Keyword(s):  
Pain Perception ◽  
Myofascial Pain ◽  
Tension Type Headache ◽  
Human Model ◽  
Controlled Study ◽  
Prostaglandin E ◽  
Pain Response ◽  
Prolonged Pain ◽  
Type Headache ◽  
Double Blinded

A new experimental human model of myofascial pain using intramuscular infusion of a combination of bradykinin, serotonin (5-hydroxytryptamine), histamine, and prostaglandin E2 was applied to patients with episodic tension-type headache (ETTH) in order to examine pain perception. Fifteen patients with ETTH and 15 healthy controls completed the randomized, balanced, double-blinded, placebo-controlled study. Pain intensity, punctate hyperalgesia and allodynia, and pain quality were recorded. The combination induced a moderate and prolonged pain in both patients (median 51 min) ( P = 0.001) and controls (median 22 min) ( P = 0.001). Patients reported more pain than controls both after the combination ( P = 0.045) and after placebo ( P < 0.001). The McGill pain score [PRI(R)] was significantly higher in patients ( P = 0.002) and in controls ( P = 0.001), whereas pain quality and hyperalgesia were similar after the combination compared with placebo in the two groups. Due to side-effects nine subjects did not complete the study. The increased pain response, but similar qualitative pain perception, in ETTH patients may be explained by sensitization of peripheral nociceptors even though central mechanisms may also be involved.

scholarly journals Comparison of Pain Perception and Latency with Alkalinization of 2% Lidocaine Using 8.4% Sodium Bicarbonate: A Randomized Controlled Study

2019 ◽  
Vol 10 (6) ◽  
pp. 454-456
Author(s):  
Vallala Pranitha ◽  
Tapaswi Singh ◽  
Kocherlakota S Dwijendra ◽  
Gali Nagarjuna ◽  
Zafaerah Sultana ◽  
...  
Keyword(s):  
Sodium Bicarbonate ◽  
Pain Perception ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Randomized Controlled

Effects of Shock-Absorbing Insoles During Transition from Natural Grass to Artificial Turf in Young Soccer Players

2014 ◽  
Vol 104 (5) ◽  
pp. 444-450 ◽  
Author(s):  
Søren Kaalund ◽  
Pascal Madeleine
Keyword(s):  
Pain Intensity ◽  
Pain Perception ◽  
Intervention Group ◽  
Protective Role ◽  
Soccer Players ◽  
Controlled Study ◽  
Control Group ◽  
Artificial Turf ◽  
Natural Grass ◽  
Artificial Grass

Background Playing soccer on artificial turf can provoke pain in young players. Using shock-absorbing insoles (SAIs) can result in decreased pain perception. We sought to investigate the pain and comfort intensity experienced during the switch from natural grass to third-generation artificial turf and with the use of SAIs on artificial turf during training in young soccer players. Methods In a prospective randomized controlled study, 75 players were included from the youth teams of U15, U17, and U19. Pain intensity and comfort were assessed after training on only grass turf for 3 months. Randomization stratified by team level and age was performed; the intervention group received SAIs, and the control group used their own insoles. Assessments were repeated after 3 weeks on artificial turf (baseline) and 3 more weeks (follow-up) on artificial turf with SAIs/usual insoles. Results Pain intensity increased and comfort decreased significantly after 3 weeks of training on artificial grass compared with natural grass (P &lt; .05). The addition of SAIs resulted in significantly reduced pain intensity compared with the usual insoles (P &lt; .05). Conclusions The switch to artificial turf is associated with less comfort and more pain during training in young soccer players. The use of SAIs led to lower pain intensity, highlighting a protective role of the insoles after 6 weeks of training on artificial turf.

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