scholarly journals Is Persistent Visual Neglect Associated with Poor Survival?

2010 ◽  
Vol 2 ◽  
pp. JCNSD.S5539
Author(s):  
M. Jehkonen ◽  
M. Laihosalo ◽  
T. Saunamäki ◽  
A-M. Koivisto ◽  
P. Dastidar ◽  
...  
Keyword(s):  
Right Hemisphere ◽  
Limited Attention ◽  
Visual Neglect ◽  
Poor Survival ◽  
Additional Information ◽  
Poor Recovery ◽  
Relationship Of ◽  
The Relationship

Background The association of visual neglect with survival after right hemisphere (RH) stroke has received only limited attention. Objective This study explores the relationship of visual neglect and its spontaneous recovery to survival in a homogenous patient group with first-ever RH stroke. Methods Fifty-one RH stroke patients who suffered an infarct between 1994 and 1997 were retrospectively followed for survival until August 31, 2009. Acute-phase neurological, neuropsychological and neuroradiological data were studied to identify predictors of survival. Results Twenty-eight patients died during the follow-up. Age, education, and poor recovery of visual neglect emerged as significant single predictors of death. The best set of predictors for poor survival in the multivariate model was poor recovery of visual neglect and low education. Conclusions Poor recovery of visual neglect is associated with long-term mortality in RH infarct patients. The follow-up of RH patients’ neuropsychological performance gives additional information about the prognosis.

Syndactyly—A Review and Long Term Results

HAND ◽  
1977 ◽  
Vol os-9 (1) ◽  
pp. 16-27 ◽  
Author(s):  
Peter M. Brown
Keyword(s):  
Surgical Treatment ◽  
Long Term Results ◽  
Anatomical Distribution ◽  
Long Term Follow Up ◽  
Relationship Of ◽  
The Relationship ◽  
Results Of Surgery

Syndactyly is classified and the principles of its surgical treatment discussed. The notes of eighty-five patients who had 222 webs between them were reviewed. A long term follow-up was carried out on thirty-two of these patients who had seventy-six clefts separated. The sexual and anatomical distribution of the syndactyly was investigated. The results of surgery were assessed including complications, and the relationship of complications to the type of graft used and the age at operation. It is suggested that complicated syndactyly is often separated at too early an age.

Focal Psychotherapy: Its Potential Impact on Psychotherapeutic Practice in Medicine

1972 ◽  
Vol 3 (4) ◽  
pp. 311-325 ◽  
Author(s):  
Paul H. Ornstein ◽  
Anna Ornstein
Keyword(s):  
Treatment Process ◽  
Practitioner Training ◽  
Therapeutic Results ◽  
Complete Treatment ◽  
Short And Long Term ◽  
Potential Impact ◽  
Relationship Of ◽  
The Relationship

A condensed illustration of a complete treatment process of “focal psychotherapy” is presented to contrast the specificity of this form of psychotherapy with nonspecific approaches. A two-year follow-up illustrates the meaning of specificity. The relationship of therapeutic results to the focal interventions is reflected in the patient's own views of his accomplishments in therapy. The theory and techniques of focal psychotherapy were originally worked out by Balint and his co-workers. The case example presented here is the basis of discussion showing how focal psychotherapy can help re-conceptualize and add precision to the theory, techniques and processes of both short- and long-term psychoanalytic psychotherapy. Such increased precision in interventions and focal aims could help leaders and general practitioner training groups to better achieve their collaborative tasks.

Blood TDP-43 Combined with Demographics Information Predicts Dementia Occurrence in Community Non-Dementia Elderly

2021 ◽  
Vol 79 (1) ◽  
pp. 301-309
Author(s):  
Lin Sun ◽  
Wei Li ◽  
Ling Yue ◽  
Shifu Xiao
Keyword(s):  
Cognitive Function ◽  
Dna Binding Protein ◽  
Blood Levels ◽  
Neurofilament Light Chain ◽  
Neurofilament Light ◽  
Dementia Patients ◽  
Relationship Of ◽  
The Relationship

Background: TAR DNA-binding protein-43 (TDP-43) and neurofilament light chain (NfL) are promising fluid biomarkers of disease progression for various dementia. Objective: We would explore whether blood levels of NfL and TDP-43 could predict the long-term progression to dementia, and the relationship of TDP-43 levels between cerebrospinal fluid (CSF) and blood. Methods: A total of 86 non-dementia elderly received 7-year follow-up, and were divided into 49 stable normal control (NC)/mild cognitive impairment (MCI) subjects, 19 subjects progressing from NC to MCI, and 18 subjects progressing from NC/MCI to dementia. Blood TDP-43 and NfL levels, and cognitive functions were measured in all subjects. Furthermore, another cohort of 23 dementia patients, including 13 AD and 10 non-AD patients received blood and CSF measurements of TDP-43. Results: In cohort 1, compared to stable NC/MCI group, there were higher levels of blood TDP-43 at baseline in subjects progressing from NC/MCI to dementia. The combination of baseline blood TDP-43 levels with demographics including age, education, and diabetes had the detection for dementia occurrence. Baseline blood levels of NfL are negatively associated with cognitive function at 7-year follow-up. In cohort 2, we found there were no relationship between CSF and blood levels of TDP-43. Moreover, the levels of TDP-43 in CSF was positively associated with the age of patients, especially in AD group. Conclusion: Single blood TDP-43 could not estimate dementia occurrence; however, TDP-43 combined with demographics has the predictive effect for dementia occurrence and NfL level is associated with a decrease of cognitive function.

A Long-term Epidemiologic Study of the Relationship between Occlusal Factors and Mandibular Dysfunction in Children and Adolescents

1987 ◽  
Vol 66 (1) ◽  
pp. 67-71 ◽  
Author(s):  
I. Egermark-Eriksson ◽  
G.E. Carlsson ◽  
T. Magnusson
Keyword(s):  
Age Groups ◽  
Epidemiologic Study ◽  
Signs And Symptoms ◽  
Strong Correlations ◽  
Psychological Traits ◽  
Masticatory System ◽  
Relationship Of ◽  
The Relationship

A longitudinal investigation of changes of signs and symptoms of man dibular dysfunction over four to five years was performed, by means of questionnaires and clinical examination, in 240 children, ages 7, 11, and 15 years at the first examination. The objective of this part of the study was to analyze correlations between some occlusal and other factors, and mandibular dysfunction. Signs and symptoms of mandibular dysfunction increased slightly in both frequency and severity but were judged to be mild in most cases. Several types of occlusal interference were frequently recorded at both examinations. Dental wear increased during the follow-up period, while the results of evaluations of motor activity and psychological traits were relatively constant. There were only a few significant correlations, most of which were weak, between the recorded variables and mandibular dysfunction, and those found were not consistent in all age groups. TMJ sounds were positively correlated with lateral deviation of the mandible between retruded contact and intercuspal position in all age groups. An attempt to analyze the longitudinal relationship of occlusal interference with signs and symptoms of mandibular dysfunction did not reveal any strong correlations. The results are interpreted as supporting the heterogeneous and multifactorial nature of functional disturbances of the masticatory system.

A Decade of Disparities in Diabetes Technology Use and HbA1c in Pediatric Type 1 Diabetes: A Trans-Atlantic Comparison

2020 ◽  
Author(s):  
Ananta Addala ◽  
Marie Auzanneau ◽  
Kellee Miller ◽  
Werner Maier ◽  
Nicole Foster ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Technology Use ◽  
Hemoglobin A1c ◽  
Diabetes Technology ◽  
Design And Methods ◽  
Relationship Of ◽  
The Relationship ◽  
Pediatric Type 1 Diabetes

<b>Objective:</b> As diabetes technology use in youth increases worldwide, inequalities in access may exacerbate disparities in hemoglobin A1c (HbA1c). We hypothesized an increasing gap in diabetes technology use by socioeconomic status (SES) would be associated with increased HbA1c disparities. <p> </p> <p><b>Research Design and Methods: </b>Participants aged <18 years with diabetes duration ≥1 year in the Type 1 Diabetes Exchange (T1DX, US, n=16,457) and Diabetes Prospective Follow-up (DPV, Germany, n=39,836) registries were categorized into lowest (Q1) to highest (Q5) SES quintiles. Multiple regression analyses compared the relationship of SES quintiles with diabetes technology use and HbA1c from 2010-2012 and 2016-2018. </p> <p> </p> <p><b>Results: </b>HbA1c was higher in participants with lower SES (in 2010-2012 & 2016-2018, respectively: 8.0% & 7.8% in Q1 and 7.6% & 7.5% in Q5 for DPV; and 9.0% & 9.3% in Q1 and 7.8% & 8.0% in Q5 for T1DX). For DPV, the association between SES and HbA1c did not change between the two time periods, whereas for T1DX, disparities in HbA1c by SES increased significantly (p<0.001). After adjusting for technology use, results for DPV did not change whereas the increase in T1DX was no longer significant.</p> <p> </p> <p><b>Conclusions: </b>Although causal conclusions cannot be drawn, diabetes technology use is lowest and HbA1c is highest in those of the lowest SES quintile in the T1DX and this difference for HbA1c broadened in the last decade. Associations of SES with technology use and HbA1c were weaker in the DPV registry. </p>

scholarly journals Domain randomization-enhanced deep learning models for bird detection

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xin Mao ◽  
Jun Kang Chow ◽  
Pin Siang Tan ◽  
Kuan-fu Liu ◽  
Jimmy Wu ◽  
...  
Keyword(s):  
Deep Learning ◽  
Continuous Monitoring ◽  
Bird Species ◽  
Training Data ◽  
Learning Models ◽  
Fine Grained ◽  
Bird Detection ◽  
Relationship Of ◽  
The Relationship

AbstractAutomatic bird detection in ornithological analyses is limited by the accuracy of existing models, due to the lack of training data and the difficulties in extracting the fine-grained features required to distinguish bird species. Here we apply the domain randomization strategy to enhance the accuracy of the deep learning models in bird detection. Trained with virtual birds of sufficient variations in different environments, the model tends to focus on the fine-grained features of birds and achieves higher accuracies. Based on the 100 terabytes of 2-month continuous monitoring data of egrets, our results cover the findings using conventional manual observations, e.g., vertical stratification of egrets according to body size, and also open up opportunities of long-term bird surveys requiring intensive monitoring that is impractical using conventional methods, e.g., the weather influences on egrets, and the relationship of the migration schedules between the great egrets and little egrets.

scholarly journals Association between physical exercise and stroke recurrence among first-ever ischemic stroke survivors

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lisha Hou ◽  
Mier Li ◽  
Ju Wang ◽  
Yawen Li ◽  
Qianwen Zheng ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Exercise Duration ◽  
Stroke Recurrence ◽  
Stroke Survivors ◽  
Face To Face ◽  
Baseline Information ◽  
Exercise Type ◽  
The Relationship

AbstractThe relationship between exercise and stroke recurrence is controversial. This study was designed to test whether an association exists between exercise and ischemic stroke recurrence in first-ever ischemic stroke survivors. Data were collected from January 2010 to June 2016. Baseline information was obtained during face-to-face interviews, and follow-up phone interviews were conducted every 3 months. Exercise type, frequency, intensity, and duration were recorded. Discrete-time survival analysis was used to determine the relationship between exercise and stroke recurrence. 760 first-ever ischemic stroke survivors who were able to exercise were enrolled. After adjusting for covariates, patients who exercised 3.5–7 h per week and more than 7 h per week had a lower relapse risk than patients who did not exercise (3.5–7: OR 0.415; > 7: OR 0.356). Moreover, if the fluctuation of exercise duration was over 4 h, the patients had a higher risk of stroke recurrence than those with variability of less than 2 h (OR 2.153, P = 0.013). Stroke survivors who engage in long-term regular mild exercise (more than 5 sessions per week and lasting on average 40 min per session) have a lower recurrence rate. Irregular exercise increases the risk of stroke recurrence.

scholarly journals HGG-47. DECREASED GROWTH VELOCITY WITH LONG TERM USE OF BRAFV600e AND MEK INHIBITION IN A PATIENT WITH ANAPLASTIC GANGLIOGLIOMA

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii352-iii352
Author(s):  
Hung Tran ◽  
Robert Cooper
Keyword(s):  
Growth Velocity ◽  
Direct Result ◽  
Chromosomal Microarray ◽  
Mek Inhibition ◽  
Follow Up Study ◽  
The Family ◽  
The Relationship

Abstract PURPOSE To describe decreased growth velocity with long term use of BRAFV600e and MEK inhibition in a patient with anaplastic ganglioglioma. RESULTS 4-year-old patient was found to have a 6 x 4.6 x 5 cm mass in the hypothalamus. Pathology consistent with anaplastic ganglioglioma and chromosomal microarray revealed a BRAFV600e mutation. Patient started on dabrafenib and trametinib and tumor decreased 85% after 3 months. She is stable without significant toxicities 39 months on therapy, and is now 8 years old. Patient had been growing at the 25% for weight and 12% for height but is now 65% for weight and 0.5% for height. It is difficult to tease out the relationship between the tumor, the location of the tumor, and the BRAF and MEK inhibitors and their effect on growth. Discussions with the family and endocrinology are ongoing but being &lt;1% for height will lead to decrease in quality of life. CONCLUSIONS Further follow-up study is needed to determine if this is truly a long-term toxicity, or if this may just be a direct result of the location of the tumor. Would supplementation with growth hormone in this patient lead to losing control of a high grade tumor, or would it simply replace a hormone that is not produced?

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