scholarly journals Effect of ALDH2 Genetic Polymorphism on the Adaptive Change in Alcohol Metabolism Due to Continuous Moderate Alcohol Consumption in Humans

2015 ◽  
Vol 06 (02) ◽  
pp. 195-204 ◽  
Author(s):  
Shunji Oshima ◽  
Takeshi Haseba ◽  
Akihiro Nemoto ◽  
Sachie Siiya ◽  
Tomomasa Kanda ◽  
...  
1990 ◽  
Vol 63 (03) ◽  
pp. 345-348 ◽  
Author(s):  
J Veenastra ◽  
C Kluft ◽  
Th Ockhuizen ◽  
H v d Pol ◽  
M Wedel ◽  
...  

SummaryShort-term effects of moderate alcohol consumption on platelet function, tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI) were studied in two age groups of volunteers (20–30 and 45–55 years), each consisting of eight healthy males. The alcohol (30 g in red port and wine) was consumed during a standard dinner. Two blood samples were drawn: one in the postprandial phase, and one the next morning after fasting overnight. Alcohol consumption tended to increase platelet aggregation and production of hydroxy fatty acids, reduced plasma t-PA activity and increased PAI activity in the postprandial phase. After the overnight fast the effects on t-PA and PAI had disappeared whereas at that time alcohol consumption tended to decrease platelet function. The effects of alcohol on t-PA and PAI activity appeared mainly in the older age group, whereas the t-PA activity in this group was already much lower, irrespective of alcohol consumption.


2008 ◽  
Vol 68 (6) ◽  
pp. 988-995 ◽  
Author(s):  
Pierre Valeix ◽  
Patrice Faure ◽  
Sandrine Bertrais ◽  
Anne-Claire Vergnaud ◽  
Luc Dauchet ◽  
...  

2005 ◽  
Vol 352 (3) ◽  
pp. 245-253 ◽  
Author(s):  
Meir J. Stampfer ◽  
Jae Hee Kang ◽  
Jennifer Chen ◽  
Rebecca Cherry ◽  
Francine Grodstein

2001 ◽  
Vol 1 (3) ◽  
pp. 165-171 ◽  
Author(s):  
Anna Belkovets ◽  
S. Kurilovich ◽  
A. Avkenstyuk ◽  
Dharam P. Agarwal

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