scholarly journals The Aromatic Plant <i>Satureja horvatii</i> ssp. <i>macrophylla</i> Induces Apoptosis and Cell Death to the A549 Cancer Cell Line

2015 ◽  
Vol 06 (13) ◽  
pp. 2092-2103 ◽  
Author(s):  
Paraskevi Yfanti ◽  
Anna Batistatou ◽  
Georgios Manos ◽  
Marilena E. Lekka
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Aromatic Plant ◽  
A549 Cancer Cell Line

Synthesis and Anticancer Activity of New Hydrazide-hydrazones and Their Pd(II) Complexes

2019 ◽  
Vol 16 (5) ◽  
pp. 522-532 ◽  
Author(s):  
Bedia Kocyigit-Kaymakcioglu ◽  
Senem Sinem Yazici ◽  
Fatih Tok ◽  
Miriş Dikmen ◽  
Selin Engür ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Anticancer Activity ◽  
Cell Line ◽  
Cancer Cell ◽  
Cytotoxic Effect ◽  
A549 Cells ◽  
Cancer Cell Line ◽  
Fibroblast Cell ◽  
Reference Drug ◽  
A549 Cancer Cell Line

Background: Hydrazones, one of the important classes of organic molecules, are pharmaceutical agents comprising –CO-NH-N=CH- group in the structure therefore and exhibiting significant biological activity. Methods: 5-Chloro-N’-[(substituted)methylidene] pyrazine-2-carbohydrazide (3a-g) and their Pd(II) complexes (4a-h) were synthesized and investigated in vitro anticancer activity on A549, Caco2 cancer and normal 3T3 fibroblast cell lines, using the MTT assay. Results: Anticancer activity screening results revealed that some compounds showed remarkable cytotoxic effect. Among them, 5-chloro-N'-[(4-hydroxyphenyl)methylidene] pyrazine-2-carbohydrazide (3c) displayed higher cytotoxic activity against A549 cancer cell line than the reference drug cisplatin. Conclusion: Compound 3c showed high cytotoxic activity against A549 cancer cell line but it showed low cytotoxic effect against normal 3T3 fibroblast cell line. Antiproliferative and antimetastatic effects of 3c were determined by the real-time monitoring of cell proliferative system (RTCA DP). The cell proliferation, metastatic and invasive activities of A549 cells were decreased due to increased concentration of 3c.

Cytotoxicity and Cell Death Mechanisms Induced by a Novel Bisnaphthalimidopropyl Derivative against the NCI-H460 non-small Lung Cancer Cell Line

2013 ◽  
Vol 13 (3) ◽  
pp. 414-421 ◽  
Author(s):  
Raquel T. Lima ◽  
Gemma A. Barron ◽  
Joanna A. Grabowska ◽  
Giovanna Bermano ◽  
Simranjeet Kaur ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Death ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Lung Cancer Cell Line ◽  
Lung Cancer Cell ◽  
Cell Death Mechanisms

Development and Biological Evaluation of Imidazothiazole propenones as Tubulin Inhibitors that Effectively Triggered Apoptotic Cell Death in Alveolar Lung Cancer Cell Line

2017 ◽  
Vol 2 (22) ◽  
pp. 6480-6487 ◽  
Author(s):  
Ibrahim Bin Sayeed ◽  
Koteswara Rao Garikapati ◽  
Venkata Krishna Kanth Makani ◽  
Apoorva Nagarajan ◽  
Mohd Adil Shareef ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Death ◽  
Cell Line ◽  
Cancer Cell ◽  
Apoptotic Cell ◽  
Cancer Cell Line ◽  
Biological Evaluation ◽  
Lung Cancer Cell Line ◽  
Lung Cancer Cell ◽  
Tubulin Inhibitors

scholarly journals Quinovic acid glycosides purified fraction from Uncaria tomentosa induces cell death by apoptosis in the T24 human bladder cancer cell line

2014 ◽  
Vol 67 ◽  
pp. 222-229 ◽  
Author(s):  
Fabrícia Dietrich ◽  
Samuel Kaiser ◽  
Liliana Rockenbach ◽  
Fabrício Figueiró ◽  
Letícia Scussel Bergamin ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cell Death ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Bladder Cancer Cell Line ◽  
Human Bladder Cancer ◽  
Human Bladder ◽  
Uncaria Tomentosa ◽  
Human Bladder Cancer Cell

Three bufadienolides induce cell death in the human lung cancer cell line CL1‐5 mainly through autophagy

2021 ◽  
Vol 31 ◽  
pp. 127715
Author(s):  
Hui-Chi Huang ◽  
Wen-Te Chang ◽  
Meng-Shiou Lee ◽  
Hsing-Yu Chen ◽  
Yu-Hua Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Death ◽  
Cell Line ◽  
Cancer Cell ◽  
Human Lung ◽  
Cancer Cell Line ◽  
Lung Cancer Cell Line ◽  
Human Lung Cancer ◽  
Lung Cancer Cell ◽  
Induce Cell Death

Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line

BioMetals ◽  
2010 ◽  
Vol 23 (6) ◽  
pp. 997-1013 ◽  
Author(s):  
Jung Jin Hwang ◽  
Ha Na Kim ◽  
Jean Kim ◽  
Dong-Hyung Cho ◽  
Mi Joung Kim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Death ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Mcf 7
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