Visceral leishmaniasis treatment outcome and its determinants in northwest Ethiopia

ObjectivesThis study aimed to assess the clinical pattern and predictors of stroke treatment outcomes among hospitalised patients in Felege Hiwot comprehensive specialised hospital (FHCSH) in northwest Ethiopia.DesignA retrospective cross-sectional study.SettingThe study was conducted medical ward of FHCSH.ParticipantsThe medical records of 597 adult patients who had a stroke were included in the study. All adult (≥18 years) patients who had a stroke had been admitted to the medical ward of FHSCH during 2015–2019 were included in the study. However, patients with incomplete medical records (ie, incomplete treatment regimen and the status of the patients after treatment) were excluded in the study.ResultsIn the present study, 317 (53.1%) were males, and the mean age of the study participants was 61.08±13.76 years. About two-thirds of patients (392, 65.7%) were diagnosed with ischaemic stroke. Regarding clinical pattern, about 203 (34.0%) of patients complained of right-side body weakness and the major comorbid condition identified was hypertension (216, 64.9%). Overall, 276 (46.2%) of them had poor treatment outcomes, and 101 (16.9%) of them died. Patients who cannot read and write (AOR=42.89, 95% CI 13.23 to 111.28, p<0.001), attend primary school (AOR=22.11, 95% CI 6.98 to 55.99, p<0.001) and secondary school (AOR=4.20, 95% CI 1.42 to 12.51, p<0.001), diagnosed with haemorrhagic stroke (AOR=2.68, 95% CI 1.62 to 4.43, p<0.001) and delayed hospital arrival more than 24 hours (AOR=2.92, 95% CI 1.83 to 4.66, p=0.001) were the independent predictors of poor treatment outcome.ConclusionsApproximately half of the patients who had a stroke had poor treatment outcomes. Ischaemic stroke was the most predominantly diagnosed stroke type. Education status, types of stroke and the median time from onset of symptoms to hospitalisation were the predictors of treatment outcome. Health education should be given to patients regarding clinical symptoms of stroke. In addition, local healthcare providers need to consider the above risk factors while managing stroke.

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Prevalence of malnutrition and associated risk factors among adult visceral leishmaniasis patients in Northwest Ethiopia: a cross sectional study

BMC Research Notes ◽

10.1186/1756-0500-7-75 ◽

2014 ◽

Vol 7 (1) ◽

pp. 75 ◽

Cited By ~ 26

Author(s):

Bewketu Mengesha ◽

Mengistu Endris ◽

Yegnasew Takele ◽

Kalehiwot Mekonnen ◽

Takele Tadesse ◽

...

Keyword(s):

Risk Factors ◽

Visceral Leishmaniasis ◽

Cross Sectional Study ◽

Northwest Ethiopia ◽

Sectional Study ◽

Cross Sectional ◽

Associated Risk Factors

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Prevalence estimates of human immunodeficiency virus (HIV) infection among visceral leishmaniasis infected people in Northwest Ethiopia: a systematic review and meta-analysis

BMC Infectious Diseases ◽

10.1186/s12879-020-4935-x ◽

2020 ◽

Vol 20 (1) ◽

Cited By ~ 2

Author(s):

Mehdi Mohebali ◽

Yonas Yimam

Keyword(s):

Systematic Review ◽

Human Immunodeficiency Virus ◽

Visceral Leishmaniasis ◽

Hiv Infection ◽

Meta Analysis ◽

Northwest Ethiopia ◽

Infected People ◽

Immunodeficiency Virus ◽

Prevalence Estimates

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Correction to: Factors associated with poor treatment outcome of tuberculosis in Debre Tabor, northwest Ethiopia

BMC Research Notes ◽

10.1186/s13104-020-05062-w ◽

2020 ◽

Vol 13 (1) ◽

Author(s):

Addisu Melese ◽

Balew Zeleke

Keyword(s):

Treatment Outcome ◽

Northwest Ethiopia ◽

Factors Associated ◽

Poor Treatment ◽

Debre Tabor ◽

Poor Treatment Outcome

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Treatment outcome of tuberculosis patients at Debretabor General Hospital, Amhara, Northwest Ethiopia

10.21203/rs.2.10748/v1 ◽

2019 ◽

Author(s):

Tesfaye Andualem ◽

Wubet Taklual

Keyword(s):

Treatment Outcome ◽

Pulmonary Tuberculosis ◽

Success Rate ◽

General Hospital ◽

Treatment Success ◽

Control Program ◽

Northwest Ethiopia ◽

Treatment Success Rate ◽

Tuberculosis Patients ◽

Good Treatment Outcome

Abstract Introduction Tuberculosis is still a global health problem. Especially, in developing countries where overcrowded and lack of awareness is existed. According to WHO, to monitor the effectiveness of tuberculosis prevention and control program, assessing tuberculosis outcome is important. The aim of this study was to determine treatment outcome of tuberculosis patients in Debretabor General Hospital, Debretabor, Northwest Ethiopia, 2019. Materials and methods A retrospective study was carried out between December 2016 to December 2018 from TB patients attending the health institutions of Debretabor General Hospital. All tuberculosis cases reported between 2016-2018 were reviewed carefully and analyzed. A total of 455 Tb patients were enrolled in this study and data were coded and entered in to the computer for statistical analysis using SPSS version 20 and Epi-info soft wares. Result and Discussion Within the study period a total of 455 study participants were requireted. Tuberculosis type was categorized as 88(18.0%) were smear positive pulmonary tuberculosis, 192(42.2%) were smear negative pulmonary tuberculosis and 181(39.8%) were extra pulmonary tuberculosis. Among the study subjects 86(18.9%) were HIV seropositive. Of the total study subjects, treatment completed (357)78.5%, cured (57)12.%, death (16)3.5%, treatment failure(4)0.9%, transfer out (21)4.6%. Good proportion of TB treatment success rate was in 15-44 yrs 310/326(95.0%) where as poor treatment success rate was in 0-14 years 26/42 (61.9%). Being an urban also has a high treatment success rate310/325(95.4%). 408(89.7%) were successfully treated. Conclusion The treatment success rate of tuberculosis patients was satisfactory 89.7%. In the study, treatment of HIV-TB co-infection need a better attention for good treatment outcome.

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Visceral Leishmaniasis and HIV Co-Infection in Northwest Ethiopia: Antiretroviral Treatment and Burden of Disease among Patients Enrolled in HIV Care

American Journal of Tropical Medicine and Hygiene ◽

10.4269/ajtmh.17-0142 ◽

2018 ◽

Vol 98 (2) ◽

pp. 486-491 ◽

Cited By ~ 5

Author(s):

Johan van Griensven ◽

Tesfa Simegn ◽

Mengistu Endris ◽

Ermias Diro

Keyword(s):

Visceral Leishmaniasis ◽

Burden Of Disease ◽

Antiretroviral Treatment ◽

Northwest Ethiopia ◽

Hiv Care

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A Five Years Tuberculosis Treatment Outcome at Kolla Diba Health Center, Dembia District, Northwest Ethiopia: A Retrospective Cross-sectional Analysis

Journal of Infectious Diseases and Therapy ◽

10.4172/2332-0877.1000101 ◽

2013 ◽

Vol 01 (01) ◽

Cited By ~ 4

Author(s):

Mucheye G. Beza Moges T. Wubie

Keyword(s):

Treatment Outcome ◽

Health Center ◽

Northwest Ethiopia ◽

Tuberculosis Treatment ◽

Cross Sectional ◽

Cross Sectional Analysis ◽

Sectional Analysis ◽

Tuberculosis Treatment Outcome

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Visceral Leishmaniasis-Malaria Coinfection and Their Associated Factors in Patients Attending Metema Hospital, Northwest Ethiopia: Suggestion for Integrated Vector Management

Malaria Research and Treatment ◽

10.1155/2017/6816913 ◽

2017 ◽

Vol 2017 ◽

pp. 1-6 ◽

Cited By ~ 2

Author(s):

Getachew Ferede ◽

Ermias Diro ◽

Sisay Getie ◽

Gebeyaw Getnet ◽

Yegnasew Takele ◽

...

Keyword(s):

Visceral Leishmaniasis ◽

Associated Factors ◽

Cross Sectional Study ◽

Northwest Ethiopia ◽

Cross Sectional ◽

Blood Smears ◽

High Prevalence ◽

Vector Management ◽

History Of ◽

Study Participants

Background. Despite high prevalence of visceral leishmaniasis and malaria in the study area, their coinfection remains unknown. Therefore, this study was aimed to document VL-malaria coinfections and their associated factors. Methods. A cross-sectional study was conducted among clinical suspected VL patients attending Metema hospital, Northwest Ethiopia, from January 2014 to June 2014. Blood sample was tested by rk39 antigen-based DiaMed IT-Leish dipstick and Giemsa stain microscopic examination of thick and thin blood smears for malaria detection was performed. Result. A total of 384 VL suspected patients were included in the study. Out of these, the prevalence of VL was 83 (21.6%) while the prevalence of malaria was 45 (11.7%). Of malaria cases, 40 (89%) were positive for P. falciparum and 5 (11%) positive for P. vivax. The overall prevalence of VL-malaria coinfection was 16 (4.2%). One-hundred eighty (46.9%) study participants have history of travel. Of these, 10 (5.6%) have VL-malaria coinfections. Age less than 5 years was associated with VL-malaria coinfection. Conclusion. This study highlights the importance of performing malaria screening amongst VL patients living in malaria-endemic areas, particularly in patients under five years.

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