scholarly journals 52 Years of Lassa Fever Outbreaks in Nigeria, 1969–2020: An Epidemiologic Analysis of the Temporal and Spatial Trends

2021 ◽  
Vol 105 (4) ◽  
pp. 974-985
Author(s):  
Dennis E. Agbonlahor ◽  
George O. Akpede ◽  
Christian T. Happi ◽  
Oyewale Tomori

ABSTRACT. The year 2020 made 52 years since the first report of Lassa fever (LF) outbreaks from Nigeria, but what progress has been made in its control? We sought to answer this through an epidemiologic analysis of the temporal and spatial trends of the outbreaks from 1969 to 2020. The analysis showed an overall strengthening of the outbreaks, hallmarked by the change from irregular to regular annual and from limited local to nationwide outbreaks, while there was a sharp contrast between the upward trend in case numbers and downward trend in case fatality. Pending the availability of effective vaccines, greater effort is required to reverse the upward trend in case numbers and sustain the downward trend in case fatality. We discuss the factors associated with the observed trends as well as the prerequisites for further improvements.

2018 ◽  
Vol 20 (3) ◽  
pp. 469-479 ◽  
Author(s):  
Chubashini Shunthirasingham ◽  
Nick Alexandrou ◽  
Kenneth A. Brice ◽  
Helena Dryfhout-Clark ◽  
Ky Su ◽  
...  

Temporal and spatial trends of total air concentrations (gas + particle) of halogenated flame retardants at the Canadian Great Lakes Basin were assessed (2005–2014).


Author(s):  
Jason W Birkett ◽  
John N Lester

Concentrations of total mercury (T-Hg) and methylmercury (MeHg) were determined in surficial sediments from the River Yare, Norfolk, UK over the period 1986–1998, to assess the temporal and spatial trends of contamination arising from a historical point source discharge. The results demonstrate that the spatial distribution pattern follows that of a distinct pollution plume in the sediments with an initial increase 2–3 km downstream from the point source discharge at Whitlingham sewage treatment works (STW) outfall. Temporally, this pollution plume remains evident, although there has been an overall decline in the mean T-Hg concentrations from 5.4 in 1986 to 1.8 mg kg −1 in 1998. The major factor for this improvement has been the reduction in discharge of metals from the STW, together with burial by a fresh overlay of uncontaminated sediments. MeHg concentrations also exhibited a dispersed pollution plume. Mean concentrations of MeHg fluctuated during the study period between 3.3 and 8.5 μg kg −1 . There has been no concomitant decline in MeHg concentrations over this period. MeHg was found to constitute less than 1% of T-Hg concentrations in the sediments. The weak correlations observed between T-Hg and MeHg concentrations indicate external environmental factors have a significant influence on determining MeHg concentrations in the sedimentary compartment.


2015 ◽  
Vol 92 (1) ◽  
pp. 135-149 ◽  
Author(s):  
Jesper H. Andersen ◽  
Jacob Carstensen ◽  
Daniel J. Conley ◽  
Karsten Dromph ◽  
Vivi Fleming-Lehtinen ◽  
...  

2012 ◽  
Vol 171 ◽  
pp. 1-8 ◽  
Author(s):  
Sandy Falk ◽  
Hubertus Brunn ◽  
Christa Schröter-Kermani ◽  
Klaus Failing ◽  
Sebastian Georgii ◽  
...  

2013 ◽  
Vol 134 (5) ◽  
pp. 3971-3971
Author(s):  
Julie N. Oswald ◽  
Whitlow W. L. Au ◽  
Marc O. Lammers ◽  
Michael F. Richlen ◽  
Thomas F. Norris

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