scholarly journals Focal adhesion complex proteins in epidermis and squamous cell carcinoma

Cell Cycle ◽  
2013 ◽  
Vol 12 (20) ◽  
pp. 3272-3285 ◽  
Author(s):  
Elizabeth Duperret ◽  
Todd W Ridky
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Focal Adhesion ◽  
Squamous Cell ◽  
Focal Adhesion Complex ◽  
Adhesion Complex

Focal adhesion kinase overexpression: Correlation with lymph node metastasis and shorter survival in oral squamous cell carcinoma

Head & Neck ◽  
2012 ◽  
Vol 35 (6) ◽  
pp. 826-830 ◽  
Author(s):  
Juan Carlos de Vicente ◽  
Pablo Rosado ◽  
Paloma Lequerica-Fernández ◽  
Eva Allonca ◽  
Lucas Villallaín ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Focal Adhesion Kinase ◽  
Focal Adhesion ◽  
Squamous Cell ◽  
Node Metastasis

Focal Adhesion Kinase (FAK) Overexpression and Phosphorylation in Oral Squamous Cell Carcinoma and their Clinicopathological Significance

2019 ◽  
Vol 26 (3) ◽  
pp. 1659-1667
Author(s):  
Aki Kato ◽  
Koroku Kato ◽  
Hiroki Miyazawa ◽  
Hisano Kobayashi ◽  
Natsuyo Noguchi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Focal Adhesion Kinase ◽  
Focal Adhesion ◽  
Squamous Cell ◽  
Clinicopathological Significance

scholarly journals The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells

2011 ◽  
Vol 131 (2) ◽  
pp. 287-297 ◽  
Author(s):  
Alan Serrels ◽  
Kenneth McLeod ◽  
Marta Canel ◽  
Andrew Kinnaird ◽  
Kathryn Graham ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Catalytic Activity ◽  
Cell Carcinoma ◽  
Focal Adhesion Kinase ◽  
Focal Adhesion ◽  
Squamous Cell ◽  
Carcinoma Cells ◽  
And Migration ◽  
Proliferation And Migration

Induction of apoptosis of detached oral squamous cell carcinoma cells by safingol. Possible role of Bim, focal adhesion kinase and endonuclease G

APOPTOSIS ◽  
2009 ◽  
Vol 14 (3) ◽  
pp. 287-297 ◽  
Author(s):  
Takayuki Noda ◽  
Soichi Iwai ◽  
Masakazu Hamada ◽  
Yusei Fujita ◽  
Yoshiaki Yura
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Focal Adhesion Kinase ◽  
Focal Adhesion ◽  
Squamous Cell ◽  
Carcinoma Cells ◽  
Endonuclease G ◽  
Induction Of Apoptosis

Involvement of focal adhesion kinase in cellular proliferation, apoptosis and prognosis of laryngeal squamous cell carcinoma

2012 ◽  
Vol 126 (11) ◽  
pp. 1127-1133 ◽  
Author(s):  
D W Li ◽  
Y J Sun ◽  
Z F Sun ◽  
P Dong
Keyword(s):  
Overall Survival ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Focal Adhesion Kinase ◽  
Focal Adhesion ◽  
Squamous Cell ◽  
Cell Apoptosis ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Focal Adhesion Kinase Expression ◽  
Kinase Expression

AbstractObjective:This study aimed to investigate the relationship between focal adhesion kinase expression and clinicopathological factors, cell apoptosis and proliferation, and overall survival, in laryngeal squamous cell carcinoma.Methods:Immunohistochemical staining was used to detect the expression of focal adhesion kinase and proliferating cell nuclear antigen in tissue samples. Apoptotic cells were assessed using the terminal deoxynucleotidyl transferase mediated deoxyuridine triphosphate nick end labelling (‘TUNEL’) method.Results:The proportion of focal adhesion kinase expression was 73.26 per cent in tumour tissues, significantly greater than in normal tissues (p < 0.05), and was significantly related to laryngeal cancer clinical stage, lymph node metastasis and overall survival (p < 0.05). In the tumour cases assessed, up-regulation of focal adhesion kinase expression was significantly associated with decreased cell apoptosis and increased proliferation (p < 0.05).Conclusion:These findings suggest that focal adhesion kinase may affect laryngeal squamous cell carcinoma progression through regulation of cell apoptosis and proliferation. Focal adhesion kinase expression is a major prognostic factor in laryngeal cancer patients.

scholarly journals Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion by targeting focal adhesion pathways in cervical squamous cell carcinoma

2013 ◽  
Vol 42 (5) ◽  
pp. 1523-1532 ◽  
Author(s):  
NORIKO YAMAMOTO ◽  
TAKASHI KINOSHITA ◽  
NIJIRO NOHATA ◽  
TOSHIHIKO ITESAKO ◽  
HIROFUMI YOSHINO ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Migration ◽  
Cell Carcinoma ◽  
Cancer Cell ◽  
Focal Adhesion ◽  
Squamous Cell ◽  
Cervical Squamous Cell Carcinoma ◽  
Migration And Invasion ◽  
Cancer Cell Migration ◽  
Cell Migration And Invasion
Sign in / Sign up

Export Citation Format

Share Document