Beneficial Effects of Sardine Proteins Combined with Citrus latifolia Extract on Lipid profile and Tissues Redox Status in Rats fed a High-Cholesterol Diet

2014 ◽  
Vol 03 (02) ◽  
Author(s):  
Djamil Krouf
Keyword(s):  
Lipid Profile ◽  
Redox Status ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Beneficial Effects ◽  
Citrus Latifolia

Effects of citrus latifolia extract on dyslipidemia and tissues redox status in rats fed a high-cholesterol diet

2019 ◽  
Vol 49 (6) ◽  
pp. 989-999 ◽  
Author(s):  
Hakima Mir ◽  
Djamil Krouf ◽  
Nawal Taleb-Dida ◽  
Sadia Berzou ◽  
Akila Guenzet ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Aqueous Extract ◽  
Thiobarbituric Acid ◽  
Redox Status ◽  
Primary Treatment ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Content Type ◽  
Citrus Latifolia

Purpose This study aims to investigate the possible effect of Citrus latifolia (CL) extract on biomarkers of oxidative stress, including lipid peroxidation products in rats fed a high cholesterol diet Design/methodology/approach Hypercholesterolemia was induced by feeding normocholesterolemic rats 1 per cent cholesterol-enriched diet for 15 days. An experimental group (n = 20) was divided into two groups (n = 10) and fed the same diet with or without CL lyophilized aqueous extract (1 per cent) for four weeks. At day 28, ten rats from each group were killed. Findings Treatment with CL lyophilized aqueous extract compared with the untreated group had decreased plasma total cholesterol (TC) (−36 per cent), triacylglycerols (−48 per cent), isoprostanes values (−74 per cent) and reduced thiobarbituric acid reactive substances in erythrocytes (−21 per cent). However, the supplementation of CL peels in the hypercholesterolemic diet enhanced superoxide dismutase (+69 per cent), glutathione reductase (+30 per cent) and catalase activities (+34 per cent). Originality/value In hypercholesterolemic rats, administering CL extract ameliorates dyslipidemia and attenuates lipid peroxidation in tissues. These results suggest that CL could be beneficial in the primary treatment of hypercholesterolemia and oxidative damage caused by a high-cholesterol diet.

Beneficial effects of soy milk and fiber on high cholesterol diet-induced alteration of gut microbiota and inflammatory gene expression in rats

2015 ◽  
Vol 6 (2) ◽  
pp. 492-500 ◽  
Author(s):  
Seung-Min Lee ◽  
Hye Won Han ◽  
Seung Yun Yim
Keyword(s):  
Gene Expression ◽  
Gut Microbiota ◽  
High Cholesterol Diet ◽  
Soy Milk ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Inflammatory Gene Expression ◽  
Inflammatory Gene ◽  
Beneficial Effects ◽  
Induced Changes

We sought to evaluate whether a soy milk and fiber mixture could improve high cholesterol diet-induced changes in gut microbiota and inflammation.

Effects of dietary flaxseed on vascular contractile function and atherosclerosis during prolonged hypercholesterolemia in rabbits

2006 ◽  
Vol 291 (6) ◽  
pp. H2987-H2996 ◽  
Author(s):  
C. M. C. Dupasquier ◽  
A.-M. Weber ◽  
B. P. Ander ◽  
P. P. Rampersad ◽  
S. Steigerwald ◽  
...  
Keyword(s):  
Vascular Function ◽  
Contractile Function ◽  
Plasma Cholesterol ◽  
Dietary Cholesterol ◽  
Relaxation Response ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Beneficial Effects ◽  
Atherosclerotic Lesions

Dietary flaxseed has significant anti-atherogenic effects. However, the limits of this action and its effects on vascular contractile function are not known. We evaluated the effects of flaxseed supplementation on atherosclerosis and vascular function under prolonged hypercholesterolemic conditions in New Zealand White rabbits assigned to one of four groups for 6, 8, or 16 wk of feeding: regular diet (RG), 10% flaxseed-supplemented diet (FX), 0.5% cholesterol-supplemented diet (CH), and 0.5% cholesterol- and 10% flaxseed-supplemented diet (CF). Cholesterol feeding resulted in elevated plasma cholesterol levels and the development of atherosclerosis. The CF group had significantly less atherosclerotic lesions in the aorta and carotid arteries after 6 and 8 wk than the CH animals. However, the anti-atherogenic effect of flaxseed supplementation was completely attenuated by 16 wk. Maximal tension induced in aortic rings either by KCl or norepinephrine was not impaired by dietary cholesterol until 16 wk. This functional impairment was not prevented by including flaxseed in the high-cholesterol diet. Aortic rings from the cholesterol-fed rabbits exhibited an impaired relaxation response to acetylcholine at all time points examined. Including flaxseed in the high-cholesterol diet completely normalized the relaxation response at 6 and 8 wk and partially restored it at 16 wk. No significant changes in the relaxation response induced by sodium nitroprusside were observed in any of the groups. In summary, dietary flaxseed is a valuable strategy to limit cholesterol-induced atherogenesis as well as abnormalities in endothelial-dependent vasorelaxation. However, these beneficial effects were attenuated during prolonged hypercholesterolemic conditions.

Comparative Effect of Garden Egg Fruit, Oat and Apple on Serum Lipid Profile in Rats Fed a High Cholesterol Diet

2005 ◽  
Vol 4 (4) ◽  
pp. 245-249 ◽  
Author(s):  
James Karho Edijala . ◽  
Samuel Ogheneovo Asa . ◽  
George Edaghogho Eri . ◽  
Uzezi Atomatofa .
Keyword(s):  
Lipid Profile ◽  
Serum Lipid ◽  
Serum Lipid Profile ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Comparative Effect

scholarly journals Effect of Ethanol Extract of Glycine Max (Soy Bean) on Serum Lipid Profile of Fat-Fed Hyperlipidemic Rats

2018 ◽  
Vol 10 (1) ◽  
pp. 21-26
Author(s):  
K Sharmin ◽  
R Ahmed ◽  
A Momtaz ◽  
SA Chowdhury ◽  
NA Maya ◽  
...  
Keyword(s):  
Glycine Max ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Serum Lipid Profile ◽  
Lipid Lowering ◽  
Control Group ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Experimentally Induced

Hypercholesterolemia is one of the important causes of cardiovascular disease related mortality and morbidity and recently it has become a significant issue in public health problem of developing countries. The purpose of the study was to see the effect of glycine max (soy bean) on serum lipid profile of experimentally induced hyperlipidemic rats. Hypercholesterolemia was induced by high cholesterol diet containing 1% cholesterol in olive oil. This study was done on 24 long Norwegian rats (Rattus norvegicus) weighing about 200-210 gram. For convenience, the study was divided into Experiment I and Experiment II. In experiment I, 12 rats were divided into two groups- Group A (n = 6, control group) fed on laboratory diet and Group B (n=6) fed on laboratory diet and soy bean extract for 35 days. In experiment II, the remaining 12 rats were divided into 2 groups, Group C (n=6) were fed on laboratory diet and high cholesterol diet (HCD) for 35 days and Group D (n=6) were fed laboratory diet and high cholesterol diet on initial 10 days and soy bean extract was added along with high cholesterol diet for next 25 days. Serum TC, TG, LDL-C and HDL-C were measured after 35 days. HCD increased TG, TC and LDL-C significantly in group C. Glycine max (soy bean) treated group showed that it decreased plasma TC, TG and LDL-C in experimentally induced hyperlipidemic rats but Glycine max (soy bean) did not show any significant lipid lowering effect in normolipidemic rats. The results of this experimental study indicate that Glycine max can act as a cholesterol lowering agent and thereby can improve cardiovascular functions.Bangladesh J Med Biochem 2017; 10(1): 21-26

Beneficial Effects of Taurine on Cardiac Abnormality in NZB/W F1 Mice Fed with a High-Cholesterol Diet

2009 ◽  
Vol 57 (18) ◽  
pp. 8635-8642 ◽  
Author(s):  
Chih-Yang Huang ◽  
Tsai-Ching Hsu ◽  
Wei-Wen Kuo ◽  
Shih-Ping Wu ◽  
Yueh-Min Lin ◽  
...  
Keyword(s):  
High Cholesterol Diet ◽  
Cardiac Abnormality ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Beneficial Effects

scholarly journals Rice Bran Fermented with Kimchi-Derived Lactic Acid Bacteria Prevents Metabolic Complications in Mice on a High-Fat and -Cholesterol Diet

Foods ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1501
Author(s):  
Sihoon Park ◽  
Hae-Choon Chang ◽  
Jae-Joon Lee
Keyword(s):  
Rice Bran ◽  
Fatty Acid Synthase ◽  
Regulatory Element ◽  
High Density ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
High Fat ◽  
Metabolic Complications ◽  
Beneficial Effects

This aim of this study was to investigate the potential beneficial effects of rice bran powder, fermented by Weissella koreensis DB1 isolated from kimchi, to protect against obesity and dyslipidemia induced by a high-fat and high-cholesterol diet, in a mouse model. Male mice were fed a modified AIN-93M diet containing high fat/high-cholesterol (HFCD), or same diet supplemented with non-fermented rice bran powder (HFCD-RB) or fermented rice bran powder (HFCD-FRB) for 10 weeks. In the HFCD-FRB group, body weight, liver and white fat pads weights, triglyceride (TG), total cholesterol (TC), non-high-density lipopreotein cholesterol (non-HDL-C), insulin, glucose and leptine levels in serum, TG levels and the ratio of fat droplets in the liver, TG levels and fat cell size in adipose tissue were decreased, and (high-density lipopreotein cholesterol) HDL-C and adiponectin levels in serum were increased, compared with the HFCD group. The HFCD-FRB group had significantly lower CCAAT-enhancer-binding potein α (C/EBPα), sterol regulatory element-binding transcription protein-1c (SREBP-1c), fatty acid synthase (FAS), and acetyl CoA carboxylase (ACC) gene expression when compared to the HFCD group. The anti-obesity and hypolipidemic effects were marginally greater in the HFCD-FRB group than in the HFCD-RB group. These results suggest that fermented rice bran powder by Weissella koreensis DB1 may have potential beneficial effects on the obesity-related abnormalities and the dysfunction of lipid metabolism.

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