Body Mass Index and Risk of Gastric Cancer in Asian Adults: A Meta-Epidemiological Meta-Analysis of Population-Based Cohort Studies

PurposeA previous meta-analysis (MA) published in 2009 reported that excess body weight was associated with an increased risk of gastric cancer in non-Asians, but not in Asians. The aim was to conduct a meta-epidemiological MA (MEMA) to evaluate association between excess body weight and the risk of gastric cancer in Asian adults with using the proposed classification of weight by body mass index (BMI) in Asian adults.Materials and MethodsThe selection criteria were population-based prospective cohort studies that measured BMI of cohort participants and evaluated a risk of gastric cancer. Overweight group (OW) and obesity group (OB) were defined as 23.0-24.9 and ≥ 25.0, respectively. A group only showing results for BMI over 23.0 was defined as overweight and obesity group (OWB). Random effect model was applied if I2 value was over 50%.ResultsAfter four new studies were added through citation discovery tools, seven cohort studies with 21 datasets were selected finally for MEMA. The I2 value of OW, OB, and OWB were 76.1%, 83.5%, and 97.1%, respectively. Only OWB in men had a I2 value below 50% (22.5%) and showed a statistical significance with inverse association (summary relative risk, 0.79; 95% confidence interval, 0.77 to 0.81).ConclusionThis MEMA supported the hypothesis that OW might be a protective factor in gastric cancer risk in Asian adults. It will be necessary to conduct additional cohort studies with lengthening follow-up periods and re-analyzing the effect of overweight and obesity classified by the Asian criteria.

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Post-Kidney Transplant Visit-to-Visit Body Mass Index Variability as a Risk of Post-Transplant Systolic Hypertension

Current Developments in Nutrition ◽

10.1093/cdn/nzaa063_091 ◽

2020 ◽

Vol 4 (Supplement_2) ◽

pp. 1693-1693

Author(s):

Ekamol Tantisattamo ◽

Natnicha Leelaviwat ◽

Natchaya Polpichai ◽

Chawit Lopimpisuth ◽

Sakditad Saowapa ◽

...

Keyword(s):

Body Mass Index ◽

Body Weight ◽

Kidney Transplant ◽

Median Time ◽

Body Mass ◽

Overweight And Obesity ◽

Absolute Difference ◽

Renal Transplant Recipients ◽

Time To Event ◽

Post Transplant

Abstract Objectives Overweight and obesity are associated with hypertension (HTN) in renal transplant recipients (RTR). Body weight variability is known to be associated with HTN and poor cardiovascular (CV) outcomes in diabetic patients. After successful kidney transplantation (KT), weight change is very common due partly to perioperative and immunological factors. Association between body weight variability and HTN in RTR is unknown. We hypothesize that high body weight variability is associated with post-transplant HTN. Methods Body weight variability of RTR from a single transplant center was assessed as visit-to-visit body mass index variability (VVBMIV) by using average successive variability (ASV = the average absolute difference between successive values of BMI measured at 4, 12, 24, 36, and 48 weeks after KT). Multi-variable Cox proportional hazard regression analysis was used to examine association between post-transplant VVBMIV and systolic and diastolic HTN (SHTN and DHTN), which are defined as SBP and DBP ≥130 and 80 mmHg, respectively. Results Of 104 RTR, mean ± SD age was 54.29 ± 11.65 years and 62% were female. The majority (36%) were obese followed by normal weight (33%), and overweight (31%). Incidence of SBP was 0.041 person-weeks and median time to event was 12.86 weeks; while the incidence of DBP was 0.036 person-weeks with a slightly longer median time-to-event of 13 weeks. Mean ASV of BMI was 1.26 ± 0.82 kg/m2 (0.47 to 2.18). Risk of SHTN is increased 32% for every 1 kg/m2 increase in VVBMIV (HR 1.32, 95%CI 1.04 to 1.68, P 0.022). After adjusted for age, gender, and their interaction terms, very 1 kg/m2 increase in VVBMIV is associated with a 29% greater risk of developing SHTN (HR 1.29, 95% CI 1.01 to 1.65, P 0.043). However, increase in VVBMIV is not associated with an increased risk of DHTN for both univariable (HR 1.15, 95%CI 0.88 to 1.49, P 0.308) and multi-variable Cox regressions models (HR 1.13, 95%CI 0.86 to 1.49, P 0.391). Conclusions Post-kidney transplant VVBMIV is independently associated post-transplant SHTN, but not DHTN. Further studies is needed to examine mechanism of body weight variability and blood pressure outcomes in RTR. Funding Sources None.

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Nutrition Literacy among Adolescents and Its Association with Eating Habits and BMI in Tripoli, Lebanon

Diseases ◽

10.3390/diseases9020025 ◽

2021 ◽

Vol 9 (2) ◽

pp. 25

Author(s):

Sara Taleb ◽

Leila Itani

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Food Habits ◽

Eating Habits ◽

Normal Weight ◽

Overweight And Obesity ◽

Assessment Instrument ◽

Inverse Association ◽

Unhealthy Lifestyle ◽

Cross Sectional

(1) Background: Adolescence is a period of increased autonomy and independent decision making; it determines health behaviors that can persist into the future. Individual factors like food choices and unhealthy lifestyle have an essential role in the development and prevention of obesity among adolescents and are associated with the nutrition literacy of parents and other adults. While the association of parents’ nutrition literacy with adolescent BMI has been addressed, there is still a scarcity of studies that examine the effect of adolescents’ nutrition literacy on their eating habits and body mass index (BMI) status. (2) Methods: A cross-sectional study was conducted that included 189 adolescents (68 with overweight and obesity and 121 with normal weight) aged between 14–19 years from four private schools in Tripoli, Lebanon. A self-administered questionnaire that included the Nutrition Literacy Assessment Instrument (NLAI) and the Adolescent Food Habits Checklist (AFHC) was used. Anthropometrics were measured using standardized procedures. The association between nutrition literacy, food habits and BMI was assessed using a chi squared test for independence and Poisson regression analysis where suitable. (3) Results: Results indicated no association between all five components of nutrition literacy and body mass index categories. Furthermore, there was no association between the Adolescent Food Habits Checklist and overweight or obese BMI status (RR = 0.947, 95%CI: 0.629–1.426) (p = 0.796). No association was observed between nutrition literacy and food habits, except for an inverse association with macronutrients literacy. (4) Conclusions: In conclusion, the study indicated that there was no association between the components of nutrition literacy with body mass index or with food habits, except for macronutrient literacy.

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Body mass index and breast cancer risk in Japan: a pooled analysis of eight population-based cohort studies

Annals of Oncology ◽

10.1093/annonc/mdt542 ◽

2014 ◽

Vol 25 (2) ◽

pp. 519-524 ◽

Cited By ~ 31

Author(s):

K. Wada ◽

C. Nagata ◽

A. Tamakoshi ◽

K. Matsuo ◽

I. Oze ◽

...

Keyword(s):

Breast Cancer ◽

Body Mass Index ◽

Breast Cancer Risk ◽

Cancer Risk ◽

Cohort Studies ◽

Body Mass ◽

Population Based ◽

Pooled Analysis

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Association between Body Mass Index and Prognosis of Colorectal Cancer: A Meta-Analysis of Prospective Cohort Studies

PLoS ONE ◽

10.1371/journal.pone.0120706 ◽

2015 ◽

Vol 10 (3) ◽

pp. e0120706 ◽

Cited By ~ 44

Author(s):

Junga Lee ◽

Jeffrey A. Meyerhardt ◽

Edward Giovannucci ◽

Justin Y. Jeon

Keyword(s):

Colorectal Cancer ◽

Body Mass Index ◽

Cohort Studies ◽

Body Mass ◽

Prospective Cohort ◽

Meta Analysis ◽

Prospective Cohort Studies

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Body Mass Index and Depressive Symptoms: Testing for Adverse and Protective Associations in Two Twin Cohort Studies

Twin Research and Human Genetics ◽

10.1017/thg.2016.14 ◽

2016 ◽

Vol 19 (4) ◽

pp. 306-311 ◽

Cited By ~ 7

Author(s):

Markus Jokela ◽

Venla Berg ◽

Karri Silventoinen ◽

G. David Batty ◽

Archana Singh-Manoux ◽

...

Keyword(s):

Body Mass Index ◽

Depressive Symptoms ◽

Cohort Studies ◽

Body Mass ◽

Genetic Model ◽

The United States ◽

Population Based ◽

The Us ◽

Mz Twins ◽

Pair Analysis

Studies have suggested both adverse and protective associations of obesity with depressive symptoms. We examined the contribution of environmental and heritable factors in this association. Participants were same-sex twin pairs from two population-based twin cohort studies, the Older Finnish Twin Cohort (n = 8,215; mean age = 44.1) and the US Midlife Development in the United States (MIDUS; n = 1,105; mean age = 45.1). Body mass index (BMI) was calculated from self-reported height and weight. Depressive symptoms were assessed using Beck's Depression Inventory (BDI; Finnish Twin Cohort), and by negative and positive affect scales (MIDUS). In the Finnish Twin Cohort, higher BMI was associated with higher depressive symptoms in monozygotic (MZ) twins (B = 2.01, 95% CI = 1.0, 3.0) and dizygotic (DZ) twins (B = 1.17, 0.5, 1.9) with BMI >22. This association was observed in within-pair analysis in DZ twins (B = 1.47, CI = 0.4, 2.6) but not in within-pair analysis of MZ twins (B = 0.03, CI = -1.9, 2.0). Consistent with the latter result, a bivariate genetic model indicated that the association between higher BMI and higher depressive symptoms was largely mediated by genetic factors. The results of twin-pair analysis and bivariate genetic model were replicated in the MIDUS sample. These findings suggest an association between obesity and higher depressive symptoms, which is largely explained by shared heritable biological mechanisms.

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